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Journal Articles

Pharmacological Inhibition of miR-126 Enhances Venetoclax Activity in Acute Myeloid Leukemia

Blood blood.2025029875.

https://doi.org/10.1182/blood.2025029875

Published: 2025

Includes: Supplemental data

Journal Articles

The transition from myelodysplastic neoplasm to secondary acute myeloid leukemia is revealed by molecular analysis, while functional drug screening demonstrates novel sensitivity patterns with clinical implication

Blood (2025) 146 (Supplement 1): 4328.

https://doi.org/10.1182/blood-2025-4328

Published: 2025

Journal Articles

Clearance of RAS pathway mutations prior to allogeneic transplant in Acute Myeloid Leukemia are associated with favorable overall and leukemia free survival

Blood (2025) 146 (Supplement 1): 4305.

https://doi.org/10.1182/blood-2025-4305

Published: 2025

Journal Articles

Allosteric inhibition of RAN decreases mir-126 biogenesis in endothelial cells and controls Acute Myeloid Leukemia growth

Melissa Valerio, Guido Marcucci, Le Xuan Truong Nguyen, Nagarajan Vaidehi, Wenyuan Wei, Hyunjun Kang, Ning Ma, Supriyo Bhattacharya, Genevieve Baker, Weidong Hu, Lianjun Zhang, Dinh Hoang Hoa, Bin Zhang, J. Jefferson Perry, Jia Feng, Hongyu Zhang

Blood (2025) 146 (Supplement 1): 3294.

https://doi.org/10.1182/blood-2025-3294

Published: 2025

Journal Articles

Chronic myeloid leukemia (CML) evolution is not encoded in single-cell microstates, but emerges from population-level macrostates

David Frankhouser, Dandan Zhao, Yu-Hsuan Fu, Anupam Dey, Ziang Chen, Jihyun Irizarry, Jennifer Rangel Ambriz, Sergio Branciamore, Denis O'Meally, Jeffrey Trent, Stephen Forman, Ya-Huei Kuo, Adam MacLean, Bin Zhang, Russell Rockne, Guido Marcucci

Blood (2025) 146 (Supplement 1): 5026.

https://doi.org/10.1182/blood-2025-5026

Published: 2025

Journal Articles

Computed tomography quantification of body adiposity and induction outcomes in patients with newly diagnosed acute lymphoblastic leukemia

Jose Tinajero, Hoda Pourhassan, Chandana Lall, Dat Ngo, Vaibhav Agrawal, Paul Koller, Lindsey Murphy, Shukaib Arslan, Yazeed Samara, Amandeep Salhotra, Stephen Forman, Guido Marcucci, Anthony Selwyn Stein, Ibrahim Aldoss, Vinod Pullarkat

Blood (2025) 146 (Supplement 1): 6829.

https://doi.org/10.1182/blood-2025-6829

Published: 2025

Journal Articles

ALTseqTM, a rapid (< 48 hours) whole genome sequencing clinical test for Acute Myeloid Leukemia (AML)

Wayne Jepsen, Jonathan Keats, Sara Byron, Cherie Wesley, Bryce Turner, Christophe Legendre, Tyler Izatt, Tracey White, Amy Stouffer, Lucy Ghoda, Yeneka Campana, Courtney Holden, Jonathan Beteran, Michelle Afkhami, Anthony Selwyn Stein, Tibor Kovacsovics, Jeffrey Trent, Guido Marcucci

Blood (2025) 146 (Supplement 1): 7036.

https://doi.org/10.1182/blood-2025-7036

Published: 2025

Journal Articles

High efficacy of blinatumomab combined with pembrolizumab in patients with relapsed/refractory (r/r) B cell acute lymphoblastic leukemia (B-ALL): primary analysis of a Phase 1/2 study

Blood (2025) 146 (Supplement 1): 3352.

https://doi.org/10.1182/blood-2025-3352

Published: 2025

Journal Articles

Tumor-induced dendritic cell dysfunction impairs T-cell proliferation and confers poor prognosis in high-risk acute lymphoblastic leukemia

Blood (2025) 146 (Supplement 1): 5138.

https://doi.org/10.1182/blood-2025-5138

Published: 2025

Journal Articles

Trial in progress: Pilot trial of olutasidenib maintenance post allogeneic hematopoietic cell transplantation in patients carrying IDH1 mutation with AML, MDS, or CMML

Abhay Singh, Guido Marcucci, Akriti Jain, Ryotaro Nakamura, Claudio Brunstein, Amandeep Salhotra

Blood (2025) 146 (Supplement 1): 4287.

https://doi.org/10.1182/blood-2025-4287

Published: 2025

Journal Articles

Allogeneic hematopoietic stem cell transplantation for acute leukemias of mixed or ambiguous lineage

Blood (2025) 146 (Supplement 1): 4282.

https://doi.org/10.1182/blood-2025-4282

Published: 2025

Journal Articles

Loss of endothelial mir-126 drives age-related reduction of hematopoietic activity

Dandan Zhao, Le Xuan Truong Nguyen, Xubo Gong, Fang Chen, Min-Hsuan Chen, Guido Marcucci, Bin Zhang

Blood (2025) 146 (Supplement 1): 1392.

https://doi.org/10.1182/blood-2025-1392

Published: 2025

Journal Articles

BT1: A CD84-targeting T-cell engager for selective eradication of leukemic stem cells in Acute Myeloid Leukemia

Ottavio Napolitano, Miso Park, Mariam Murtadha, Enrico Caserta, Milad Moloudizargari, Preeti Sharma, James Sanchez, Guido Marcucci, John Williams, Flavia Pichiorri

Blood (2025) 146 (Supplement 1): 3286.

https://doi.org/10.1182/blood-2025-3286

Published: 2025

Journal Articles

Cytokine profiling identifies an IL‑8/IL1RAP‑Pathway–Linked inflammatory phenotype in myeloproliferative neoplasms (MPN) associated with high symptom burden and poor outcomes

Idoroenyi Amanam, Lucy Ghoda, Salman Otoukesh, Yile Zhou, Bin Zhang, Dauh-Lian Chi, Tim Synold, John Williams, Monzr M. Al Malki, Haris Ali, Guido Marcucci

Blood (2025) 146 (Supplement 1): 5593.

https://doi.org/10.1182/blood-2025-5593

Published: 2025

Journal Articles

Exploratory risk score incorporating donor type, MF-HCT high-risk mutations, and day 100 chimerism for outcome stratification in myelofibrosis patients undergoing allogeneic hematopoietic cell transplantation

Idoroenyi Amanam, Lucy Ghoda, Monzr M. Al Malki, Karamjeet Sandhu, Andrew Artz, Amanda Blackmon, Guido Marcucci, Stephen Forman, Ryotaro Nakamura, Salman Otoukesh, Haris Ali

Blood (2025) 146 (Supplement 1): 5592.

https://doi.org/10.1182/blood-2025-5592

Published: 2025

Journal Articles

Competing risk model of relapse versus non-relapse mortality in myelofibrosis patients undergoing allogeneic hematopoietic cell transplantation

Idoroenyi Amanam, Lucy Ghoda, Salman Otoukesh, Andrew Artz, Amanda Blackmon, Karamjeet Sandhu, Guido Marcucci, Stephen Forman, Ryotaro Nakamura, Monzr M. Al Malki, Haris Ali

Blood (2025) 146 (Supplement 1): 5591.

https://doi.org/10.1182/blood-2025-5591

Published: 2025

Journal Articles

Total marrow and lymphoid irradiation (TMLI) with fludarabine-melphalan (FM) conditioning for matched donor hematopoietic cell transplant (HCT) in older patients with Relapsed/Refractory (R/R) disease

Monzr M. Al Malki, Susanta Hui, Dongyun Yang, Sally Mokhtari, Hoda Pourhassan, Matthew Mei, Amanda Blackmon, Firoozeh Sahebi, Amandeep Salhotra, Brian Ball, Shukaib Arslan, Salman Otoukesh, Haris Ali, Guido Marcucci, Ryotaro Nakamura, Stephen Forman, Anthony Selwyn Stein, Jeffrey Wong

Blood (2025) 146 (Supplement 1): 376.

https://doi.org/10.1182/blood-2025-376

Published: 2025

Journal Articles

Day 7 mount sinai acute GVHD international consortium (MAGIC) algorithm probability predicts GVHD and non-GVHD-related non-relapse mortality in a contemporary cohort of allogeneic transplant patients

Blood (2025) 146 (Supplement 1): 2464.

https://doi.org/10.1182/blood-2025-2464

Published: 2025

Journal Articles

Itacitinib in combination with post-transplant cyclophosphamide and tacrolimus (ICT) as GVHD prophylaxis for reduced intensity matched donor peripheral blood stem cell hematopoietic cell transplantation: Interim analysis

Monzr M. Al Malki, Dongyun Yang, Sally Mokhtari, Anissa Bailey, Pooja Rajeevan, Rhiannon Imbeah, Salman Otoukesh, Brian Ball, Paul Koller, Vaibhav Agrawal, Yazeed Samara, Firoozeh Sahebi, Ibrahim Aldoss, Andrew Artz, Guido Marcucci, Stephen Forman, Ryotaro Nakamura, Haris Ali

Blood (2025) 146 (Supplement 1): 2455.

https://doi.org/10.1182/blood-2025-2455

Published: 2025

Journal Articles

Evolutionary divergence of polymorphic HLA residues predicts clinical outcomes after haploidentical stem cell transplantation in patients with AML

Blood (2025) 146 (Supplement 1): 512.

https://doi.org/10.1182/blood-2025-512

Published: 2025

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Pharmacological Inhibition of miR-126 Enhances Venetoclax Activity in Acute Myeloid Leukemia

The transition from myelodysplastic neoplasm to secondary acute myeloid leukemia is revealed by molecular analysis, while functional drug screening demonstrates novel sensitivity patterns with clinical implication

Clearance of RAS pathway mutations prior to allogeneic transplant in Acute Myeloid Leukemia are associated with favorable overall and leukemia free survival

Allosteric inhibition of RAN decreases mir-126 biogenesis in endothelial cells and controls Acute Myeloid Leukemia growth

Chronic myeloid leukemia (CML) evolution is not encoded in single-cell microstates, but emerges from population-level macrostates

Computed tomography quantification of body adiposity and induction outcomes in patients with newly diagnosed acute lymphoblastic leukemia

ALTseqTM, a rapid (< 48 hours) whole genome sequencing clinical test for Acute Myeloid Leukemia (AML)

High efficacy of blinatumomab combined with pembrolizumab in patients with relapsed/refractory (r/r) B cell acute lymphoblastic leukemia (B-ALL): primary analysis of a Phase 1/2 study

Tumor-induced dendritic cell dysfunction impairs T-cell proliferation and confers poor prognosis in high-risk acute lymphoblastic leukemia

Trial in progress: Pilot trial of olutasidenib maintenance post allogeneic hematopoietic cell transplantation in patients carrying IDH1 mutation with AML, MDS, or CMML

Allogeneic hematopoietic stem cell transplantation for acute leukemias of mixed or ambiguous lineage

Loss of endothelial mir-126 drives age-related reduction of hematopoietic activity

BT1: A CD84-targeting T-cell engager for selective eradication of leukemic stem cells in Acute Myeloid Leukemia

Cytokine profiling identifies an IL‑8/IL1RAP‑Pathway–Linked inflammatory phenotype in myeloproliferative neoplasms (MPN) associated with high symptom burden and poor outcomes

Exploratory risk score incorporating donor type, MF-HCT high-risk mutations, and day 100 chimerism for outcome stratification in myelofibrosis patients undergoing allogeneic hematopoietic cell transplantation

Competing risk model of relapse versus non-relapse mortality in myelofibrosis patients undergoing allogeneic hematopoietic cell transplantation

Total marrow and lymphoid irradiation (TMLI) with fludarabine-melphalan (FM) conditioning for matched donor hematopoietic cell transplant (HCT) in older patients with Relapsed/Refractory (R/R) disease

Day 7 mount sinai acute GVHD international consortium (MAGIC) algorithm probability predicts GVHD and non-GVHD-related non-relapse mortality in a contemporary cohort of allogeneic transplant patients

Itacitinib in combination with post-transplant cyclophosphamide and tacrolimus (ICT) as GVHD prophylaxis for reduced intensity matched donor peripheral blood stem cell hematopoietic cell transplantation: Interim analysis

Evolutionary divergence of polymorphic HLA residues predicts clinical outcomes after haploidentical stem cell transplantation in patients with AML

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