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Enrico Caserta
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Journal Articles

A CD38-directed, single-chain T-cell engager targets leukemia stem cells through IFN-γ–induced CD38 expression

Mariam Murtadha, Miso Park, Yinghui Zhu, Enrico Caserta, Ottavio Napolitano, Theophilus Tandoh, Milad Moloudizargari, Alex Pozhitkov, Mahmoud Singer, Ada Alice Dona, Hawa Vahed, Asaul Gonzalez, Kevin Ly, Ching Ouyang, James F. Sanchez, Lokesh Nigam, Amanda Duplan, Arnab Chowdhury, Lucy Ghoda, Ling Li, Bin Zhang, Amrita Krishnan, Guido Marcucci, John C. Williams, Flavia Pichiorri
Journal: Blood
Blood (2024) 143 (16): 1599–1615.
https://doi.org/10.1182/blood.2023021570
Published: 2024
Includes: Supplemental data
Journal Articles

Herpesvirus Entry Mediator As a Novel Therapeutic Target in Multiple Myeloma

Milad Moloudizargari, Ada Alice Dona, Miso Park, Theophilus Tandoh, Mariam Murtadha, Enrico Caserta, Alexander Pozhitkov, Yinghui Zhu, Ottavio Napolitano, James Sanchez, Lokesh Nigam, Amanda Duplan, Arnab Chowdhury, Lucy Y. Ghoda, Jonathan Keats, Scott R. Goldsmith, Michael Rosenzweig, Amrita Krishnan, John C. Williams, Flavia Pichiorri
Journal: Blood
Blood (2023) 142 (Supplement 1): 3296.
https://doi.org/10.1182/blood-2023-190157
Published: 2023
Journal Articles

CD38-Directed, Single-Chain T Cell-Engager Targets Leukemia Stem Cells through IFNγ-Induced CD38 Expression

Mariam Murtadha, Miso Park, Yinghui Zhu, Enrico Caserta, Ottavio Napolitano, Theophilus Tandoh, Milad Moloudizargari, Alexander Pozhitkov, Mahmoud Singer, Ada Alice Dona, Hawa Vahed, Asaul Gonzalez, Kevin Ly, Ching Ouyang, James Sanchez, Lokesh Nigam, Arnab Chowdhury, Lucy Y. Ghoda, Ling Li, Bin Zhang, Amrita Krishnan, Guido Marcucci, John C. Williams, Flavia Pichiorri
Journal: Blood
Blood (2023) 142 (Supplement 1): 2797.
https://doi.org/10.1182/blood-2023-189901
Published: 2023
Journal Articles

CD84 Is a Therapeutically Targetable Driver of Leukemogenesis Via Disruption of Energy Supply in Acute Myeloid Leukemia

Yinghui Zhu, Miso Park, Mariam Murtadha, Enrico Caserta, Le Xuan Truong Nguyen, Mahmoud Singer, Marc Denisse Estepa, Lokesh Nigam, Ada Alice Dona', James F Sanchez, Theophilus Tandoh, Man Li, Bin Zhang, Ya-Huei Kuo, Guido Marcucci, John C Williams, Flavia Pichiorri
Journal: Blood
Blood (2022) 140 (Supplement 1): 89–90.
https://doi.org/10.1182/blood-2022-170300
Published: 2022
Journal Articles

Sumoylation Inhibition Potentiates Daratumumab Activity Against Multiple Myeloma

Li Du, Wei Liu, Enrico Caserta, Flavia Pichiorri, Steve T Rosen
Journal: Blood
Blood (2022) 140 (Supplement 1): 9972–9973.
https://doi.org/10.1182/blood-2022-158040
Published: 2022
Journal Articles

OM301, a Synthetic Polypeptide Containing the p53TA (Transactivation) Domain, Impairs Mitochondrial Activity and Survival of Myeloma Cells

Lokesh Nigam, Yinghui Zhu, Estelle Troadec, Enrico Caserta, Ada Dona', James F Sanchez, Amrita Y. Krishnan, Le Xuan Truong Nguyen, Guido Marcucci, Flavia Pichiorri
Journal: Blood
Blood (2021) 138 (Supplement 1): 2661.
https://doi.org/10.1182/blood-2021-151506
Published: 2021
Journal Articles

Proteasome Inhibitors Impair the Innate Antiviral Immune Response and Potentiate Pelareorep-Based Viral Therapy in Multiple Myeloma

Ada Dona', PhD, Domenico Viola, Enrico Caserta, PhD, Francesca Besi, PhD, James F Sanchez, PhD, Guido Marcucci, MD, Jonathan J Keats, PhD, Amrita Y. Krishnan, MD, Matt Coffey, PhD, Douglas W. Sborov, MDMSc, Gerard Nuovo, MD, Craig C Hofmeister, MDMPH, Flavia Pichiorri, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1816.
https://doi.org/10.1182/blood-2019-128740
Published: 2019
Journal Articles

First-in-Human Imaging of Multiple Myeloma Using Copper-64-Labeled Daratumumab: Preliminary Results

Amrita Y. Krishnan, MD, Vikram Adhikarla, PhD, Ammar Chaudhry, MD, Joycelynne Palmer, PhD, Erasmus K Poku, PhD, Van Eric Biglang-awa, PharmD, Nicole Bowles, Nitya Nathwani, MD, Michael Rosenzweig, MD, Firoozeh Sahebi, MD, Chatchada Karanes, MD, Jennifer Simpson, James F Sanchez, PhD, David Yamauchi, MD, Maria Parayno, MD, Arnab Chowdhury, PhD, Enrico Caserta, PhD, Anna Wu, PhD, Stephen J Forman, MD, David Colcher, PhD, Paul Yazaki, PhD, John E. Shively, PhD, Flavia Pichiorri, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4394.
https://doi.org/10.1182/blood-2019-126080
Published: 2019
Journal Articles

CD84: A Potential Novel Therapeutic Target in Multiple Myeloma

Emine Gulsen Gunes, PhD, Hadas Lewinsky, Domenico Viola, Enrico Caserta, Michael Rosenzweig, Myo Htut, James F Sanchez, PhD, Ralf Buettner, PhD, Guido Marcucci, Jonathan J Keats, PhD, Amrita Krishnan, MD, Steven T Rosen, Idit Shachar, Flavia Pichiorri, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1924.
https://doi.org/10.1182/blood-2018-99-119655
Published: 2018
Journal Articles

Copper 64–labeled daratumumab as a PET/CT imaging tracer for multiple myeloma

Brief Report
Enrico Caserta, Junie Chea, Megan Minnix, Erasmus K. Poku, Domenico Viola, Steven Vonderfecht, Paul Yazaki, Desiree Crow, Jihane Khalife, James F. Sanchez, Joycelynne M. Palmer, Susanta Hui, Nadia Carlesso, Jonathan Keats, Young Kim, Ralf Buettner, Guido Marcucci, Steven Rosen, John Shively, David Colcher, Amrita Krishnan, Flavia Pichiorri
Journal: Blood
Blood (2018) 131 (7): 741–745.
https://doi.org/10.1182/blood-2017-09-807263
Published: 2018
Includes: Multimedia, Supplemental data
Journal Articles

MiR- 16 Regulates Crosstalk in NF-κB Inflammatory Signaling between Myeloma Cells and Bone Marrow Macrophages

Jihane Khalife, Domenico Viola, BS, Jayeeta Ghose, Robert Weingart, James F Sanchez, Craig C Hofmeister, MDMPH, Amrita Krishnan, MD, Guido Marcucci, MD, Nadia Carlesso, MD PhD, Enrico Caserta, PhD, Flavia Pichiorri, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4351.
https://doi.org/10.1182/blood.V130.Suppl_1.4351.4351
Published: 2017
Journal Articles

Copper-64-Labeled Daratumumab As a PET Imaging Tracer for Multiple Myeloma: Potential Use for Minimal Residual Disease Detection

Enrico Caserta, PhD, Junie Chea, Megan Minnix, Domenico Viola, BS, Steven Vonderfecht, Jonathan J Keats, PhD, James F Sanchez, David Colcher, John E. Shively, Amrita Krishnan, MD, Flavia Pichiorri, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3083.
https://doi.org/10.1182/blood.V130.Suppl_1.3083.3083
Published: 2017
Journal Articles

Leflunomide Inhibits c-Myc Signaling and Impairs Myeloma Cell Growth

Ralf Buettner, PhD, Corey James Morales, BA, BS, Enrico Caserta, PhD, Domenico Viola, BS, Joycelynne M. Palmer, PhD, Xiwei Wu, PhD, Nagarajan Vaidehi, PhD, Hongzhi Li, PhD, Tim Synold, PhD, Amrita Krishnan, MD, Flavia Pichiorri, PhD, Michael Rosenzweig, MD, Steven T. Rosen, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4426.
https://doi.org/10.1182/blood.V130.Suppl_1.4426.4426
Published: 2017
Journal Articles

Exploring the Possibility of Using Herpes Simplex Virus in Oncolytic Virotherapy of Multiple Myeloma

Jayeeta Ghose, Luke Russell, Enrico Caserta, Ramasamy Santhanam, Alena Cristina Jaime-Ramirez, Domenico Viola, Amrita Krishnan, Craig C Hofmeister, Balveen Kaur, Flavia Pichiorri, PhD
Journal: Blood
Blood (2016) 128 (22): 4467.
https://doi.org/10.1182/blood.V128.22.4467.4467
Published: 2016
Journal Articles

Daratumumab Impairs Myeloma Cell Adhesion Mediated Drug Resistance through CD38 Internalization

Jayeeta Ghose, Cesar Terrazas, PhD, Domenico Viola, Enrico Caserta, Amrita Krishnan, Craig C Hofmeister, Abhay Satoskar, MD PhD, Flavia Pichiorri, PhD
Journal: Blood
Blood (2016) 128 (22): 4479.
https://doi.org/10.1182/blood.V128.22.4479.4479
Published: 2016
Journal Articles

Small RNA Deep Sequencing Highlights the Important Contribution of Mirnas in Regulating IRF4/c-Myc Axis in Myeloma Development

Hanna Radomska, Alessandro Canella, Consiglio Jessica, Alberto Rocci, MD, Cascione Luciano, Hector Cordero, Liu Joseph, Enrico Caserta, Santhanam Ramasamy, Yvonne A. Efebera, MD MPH, Stefano Volinia, PhD, Craig C Hofmeister, MD MPH, Flavia Pichiorri, PhD
Journal: Blood
Blood (2015) 126 (23): 1791.
https://doi.org/10.1182/blood.V126.23.1791.1791
Published: 2015
Journal Articles

Interleukin-15 Is a Proto-Oncogene In Acute Large Granular Lymphocyte Leukemia

Anjali Mishra, Ph.D., Shujun Liu, Ph.D., Gregory H Sams, Douglas P Curphey, Ramasamy Santhanam, PhD, Laura J Rush, DVM, PhD, Deanna Schaefer, DVM, Lauren G Falkenberg, Laura Sullivan, Laura Jaroncyk, Xunchang Zou, MS, Harold Fisk, PhD, Jadwiga Labanowska, MS, Enrico Caserta, PhD, Lai-Chu Wu, MD, PhD, Heiko Becker, MD, Sebastian Schwind, MD, Jason C. Chandler, MD, Yue-Zhong Wu, MS, Nyla A. Heerema, Ph.D., Pierluigi Porcu, MD, Ramiro Garzon, MD, Guido Marcucci, MD, Michael A. Caligiuri, MD
Journal: Blood
Blood (2010) 116 (21): 704.
https://doi.org/10.1182/blood.V116.21.704.704
Published: 2010