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Murali Janakiram
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Journal Articles

Safety and Efficacy of Standard of Care Ciltacabtagene Autoleucel for Relapsed/Refractory Multiple Myeloma

Clinical Trials & Observations
Surbhi Sidana, Krina K. Patel, Lauren C Peres, Radhika Bansal, Mehmet Hakan Kocoglu, Leyla Shune, Shebli Atrash, Kinaya Smith, Shonali Midha, Christopher J Ferreri, Binod Dhakal, Danai Dima, Patrick Costello, Charlotte Wagner, Ran Reshef, Hitomi Hosoya, Lekha Mikkilineni, Djordje Atanackovic, Saurabh Chhabra, Ricardo D Parrondo, Omar Nadeem, Hashim Mann, Nilesh Kalariya, Vanna Hovanky, Gabriel DeAvila, Ciara L Freeman, Frederick L Locke, Melissa Alsina, Sandy Wong, Megan M Herr, Myo Htut, Joseph P. McGuirk, Douglas W Sborov, Jack Khouri, Thomas Martin, Murali Janakiram, Yi Lin, Doris K Hansen
Journal: Blood
Blood blood.2024025945.
https://doi.org/10.1182/blood.2024025945
Published: 2024
Includes: Supplemental data
Journal Articles

Clonal Hematopoiesis Is Associated with Severe Cytokine Release Syndrome in Patients Treated with Chimeric Antigen Receptor T-Cell (CAR-T) Therapy

Scott R. Goldsmith, Geoffrey P. Shouse, F. Lennie Wong, Alysia Bosworth, Aleksi Iujuridze, Sitong Chen, June-Wha Rhee, Matthew G. Mei, Murali Janakiram, Myo Htut, Stephen J. Forman, Raju Pillai, L. Elizabeth Budde, Saro Armenian
Journal: Blood
Blood (2023) 142 (Supplement 1): 4814.
https://doi.org/10.1182/blood-2023-185157
Published: 2023
Journal Articles

Efficacy of Bispecific Antibodies Vs CAR-T in the Treatment of Extramedullary Disease and High-Risk Cytogenetics in Relapsed Multiple Myeloma: A Systematic Review and Meta-Analysis

Charan Thej Reddy Vegivinti, Jaison Lawrence Alexander Santhi, Lawrence Liu, Praneeth Reddy Keesari, Rahul Thakur, M Bakri Hammami, Venkatesh Kapu, Sindhu Pericherla, Murali Mohan reddy Gopireddy, Nagarathna Poojary, Ananta Ghimire, Nishi Shah, Murali Janakiram
Journal: Blood
Blood (2023) 142 (Supplement 1): 1994.
https://doi.org/10.1182/blood-2023-190019
Published: 2023
Journal Articles

Prior Immune Effector Cell Therapy, Is Not Associated with an Increased Infectious Risk of Subsequent Bispecific Antibody Therapy for Multiple Myeloma

Lawrence Liu, Scott R. Goldsmith, Sheryl Leahey, Carlos Gomez Luna, Shawn Streeter, Adam Braun, Nitya Nathwani, Michael Rosenzweig, Firoozeh Sahebi, Azra Borogovac, Jonathan Keats, Myo Htut, Arnab Chowdhury, Sanjeet Singh Dadwal, Amrita Krishnan, Murali Janakiram
Journal: Blood
Blood (2023) 142 (Supplement 1): 1987.
https://doi.org/10.1182/blood-2023-188077
Published: 2023
Journal Articles

North American Adult T-Cell Leukemia/Lymphoma Has Frequent Mutations in CCR4 and Responds in Vitro to a Small Molecule CCR4 Antagonist, CCR4-351

B. Hilda Ye, Eric Liu, Kith Pradhan, Erik Guillen, Urvi A Shah, Aditi Shastri, Gregoire Lauvau, Murali Janakiram, Alejandro Sica, Paul D. Kassner, Amit Verma
Journal: Blood
Blood (2023) 142 (Supplement 1): 6108.
https://doi.org/10.1182/blood-2023-191045
Published: 2023
Journal Articles

Monoclonal Gammopathy of Undetermined Significance and Risk of Cardiovascular Disease in US Veterans

Lawrence Liu, Niharika Pant, Mei Wang, Nikhil Grandhi, Ekaterina Proskuriakova, Murali Janakiram, Theodore Thomas, Kristen M. Sanfilippo, Graham Colditz, Daphne R Friedman, Martin William Schoen, Su-Hsin Chang
Journal: Blood
Blood (2023) 142 (Supplement 1): 4773.
https://doi.org/10.1182/blood-2023-185155
Published: 2023
Journal Articles

Allogeneic but Not Autologous Stem Cell Transplantation Improves Outcome in HTLV-1-Associated North American Adult T-Cell Leukemia/Lymphoma

Abdul-Hamid Bazarbachi, Daniel K. Reef, Hiba Narvel, Riya Patel, Rama Al Hamed, Astha Thakkar, Shafia Rahman, Urvi A Shah, Diego Adrianzen Herrera, Ryann Quinn, Sumaira Zareef, Emma Rabinovich, Alyssa De Castro, Felisha Joseph, Kailyn Gillick, Jennat Mustafa, Fariha Khatun, Amanda Lombardo, Latoya Townsend Nugent, Michelly Abreu, Nicole Chambers, Richard Elkind, Yang Shi, Yanhua Wang, Olga Derman, Kira Gritsman, Ulrich Steidl, Mendel Goldfinger, Noah Kornblum, Aditi Shastri, Ioannis Mantzaris, Lizamarie Bachier Rodriguez, Nishi Shah, Dennis Cooper, Ira Braunschweig, Amit Verma, B. Hilda Ye, Murali Janakiram, R. Alejandro Sica
Journal: Blood
Blood (2022) 140 (Supplement 1): 662–664.
https://doi.org/10.1182/blood-2022-170332
Published: 2022
Journal Articles

Factors Associated with Early Mortality in Patients with Multiple Myeloma: A SEER Analysis

John X Wei, Alex Sisto, Aditi Shastri, R. Alejandro Sica, Ioannis Mantzaris, Noah Kornblum, Urvi A Shah, Murali Janakiram, Kira Gritsman, Amit Verma, Mendel Goldfinger, Dennis Cooper, Nishi Shah
Journal: Blood
Blood (2022) 140 (Supplement 1): 11014–11015.
https://doi.org/10.1182/blood-2022-168978
Published: 2022
Journal Articles

CNS Relapse in T-Cell Lymphoma Index: A Risk Score to Predict Central Nervous System Relapse in Patients with T-Cell Lymphomas

Rahul S. Bhansali, Fredrik Ellin, Miao Cao, Thomas Relander, Wenrui Li, Qi Long, Nivetha Ganesan, Robert Stuver, Steven M. Horwitz, Kitsada Wudhikarn, Steven R Hwang, N. Nora Bennani, Julio C. Chavez, Lubomir Sokol, Hayder Saeed, Frank Duan, Pierluigi Porcu, Priyanka Pullarkat, Neha Mehta-Shah, Jasmine Zain, Miguel Ruiz, Jonathan E Brammer, Rishab Prakash, Swami P. Iyer, Adam J. Olszewski, Ajay Major, Sonali M. Smith, Peter A. Riedell, Caroline Goldin, Bradley M. Haverkos, Bei Hu, Pamela B. Allen, Wael Toama, Murali Janakiram, Taylor Brooks, Deepa Jagadeesh, Nisha Hariharan, Aaron M Goodman, Paola Ghione, Fatima Fayyaz, Joanna M. Rhodes, Elise A. Chong, James N. Gerson, Daniel J. Landsburg, Sunita Dwivedy Nasta, Stephen J. Schuster, Jakub Svoboda, Mats Jerkeman, Stefan K. Barta
Journal: Blood
Blood (2022) 140 (Supplement 1): 1481–1484.
https://doi.org/10.1182/blood-2022-160090
Published: 2022
Journal Articles

Adult T-Cell Leukemia/Lymphoma Diagnosed in North American Is Characterized By a Requirement for BCL6 and a Cell Cycle Program Associated with DNA Replication Stress

B. Hilda Ye, Elaine Chung, Xiaoxin Ren, Kith Pradhan, Yanhua Wang, Advaitha Madireddy, Xingxing Zang, Murali Janakiram, R. Alejandro Sica, Amit Verma
Journal: Blood
Blood (2022) 140 (Supplement 1): 8764–8765.
https://doi.org/10.1182/blood-2022-170425
Published: 2022
Journal Articles

Resistance to CD19 Immunotherapy in B-Cell ALL Is Associated with Loss of CD19 and CD22 and an Enhanced Vulnerability to B Cell Receptor Signaling Inhibition

Sarah Aminov, Orsi Giricz, R. Alejandro Sica, Veronika Polishchuk, Bonnie Yates, Hao-Wei Wang, Yanhua Wang, Srabani Sahu, Shanisha Gordon, Carolina Schinke, Kith Pradhan, Srinivas Aluri, Murali Janakiram, Stefan K. Barta, Beamon Agarwal, Mendel Goldfinger, Aditi Shastri, William Matsui, Ulrich Steidl, Joshua Brody, Nirali N. Shah, Samir Parekh, Amit Verma
Journal: Blood
Blood (2022) 140 (Supplement 1): 3480–3482.
https://doi.org/10.1182/blood-2022-169102
Published: 2022
Journal Articles

A Novel Approach to Achieve Long-Lasting Antitumor Immunity in Multiple Myeloma

Metin Gunes, Jessica Dang, Yate-Ching Yuan, Idit Shachar, Murali Janakiram, Mingye Feng, Steven T. Rosen, Emine Gulsen Gunes
Journal: Blood
Blood (2022) 140 (Supplement 1): 7092–7093.
https://doi.org/10.1182/blood-2022-167036
Published: 2022
Journal Articles

Whole-genome landscape of adult T-cell leukemia/lymphoma

Yasunori Kogure, Takuro Kameda, Junji Koya, Makoto Yoshimitsu, Kisato Nosaka, Jun-ichirou Yasunaga, Yoshitaka Imaizumi, Mizuki Watanabe, Yuki Saito, Yuta Ito, Marni B. McClure, Mariko Tabata, Sumito Shingaki, Kota Yoshifuji, Kenichi Chiba, Ai Okada, Nobuyuki Kakiuchi, Yasuhito Nannya, Ayako Kamiunten, Yuki Tahira, Keiichi Akizuki, Masaaki Sekine, Kotaro Shide, Tomonori Hidaka, Yoko Kubuki, Akira Kitanaka, Michihiro Hidaka, Nobuaki Nakano, Atae Utsunomiya, R. Alejandro Sica, Ana Acuna-Villaorduna, Murali Janakiram, Urvi Shah, Juan Carlos Ramos, Tatsuhiro Shibata, Kengo Takeuchi, Akifumi Takaori-Kondo, Yasushi Miyazaki, Masao Matsuoka, Kenji Ishitsuka, Yuichi Shiraishi, Satoru Miyano, Seishi Ogawa, B. Hilda Ye, Kazuya Shimoda, Keisuke Kataoka
Journal: Blood
Blood (2022) 139 (7): 967–982.
https://doi.org/10.1182/blood.2021013568
Published: 2022
Includes: Supplemental data
Journal Articles

Modakafusp Alfa (TAK-573), an Immunocytokine, Shows Clinical Activity in Patients with Relapsed/Refractory Multiple Myeloma; Updated Results from a First-in-Human Phase 1 Study

Dan T. Vogl, Jonathan L. Kaufman, Sarah A. Holstein, Shebli Atrash, Omar Nadeem, Murali Janakiram, Kaveri Suryanarayan, Yuyin Liu, Sabrina Collins, Xavier Parot, Maria Chaudhry
Journal: Blood
Blood (2021) 138 (Supplement 1): 898.
https://doi.org/10.1182/blood-2021-148463
Published: 2021
Journal Articles

Pharmacodynamic Analysis of CAR-T Cell Persistence in Patients with Hematologic Malignancies Treated with NKTR-255, an IL-15 Receptor Agonist That Enhances CD8 + T-Cells: Preliminary Results from a Phase 1 Study

Cameron J. Turtle, Elizabeth Budde, Krina K. Patel, Miguel-Angel Perales, Andrew J. Cowan, Hayder Saeed, Julio C. Chavez, Alexandre V. Hirayama, Delaney R. Kirchmeier, Murali Janakiram, Kai Wu, Lawrence Fong, Zachary Lee, Neha Dixit, Xiaoli Wang, Kazuharu Kai, Mario Q. Marcondes, Jonathan Zalevsky, Nina Shah
Journal: Blood
Blood (2021) 138 (Supplement 1): 2815.
https://doi.org/10.1182/blood-2021-147350
Published: 2021
Journal Articles

Multidisciplinary Provider Insights to Promote Adoption of Bispecific Antibodies to Treat Cancer in the Community

Limaya Atembina, Leigh Boehmer, Kelly Terrell, Rima Koka, Murali Janakiram, Axel Grothey, Amy L Morris, Srinivas Devarakonda, Barbara Rogers, Ronan Kelly, Jesus Berdeja, Firas El Chaer
Journal: Blood
Blood (2021) 138 (Supplement 1): 4033.
https://doi.org/10.1182/blood-2021-153794
Published: 2021
Journal Articles

Low Incidence of Chronic Graft-Versus-Host Disease in Myeloablative Allogeneic Hematopoietic Cell Transplantation with Post-Transplant Cyclophosphamide Using Matched Related or Unrelated Donors: Phase II Study Interim Analysis

Najla H El Jurdi, Daniel O'Leary, Fiona He, Todd E. DeFor, Armin Rashidi, Erica D. Warlick, Ashish O. Gupta, Joseph E. Maakaron, Mukta Arora, Murali Janakiram, Arne Slungaard, Angela R. Smith, Veronika Bachanova, Claudio G. Brunstein, Margaret L. MacMillan, Jeffrey S. Miller, Brian C. Betts, Christen L. Ebens, Heather Stefanski, Troy C Lund, Paul Orchard, Gregory M. Vercellotti, Daniel J. Weisdorf, Shernan G Holtan
Journal: Blood
Blood (2021) 138 (Supplement 1): 1811.
https://doi.org/10.1182/blood-2021-147569
Published: 2021
Journal Articles

Icans Prophylaxis with Simvastatin and Intrathecal Dexamethasone in Adults Receiving Axicabtagene Ciloleucel (Axi‐Cel) Treatment

Joseph Maakaron, Emily Stene, Megan Bruns, Todd E. DeFor, Najla H El Jurdi, Veronika Bachanova, Daniel J. Weisdorf, Jeffrey S. Miller, Murali Janakiram, Mark Juckett
Journal: Blood
Blood (2021) 138 (Supplement 1): 1744.
https://doi.org/10.1182/blood-2021-149607
Published: 2021
Journal Articles

Gda-201, a Novel Metabolically Enhanced Allogeneic Natural Killer (NK) Cell Product Yields High Remission Rates in Patients with Relapsed/Refractory Non-Hodgkin Lymphoma (NHL): 2-Year Survival and Correlation with Cytokine IL7

Veronika Bachanova, Joseph E. Maakaron, Frank Cichocki, David H. McKenna, Qing Cao, Todd E. DeFor, Murali Janakiram, Rose Wangen, Zuzan Cayci, Bartosz Grzywacz, Ronit Simantov, Tracey Lodie, Jeffrey S. Miller
Journal: Blood
Blood (2021) 138 (Supplement 1): 3854.
https://doi.org/10.1182/blood-2021-149989
Published: 2021
Journal Articles

Planned Interim Analysis of a Phase 2 Study of Loncastuximab Tesirine Plus Ibrutinib in Patients with Advanced Diffuse Large B-Cell Lymphoma (LOTIS-3)

Carmelo Carlo-Stella, Pier Luigi Luigi Zinzani, Murali Janakiram, Vivian Dia, Xiaomin He, Annette Ervin-Haynes, Julien Depaus
Journal: Blood
Blood (2021) 138 (Supplement 1): 54.
https://doi.org/10.1182/blood-2021-147765
Published: 2021