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James F. Sanchez
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Journal Articles

A CD38-directed, single-chain T-cell engager targets leukemia stem cells through IFN-γ–induced CD38 expression

Mariam Murtadha, Miso Park, Yinghui Zhu, Enrico Caserta, Ottavio Napolitano, Theophilus Tandoh, Milad Moloudizargari, Alex Pozhitkov, Mahmoud Singer, Ada Alice Dona, Hawa Vahed, Asaul Gonzalez, Kevin Ly, Ching Ouyang, James F. Sanchez, Lokesh Nigam, Amanda Duplan, Arnab Chowdhury, Lucy Ghoda, Ling Li, Bin Zhang, Amrita Krishnan, Guido Marcucci, John C. Williams, Flavia Pichiorri
Journal: Blood
Blood (2024) 143 (16): 1599–1615.
https://doi.org/10.1182/blood.2023021570
Published: 2024
Includes: Supplemental data
Journal Articles

CD84 Is a Therapeutically Targetable Driver of Leukemogenesis Via Disruption of Energy Supply in Acute Myeloid Leukemia

Yinghui Zhu, Miso Park, Mariam Murtadha, Enrico Caserta, Le Xuan Truong Nguyen, Mahmoud Singer, Marc Denisse Estepa, Lokesh Nigam, Ada Alice Dona', James F Sanchez, Theophilus Tandoh, Man Li, Bin Zhang, Ya-Huei Kuo, Guido Marcucci, John C Williams, Flavia Pichiorri
Journal: Blood
Blood (2022) 140 (Supplement 1): 89–90.
https://doi.org/10.1182/blood-2022-170300
Published: 2022
Journal Articles

OM301, a Synthetic Polypeptide Containing the p53TA (Transactivation) Domain, Impairs Mitochondrial Activity and Survival of Myeloma Cells

Lokesh Nigam, Yinghui Zhu, Estelle Troadec, Enrico Caserta, Ada Dona', James F Sanchez, Amrita Y. Krishnan, Le Xuan Truong Nguyen, Guido Marcucci, Flavia Pichiorri
Journal: Blood
Blood (2021) 138 (Supplement 1): 2661.
https://doi.org/10.1182/blood-2021-151506
Published: 2021
Journal Articles

Total Marrow and Lymphoid Irradiation (TMLI) at a Dose of 2000cGy in Combination with Post-Transplant Cyclophosphamide (PTCy)-Based Graft Versus Host Disease (GvHD) Prophylaxis Is Safe and Associated with Favorable GvHD-Free/Relapse-Free Survival at 1 Year in Patients with Acute Myeloid Leukemia (AML)

Anthony S. Stein, MD, Monzr M. Al Malki, MD, Dongyun Yang, PhD, Joycelynne Palmer, PhD, Ni-Chun Tsai, MS, Ibrahim Aldoss, MD, Haris Ali, MD, Ahmed Aribi, MD, Andrew S. Artz, MD, Len Farol, MD, Susanta Hui, PhD, Chatchada Karanes, Samer Khaled, MD, An Liu, MD, Guido Marcucci, MD, Ryotaro Nakamura, MD, Vinod A. Pullarkat, MD, Eric Radany, MD, Joseph Rosenthal, MD MS, Amandeep Salhotra, MD, James F Sanchez, PhD, Ricardo Spielberger, MD, David S Snyder, MD, Stephen J. Forman, MD, Jeffrey Wong, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 41–42.
https://doi.org/10.1182/blood-2020-141469
Published: 2020
Journal Articles

Phase 1 Results of Anti-PD-Ligand 1 (Durvalumab) & Lenalidomide in Patients with Cutaneous T Cell Lymphoma and Correlation with Programmed Death Ligand 1 Expression and Gene Expression Profile

Christiane Querfeld, MD PhD, Xiwei Wu, PhD, Tracy Stiller, MS, Joycelynne Palmer, PhD, James F Sanchez, PhD, Xochiquetzal Martinez, MD, Steven Rosen, MD, Jasmine Zain, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4024.
https://doi.org/10.1182/blood-2019-126358
Published: 2019
Journal Articles

First-in-Human Imaging of Multiple Myeloma Using Copper-64-Labeled Daratumumab: Preliminary Results

Amrita Y. Krishnan, MD, Vikram Adhikarla, PhD, Ammar Chaudhry, MD, Joycelynne Palmer, PhD, Erasmus K Poku, PhD, Van Eric Biglang-awa, PharmD, Nicole Bowles, Nitya Nathwani, MD, Michael Rosenzweig, MD, Firoozeh Sahebi, MD, Chatchada Karanes, MD, Jennifer Simpson, James F Sanchez, PhD, David Yamauchi, MD, Maria Parayno, MD, Arnab Chowdhury, PhD, Enrico Caserta, PhD, Anna Wu, PhD, Stephen J Forman, MD, David Colcher, PhD, Paul Yazaki, PhD, John E. Shively, PhD, Flavia Pichiorri, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4394.
https://doi.org/10.1182/blood-2019-126080
Published: 2019
Journal Articles

Targeted Marrow Radiation (TMI) Improves Therapeutic Efficacy of STAT3 Decoy Molecules By Augmenting Its Delivery and Immune Modulation in an AML Mouse Model

Srideshikan Sargur Madabushi, PhD, Darren Zuro, Yu-Lin SU, PhD, Paresh Vishwasrao, MSc, Jamison Brooks, B.S, Liliana E Parra, James F Sanchez, PhD, Jeffrey Wong, MD, Marcin Kortylewski, PhD, Susanta Hui, PhD, DABR.
Journal: Blood
Blood (2019) 134 (Supplement_1): 3929.
https://doi.org/10.1182/blood-2019-127470
Published: 2019
Journal Articles

Proteasome Inhibitors Impair the Innate Antiviral Immune Response and Potentiate Pelareorep-Based Viral Therapy in Multiple Myeloma

Ada Dona', PhD, Domenico Viola, Enrico Caserta, PhD, Francesca Besi, PhD, James F Sanchez, PhD, Guido Marcucci, MD, Jonathan J Keats, PhD, Amrita Y. Krishnan, MD, Matt Coffey, PhD, Douglas W. Sborov, MDMSc, Gerard Nuovo, MD, Craig C Hofmeister, MDMPH, Flavia Pichiorri, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1816.
https://doi.org/10.1182/blood-2019-128740
Published: 2019
Journal Articles

Response to Venetoclax and Hypomethylating Agents Among Prognostic Risk Groups and Genetic Subtypes of Acute Myeloid Leukemia

Ibrahim Aldoss, MD, Dongyun Yang, PhD, Raju Pillai, MD, James F Sanchez, PhD, Ahmed Aribi, MD, Haris Ali, MD, Karamjeet S Sandhu, MD, Monzr Al Malki, MD, Matthew Mei, MD, Amandeep Salhotra, MD, Samer K. Khaled, MD, Ryotaro Nakamura, MD, Weili Sun, MD PhD, Margaret R O'Donnell, MD, David S Snyder, MD, Anthony S. Stein, MD, Stephen J Forman, Guido Marcucci, Vinod A. Pullarkat, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 334.
https://doi.org/10.1182/blood-2018-99-113670
Published: 2018
Journal Articles

Immune Mediated Mechanisms of Resistance to Daratumumab

Domenico Viola, Ada Dona, Emine Gulsen Gunes, PhD, Estelle Troadec, Xiwei Wu, Sergio Branciamore, Tinisha McDonald, MS, Lucy Ghoda, PhD, Ashish Streatfield, James F Sanchez, PhD, Chatchada Karanes, Myo Htut, Michael Rosenzweig, Jonathan J Keats, PhD, Steven T Rosen, Guido Marcucci, Amrita Krishnan, MD, Flavia Pichiorri, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3201.
https://doi.org/10.1182/blood-2018-99-117441
Published: 2018
Journal Articles

Repurposing Leflunomide for Relapsed/Refractory Multiple Myeloma: Final Analysis of a Phase 1 Study

Michael Rosenzweig, Joycelynne Palmer, Ni-Chun Tsai, Ralf Buettner, PhD, Lupe Duarte, Myo Htut, Chatchada Karanes, Nitya Nathwani, MD, Flavia Pichiorri, PhD, Firoozeh Sahebi, Tim Synold, Xiwei Wu, James F Sanchez, Amrita Krishnan, MD, Stephen J Forman, Steven T Rosen
Journal: Blood
Blood (2018) 132 (Supplement 1): 2007.
https://doi.org/10.1182/blood-2018-99-120042
Published: 2018
Journal Articles

CD84: A Potential Novel Therapeutic Target in Multiple Myeloma

Emine Gulsen Gunes, PhD, Hadas Lewinsky, Domenico Viola, Enrico Caserta, Michael Rosenzweig, Myo Htut, James F Sanchez, PhD, Ralf Buettner, PhD, Guido Marcucci, Jonathan J Keats, PhD, Amrita Krishnan, MD, Steven T Rosen, Idit Shachar, Flavia Pichiorri, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1924.
https://doi.org/10.1182/blood-2018-99-119655
Published: 2018
Journal Articles

Copper 64–labeled daratumumab as a PET/CT imaging tracer for multiple myeloma

Brief Report
Enrico Caserta, Junie Chea, Megan Minnix, Erasmus K. Poku, Domenico Viola, Steven Vonderfecht, Paul Yazaki, Desiree Crow, Jihane Khalife, James F. Sanchez, Joycelynne M. Palmer, Susanta Hui, Nadia Carlesso, Jonathan Keats, Young Kim, Ralf Buettner, Guido Marcucci, Steven Rosen, John Shively, David Colcher, Amrita Krishnan, Flavia Pichiorri
Journal: Blood
Blood (2018) 131 (7): 741–745.
https://doi.org/10.1182/blood-2017-09-807263
Published: 2018
Includes: Multimedia, Supplemental data
Journal Articles

MiR- 16 Regulates Crosstalk in NF-κB Inflammatory Signaling between Myeloma Cells and Bone Marrow Macrophages

Jihane Khalife, Domenico Viola, BS, Jayeeta Ghose, Robert Weingart, James F Sanchez, Craig C Hofmeister, MDMPH, Amrita Krishnan, MD, Guido Marcucci, MD, Nadia Carlesso, MD PhD, Enrico Caserta, PhD, Flavia Pichiorri, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4351.
https://doi.org/10.1182/blood.V130.Suppl_1.4351.4351
Published: 2017
Journal Articles

Copper-64-Labeled Daratumumab As a PET Imaging Tracer for Multiple Myeloma: Potential Use for Minimal Residual Disease Detection

Enrico Caserta, PhD, Junie Chea, Megan Minnix, Domenico Viola, BS, Steven Vonderfecht, Jonathan J Keats, PhD, James F Sanchez, David Colcher, John E. Shively, Amrita Krishnan, MD, Flavia Pichiorri, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3083.
https://doi.org/10.1182/blood.V130.Suppl_1.3083.3083
Published: 2017
Journal Articles

The miRNA Profile of Cutaneous T Cell Lymphoma Correlates with the Dysfunctional Immunophenotype of the Disease

Christiane Querfeld, MD PhD, Xiwei Wu, PhD, James F Sanchez, PhD, Joycelynne M. Palmer, PhD, Azadeh Motevalli, PhD, Jasmine Zain, MD, Steven T. Rosen, MD
Journal: Blood
Blood (2016) 128 (22): 4132.
https://doi.org/10.1182/blood.V128.22.4132.4132
Published: 2016
Journal Articles

A Phase I/II Trial of Ixazomib (Ix), Pomalidomide (POM), and Dexamethasone (DEX), in Relapsed/Refractory (R/R) Multiple Myeloma (MM) Patients: Responses in Double/Triple Refractory Myeloma and Poor Risk Cytogenetics

Amrita Krishnan, Prashant Kapoor, MD, Joycelynne Palmer, PhD, Ni-Chun Tsai, MS, Shaji Kumar, MD, Sagar Lonial, MD FACP, Myo Htut, MD, Chatchada Karanes, MD, Nitya Nathwani, MD, Michael Rosenzweig, MD, Firoozeh Sahebi, MD, George Somlo, MD FACP, Lupe Duarte, CTA, Stephen J. Forman, MD, James F Sanchez, PhD, Jesus G. Berdeja, MD
Journal: Blood
Blood (2016) 128 (22): 3316.
https://doi.org/10.1182/blood.V128.22.3316.3316
Published: 2016
Journal Articles

Radioimmunotherapy-Based Conditioning with Yttrium-90 Ibritumomab Tiuxetan Plus High Dose BEAM for Non-Hodgkin Lymphoma: Does the Regimen Matter?

Amrita Y. Krishnan, MD, Joycelynne Palmer, PhD, Auayporn P. Nademanee, MD, Robert Chen, Leslie L. Popplewell, MD, Nicole Tsai, MS, James F. Sanchez, PhD, Jennifer Simpson, Ricardo Spielberger, MD, Dave Yamauchi, MD, Stephen J. Forman, MD
Journal: Blood
Blood (2015) 126 (23): 3179.
https://doi.org/10.1182/blood.V126.23.3179.3179
Published: 2015