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Journal Articles

Nilotinib with or without cytarabine for Philadelphia-positive acute lymphoblastic leukemia

Clinical Trials & Observations
Yves Chalandon, Philippe Rousselot, Sylvie Chevret, Jean-Michel Cayuela, Rathana Kim, Françoise Huguet, Patrice Chevallier, Carlos Graux, Anne Thiebaut-Bertrand, Sylvain Chantepie, Xavier Thomas, Laure Vincent, Céline Berthon, Yosr Hicheri, Emmanuel Raffoux, Martine Escoffre-Barbe, Isabelle Plantier, Magalie Joris, Pascal Turlure, Florence Pasquier, Amine Belhabri, Gabrielle Roth Guepin, Sabine Blum, Michael Gregor, Marina Lafage-Pochitaloff, Julie Quessada, Véronique Lhéritier, Emmanuelle Clappier, Nicolas Boissel, Hervé Dombret
Journal: Blood
Blood (2024) 143 (23): 2363–2372.
https://doi.org/10.1182/blood.2023023502
Published: 2024
Includes: Supplemental data
Journal Articles

Ixazomib, Pomalidomide and Dexamethasone (IxPd) in Relapsed or Refractory Multiple Myeloma (RRMM) Characterized with High-Risk Cytogenetics. IFM 2014-01

Arthur Bobin, Salomon Manier, Joe De Keizer, Cyrille Hulin, Lionel Karlin, Denis Caillot, Clara Mariette, Carla Araujo, Bertrand Arnulf, Benoit Bareau, Karim Belhadj Merzoug, Lotfi Benboubker, Thorsten Braun, Claire Calmettes, Olivier Decaux, Mamoun Dib, Helene Demarquette, Pierre Feugier, Cécile Sonntag, Arnaud Jaccard, Pascal Lenain, Margaret Macro, Valentine Richez, Mourad Tiab, Laure Vincent, Hacene Zerazhi, Marie-Odile Petillon, Cyrille Touzeau, Aurore Perrot, Philippe Moreau, Thierry Facon, Herve Avet Loiseau, Xavier Leleu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6724.
https://doi.org/10.1182/blood-2023-186599
Published: 2023
Journal Articles

Integrative Multi-Omics Analysis of Tumor-Immune Microenvironment in Multiple Myeloma: Novel Insights and Therapeutic Implications

Elina Alaterre, Nicolas Robert, Guilhem Requirand, Amélie Machura, Hugues De Boussac, Laure Vincent, Charles Herbaux, Angélique Bruyer, Jerome Moreaux
Journal: Blood
Blood (2023) 142 (Supplement 1): 4743.
https://doi.org/10.1182/blood-2023-181767
Published: 2023
Journal Articles

Epigenetic Modifiers MMSET and EZH2 Physically Interact and Cooperate to Support Multiple Myeloma Pathophysiology

Emmanuel Varlet, Elina Alaterre, Morgane Thomas, Hugues De Boussac, Laure Vincent, Guillaume Cartron, Charles Herbaux, Caroline Bret, Laurie Herviou, Anne Marie Martinez, Christophe Hirtz, Aurore Attina, Jerome Vialaret, Giacomo Cavalli, Jerome Moreaux, Sara Ovejero
Journal: Blood
Blood (2023) 142 (Supplement 1): 1964.
https://doi.org/10.1182/blood-2023-181018
Published: 2023
Journal Articles

Characterization of a New Metabolic Score Correlated with CD38 Cell-Surface Expression and Response to Daratumumab Treatment in Multiple Myeloma

Alizée Steer, Elina Alaterre, Djamila Chamlal, Emmanuel Varlet, Amélie Machura, Alboukadel Kassambara, Guilhem Requirand, Nicolas Robert, Laure Vincent, Charles Herbaux, Hugues De Boussac, Angélique Bruyer, Jerome Moreaux
Journal: Blood
Blood (2023) 142 (Supplement 1): 1949.
https://doi.org/10.1182/blood-2023-180877
Published: 2023
Journal Articles

French Early Nationwide Idecabtagene Vicleucel (Ide-Cel) Chimeric Antigen Receptor (CAR) T-Cell Therapy Experience in Patients with Relapsed/Refractory Multiple Myeloma (FENIX): Update of the IFM Study from the Descar-T Registry

Sarah Cayla, Benoit Ferment, Noemie Bigot, Denis Caillot, Ingrid Lafon, Lionel Karlin, Anne Lazareth, Cyrille Touzeau, Xavier Leleu, Niels Moya, Stephanie Harel, Aurore Perrot, Pierre Bories, Laure Vincent, Sylvain Lamure, Mohamad Mohty, Florent Malard, Salomon Manier, Ibrahim Yakoub-Agha, Anne-Marie Stoppa, Gabriel Brisou, Olivier Decaux, Roch Houot, Steven Le Gouill, Jerome Lambert, Thierry Facon, Herve Avet Loiseau, Philippe Moreau, Bertrand Arnulf
Journal: Blood
Blood (2023) 142 (Supplement 1): 2139.
https://doi.org/10.1182/blood-2023-188655
Published: 2023
Journal Articles

Multicenter Open Label Phase 2 Study of Quadruplet-Based Regimen Iskpd (isatuximab plus pomalidomide and dexamethasone with carfilzomib) in Early Relapsed or Refractory Multiple Myeloma - IFM2018-03

Arthur Bobin, Jerome Lambert, Stéfanie Ragot, Aurore Perrot, Salomon Manier, Lionel Karlin, Denis Caillot, Lotfi Benboubker, Thomas Chalopin, Carla Araujo, Jean Fontan, Thorsten Braun, Clara Mariette, Elodie Scherman, Olivier Decaux, jean Sebastien Blade, Faiza Keddar, Christophe Roul, Mamoun Dib, Jill Corre, Frederique Orsini Piocelle, Laure Vincent, Cyrille Touzeau, Philippe Moreau, Herve Avet Loiseau, Xavier Leleu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6742.
https://doi.org/10.1182/blood-2023-185792
Published: 2023
Journal Articles

Lipid-Mediated Modulation of DNA Damage Signaling As a Prognostic and Therapeutic Strategy Against Multiple Myeloma

Elvira Garcia De Paco, Caroline Soulet, Guilhem Requirand, Nicolas Robert, Guillaume Cartron, Laure Vincent, Charles Herbaux, Maria Moriel-Carretero, Jerome Moreaux
Journal: Blood
Blood (2023) 142 (Supplement 1): 3322.
https://doi.org/10.1182/blood-2023-181039
Published: 2023
Journal Articles

Real-World Outcomes of Newly Diagnosed Multiple Myeloma (NDMM) Patients Treated before the Anti-CD38 Antibodies Era in France, the Emmy Cohort 2017 to 2020

Laure Vincent, Olivier Decaux, Aurore Perrot, Bruno Royer, Thomas Chalopin, Arthur Bobin, Margaret Macro, Denis Caillot, Lionel Karlin, Caroline Jacquet, Cécile Sonntag, Mohamad Mohty, Laurent Frenzel, Arnaud Jaccard, Laurence Sanhes, Driss Chaoui, Nathalie Texier, Chanaz Louni, Zakaria Maarouf, Herve Avet Loiseau, Cyrille Hulin, Karim Belhadj Merzoug
Journal: Blood
Blood (2023) 142 (Supplement 1): 3355.
https://doi.org/10.1182/blood-2023-173845
Published: 2023
Journal Articles

Translation Inhibition through eIF4A1 Targeting in Multiple Myeloma Is a Promising Therapeutic Strategy

Laure Dutrieux, Elle Loughran, Armelle Choquet, Hélène Herault, Antoine Guillemin, Nicolas Robert, Guilhem Requirand, Guillaume Cartron, Laure Vincent, Charles Herbaux, Eric Rivals, Alexandre David, Jerome Moreaux
Journal: Blood
Blood (2023) 142 (Supplement 1): 1924.
https://doi.org/10.1182/blood-2023-184749
Published: 2023
Journal Articles

Long Term Outcomes and Renal Response Following Autologous Stem Cell Transplantation for Light Chain Deposition Disease:a Retrospective Study on Behalf of the Cmwp of the EBMT

Laurent Garderet, Luuk Gras, Sr., Linda Koster, Montserrat Rovira, Laure Vincent, Guido Kobbe, Srinivas Pillai, Dries Deeren, Martin Kaufmann, Jurgen Kuball, Hakan Ozdogu, Maria Jesús Pascual, Jakob R. Passweg, Adam Rye, Urpu Salmenniemi, John Snowden, Thomas Stauffer Larsen, Xavier Leleu, Lauris Gastaud, Joanna Drozd-Sokolowska, Kavita Raj, Meral Beksac, Stefan Schonland, Patrick John Hayden, Donal P McLornan
Journal: Blood
Blood (2023) 142 (Supplement 1): 3403.
https://doi.org/10.1182/blood-2023-184367
Published: 2023
Journal Articles

Multicenter Open Label Phase 3 Benefit Study of Isatuximab Plus Lenalidomide and Dexamethasone with/without Bortezomib in the Treatment of Newly Diagnosed Non-Frail Transplant Ineligible Multiple Myeloma Elderly Patients. IFM2020-05

Arthur Bobin, Cyrille Hulin, Jerome Lambert, Aurore Perrot, Salomon Manier, Lydia Montes, Arnaud Jaccard, Lionel Karlin, Pascal Godmer, Denis Caillot, Thomas Chalopin, Christophe Roul, Clara Mariette, Sophie Rigaudeau, Jacques Delaunay, Claire Dingremont, Alberto Santagostino, Mamoun Dib, Margaret Macro, Mourad Tiab, Kamel Laribi, Emmanuelle Bourgeois Petit, Claire Calmettes, Frederique Orsini Piocelle, Benoit Bareau, Reza Tabrizi, Laure Vincent, Mohamad Mohty, Cyrille Touzeau, Jill Corre, Philippe Moreau, Thierry Facon, Herve Avet Loiseau, Xavier Leleu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6741.
https://doi.org/10.1182/blood-2023-185699
Published: 2023
Journal Articles

Dexaml-02 : A Phase II Study of Dexamethasone Added to Induction and Postremission Therapy in Older Patients with Newly Diagnosed AML. a French Innovative Leukemia Organization (FILO) Study

Christian Recher, Sarah Bertoli, Pierre Peterlin, Romain Guieze, Yohan Desbrosses, Yosr Hicheri, Omar Benbrahim, Martin Carre, Hunault-Berger Mathilde, Anne Banos, Marc Bernard, Emmanuel Gyan, Alain Saad, Safia Chebrek, Gabrielle Roth Guepin, Veronique Dorvaux, Laurence Sanhes, Maria Pilar Gallego Hernanz, Carole Exbrayat, Laure Vincent, Chantal Himberlin, Laetitia Largeaud, Eric Delabesse, Francois Vergez, Norbert Vey, Ariane C Mineur, Célestine Simand, Isabelle Luquet, Arnaud Pigneux
Journal: Blood
Blood (2022) 140 (Supplement 1): 6149–6151.
https://doi.org/10.1182/blood-2022-158665
Published: 2022
Journal Articles

Targeting Iron Homeostasis As a Therapeutic Strategy in Multiple Myeloma

Sara ovejero-Merino, Julie Devin, Tatiana Cañeque, Laura Alibert, Guilhem Requirand, Nicolas Robert, Alizée Steer, Amelie Machura, Christophe Hirtz, Angélique Bruyer, Laure Vincent, Guillaume Cartron, Charles Herbaux, Raphael Rodriguez, Caroline Bret, Jerome Moreaux
Journal: Blood
Blood (2022) 140 (Supplement 1): 9980–9981.
https://doi.org/10.1182/blood-2022-163252
Published: 2022
Journal Articles

Multicenter Open Label Phase 2 Study of Isatuximab Plus Pomalidomide and Dexamethasone with Carfilzomib in Relapsed or Refractory Multiple Myeloma. Iskpd - IFM2018-03

Arthur Bobin, Jerome Lambert, Stéphanie Ragot, Aurore Perrot, Salomon Manier, Lionel Karlin, Denis Caillot, Cyrille Hulin, Lotfi Benboubker, Carla Araujo, Jean Fontan, Thorsten Braun, Clara Mariette, Elodie Scherman, Olivier Decaux, jean Sebastien Blade, Faida Keddar, Christophe Roul, Mamoun Dib, Jill Corre, Frederique Orsini, Laure Vincent, Mohamad Mohty, Cyrille Touzeau, Philippe Moreau, Herve Avet Loiseau, Xavier Leleu
Journal: Blood
Blood (2022) 140 (Supplement 1): 4452–4453.
https://doi.org/10.1182/blood-2022-166870
Published: 2022
Journal Articles

Multicenter Open Label Phase 3 Study of Isatuximab Plus Lenalidomide and Dexamethasone with/without Bortezomib in the Treatment of Newly Diagnosed Non-Frail Transplant Ineligible Multiple Myeloma Elderly Patients (≥ 65; < 80 Years). IFM2020-05/Benefit

Arthur Bobin, Jerome Lambert, Aurore Perrot, Salomon Manier, Lydia Montes, Arnaud Jaccard, Lionel Karlin, Pascal Godmer, Denis Caillot, Cyrille Hulin, Thomas Chalopin, Christophe Roul, Clara Mariette, Sophie Rigaudeau, Claire Dingremont, Alberto Santagostino, Mamoun Dib, Margaret Macro, Mourad Tiab, Kamel Laribi, Emmanuelle Bourgeois-Petit, Claire Calmettes, Frederique Orsini, Reza Tabrizi, Laure Vincent, Mohamad Mohty, Cyrille Touzeau, Jill Corre, Philippe Moreau, Thierry Facon, Herve Avet Loiseau, Xavier Leleu
Journal: Blood
Blood (2022) 140 (Supplement 1): 4423–4425.
https://doi.org/10.1182/blood-2022-168742
Published: 2022
Journal Articles

Retreatment of Patients with Anti CD38-Based Combinations in Multiple Myeloma in Real-Life: Results from the Emmy Cohort Study

Cyrille Hulin, Aurore Perrot, Margaret Macro, Anne Vekhoff, Xavier Leleu, Lionel Karlin, Salomon Manier, Laure Vincent, Abderrazak El Yamani, Wajed Abarah, Régis Kaphan, Charles Zarnitsky, Daniel Re, Laure Christophe, Olivier Fitoussi, Nathalie Texier, Raphael Germain, Marion Willaime, Olivier Decaux
Journal: Blood
Blood (2022) 140 (Supplement 1): 7133–7135.
https://doi.org/10.1182/blood-2022-159424
Published: 2022
Journal Articles

Effectiveness and Safety of Ixazomib in Combination with Lenalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma in a Real-Life Population in France: The Remix Study

Laure Vincent, Anne Charvet-Rumpler, Lotfi Benboubker, Claire Calmettes, Anne-Marie Stoppa, Kamel Laribi, Lauriane Clement Filliatre, Fressia Honeyman, Richez Valentine, Cyrille Hulin, Frédéric Maloisel, Margaret Macro, Lionel Karlin, Vanessa Barué, Christos Chouaid, Hacène Zerazhi, Xavier Leleu
Journal: Blood
Blood (2022) 140 (Supplement 1): 4312–4314.
https://doi.org/10.1182/blood-2022-157942
Published: 2022
Journal Articles

EZH2 Targeting Induces CD38 Upregulation and Response to Anti-CD38 Antibodies in Multiple Myeloma

Djamila Chemlal, Emmanuel Varlet, Amelie Machura, Guilhem Requirand, Nicolas Robert, Elina Alaterre, Laure Vincent, Charles Herbaux, Giacomo Cavalli, Angélique Bruyer, Hugues De Boussac, Jerome Moreaux
Journal: Blood
Blood (2022) 140 (Supplement 1): 4220–4221.
https://doi.org/10.1182/blood-2022-163261
Published: 2022
Journal Articles

French Early Nationwide Idecabtagene Vicleucel (Ide-Cel) Chimeric Antigen Receptor (CAR) T-Cell Therapy Experience in Patients with Relapsed/Refractory Multiple Myeloma (FENIX): An IFM Study from the Descar-T Registry

Benoit Ferment, Jérôme Lambert, Denis Caillot, Ingrid Lafon, Lionel Karlin, Anne Lazareth, Cyrille Touzeau, Xavier Leleu, Niels Moya, Stephanie Harel, Aurore Perrot, Pierre Bories, Laure Vincent, Sylvain Lamure, Mohamad Mohty, Florent Malard, Salomon Manier, Ibrahim Yakoub-Agha, Anne-Marie Stoppa, Gabriel Brisou, Olivier Decaux, Roch Houot, Steven Le Gouill, Thierry Facon, Hervé Avet-Loiseau, Philippe Moreau, Bertrand Arnulf
Journal: Blood
Blood (2022) 140 (Supplement 1): 4668–4670.
https://doi.org/10.1182/blood-2022-162682
Published: 2022