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Journal Articles

A Phase 2 trial of AI-BEL (AZT/Interferon-α plus Belinostat) for HTLV-1 related adult T-cell leukemia-lymphoma: Final safety and efficacy Results

Free
Georgios Pongas, Isildinha Reis, Ngoc Toomey, Catalina Amador, Yi Zhou, Erik Guillen, Gregoire Lauvau, B. Hilda Ye, Jennifer Chapman, Juan Carlos Ramos
Journal: Blood
Blood (2025) 146 (Supplement 1): 563.
https://doi.org/10.1182/blood-2025-563
Published: 2025
Journal Articles

BCL-2 inhibition in North American adult T-cell leukemia/lymphoma: Preclinical insights and early clinical outcomes

Free
Ankit Tanwar, Emma Cordover, Salman Sadullah Usmani, Zixuan Tong, Kith Pradhan, Ella Wesson, Latoya S Townsend, Ioannis Mantzaris, Mendel Goldfinger, Nishi Shah, Aditi Shastri, Noah Kornblum, Dennis Cooper, Ridhi Gupta, Nechama Dreyfus, Julie Nguyen, Lauren Shapiro, Eric Feldman, Beth McLellan, Alyssa de Castro, Buse Eglenen Polat, Xingxing Zang, Ali Bazarbachi, Murali Janakiram, Gregoire Lauvau, Kira Gritsman, B. Hilda Ye, Amit Verma, Marina Konopleva, R. Alejandro Sica
Journal: Blood
Blood (2025) 146 (Supplement 1): 3304.
https://doi.org/10.1182/blood-2025-3304
Published: 2025
Journal Articles

Clinical features and outcomes of adult T-cell leukemia/lymphoma across world regions: An international retrospective cohort study

Free
Bryan Valcarcel, Haruhiko Sano, Atae Utsunomiya, Maki Otsuka, Masaharu Miyahara, Yasushi Takamatsu, Kenji Ishitsuka, Shinya Kimura, Junji Suzumiya, Kazuo Tamura, Daniel Enriquez, Jule Vasquez, Brady Beltran, Denisse Castro, Thanya Runciman, Henry Quintero, Elizabeth Arrieta, Oriana Arias, Eduardo Gotuzzo, Gabriela Garrido, Macarena Roa, Nancy Fiad, Abat Khan, Jose Sandoval-Sus, R. Alejandro Sica, Hilda Ye, Murali Janakiram, Ankit Tanwar, Emma Cordover, Lamisha Shah, Fatima Tuz Zahra, Yumeng Zhang, Britney Bell, Lucy Cook, Eliana Miranda, Hiroo Katsuya, Juan Carlos Ramos, Carlos Chiattone, Luis Malpica
Journal: Blood
Blood (2025) 146 (Supplement 1): 3636.
https://doi.org/10.1182/blood-2025-3636
Published: 2025
Journal Articles

Venetoclax Alone or in Combination Shows Promising Activity in Preclinical Models and Clinical Cases of Relapsed/Refractory North American Adult T-Cell Leukemia Lymphoma

Free
Ankit Tanwar, Emma Cordover, Shikhar Sharma, Zixuan Tong, Kith Pradhan, Latoya S Townsend, Ioannis Mantzaris, Mendel Goldfinger, Nishi Shah, Aditi Shastri, Noah Kornblum, Dennis L Cooper, Ridhi Gupta, Simon Zhen, Nechama Dreyfus, Julie Nguyen, Lauren Shapiro, Eric J. Feldman, Ira Braunschweig, Beth McLellan, Alyssa de Castro, Xingxing Zang, Ali Bazarbachi, Murali Janakiram, Erik Guillen, Gregoire Lauvau, Eric Liu, Kira Gritsman, B. Hilda Ye, Amit Verma, Marina Konopleva, R. Alejandro Sica
Journal: Blood
Blood (2024) 144 (Supplement 1): 2791.
https://doi.org/10.1182/blood-2024-206160
Published: 2024
Journal Articles

Impact of Age and Race on Survival in Adult T-Cell Leukemia/Lymphoma in the United States

Free
Madeline G D'Agostino, B. Hilda Ye, Murali Janakiram, Dennis L Cooper, Ioannis Mantzaris, Aditi Shastri, Mendel Goldfinger, Noah Kornblum, Nishi Shah, Amit Verma, Lauren Shapiro, Ridhi Gupta, Yang Shi, Yanhua Wang, Alyssa De Castro, John X Wei, R. Alejandro Sica
Journal: Blood
Blood (2024) 144 (Supplement 1): 7732.
https://doi.org/10.1182/blood-2024-208561
Published: 2024
Journal Articles

Post-Transplantation Cyclophosphamide and Abatacept Graft-Versus-Host-Disease Prophylaxis Shows Improved Outcomes in North American Adult T-Cell Leukemia/Lymphoma

Free
Julie Nguyen, Abdul-Hamid Bazarbachi, Kith Pradhan, John Yan, Emma Cordover, Daniel K Reef, Riya Patel, Rama Al Hamed, Astha Thakkar, Shafia Rahman, Diego Adrianzen Herrera, Ryann Quinn, Alyssa de Castro, Kailyn Gillick, Jennat Mustafa, Fariha Khatun, Amanda Lombardo, Latoya S Townsend, Michelly Abreu, Nicole Chambers, Richard Elkind, Yang Shi, Yanhua Wang, Olga Derman, Kira Gritsman, Ulrich Steidl, Mendel Goldfinger, Noah Kornblum, Aditi Shastri, Ioannis Mantzaris, Lizamarie Bachier Rodriguez, Brittany Moavero, Jhannine Verceles, Angela Czavar, Lauren Shapiro, Trent Wang, Juan Carlos Ramos, Nishi Shah, Ridhi Gupta, Marina Konopleva, Ira Braunschweig, Amit Verma, B. Hilda Ye, Murali Janakiram, Dennis L Cooper, R. Alejandro Sica
Journal: Blood
Blood (2024) 144 (Supplement 1): 7367.
https://doi.org/10.1182/blood-2024-207521
Published: 2024
Journal Articles

Mogamulizumab Shows Significant Activity with Tolerable Toxicity in a Real-World North American Adult T-Cell Leukemia/Lymphoma (ATLL) Cohort

Free
Emma Cordover, Kith Pradhan, Latoya S. Townsend, Mendel Goldfinger, Ioannis Mantzaris, Nishi Shah, Aditi Shastri, Noah Kornblum, Dennis L Cooper, Ridhi Gupta, Lauren Shapiro, Kira Gritsman, Marina Konopleva, Alyssa de Castro, Roy Browne, Salvatore Lia, Amit Verma, Ali Bazarbachi, B. Hilda Ye, Murali Janakiram, R. Alejandro Sica
Journal: Blood
Blood (2024) 144 (Supplement 1): 6418.
https://doi.org/10.1182/blood-2024-210619
Published: 2024
Journal Articles

Promising Safety and Efficacy Data for Peginterferon Alfa-2a (PEG-IFN) and Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy) in a North American Adult T-Cell Leukemia Lymphoma (NA-ATLL) Cohort of Patients

Free
Nechama Dreyfus, Emma Cordover, Kith Pradhan, Latoya S Townsend, Mendel Goldfinger, Ioannis Mantzaris, Nishi Shah, Aditi Shastri, Noah Kornblum, Dennis L Cooper, Ridhi Gupta, Lauren Shapiro, Kira Gritsman, Marina Konopleva, Beth McLellan, Simon Zhen, Alyssa de Castro, Salvatore Lia, Virleny Garcia, Roy Browne, Eric Meyerowitz, Yoram Puius, Margaret McCort, Yang Shi, Yanhua Wang, Amit Verma, B. Hilda Ye, Murali Janakiram, Abdul-Hamid Bazarbachi, R. Alejandro Sica
Journal: Blood
Blood (2024) 144 (Supplement 1): 3067.
https://doi.org/10.1182/blood-2024-208199
Published: 2024
Journal Articles

Safety and Efficacy of AZT-Interferon-α with Belinostat (AI-BEL) for HTLV-1 Related Adult T-Cell Leukemia-Lymphoma

Free
Georgios Pongas, Ngoc Toomey, Isildinha Reis, Jennifer R. Chapman-Fredricks, Yi Zhou, Erik Guillen, Eric Liu, Gregoire Lauvau, B. Hilda Ye, Juan Carlos Ramos
Journal: Blood
Blood (2024) 144 (Supplement 1): 1720.
https://doi.org/10.1182/blood-2024-209155
Published: 2024
Journal Articles

Acetyl Transferase EP300 Deficiency Leads to Chronic Replication Stress in Adult T-Cell Leukemia/Lymphoma

Free
Mrunmai Niljikar, Aastha Juwarwala, Julia Gagliardi, Ranran Zhang, B. Hilda Ye, Advaitha Madireddy
Journal: Blood
Blood (2023) 142 (Supplement 1): 1404.
https://doi.org/10.1182/blood-2023-187061
Published: 2023
Journal Articles

North American Adult T-Cell Leukemia/Lymphoma Has Frequent Mutations in CCR4 and Responds in Vitro to a Small Molecule CCR4 Antagonist, CCR4-351

Free
B. Hilda Ye, Eric Liu, Kith Pradhan, Erik Guillen, Urvi A Shah, Aditi Shastri, Gregoire Lauvau, Murali Janakiram, Alejandro Sica, Paul D. Kassner, Amit Verma
Journal: Blood
Blood (2023) 142 (Supplement 1): 6108.
https://doi.org/10.1182/blood-2023-191045
Published: 2023
Journal Articles

Outcomes Analysis of T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma (T-ALL/T-LBL) in a Minority Rich Cohort

Free
Karun Neupane, Abdul-Hamid Bazarbachi, Daniel K. Reef, Kith Pradhan, Hiba Narvel, Alyssa De Castro, Felisha Joseph, Kailyn Gillick, Fariha Khatun, Amanda Lombardo, Yang Shi, Yanhua Wang, Kira Gritsman, Ulrich Steidl, Mendel Goldfinger, Noah Kornblum, Aditi Shastri, Ioannis Mantzaris, Lizamarie Bachier Rodriguez, Nishi Shah, Dennis Cooper, Ira Braunschweig, Amit Verma, Bin Hilda Ye, Marina Konopleva, R. Alejandro Sica
Journal: Blood
Blood (2022) 140 (Supplement 1): 11595–11597.
https://doi.org/10.1182/blood-2022-159826
Published: 2022
Journal Articles

Allogeneic but Not Autologous Stem Cell Transplantation Improves Outcome in HTLV-1-Associated North American Adult T-Cell Leukemia/Lymphoma

Free
Abdul-Hamid Bazarbachi, Daniel K. Reef, Hiba Narvel, Riya Patel, Rama Al Hamed, Astha Thakkar, Shafia Rahman, Urvi A Shah, Diego Adrianzen Herrera, Ryann Quinn, Sumaira Zareef, Emma Rabinovich, Alyssa De Castro, Felisha Joseph, Kailyn Gillick, Jennat Mustafa, Fariha Khatun, Amanda Lombardo, Latoya Townsend Nugent, Michelly Abreu, Nicole Chambers, Richard Elkind, Yang Shi, Yanhua Wang, Olga Derman, Kira Gritsman, Ulrich Steidl, Mendel Goldfinger, Noah Kornblum, Aditi Shastri, Ioannis Mantzaris, Lizamarie Bachier Rodriguez, Nishi Shah, Dennis Cooper, Ira Braunschweig, Amit Verma, B. Hilda Ye, Murali Janakiram, R. Alejandro Sica
Journal: Blood
Blood (2022) 140 (Supplement 1): 662–664.
https://doi.org/10.1182/blood-2022-170332
Published: 2022
Journal Articles

The Cause and Consequence of Replication Stress in Adult T-Cell Leukemia

Free
Angelica Barreto-Galvez, Advaitha Madireddy, B. Hilda Ye, Julia Gagliardi, Aastha Juwarwala, Archana Pradeep, Mrunmai Niljikar
Journal: Blood
Blood (2022) 140 (Supplement 1): 11512.
https://doi.org/10.1182/blood-2022-167475
Published: 2022
Journal Articles

Adult T-Cell Leukemia/Lymphoma Diagnosed in North American Is Characterized By a Requirement for BCL6 and a Cell Cycle Program Associated with DNA Replication Stress

Free
B. Hilda Ye, Elaine Chung, Xiaoxin Ren, Kith Pradhan, Yanhua Wang, Advaitha Madireddy, Xingxing Zang, Murali Janakiram, R. Alejandro Sica, Amit Verma
Journal: Blood
Blood (2022) 140 (Supplement 1): 8764–8765.
https://doi.org/10.1182/blood-2022-170425
Published: 2022
Journal Articles

Whole-genome landscape of adult T-cell leukemia/lymphoma

Free
Yasunori Kogure, Takuro Kameda, Junji Koya, Makoto Yoshimitsu, Kisato Nosaka, Jun-ichirou Yasunaga, Yoshitaka Imaizumi, Mizuki Watanabe, Yuki Saito, Yuta Ito, Marni B. McClure, Mariko Tabata, Sumito Shingaki, Kota Yoshifuji, Kenichi Chiba, Ai Okada, Nobuyuki Kakiuchi, Yasuhito Nannya, Ayako Kamiunten, Yuki Tahira, Keiichi Akizuki, Masaaki Sekine, Kotaro Shide, Tomonori Hidaka, Yoko Kubuki, Akira Kitanaka, Michihiro Hidaka, Nobuaki Nakano, Atae Utsunomiya, R. Alejandro Sica, Ana Acuna-Villaorduna, Murali Janakiram, Urvi Shah, Juan Carlos Ramos, Tatsuhiro Shibata, Kengo Takeuchi, Akifumi Takaori-Kondo, Yasushi Miyazaki, Masao Matsuoka, Kenji Ishitsuka, Yuichi Shiraishi, Satoru Miyano, Seishi Ogawa, B. Hilda Ye, Kazuya Shimoda, Keisuke Kataoka
Journal: Blood
Blood (2022) 139 (7): 967–982.
https://doi.org/10.1182/blood.2021013568
Published: 2022
Includes: Supplemental data
Journal Articles

Predictors of Central Nervous System (CNS) Involvement in North American Adult T-Cell Leukemia Lymphoma (ATLL) and Their Survival Pattern

Free
Riya Patel, Shafia Rahman, Nishi Shah, Astha Thakkar, Ana Acuna-Villaorduna, Urvi A Shah, Diego Adrianzen Herrera, Alyssa De Castro, Jennat Mustafa, Fariha Khatun, Amanda Lombardo, Latoya Townsend Nugent, Yanhua Wang, Olga Derman, Shira Slasky, Kira Gritsman, Ulrich G. Steidl, Mendel Goldfinger, Noah Kornblum, Aditi Shastri, Ioannis Mantzaris, Lizamarie Bachier-Rodriguez, Ira Braunschweig, Amit Verma, Katharine McNeill, B. Hilda Ye, Murali Janakiram, R. Alejandro Sica
Journal: Blood
Blood (2021) 138 (Supplement 1): 1400.
https://doi.org/10.1182/blood-2021-151447
Published: 2021
Journal Articles

Whole-Genome Analysis of Adult T-Cell Leukemia/Lymphoma

Free
Yasunori Kogure, MD PhD, Takuro Kameda, MD PhD, Junji Koya, PhD MD, Ayako Kamiunten, MD, Kotaro Shide, MD PhD, Tomonori Hidaka, MD, Yoko Kubuki, MD PhD, Makoto Yoshimitsu, MD PhD, Kisato Nosaka, MD PhD, Yoshitaka Imaizumi, MD PhD, Mizuki Watanabe, MD, Yuki Saito, MD, Marni B McClure, MD PhD, Mariko Tabata, MD, Sumito Shingaki, PhD MD, Kota Yoshifuji, MD, Yuichi Shiraishi, PhD, Michihiro Hidaka, MD PhD, Atae Utsunomiya, MD, Urvi A. Shah, MD, Ana Acuna-Villaorduna, MD, Aditi Shastri, MD, R. Alejandro Sica, MD, Murali Janakiram, MD, Juan Carlos Ramos, MD BS, Tatsuhiro Shibata, MD PhD, Akifumi Takaori-Kondo, MD PhD, Yasushi Miyazaki, MD PhD, Masao Matsuoka, MDPhD, Kenji Ishitsuka, MD PhD, Seishi Ogawa, MD PhD, B. Hilda Ye, PhD, Kazuya Shimoda, MD PhD, Keisuke Kataoka, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 29–30.
https://doi.org/10.1182/blood-2020-134360
Published: 2020
Journal Articles

Prognostic Factors for North American Adult T Cell Leukemia Lymphoma: Defining Risk Groups Using a Four-Point Score Prognostic System

Free
Shafia Rahman, MD, Alvaro Alvarez Soto, MD, Lindor Qunaj, MD, Kenny Ye, Kith Pradhan, PhD, Astha Thakkar, MBBS, Zhu Cui, MD, Michal Kasher Meron, Angelica D'Aiello, Amanda Lombardo, PA-C, BS, MS, Jennat Mustafa, PA-C, Fariha Khatun, PA-C, Kailyn Gillick, PA-C, Felisha Joseph, PA-C, Anjali Naik, PA-C, Alyssa De Castro, PharmD, Ulrich G. Steidl, MDPhD, Hao Wang, MS, Xiaoxin Ren, Xingxing Zang, PhD, Olga Derman, MD, Kira Gritsman, MDPhD, Noah Kornblum, MD, Aditi Shastri, MD, Ioannis Mantzaris, MD MS, Mendel Goldfinger, MD, Ira Braunschweig, MD, B. Hilda Ye, PhD, Amit Verma, MBBS, Murali Janakiram, MD, Urvi A Shah, MD, R. Alejandro Sica, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 38–39.
https://doi.org/10.1182/blood-2020-141428
Published: 2020
Journal Articles

Allogeneic Stem Cell Transplantation in a Large Urban Cohort of North-American Adult T-Cell Leukemia/Lymphoma

Free
Astha Thakkar, MBBS, Diego Adrianzen Herrera, MD, Shafia Rahman, MD, Zhu Cui, MD, Angelica D'Aiello, Amanda Lombardo, PA-C, BS, MS, Fariha Khatun, PA-C, Jennat Mustafa, PA-C, Kailyn Gillick, PA-C, Felisha Joseph, PA-C, Anjali Naik, PA-C, Latoya Townsend Nugent, NP, Nicole Chambers, ANP/FNP, Rosmi Mathew, FNP-BC, Michelly Abreu, ANP,MSN, Richard Elkind, PA-C, MS, Henrietta Noicely, RN, MSN, FNP, CNL, Ruby Yusay, BSN, RN, Carlo Palesi, Randin Nelson, MD, Donika Binakaj, BBA, Ulrich G. Steidl, MDPhD, Olga Derman, MD, Kira Gritsman, MDPhD, Noah Kornblum, MD, Ioannis Mantzaris, MD MS, Aditi Shastri, MD, Mendel Goldfinger, MD, Lizamarie Bachier-Rodriguez, MD, B. Hilda Ye, PhD, Amit Verma, MBBS, Ira Braunschweig, MD, Murali Janakiram, R. Alejandro Sica, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 21–22.
https://doi.org/10.1182/blood-2020-140812
Published: 2020