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Salomon Manier
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Journal Articles

A Phase 2/3, multicenter, randomized, open-label study evaluating the efficacy and safety of etentamig and daratumumab compared to daratumumab, lenalidomide, and dexamethasone in frailer transplant-ineligible patients with newly diagnosed multiple myeloma

Free
Salomon Manier, Noemí Puig, Xavier Leleu, Albert Oriol, Cyrille Hulin, Ramon García-Sanz, Jill Corre, Jesus San-Miguel, Thierry Facon, Hans Lee, Peter Forsberg, Kaustav Chatterjee, Anders Svensson, Chetasi Talati, Sunny He, Thomas Doerr, Emma Arriola, Myles Dillon, Jennifer Lin, Linh Nguyen, Fan Wang, María-Victoria Mateos
Journal: Blood
Blood (2025) 146 (Supplement 1): 2288.
https://doi.org/10.1182/blood-2025-2288
Published: 2025
Journal Articles

Relative mortality in elderly frail patients with newly diagnosed multiple myeloma: Ad-hoc analysis of the Phase 3 IFM 2017-03 trial compared to population-based data in France and implications for the functional cure concept

Free
Julie Castiaux, Noemie Bigot, Cyrille Hulin, Magaret Macro, Kamel Laribi, Carla Araujo, Gian Matteo Pica, Cyrille Touzeau, Pascal Godmer, Aurore Perrot, Jean-Yves Mary, Jill Corre, Herve Avet-Loiseau, Philippe Moreau, Xavier Leleu, Thierry Facon, Jerome Lambert, Salomon Manier
Journal: Blood
Blood (2025) 146 (Supplement 1): 498.
https://doi.org/10.1182/blood-2025-498
Published: 2025
Journal Articles

Longitudinal assessments of minimal residual disease in high-risk patients from benefit phase 3 randomized Study of isatuximab plus lenalidomide and dexamethasone with bortezomib (Isa-VRd) versus isard in newly diagnosed transplant ineligible multiple myeloma. (IFM 2020-05)

Free
Anais Schavgoulidze, Jerome Lambert, Arthur Bobin, Salomon Manier, Aurore Perrot, Lionel Karlin, Murielle Roussel, Noemie Bigot, Omar Benbrahim, Olivier Allangba, Philippe Rey, Veronique Dorvaux, Marguerite Vignon, Virginie Roland, Reda Garidi, Jean-Noel Bastie, Marie-Lorraine Chrétien, Sophie Godet, Lydia Montes, Cherel Brieuc, Ikhlef Souhila, Anne Vekkhof, Thomas Chalopin, Bohrane Slama, Laurent Frenzel, Emilie Chalayer, Helene Gardeney, Magaret Macro, Bruno Royer, Stephanie Harel, Olivier Decaux, Bertrand Arnulf, Karim Belhadj Merzoug, Cyrille Touzeau, Mohamad Mohty, Aurelie Gontier, Philippe Moreau, Thierry Facon, Jill Corre, Cyrille Hulin, Xavier Leleu
Journal: Blood
Blood (2025) 146 (Supplement 1): 497.
https://doi.org/10.1182/blood-2025-497
Published: 2025
Journal Articles

First results of the rwe prospective study TEC care (IFM 2023-01) evaluating teclistamab in triple-class exposed relapsed refractory multiple myeloma patients.

Free
Aurore Perrot, Cyrille Hulin, Stephanie Harel, Veronique Vitry, Andrea Pieragostini, Salomon Manier, Carolyne Croizier, Pascal Lenain, Julie Gay, Laurent Frenzel, Thomas Chalopin, Emilie Chalayer, Edmond Chiche, Laure Vincent, Stephane Moreau, Magaret Macro, Lydia Montes, Driss Chaoui, Hélène Demarquette, Jean Marc Schiano De Colella, Cecile Sonntag Mottier, Frederique Orsini Piocelle, Veronique Dorvaux, Karim Belhadj Merzoug, Virginie Roland, Jean Fontan, Olivier Decaux, Cherel Brieuc, Riad Benramdane, Claire Breal, Dony Arthur, Sophie Vernet, Marie Pierres, Marie Odile Petillon, Philippe Moreau, Ariane Boumendil, Cyrille Touzeau
Journal: Blood
Blood (2025) 146 (Supplement 1): 5836.
https://doi.org/10.1182/blood-2025-5836
Published: 2025
Journal Articles

Safety and efficacy of linvoseltamab (LINVO) combined with anti-CD38 monoclonal antibodies (mAbs) daratumumab (DARA) or isatuximab (ISA) in patients (pts) with relapsed/refractory multiple myeloma (RRMM): Initial results from the multicohort, Phase 1b LINKER-MM2 trial

Free
Meletios Dimopoulos, Sosana Delimpasi, Salomon Manier, Jean-Marie Michot, Enrique Ocio, Samuel Rubinstein, Joselle Cook, Maria Del Carmen Martinez Chamorro, Aurora Breazna, Amishi Dhadwal, Yogita Ghodke, Sheila Masinde, Glenn Kroog, Shawn Sarkaria, Albert Oriol
Journal: Blood
Blood (2025) 146 (Supplement 1): 2254.
https://doi.org/10.1182/blood-2025-2254
Published: 2025
Journal Articles

Long-term progression-free survival benefit with ciltacabtagene autoleucel in standard-risk relapsed / refractory multiple myeloma

Free
Luciano Costa, Albert Oriol, Dominik Dytfeld, Salomon Manier, Peter Voorhees, Yi Lin, Myo Htut, Wilfried Roeloffzen, Phoebe Joy Ho, Urvi Shah, Man Zhao, Quanlin Li, Agnes Balogh, Katherine Li, Ana Slaughter, Nina Benachour, Carolina Lonardi, Arnab Ghosh, Huabin Sun, Nikoletta Lendvai, Tamar Lengil, Nitin Patel, Mythili Koneru, Erika Florendo, Octavio Costa, Vrinda Mahajan, Paula Rodriguez-Otero, Christopher Strouse, Keith Stewart, Surbhi Sidana
Journal: Blood
Blood (2025) 146 (Supplement 1): 94.
https://doi.org/10.1182/blood-2025-94
Published: 2025
Journal Articles

Phase 1 study of ktx-1001, a first-in-class oral MMSET/NSD2 inhibitor, demonstrates clinical activity in relapsed/refractory multiple myeloma

Free
Saad Usmani, Pierre Bories, Cristina Gasparetto, David Dingli, Sagar Lonial, David Siegel, Andrew Yee, Cindy Varga, Suzanne Trudel, Laura Rosiñol Dachs, Paula Rodriguez-Otero, Salomon Manier, Jesús Berdeja, Aimaz Afrough, Warren Baker, Seyed Alireza Hasheminasab, Anjan Thakurta, Vinidhra Sridharan, Erin Flynt, Miriam Barnett, Laura Versmee, María-Victoria Mateos, Cyrille Touzeau, Alfred Chung, Vivek Roy, Edward Stadtmauer
Journal: Blood
Blood (2025) 146 (Supplement 1): 250.
https://doi.org/10.1182/blood-2025-250
Published: 2025
Journal Articles

Apixaban pharmacokinetics in newly diagnosed multiple myeloma patients treated in the benefit and isasocut clinical trials: The apixabor/mibapix study

Free
Emilie Chalayer, Elisabeth Daguenet, Arthur Bobin, Thomas Fatrara, Ilhame Bounouara, Stephanie Noel, Karine Garnier, Lionel Karlin, Cyrille Touzeau, Olivier Decaux, Cyrille Hulin, Thomas Chalopin, Magaret Macro, Mamoun Dib, Mourad Tiab, Claire Dingremont, Pascal Godmer, Lydia Montes, Valérie Vidal, Adrienne Labarthe, Emmanuel Fleck, Laure Vincent, Jean-Sébastien Blade, Agathe Waultier-Rascalou, Julie Gay, Murielle Roussel, Frederique Orsini Piocelle, Laurent Frenzel, Philippe Moreau, Salomon Manier, Aurore Perrot, Xavier Leleu, Xavier Delavenne
Journal: Blood
Blood (2025) 146 (Supplement 1): 744.
https://doi.org/10.1182/blood-2025-744
Published: 2025
Journal Articles

Multicenter phase 2 study of subcutaneous isatuximab plus bortezomib , lenalidomide and dexamethasone (Isa Sc-VRd) in transplant ineligible newly diagnosed multiple myeloma: Final analysis of the isasocut study (IFM 2022-05)

Free
Arthur Bobin, Rick Zhang, Mony Morisse, Anais Schavgoulidze, Stéphanie Ragot, Christophe Roul, Thomas Chalopin, Lydia Montes, Mamoun Dib, Mourad Tiab, Frederique Orsini Piocelle, Thorsten Braun, Julie Gay, Carla Araujo, Reza Tabrizi, Laure Vincent, Alberto Santagostino, karine Garnier, Douaa Dhahri, Mohamad Mohty, Magaret Macro, Murielle Roussel, Lionel Karlin, Philippe Moreau, Cyrille Touzeau, Aurore Perrot, Thierry Facon, Cyrille Hulin, Jill Corre, Salomon Manier, Xavier Leleu
Journal: Blood
Blood (2025) 146 (Supplement 1): 2275.
https://doi.org/10.1182/blood-2025-2275
Published: 2025
Journal Articles

Sustained minimal residual disease (sMRD) negativity in transplant ineligible newly diagnosed multiple myeloma treated with isatuximab plus lenalidomide and dexamethasone with bortezomib (Isa-VRd) versus isa-rd: 12-24-month data from the phase 3 benefit trial (IFM 2020-05)

Free
Arthur Bobin, Jerome Lambert, Jill Corre, Salomon Manier, Aurore Perrot, Lionel Karlin, Murielle Roussel, Noemie Bigot, Kamel Laribi, Claire Dingremont, Christophe Roul, Valentine Richez, Clara Mariette, Sophie Rigaudeau, Claire Calmettes, Mamoun Dib, Mourad Tiab, Laure Vincent, Jacques Delaunay, Jean Pierre Marolleau, Pascal Godmer, Anaïs Schavgoulidze, Laurent Frenzel, Ronan Le Calloch, Emilie Chalayer, Helene Gardeney, Magaret Macro, Bruno Royer, Stephanie Harel, Olivier Decaux, Bertrand Arnulf, Karim Belhadj Merzoug, Cyrille Touzeau, Mohamad Mohty, Philippe Moreau, Thierry Facon, Cyrille Hulin, Xavier Leleu
Journal: Blood
Blood (2025) 146 (Supplement 1): 368.
https://doi.org/10.1182/blood-2025-368
Published: 2025
Journal Articles

A phase 2 Study of teclistamab in combination with daratumumab in elderly patients with newly diagnosed multiple myeloma: The IFM2021-01 teclille trial, cohort a

Free
Salomon Manier, Jerome Lambert, Magaret Macro, Thomas Chalopin, Mamoun Dib, Anne Rumpler, Julie Gay, Jean-Noel Bastie, Caroline Jacquet, Cecile Sonntag Mottier, Laure Vincent, Aurore Perrot, Clara Mariette, Lydia Montes, Sophie Rigaudeau, Noemie Bigot, Margaret Doyle, Diptendu Santra, Pavel Smirnov, Claire Albrecht, Cyrille Touzeau, Jill Corre, Philippe Moreau, Herve Avet-Loiseau, Cyrille Hulin, Xavier Leleu, Thierry Facon
Journal: Blood
Blood (2025) 146 (Supplement 1): 367.
https://doi.org/10.1182/blood-2025-367
Published: 2025
Journal Articles

Favorable impact of patient's selection on outcome of Relapsed/Refractory multiple myeloma treated with idecabtagene vicleucel (Ide-cel) chimeric antigen receptor (CAR) T-cell therapy; Experience in french patients (Super-FENIX): An IFM study from the descar-T registry

Free
Bertrand Arnulf, Jerome Lambert, Lionel Karlin, Cyrille Touzeau, Olivier Decaux, Aurore Perrot, Marie-Odile Petillon, Denis Caillot, Salomon Manier, Jean Marc Schiano De Colella, Mohamad Mohty, Laure Vincent, Karim Belhadj Merzoug, Xavier Leleu, Cyrille Hulin, Michael Loschi, Lydia Montes, Thomas Chalopin, Carine Chateleix, Camille Bigenwald, Jean-Richard Eveillard, Yann Guillermin, Fabrice Jardin, Alexis Talbot, Anne Lazareth, Jean-Noel Bastie, Stephanie Harel, Jill Corre, Roch Houot, Niels Moya, Pierre Bories, Titouan Cazaubiel, Noemie Bigot, Thierry Facon, Herve Avet-Loiseau, Benoit Ferment, Philippe Moreau
Journal: Blood
Blood (2025) 146 (Supplement 1): 4076.
https://doi.org/10.1182/blood-2025-4076
Published: 2025
Journal Articles

Real-world outcomes of transplant-ineligible newly diagnosed multiple myeloma patients treated in the United States with contemporary regimens

Free
Salomon Manier, Lauren E. Cain, Quan Chen, Sunny He, Kaustav Chatterjee, Hira Mian
Journal: Blood
Blood (2025) 146 (Supplement 1): 6341.
https://doi.org/10.1182/blood-2025-6341
Published: 2025
Journal Articles

KarMMa-3 subgroup analysis in older patients with relapsed/refractory multiple myeloma treated with idecabtagene vicleucel

Free
Sikander Ailawadhi, Bertrand Arnulf, Krina Patel, Michele Cavo, Ajay Nooka, Salomon Manier, Shinsuke Iida, Sophie Hello, Devender Dhanda, Prachi Ghodke, Martina Raggi, Roland Marion Gallois, Jaclyn Davis, Paula Rodriguez-Otero
Journal: Blood
Blood (2025) 146 (Supplement 1): 2297.
https://doi.org/10.1182/blood-2025-2297
Published: 2025
Journal Articles

High-risk genomic consensus validation for patients with newly diagnosed multiple myeloma using next-generation sequencing

Available to Purchase
Anaïs Schavgoulidze, Aurore Perrot, Xavier Leleu, Titouan Cazaubiel, Marie-Lorraine Chretien, Pierre Feugier, Karim Belhadj, Salomon Manier, Murielle Roussel, Sabine Brechignac, Frederique Orsini Piocelle, Mohamad Mohty, Jean Marc Schiano de Colella, Margaret Macro, Dr, Didier Adiko, Mamoun Dib, Jean Fontan, Carine Motard, Didier Bouscary, Laurent Pascal, Virginie Roland, Francois Lifermann, Jana Armelle Bakala, Lydia Montes, Celine Kennel, Philippe Rey, Valentine Richez, Faiza Keddar, Laurent Frenzel, Claire Calmettes, Carine Chaleteix, Isabelle Plantier, Emilie Chalayer, Anna Schmitt, Christophe Roul, Hélène Demarquette, Chloe Cerutti, Luka Pavageau, Laure Derrier, Hervé Avet-Loiseau, Jill Corre
Journal: Blood
Blood blood.2025029999.
https://doi.org/10.1182/blood.2025029999
Published: 2025
Includes: Supplemental data
Journal Articles

A phase 2 randomized study of modakafusp alfa as a single agent for patients with relapsed/refractory multiple myeloma

Open Access
Clinical Trials & Observations
Sarah A. Holstein, Shebli Atrash, Hira Mian, Meletios A. Dimopoulos, Fredrik Schjesvold, Rakesh Popat, Nishi Shah, Moshe E. Gatt, Christian B. Gocke, Laurent Frenzel, Cyrille Touzeau, Meral Beksac, Salomon Manier, Hila Magen, Patrick Travis, Omar Nadeem, Kaveri Suryanarayan, Cheryl Li, Shuli Li, Allison Nelson, Dasha Cherepanov, Xavier Parot, Dan T. Vogl
Journal: Blood
Blood (2025) 146 (9): 1051–1064.
https://doi.org/10.1182/blood.2024027873
Published: 2025
Includes: Supplemental data
Journal Articles

Isatuximab, carfilzomib, lenalidomide, and dexamethasone induction in newly diagnosed myeloma: analysis of the MIDAS trial

Available to Purchase
Clinical Trials & Observations
Aurore Perrot, Cyrille Touzeau, Jerome Lambert, Cyrille Hulin, Denis Caillot, Lionel Karlin, Bertrand Arnulf, Philippe Rey, Laurent Garderet, Margaret Macro, Martine Escoffre Barbe, Julie Gay, Thomas Chalopin, Romain Gounot, Jean-Marc Schiano, Mourad Tiab, Mohamad Mohty, Frederique Kuhnowski, Jean Fontan, Salomon Manier, Frederique Orsini-Piocelle, Laure Vincent, Sophie Rigaudeau, Xavier Leleu, Benjamin Hebraud, Laurent Flet, Jean-Valere Malfuson, Caroline Jacquet, Driss Chaoui, Nathalie Meuleman, Wajed Abarah, Lydia Montes, Riad Benramdane, Cecile Sonntag, Hacene Zerazhi, Alina Danu, Olivier Allangba, Mamoun Dib, Murielle Roussel, Sophie Cereja, Julien Depaus, Nicolas Branche, Helene Demarquette, Valentine Richez, Brieuc Cherel, Laurent Frenzel, Marie-Christiane Vekemans, Noemie Bigot, Herve Avet-Loiseau, Jill Corre, Philippe Moreau
Journal: Blood
Blood (2025) 146 (1): 52–61.
https://doi.org/10.1182/blood.2024026230
Published: 2025
Journal Articles

Large-scale dependency and drug screens to characterize the therapeutic vulnerabilities of multiple myeloma with 1q+

Available to Purchase
Romanos Sklavenitis-Pistofidis, Elizabeth D. Lightbody, Mairead Reidy, Junko Tsuji, Jean-Baptiste Alberge, Michelle P. Aranha, Daniel Heilpern-Mallory, Harvey G. Roweth, Daisy Huynh, Stephen J. F. Chong, Anna Y. Chung, Jeremy Zhang, Liam Hackett, Nicholas J. Haradhvala, Ting Wu, Nang K. Su, Brianna Berrios, Saveliy Belkin, Ankit K. Dutta, Ryan A. Knudson, Carolyn Brandt, Patricia T. Greipp, Matthew S. Davids, Maria Papaioannou, Gad Getz, Irene M. Ghobrial, Salomon Manier
Journal: Blood
Blood (2025) 146 (1): 89–103.
https://doi.org/10.1182/blood.2024025102
Published: 2025
Includes: Supplemental data
Journal Articles

Efficacy and safety of teclistamab in patients with relapsed/refractory multiple myeloma after BCMA-targeting therapies

Free
Clinical Trials & Observations
Cyrille Touzeau, Amrita Y. Krishnan, Philippe Moreau, Aurore Perrot, Saad Z. Usmani, Salomon Manier, Michele Cavo, Carmen Martinez Chamorro, Ajay K. Nooka, Thomas G. Martin, Lionel Karlin, Xavier Leleu, Nizar J. Bahlis, Britta Besemer, Lixia Pei, Sarah Stein, Shun Xin Wang Lin, Danielle Trancucci, Raluca I. Verona, Suzette Girgis, Xin Miao, Clarissa M. Uhlar, Katherine Chastain, Alfred L. Garfall
Journal: Blood
Blood (2024) 144 (23): 2375–2388.
https://doi.org/10.1182/blood.2023023616
Published: 2024
Includes: Supplemental data
Journal Articles

Ide-cel vs standard regimens in triple-class–exposed relapsed and refractory multiple myeloma: updated KarMMa-3 analyses

Free
Clinical Trials & Observations
Sikander Ailawadhi, Bertrand Arnulf, Krina Patel, Michele Cavo, Ajay K. Nooka, Salomon Manier, Natalie Callander, Luciano J. Costa, Ravi Vij, Nizar J. Bahlis, Philippe Moreau, Scott Solomon, Ingerid Weum Abrahamsen, Rachid Baz, Annemiek Broijl, Christine Chen, Sundar Jagannath, Noopur Raje, Christof Scheid, Michel Delforge, Reuben Benjamin, Thomas Pabst, Shinsuke Iida, Jesús Berdeja, Sergio Giralt, Anna Truppel-Hartmann, Yanping Chen, Xiaobo Zhong, Fan Wu, Julia Piasecki, Laurie Eliason, Devender Dhanda, Jasper Felten, Andrea Caia, Mark Cook, Mihaela Popa McKiver, Paula Rodríguez-Otero
Journal: Blood
Blood (2024) 144 (23): 2389–2401.
https://doi.org/10.1182/blood.2024024582
Published: 2024
Includes: Supplemental data