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Guido Marcucci
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Journal Articles

Homoharringtonine inhibits the NOTCH/MYC pathway and exhibits antitumor effects in T-cell acute lymphoblastic leukemia

Shanshan Suo, Dandan Zhao, Fenglin Li, Yi Zhang, Sonia Rodriguez-Rodriguez, Le Xuan Truong Nguyen, Lucy Ghoda, Nadia Carlesso, Guido Marcucci, Bin Zhang, Jie Jin
Journal: Blood
Blood (2024) 144 (12): 1343–1347.
https://doi.org/10.1182/blood.2023023400
Published: 2024
Includes: Supplemental data
Journal Articles

Glofitamab stimulates immune cell infiltration of CNS tumors and induces clinical responses in secondary CNS lymphoma

James K. Godfrey, Lei Gao, Geoffrey Shouse, Joo Y. Song, Stacy Pak, Brian Lee, Bihong T. Chen, Avyakta Kallam, John H. Baird, Guido Marcucci, Lucy Ghoda, Stephanie Vauleon, Alexey V. Danilov, Alex F. Herrera, Larry W. Kwak, Lihua E. Budde
Journal: Blood
Blood (2024) 144 (4): 457–461.
https://doi.org/10.1182/blood.2024024168
Published: 2024
Includes: Supplemental data
Journal Articles

A CD38-directed, single-chain T-cell engager targets leukemia stem cells through IFN-γ–induced CD38 expression

Mariam Murtadha, Miso Park, Yinghui Zhu, Enrico Caserta, Ottavio Napolitano, Theophilus Tandoh, Milad Moloudizargari, Alex Pozhitkov, Mahmoud Singer, Ada Alice Dona, Hawa Vahed, Asaul Gonzalez, Kevin Ly, Ching Ouyang, James F. Sanchez, Lokesh Nigam, Amanda Duplan, Arnab Chowdhury, Lucy Ghoda, Ling Li, Bin Zhang, Amrita Krishnan, Guido Marcucci, John C. Williams, Flavia Pichiorri
Journal: Blood
Blood (2024) 143 (16): 1599–1615.
https://doi.org/10.1182/blood.2023021570
Published: 2024
Includes: Supplemental data
Journal Articles

STI-8591, a Novel Tyrosine Kinase Inhibitor, Shows Excellent Antileukemic Activity in FLT3 -Mutated (mut) Acute Myeloid Leukemia (AML)

Yi Zhang, Wenwen Wei, Bin Zhang, Jie Sun, Dandan Zhao, Fang Chen, Yongfang Xu, Yu Qian, Yanchun Zhao, Yutong Zhou, Wanhong Xu, Xiaoying Zhang, Long Mao, Guido Marcucci, Xiao Xu, Jie Jin
Journal: Blood
Blood (2023) 142 (Supplement 1): 5010.
https://doi.org/10.1182/blood-2023-174745
Published: 2023
Journal Articles

Toxicities Associated with Tyrosine Kinase Inhibitor Maintenance Following Allogeneic Hematopoietic Cell Transplantation in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Tamer Othman, Paul B. Koller, NI-Chun Tsai, Dat Ngo, Jason Chen, Amanda Blackmon, Hoda Pourhassan, Vaibhav Agrawal, Idoroenyi Amanam, Brian J. Ball, Salman Otoukesh, Amandeep Salhotra, Shukaib Arslan, Monzr M. Al Malki, Haris Ali, Karamjeet S. Sandhu, Ahmed Aribi, Andrew Artz, Forest Marc Stewart, Eileen Patricia Smith, Anthony Stein, Guido Marcucci, Ryotaro Nakamura, Vinod Pullarkat, Ibrahim Aldoss, Matthew Genyeh Mei
Journal: Blood
Blood (2023) 142 (Supplement 1): 2873.
https://doi.org/10.1182/blood-2023-187460
Published: 2023
Journal Articles

Single Center Retrospective Study of Midostaurin Plus Intensive Chemotherapy for Older Patients with Newly Diagnosed FLT-3 Mutated Acute Myelogenous Leukemia

Jose Tinajero, Dat Ngo, Jianying Zhang, NI-Chun Tsai, Joycelynne Michelle Palmer, Ahmed Aribi, Ibrahim Aldoss, Vaibhav Agrawal, Shukaib Arslan, Idoroenyi Amanam, Hoda Pourhassan, Karamjeet S. Sandhu, Monzr M. Al Malki, Vinod Pullarkat, Pamela S. Becker, Ryotaro Nakamura, Anthony Stein, Guido Marcucci, Andrew Artz, Paul B. Koller, Amandeep Salhotra
Journal: Blood
Blood (2023) 142 (Supplement 1): 5937.
https://doi.org/10.1182/blood-2023-173978
Published: 2023
Journal Articles

Concurrent Versus Sequential or No Triazole Anti-Fungal Therapy in Patients Undergoing 7+3 Plus Midostaurin Induction for FLT-3 Acute Myelogenous Leukemia

Dat Ngo, Jose Tinajero, Jianying Zhang, Anthony Stein, Guido Marcucci, Amandeep Salhotra, Vinod Pullarkat, Karamjeet S. Sandhu, Brian J. Ball, Paul B. Koller
Journal: Blood
Blood (2023) 142 (Supplement 1): 5932.
https://doi.org/10.1182/blood-2023-173973
Published: 2023
Journal Articles

Single-Cell RNA-Seq Reveals Intermediate Cell States and Identifies Features Defining Cellular Heterogeneity in Inv(16) Acute Myeloid Leukemia (AML)

Yu-Hsuan Fu, Lianjun Zhang, Ying-Chieh Chen, David Frankhouser, Lisa Uechi, Denis O'Meally, Sergio Branciamore, Guido Marcucci, Russell C. Rockne, Ya-Huei Kuo
Journal: Blood
Blood (2023) 142 (Supplement 1): 5683.
https://doi.org/10.1182/blood-2023-182484
Published: 2023
Journal Articles

Free Energy Changes at State-Transition Critical Points As a Patient-Specific Biomarker in Acute Myeloid Leukemia

Lisa Uechi, Swetha Vasudevan, Daniella Vilencki, Sergio Branciamore, David Frankhouser, Denis O'Meally, Soheil Meshinchi, Guido Marcucci, Ya-Huei Kuo, Nataly Kravchenko-Balasha, Russell C. Rockne
Journal: Blood
Blood (2023) 142 (Supplement 1): 6012.
https://doi.org/10.1182/blood-2023-190662
Published: 2023
Journal Articles

Transfer of mRNA Encoding CEBPA in Lipid Nanoparticles to CEBPA Mutated Leukemia Cell Line KO52 and Primary AML Reduces Cell Growth and Induces Myeloid Differentiation

Chunxiao Zhang, Brenda Loera, Jianying Zhang, Richard Gelinas, Youmna Kfoury, Jonathan Hoggatt, Guido Marcucci, Pamela S. Becker
Journal: Blood
Blood (2023) 142 (Supplement 1): 7122.
https://doi.org/10.1182/blood-2023-190191
Published: 2023
Journal Articles

Pharmacology of a CpG-Linked Anti-Mir-126 Oligonucleotide Targeting Acute Myeloid Leukemia (AML) in Rats and Non-Human Primates (NHP)

Lucy Ghoda, Kokilah Muthaiyah, Bin Amber Zhang, Marcin Kortylewski, James Simpson, Le Xuan Truong Nguyen, Marjorie Robbins, Guido Marcucci, Tim Synold
Journal: Blood
Blood (2023) 142 (Supplement 1): 5754.
https://doi.org/10.1182/blood-2023-191202
Published: 2023
Journal Articles

Outcomes of Patients Undergoing Fludarabine and Melphalan-Based Conditioning with Post-Transplant Cyclophosphamide for Peripheral Blood Stem Cell Allogeneic Hematopoietic Cell Transplant: Donor Type Effect

Tamer Othman, Paul B. Koller, Dongyun Yang, Sally Mokhtari, Amanda Blackmon, Vaibhav Agrawal, Hoda Pourhassan, Brian J. Ball, Idoroenyi Amanam, Shukaib Arslan, Salman Otoukesh, Karamjeet S. Sandhu, Ibrahim Aldoss, Haris Ali, Amandeep Salhotra, Ahmed Aribi, Andrew Artz, Yazeed Samara, Pamela S. Becker, Vinod Pullarkat, Forest Marc Stewart, Eileen Patricia Smith, Anthony Stein, Guido Marcucci, Stephen J. Forman, Ryotaro Nakamura, Monzr M. Al Malki
Journal: Blood
Blood (2023) 142 (Supplement 1): 2151.
https://doi.org/10.1182/blood-2023-187687
Published: 2023
Journal Articles

Application of State Transition Theory and Treatment Modeling for Predicting Response to Chemotherapy in a Mouse Model of Acute Myeloid Leukemia

Lisa Uechi, Yu-Hsuan Fu, David Frankhouser, Denis O'Meally, Sergio Branciamore, Lianjun Zhang, Man Li, Guido Marcucci, Russell C. Rockne, Ya-Huei Kuo
Journal: Blood
Blood (2023) 142 (Supplement 1): 2961.
https://doi.org/10.1182/blood-2023-190603
Published: 2023
Journal Articles

Exploiting the Metabolic Vulnerability of Leukemic Stem Cells (LSCs) in Inv(16) Acute Myeloid Leukemia (AML) with the Combination of Miristen, a Mir-126 Inhibitor, and Venetoclax

Lianjun Zhang, Dinh Hoa Hoang, Hyunjun Kang, Ying-Chieh Chen, Yu-Hsuan Fu, Khyatiben V. Pathak, Melissa Valerio, Fang Chen, Katrina Estrella, Ralf Buettner, Bin Zhang, Patrick Pirrotte, Guido Marcucci, Ya-Huei Kuo, Le Xuan Truong Nguyen
Journal: Blood
Blood (2023) 142 (Supplement 1): 2953.
https://doi.org/10.1182/blood-2023-186936
Published: 2023
Journal Articles

CD38-Directed, Single-Chain T Cell-Engager Targets Leukemia Stem Cells through IFNγ-Induced CD38 Expression

Mariam Murtadha, Miso Park, Yinghui Zhu, Enrico Caserta, Ottavio Napolitano, Theophilus Tandoh, Milad Moloudizargari, Alexander Pozhitkov, Mahmoud Singer, Ada Alice Dona, Hawa Vahed, Asaul Gonzalez, Kevin Ly, Ching Ouyang, James Sanchez, Lokesh Nigam, Arnab Chowdhury, Lucy Y. Ghoda, Ling Li, Bin Zhang, Amrita Krishnan, Guido Marcucci, John C. Williams, Flavia Pichiorri
Journal: Blood
Blood (2023) 142 (Supplement 1): 2797.
https://doi.org/10.1182/blood-2023-189901
Published: 2023
Journal Articles

Real World Outcomes of Patients with Secondary Acute Myeloid Leukemia Undergoing Allogeneic Hematopoietic Cell Transplantation after Induction with Liposomal Daunorubicin-Cytarabine (CPX-351)

Guneet Kaleka, Dat Ngo, Dongyun Yang, Sally Mokhtari, Guido Marcucci, Ryotaro Nakamura, Vinod Pullarkat, Caspian H. Oliai, Amandeep Salhotra
Journal: Blood
Blood (2023) 142 (Supplement 1): 5938.
https://doi.org/10.1182/blood-2023-183053
Published: 2023
Journal Articles

In Vivo Antileukemic Activity of Ost-01 in Acute Myeloid Leukemia (AML): A Novel Natural Product (NP) from Baccharis Coridifolia

Hyunjun Kang, Dinh Hoa Hoang, Melissa Valerio, Khyatiben V. Pathak, Lianjun Zhang, Ralf Buettner, Fang Chen, Katrina Estrella, William Graff, Ya-Huei Kuo, Bin Zhang, Patrick Pirrotte, Le Xuan Truong Nguyen, Guido Marcucci
Journal: Blood
Blood (2023) 142 (Supplement 1): 1565.
https://doi.org/10.1182/blood-2023-187736
Published: 2023
Journal Articles

Total Marrow and Lymphoid Irradiation (TMLI) -Based Conditioning Regimen in Patients with Acute Leukemia Undergoing Allogeneic Hematopoietic Cell Transplant with Measurable Residual Disease

Amandeep Salhotra, Monzr M. Al Malki, Dongyun Yang, Sally Mokhtari, Ahmed Aribi, Ibrahim Aldoss, Vinod Pullarkat, Ricardo Spielberger, Pamela S. Becker, Karamjeet S. Sandhu, Haris Ali, Amanda Blackmon, Brian J. Ball, Paul B. Koller, Salman Otoukesh, Shukaib Arslan, Vaibhav Agrawal, Firoozeh Sahebi, Susanta Hui, Guido Marcucci, Ryotaro Nakamura, Jeffrey Wong, Anthony Stein
Journal: Blood
Blood (2023) 142 (Supplement 1): 2162.
https://doi.org/10.1182/blood-2023-185034
Published: 2023
Journal Articles

Consolidation with First and Second Allogeneic Transplants in Adults with Relapsed/Refractory B-ALL Following Response to CD19CAR T Cell Therapy

Ibrahim Aldoss, Haoyue Shan, Dongyun Yang, Mary C Clark, Monzr M. Al Malki, Ahmed Aribi, Karamjeet S. Sandhu, Amandeep Salhotra, Vaibhav Agrawal, Hoda Pourhassan, Paul B. Koller, Haris Ali, Andrew Artz, Idoroenyi Amanam, Nicole Karras, Anna Pawlowska, Lindsey Murphy, Joycelynne Michelle Palmer, Guido Marcucci, Anthony Stein, Vinod Pullarkat, Ryotaro Nakamura, Stephen J. Forman
Journal: Blood
Blood (2023) 142 (Supplement 1): 4981.
https://doi.org/10.1182/blood-2023-182058
Published: 2023
Journal Articles

What Is the Optimal Treatment Modality in Molecularly Defined Secondary AML? a Multicenter Cohort Study

Shai Shimony, Jan Philipp Bewersdorf, Rory M. Shallis, Yiwen Liu, Eva Johanna Schaefer, Amer M. Zeidan, Aaron D. Goldberg, Eytan M. Stein, Guido Marcucci, Evan C. Chen, Jorge Ramos, R. Coleman Lindsley, Anthony Selwyn Stein, Daniel J. DeAngelo, Donna S. Neuberg, Richard M Stone, Brian J. Ball, Maximilian Stahl
Journal: Blood
Blood (2023) 142 (Supplement 1): 1478.
https://doi.org/10.1182/blood-2023-172763
Published: 2023