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Journal Articles

Trial in progress: A phase 1 study to evaluate the safety and preliminary efficacy of arlocabtagene autoleucel (arlo-cel), a GPRC5D-targeted chimeric antigen receptor (CAR) T cell therapy, in combination with mezigdomide (MEZI) in patients (pts) with relapsed/refractory multiple myeloma (RRMM)

Free
Susan Bal, Luciano Costa, Nizar Bahlis, Myo Htut, Omar Nadeem, Krina Patel, Scott Solomon, Jaclyn Davis, Ziyan Guo, Kevin Hsu, Hongxiang Hu, Krishna R. Juluri, Jessica Katz, Timothy Pulham, Safiyyah Ziyad, Sham Mailankody
Journal: Blood
Blood (2025) 146 (Supplement 1): 5807.
https://doi.org/10.1182/blood-2025-5807
Published: 2025
Journal Articles

Safety and efficacy of out-of-specification ciltacabtagene autoleucel (cilta-cel) in Relapsed/Refractory multiple myeloma (RRMM)

Free
Azra Borogovac, Murali Janakiram, NI-Chun Tsai, Ann Morales, James Sanchez, Sarah Lee, Scott Goldsmith, Nitya Nathwani, Firoozeh Sahebi, Michael Rosenzweig, Amrita Krishnan, Myo Htut
Journal: Blood
Blood (2025) 146 (Supplement 1): 405.
https://doi.org/10.1182/blood-2025-405
Published: 2025
Journal Articles

Short survival with BCMA and GPRC5D dual antigen exposed relapsed myeloma- an international myeloma working group immunotherapy database analysis

Free
Murali Janakiram, Thomas Martin, Mrugakshi Dave, Chiung-Yu Huang, Sireesha Asoori, Myo Htut, Andre De Menezes Silva Corraes, Prashant Kapoor, Chris Lau Wai Pan, Carlyn Tan, Saad Usmani, Hira Mian, Roman Hajek, Efstathios Kastritis, Susan Bal, Joaquin Martinez-Lopez, Andrew Cowan, Chandramouli Nagarajan, Wee-Joo Chng, Allison Tso, Hermann Einsele, Amrita Krishnan, Rakesh Popat, Yi Lin, Darren Pan
Journal: Blood
Blood (2025) 146 (Supplement 1): 4598.
https://doi.org/10.1182/blood-2025-4598
Published: 2025
Journal Articles

Assessment of pharmacodynamic efficacy biomarkers from A phase 1, first-in-human study of arlocabtagene autoleucel (arlo-cel) in relapsed and refractory multiple myeloma (RRMM)

Free
Safiyyah Ziyad, Kristina Jordahl, Hongxiang Hu, Ethan Thompson, Susan Bal, Myo Htut, Larry Anderson, Tara Gregory, Luciano Costa, Omar Nadeem, Naomey Sarkis, Ziyan Guo, Wei-Ming Kao, Allison Kaeding, Shari Kaiser, Michael Burgess, Jesús Berdeja
Journal: Blood
Blood (2025) 146 (Supplement 1): 2223.
https://doi.org/10.1182/blood-2025-2223
Published: 2025
Journal Articles

Long-term progression-free survival benefit with ciltacabtagene autoleucel in standard-risk relapsed / refractory multiple myeloma

Free
Luciano Costa, Albert Oriol, Dominik Dytfeld, Salomon Manier, Peter Voorhees, Yi Lin, Myo Htut, Wilfried Roeloffzen, Phoebe Joy Ho, Urvi Shah, Man Zhao, Quanlin Li, Agnes Balogh, Katherine Li, Ana Slaughter, Nina Benachour, Carolina Lonardi, Arnab Ghosh, Huabin Sun, Nikoletta Lendvai, Tamar Lengil, Nitin Patel, Mythili Koneru, Erika Florendo, Octavio Costa, Vrinda Mahajan, Paula Rodriguez-Otero, Christopher Strouse, Keith Stewart, Surbhi Sidana
Journal: Blood
Blood (2025) 146 (Supplement 1): 94.
https://doi.org/10.1182/blood-2025-94
Published: 2025
Journal Articles

Real world efficacy and safety of elranatamab, a BCMA bispecific antibody for patients with relapsed and refractory multiple myeloma: An international myeloma working group immunotherapy database analysis

Free
Rakesh Popat, Oliver Morjaria, Carlyn Tan, Saad Usmani, Alissa Visram, Susan Bal, Luciano Costa, Roman Hajek, Jana Mihalyova, Joaquin Martinez-Lopez, Adolfo Sáez Marín, Meletios Dimopoulos, Efstathios Kastritis, Chandramouli Nagarajan, Shimin Jasmine Chung, Myo Htut, Wee-Joo Chng, Allison Tso, Thomas Martin, Mrugakshi Dave, Chiung-Yu Huang, Andrew Cowan, Hermann Einsele, Yi Lin, Hira Mian
Journal: Blood
Blood (2025) 146 (Supplement 1): 4588.
https://doi.org/10.1182/blood-2025-4588
Published: 2025
Journal Articles

High rates of financial toxicity and time toxicity in patients receiving chimeric antigen receptor therapy and bispecific antibodies for lymphoma and multiple myeloma: A prospective mixed methods study.

Free
Swetha Thiruvengadam, Nishita Matangi, Murali Janakiram, Annie Xiao, Mark Ponce, Brian Lee, Stacy Pak, Benjamin Martini, Diamond Ward, Ryan Chiechi, Diane Smith, John Baird, Azra Borogovac, Elizabeth Budde, Alexey Danilov, Alex Herrera, Myo Htut, James Godfrey, Scott Goldsmith, Avyakta Kallam, Amrita Krishnan, Larry Kwak, Sarah Lee, Matthew Mei, Nitya Nathwani, Michael Rosenzweig, Firoozeh Sahebi, Tycel Phillips, Geoffrey Shouse, Tanya Siddiqi, Brian Sworder, Kimlin Ashing, Nikhil Thiruvengadam, Steven Rosen
Journal: Blood
Blood (2025) 146 (Supplement 1): 6364.
https://doi.org/10.1182/blood-2025-6364
Published: 2025
Journal Articles

Safety and efficacy of standard-of-care ciltacabtagene autoleucel for relapsed/refractory multiple myeloma

Free
Clinical Trials & Observations
Surbhi Sidana, Krina K. Patel, Lauren C. Peres, Radhika Bansal, Mehmet H. Kocoglu, Leyla Shune, Shebli Atrash, Kinaya Smith, Shonali Midha, Christopher Ferreri, Binod Dhakal, Danai Dima, Patrick Costello, Charlotte Wagner, Ran Reshef, Hitomi Hosoya, Lekha Mikkilineni, Djordje Atanackovic, Saurabh Chhabra, Ricardo Parrondo, Omar Nadeem, Hashim Mann, Nilesh Kalariya, Vanna Hovanky, Gabriel De Avila, Ciara L. Freeman, Frederick L. Locke, Melissa Alsina, Sandy Wong, Megan Herr, Myo Htut, Joseph McGuirk, Douglas W. Sborov, Jack Khouri, Thomas Martin, Murali Janakiram, Yi Lin, Doris K. Hansen
Journal: Blood
Blood (2025) 145 (1): 85–97.
https://doi.org/10.1182/blood.2024025945
Published: 2025
Includes: Supplemental data
Journal Articles

Racial and Ethnic Differences in Outcomes of Multiple Myeloma Patients Treated with Idecabtagene Vicleucel or Ciltacabtagene Autoleucel

Free
Lauren C. Peres, Alicia Richards, Surbhi Sidana, Laura B. Oswald, Danai Dima, Aimaz Afrough, Leyla O. Shune, Shonali Midha, Omar Castaneda, Christopher Ferreri, James A Davis, Oren Pasvolsky, Christen M. Dillard, Megan M Herr, Mehmet H. Kocoglu, Shebli Atrash, Brandon Blue, Evguenia Ouchveridze, Joseph P. McGuirk, Charlotte B Wagner, Radhika Bansal, Patrick Costello, Kinaya Smith, Alex Lieberman-Cribbin, Gabriel De Avila, Sneha Purvey, Hitomi Hosoya, Lekha Mikkilineni, Gurbakhash Kaur, Mahmoud R. Gaballa, Peter A. Forsberg, Ciara Louise Freeman, Murali Janakiram, Myo Htut, Sireesha Asoori, Nilesh Kalariya, Djordje Atanackovic, Binod Dhakal, Jack Khouri, Shahzad Raza, Ran Reshef, Melissa Alsina, Frederick L. Locke, Omar Nadeem, Faiz Anwer, Larry D Anderson, Jr., Shambavi Richard, Yi Lin, Thomas Martin, Peter M. Voorhees, Krina K. Patel, Doris K. Hansen, Douglas W Sborov
Journal: Blood
Blood (2024) 144 (Supplement 1): 3785.
https://doi.org/10.1182/blood-2024-210078
Published: 2024
Journal Articles

The Microbiome and Clinical Outcome Among Patients with Multiple Myeloma (MM) Following CD38-Directed Antibody Treatment

Free
Myo Htut, Keehoon Lee, Nitya Nathwani, Michael Rosenzweig, Murali Janakiram, Scott R. Goldsmith, James F. Sanchez, Martha Scott, Jonathan Keats, Amrita Y Krishnan, Steven T. Rosen, Sophia S. Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 1941.
https://doi.org/10.1182/blood-2024-206314
Published: 2024
Journal Articles

Delayed Neurotoxicity after CAR-T in Multiple Myeloma: Results from a Global IMWG Registry

Free
Anupama Deepa Kumar, Suheil Albert Atallah-Yunes, Sridevi Rajeeve, Ahmed Abdelhak, Hamza Hashmi, Andre Corraes, Myo Htut, Paula Rodriguez-Otero, Ricardo D. Parrondo, Saurabh Chhabra, K. Martin Kortüm, Lukas Scheller, Sofie-Katrin Kadel, Hermann Einsele, Niels W.C.J. van de Donk, Jana Mihalyova, Roman Hajek, Joaquin Martinez Lopez, Noa Biran, Carlos Fernández de Larrea, Ingerid Weum Abrahamsen, Szu-Ying Chen, Melissa Ng, Bonell Patino Escobar, Simon J Harrison, Caitlin Costello, Isadora Matos, Edvan Crusoe, Luciano J. Costa, Arun P Wiita, Sasha Gupta, Thomas Martin, Yi Lin, Ajai Chari
Journal: Blood
Blood (2024) 144 (Supplement 1): 4758.
https://doi.org/10.1182/blood-2024-201783
Published: 2024
Journal Articles

BMS-986393, a G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D)-Targeted CAR T Cell Therapy, in Patients (pts) with Relapsed/Refractory (RR) Multiple Myeloma (MM) and 1-3 Prior Regimens: Updated Phase 1 Safety and Efficacy Results

Free
Susan Bal, Myo Htut, Jesús G. Berdeja, Larry D Anderson, Jr., Adriana Rossi, Tara Gregory, Thomas G Martin, Luciano J. Costa, Hongxiang Hu, Jinjie Chen, Chaoqun Mei, Naomey Sarkis, Alok Shrestha, Safiyyah Ziyad, Wei-Ming Kao, Allison J Kaeding, Michael R. Burgess, Omar Nadeem
Journal: Blood
Blood (2024) 144 (Supplement 1): 2069.
https://doi.org/10.1182/blood-2024-203279
Published: 2024
Journal Articles

Efficacy and Safety with Extended Follow-up in a Phase 1 Study of BMS-986393, a G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D)-Targeted CAR T Cell Therapy, in Patients (pts) with Heavily Pretreated Relapsed/Refractory (RR) Multiple Myeloma (MM)

Free
Susan Bal, Larry D Anderson, Jr., Omar Nadeem, Jesús G. Berdeja, Adriana Rossi, Tara Gregory, Mehmet Hakan Koçoğlu, Thomas G Martin, Daniel N. Egan, Luciano J. Costa, Hongxiang Hu, Jinjie Chen, Chaoqun Mei, Naomey Sarkis, Alok Shrestha, Safiyyah Ziyad, Wei-Ming Kao, Allison J Kaeding, Michael R. Burgess, Myo Htut
Journal: Blood
Blood (2024) 144 (Supplement 1): 922.
https://doi.org/10.1182/blood-2024-201356
Published: 2024
Journal Articles

Comparative Safety and Efficacy of Ciltacabtagene Autoleucel and Idecabtagene Vicleucel CAR T-Cell Therapies in Relapsed or Refractory Multiple Myeloma

Free
Doris K. Hansen, Lauren C. Peres, Danai Dima, Alicia Richards, Leyla O. Shune, Aimaz Afrough, Shonali Midha, Binod Dhakal, Mehmet H. Kocoglu, Shebli Atrash, Chris Ferreri, Omar Castaneda, James A Davis, Evguenia Ouchveridze, Joseph P. McGuirk, Charlotte B Wagner, Radhika Bansal, Patrick Costello, Kinaya Smith, Alex Lieberman-Cribbin, Gabriel De Avila, Sneha Purvey, Hitomi Hosoya, Lekha Mikkilineni, Laura B. Oswald, Gurbakhash Kaur, Oren Pasvolsky, Mahmoud R. Gaballa, Megan M Herr, Peter A. Forsberg, Murali Janakiram, Myo Htut, Sireesha Asoori, Nilesh Kalariya, Hamza Hashmi, Ran Reshef, Douglas W Sborov, Omar Nadeem, Faiz Anwer, Jack Khouri, Shahzad Raza, Djordje Atanackovic, Melissa Alsina, Ciara Louise Freeman, Frederick L. Locke, Peter M. Voorhees, Larry D Anderson, Jr., Shambavi Richard, Thomas Martin, Yi Lin, Krina K. Patel, Surbhi Sidana
Journal: Blood
Blood (2024) 144 (Supplement 1): 936.
https://doi.org/10.1182/blood-2024-194390
Published: 2024
Journal Articles

Alternative Lymphodepletion Strategies Lead to Similar Response Rates and Toxicities in Standard-of-Care BCMA-Directed CAR-T Therapy in Relapsed Refractory Multiple Myeloma

Free
Shonali Midha, Ashwath Gurumurthi, Patrick Costello, Robert A. Redd, Ciara Louise L. Freeman, Omar Castaneda, Rebecca Gonzalez, Filip Ionescu, Mahmoud Gaballa, Nilesh Kalariya, Jack Khouri, Danai Dima, Mehmet H. Kocoglu, Douglas Sborov, Charlotte B Wagner, Shebli Atrash, Peter M. Voorhees, Hamza Hashmi, James A Davis, Peter A. Forsberg, Joseph P McGuirk, Leyla Shune, Megan Herr, Ran Reshef, Yi Lin, Myo Htut, Thomas Martin, Surbhi Sidana, Doris K. Hansen, Omar Nadeem, Krina K. Patel
Journal: Blood
Blood (2023) 142 (Supplement 1): 3499.
https://doi.org/10.1182/blood-2023-187565
Published: 2023
Journal Articles

Clonal Hematopoiesis Is Associated with Severe Cytokine Release Syndrome in Patients Treated with Chimeric Antigen Receptor T-Cell (CAR-T) Therapy

Free
Scott R. Goldsmith, Geoffrey P. Shouse, F. Lennie Wong, Alysia Bosworth, Aleksi Iujuridze, Sitong Chen, June-Wha Rhee, Matthew G. Mei, Murali Janakiram, Myo Htut, Stephen J. Forman, Raju Pillai, L. Elizabeth Budde, Saro Armenian
Journal: Blood
Blood (2023) 142 (Supplement 1): 4814.
https://doi.org/10.1182/blood-2023-185157
Published: 2023
Journal Articles

BMS-986393 (CC-95266), a G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D)-Targeted Chimeric Antigen Receptor (CAR) T-Cell Therapy for Relapsed/Refractory Multiple Myeloma (RRMM): Updated Results from a Phase 1 Study

Free
Susan Bal, Myo Htut, Omar Nadeem, Larry D. Anderson, Jr., Hakan Koçoğlu, Tara Gregory, Adriana C Rossi, Tom Martin, Daniel N. Egan, Luciano Costa, Hongxiang Hu, Yanping Chen, Shaoyi Li, Lisa M. Kelly, Naomey Sarkis, Safiyyah Ziyad, Wei-Ming Kao, Allison June Kaeding, Michael R. Burgess, Jésus G Berdeja
Journal: Blood
Blood (2023) 142 (Supplement 1): 219.
https://doi.org/10.1182/blood-2023-181857
Published: 2023
Journal Articles

Prior Immune Effector Cell Therapy, Is Not Associated with an Increased Infectious Risk of Subsequent Bispecific Antibody Therapy for Multiple Myeloma

Free
Lawrence Liu, Scott R. Goldsmith, Sheryl Leahey, Carlos Gomez Luna, Shawn Streeter, Adam Braun, Nitya Nathwani, Michael Rosenzweig, Firoozeh Sahebi, Azra Borogovac, Jonathan Keats, Myo Htut, Arnab Chowdhury, Sanjeet Singh Dadwal, Amrita Krishnan, Murali Janakiram
Journal: Blood
Blood (2023) 142 (Supplement 1): 1987.
https://doi.org/10.1182/blood-2023-188077
Published: 2023
Journal Articles

Universal Updated Phase 1 Data Highlights Role of Allogeneic Anti-BCMA ALLO-715 Therapy for Relapsed/Refractory Multiple Myeloma

Free
Sham Mailankody, Jeffrey V. Matous, Michaela Liedtke, Surbhi Sidana, Olalekan O. Oluwole, Meera Mohan, Jose C. Cruz, Rajneesh Nath, Faiz Anwer, Adriana Rossi, Myo Htut, Shahbaz A. Malik, Srinivas Ghatta, Myles Dillon, Wendy Ying, Lynn Navale, Erin E. Karski, Arun Balakumaran, Shaji K. Kumar
Journal: Blood
Blood (2022) 140 (Supplement 1): 4620–4622.
https://doi.org/10.1182/blood-2022-158231
Published: 2022
Journal Articles

Clinical Activity of BMS-986393 (CC-95266), a G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D)-Targeted Chimeric Antigen Receptor (CAR) T Cell Therapy, in Patients with Relapsed and/or Refractory (R/R) Multiple Myeloma (MM): First Results from a Phase 1, Multicenter, Open-Label Study

Free
Susan Bal, M. Hakan Kocoglu, Omar Nadeem, Myo Htut, Tara Gregory, Larry D. Anderson, Jr., Luciano J. Costa, Tonia J. Buchholz, Safiyyah Ziyad, Meng Li, Yanping Chen, Allison J. Kaeding, Michael R. Burgess, Kristen Hege, Jesus Berdeja
Journal: Blood
Blood (2022) 140 (Supplement 1): 883–885.
https://doi.org/10.1182/blood-2022-162395
Published: 2022