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Journal Articles

NGS-based stratification refines the risk stratification in T-ALL and identifies a very-high-risk subgroup of patients

Clinical Trials & Observations
Mathieu Simonin, Loïc Vasseur, Etienne Lengliné, Ludovic Lhermitte, Aurélie Cabannes-Hamy, Marie Balsat, Aline Schmidt, Marie-Emilie Dourthe, Aurore Touzart, Carlos Graux, Nathalie Grardel, Jean-Michel Cayuela, Isabelle Arnoux, Virginie Gandemer, Françoise Huguet, Stéphane Ducassou, Véronique Lhéritier, Yves Chalandon, Norbert Ifrah, Hervé Dombret, Elizabeth Macintyre, Arnaud Petit, Philippe Rousselot, Jérôme Lambert, André Baruchel, Nicolas Boissel, Vahid Asnafi
Journal: Blood
Blood (2024) 144 (15): 1570–1580.
https://doi.org/10.1182/blood.2023023754
Published: 2024
Includes: Supplemental data
Journal Articles

What clinicians should know about surrogate end points in hematologic malignancies

Clinical Trials & Observations
Côme Bommier, Matthew John Maurer, Jerome Lambert
Journal: Blood
Blood (2024) 144 (1): 11–20.
https://doi.org/10.1182/blood.2023022269
Published: 2024
Includes: Supplemental data
Journal Articles

Early complete response as a validated surrogate marker in extranodal marginal zone lymphoma systemic therapy

Clinical Trials & Observations
Côme Bommier, Emanuele Zucca, Sylvie Chevret, Annarita Conconi, Grzegorz Nowakowski, Matthew J. Maurer, James R. Cerhan, Catherine Thieblemont, Jérôme Lambert
Journal: Blood
Blood (2024) 143 (5): 422–428.
https://doi.org/10.1182/blood.2023020984
Published: 2024
Includes: Supplemental data
Journal Articles

NGS-Based Stratification Refines the Risk Stratification in T-ALL and Identifies a Very High-Risk Subgroup of Patients

Mathieu Simonin, Loïc Vasseur, Etienne Lengline, Ludovic Lhermitte, Aurelie Cabannes-Hamy, Marie Balsat, Aline Schmidt, Marie Emilie Dourthe, Aurore Touzart, Carlos Graux, Nathalie Grardel, Jean-Michel Cayuela, Isabelle Arnoux, Virginie Gandemer, Françoise Huguet, Stephane Ducassou, Véronique Lhéritier, Yves Chalandon, Norbert Ifrah, Herve Dombret, Elizabeth A. Macintyre, Arnaud Petit, Philippe Rousselot, Jerome Lambert, André Baruchel, Nicolas Boissel, Vahid Asnafi
Journal: Blood
Blood (2023) 142 (Supplement 1): 844.
https://doi.org/10.1182/blood-2023-179298
Published: 2023
Journal Articles

French Early Nationwide Idecabtagene Vicleucel (Ide-Cel) Chimeric Antigen Receptor (CAR) T-Cell Therapy Experience in Patients with Relapsed/Refractory Multiple Myeloma (FENIX): Update of the IFM Study from the Descar-T Registry

Sarah Cayla, Benoit Ferment, Noemie Bigot, Denis Caillot, Ingrid Lafon, Lionel Karlin, Anne Lazareth, Cyrille Touzeau, Xavier Leleu, Niels Moya, Stephanie Harel, Aurore Perrot, Pierre Bories, Laure Vincent, Sylvain Lamure, Mohamad Mohty, Florent Malard, Salomon Manier, Ibrahim Yakoub-Agha, Anne-Marie Stoppa, Gabriel Brisou, Olivier Decaux, Roch Houot, Steven Le Gouill, Jerome Lambert, Thierry Facon, Herve Avet Loiseau, Philippe Moreau, Bertrand Arnulf
Journal: Blood
Blood (2023) 142 (Supplement 1): 2139.
https://doi.org/10.1182/blood-2023-188655
Published: 2023
Journal Articles

Multicenter Open Label Phase 2 Study of Quadruplet-Based Regimen Iskpd (isatuximab plus pomalidomide and dexamethasone with carfilzomib) in Early Relapsed or Refractory Multiple Myeloma - IFM2018-03

Arthur Bobin, Jerome Lambert, Stéfanie Ragot, Aurore Perrot, Salomon Manier, Lionel Karlin, Denis Caillot, Lotfi Benboubker, Thomas Chalopin, Carla Araujo, Jean Fontan, Thorsten Braun, Clara Mariette, Elodie Scherman, Olivier Decaux, jean Sebastien Blade, Faiza Keddar, Christophe Roul, Mamoun Dib, Jill Corre, Frederique Orsini Piocelle, Laure Vincent, Cyrille Touzeau, Philippe Moreau, Herve Avet Loiseau, Xavier Leleu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6742.
https://doi.org/10.1182/blood-2023-185792
Published: 2023
Journal Articles

Multicenter Open Label Phase 3 Benefit Study of Isatuximab Plus Lenalidomide and Dexamethasone with/without Bortezomib in the Treatment of Newly Diagnosed Non-Frail Transplant Ineligible Multiple Myeloma Elderly Patients. IFM2020-05

Arthur Bobin, Cyrille Hulin, Jerome Lambert, Aurore Perrot, Salomon Manier, Lydia Montes, Arnaud Jaccard, Lionel Karlin, Pascal Godmer, Denis Caillot, Thomas Chalopin, Christophe Roul, Clara Mariette, Sophie Rigaudeau, Jacques Delaunay, Claire Dingremont, Alberto Santagostino, Mamoun Dib, Margaret Macro, Mourad Tiab, Kamel Laribi, Emmanuelle Bourgeois Petit, Claire Calmettes, Frederique Orsini Piocelle, Benoit Bareau, Reza Tabrizi, Laure Vincent, Mohamad Mohty, Cyrille Touzeau, Jill Corre, Philippe Moreau, Thierry Facon, Herve Avet Loiseau, Xavier Leleu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6741.
https://doi.org/10.1182/blood-2023-185699
Published: 2023
Journal Articles

LSC17 Score Is Complementary with Minimal Residual Disease to Stratify NPM1 -Mutated Acute Myeloid Leukemia: An ALFA Study

Loïc Vasseur, Laurène Fenwarth, Xavier Thomas, Jérôme Lambert, Stéphane de Botton, Martin Figeac, Céline Villenet, Pierre-Yves Dumas, Christian Recher, Céline Berthon, Emilie Lemasle, Delphine Lebon, Juliette Lambert, Christine Terré, Karine Celli-Lebras, Hervé Dombret, Claude Preudhomme, Meyling Cheok, Raphael Itzykson, Nicolas Duployez
Journal: Blood
Blood (2022) 140 (Supplement 1): 6303–6305.
https://doi.org/10.1182/blood-2022-163348
Published: 2022
Journal Articles

Time to Complete Response within 24 Months As a Good Surrogate Marker of 8 Year-Progression Free Survival in Extranodal Marginal Zone Lymphoma

Côme Bommier, Annarita Conconi, Emanuele Zucca, Grzegorz S. Nowakowski, James R. Cerhan, Catherine Thieblemont, Jérôme Lambert
Journal: Blood
Blood (2022) 140 (Supplement 1): 3583–3584.
https://doi.org/10.1182/blood-2022-169805
Published: 2022
Journal Articles

Multicenter Open Label Phase 2 Study of Isatuximab Plus Pomalidomide and Dexamethasone with Carfilzomib in Relapsed or Refractory Multiple Myeloma. Iskpd - IFM2018-03

Arthur Bobin, Jerome Lambert, Stéphanie Ragot, Aurore Perrot, Salomon Manier, Lionel Karlin, Denis Caillot, Cyrille Hulin, Lotfi Benboubker, Carla Araujo, Jean Fontan, Thorsten Braun, Clara Mariette, Elodie Scherman, Olivier Decaux, jean Sebastien Blade, Faida Keddar, Christophe Roul, Mamoun Dib, Jill Corre, Frederique Orsini, Laure Vincent, Mohamad Mohty, Cyrille Touzeau, Philippe Moreau, Herve Avet Loiseau, Xavier Leleu
Journal: Blood
Blood (2022) 140 (Supplement 1): 4452–4453.
https://doi.org/10.1182/blood-2022-166870
Published: 2022
Journal Articles

Multicenter Open Label Phase 3 Study of Isatuximab Plus Lenalidomide and Dexamethasone with/without Bortezomib in the Treatment of Newly Diagnosed Non-Frail Transplant Ineligible Multiple Myeloma Elderly Patients (≥ 65; < 80 Years). IFM2020-05/Benefit

Arthur Bobin, Jerome Lambert, Aurore Perrot, Salomon Manier, Lydia Montes, Arnaud Jaccard, Lionel Karlin, Pascal Godmer, Denis Caillot, Cyrille Hulin, Thomas Chalopin, Christophe Roul, Clara Mariette, Sophie Rigaudeau, Claire Dingremont, Alberto Santagostino, Mamoun Dib, Margaret Macro, Mourad Tiab, Kamel Laribi, Emmanuelle Bourgeois-Petit, Claire Calmettes, Frederique Orsini, Reza Tabrizi, Laure Vincent, Mohamad Mohty, Cyrille Touzeau, Jill Corre, Philippe Moreau, Thierry Facon, Herve Avet Loiseau, Xavier Leleu
Journal: Blood
Blood (2022) 140 (Supplement 1): 4423–4425.
https://doi.org/10.1182/blood-2022-168742
Published: 2022
Journal Articles

Persistence of Mutations in Complete Remission Including DNMT3A , TET2 and ASXL1 Mutations Is Associated with Worse Prognosis in Patients with Acute Myeloid Leukemia Treated in ALFA 0702 Study

Pierre Hirsch, Jérôme Lambert, Maxime Bucci, Caroline Deswarte, Juliette Lambert, Laurène Fenwarth, Herve Dombret, Nicolas Duployez, Claude Preudhomme, Raphael Itzykson, Francois Delhommeau
Journal: Blood
Blood (2022) 140 (Supplement 1): 549–550.
https://doi.org/10.1182/blood-2022-166713
Published: 2022
Journal Articles

A Dexamethasone Sparing-Regimen with Daratumumab and Lenalidomide in Frail Patients with Newly-Diagnosed Multiple Myeloma: Efficacy and Safety Analysis of the Phase 3 IFM2017-03 Trial

Salomon Manier, Jill Corre, Cyrille Hulin, Kamel Laribi, Carla Araujo, Gian-Matteo Pica, Cyrille Touzeau, Pascal Godmer, Bohrane Slama, Lionel Karlin, Frederique Orsini-Piocelle, Mamoun Dib, Margaret Macro, Laurence Sanhes, Aurore Perrot, Jean Yves Mary, Jerome Lambert, Herve Avet-Loiseau, Philippe Moreau, Xavier Leleu, Thierry Facon
Journal: Blood
Blood (2022) 140 (Supplement 1): 1369–1370.
https://doi.org/10.1182/blood-2022-159933
Published: 2022
Journal Articles

French Early Nationwide Idecabtagene Vicleucel (Ide-Cel) Chimeric Antigen Receptor (CAR) T-Cell Therapy Experience in Patients with Relapsed/Refractory Multiple Myeloma (FENIX): An IFM Study from the Descar-T Registry

Benoit Ferment, Jérôme Lambert, Denis Caillot, Ingrid Lafon, Lionel Karlin, Anne Lazareth, Cyrille Touzeau, Xavier Leleu, Niels Moya, Stephanie Harel, Aurore Perrot, Pierre Bories, Laure Vincent, Sylvain Lamure, Mohamad Mohty, Florent Malard, Salomon Manier, Ibrahim Yakoub-Agha, Anne-Marie Stoppa, Gabriel Brisou, Olivier Decaux, Roch Houot, Steven Le Gouill, Thierry Facon, Hervé Avet-Loiseau, Philippe Moreau, Bertrand Arnulf
Journal: Blood
Blood (2022) 140 (Supplement 1): 4668–4670.
https://doi.org/10.1182/blood-2022-162682
Published: 2022
Journal Articles

Low Non Relapse Mortality and Good Hematological Response after Autologous Hematopoietic Stem Cell Transplantation in Multiple Myeloma Patients with Renal Insufficiency at Transplant: A Prospective Société Francaise De Greffe De Moelle-Thérapie Cellulaire Observational Study

Laurent Garderet, Hafida Ouldjeriouat, Mohamed-Amine Bekadja, Elisabeth Daguenet, Laure Vincent, Damien Roos Weil, Marguerite Vignon, Mohamad Mohty, Julie Abraham, Martine Escoffre-Barbe, Bruno Lioure, redhouane Ahmed Nacer, Denis Caillot, Clara Mariette, Lionel Karlin, Pierre Morel, Lila Gilis, Emanuelle Leray, Anaise Blouet, Nicole Raus, Marie Robin, jean Jacques Boffa, Pierre Ronco, Marie Thérèse Rubio, Jerome Lambert, Jérôme Cornillon
Journal: Blood
Blood (2022) 140 (Supplement 1): 7219–7221.
https://doi.org/10.1182/blood-2022-165913
Published: 2022
Journal Articles

Replacing the Anthracycline By Gemtuzumab Ozogamicin in Older Patients with De Novo Standard-Risk Acute Myeloid Leukemia Treated Intensively - Results of the Randomized ALFA1401-Mylofrance 4 Study

Juliette Lambert, Jérôme Lambert, Emilie Lemasle, Magalie Joris, Sylvain Chantepie, Cecile Pautas, Xavier Thomas, Jean Valere Malfuson, Lauris Gastaud, Denis Caillot, Emmanuelle Tavernier, Pascal Turlure, Diana Carp, Celine Berthon, Olivier Legrand, Ambroise Marçais, Iona Vaida, Sarah Barbieux, Philippe Rousselot, Claude Gardin, Christine Terré, Nicolas Duployez, Claude Preudhomme, Karine Celli-Lebras, Sylvie Castaigne, Herve Dombret
Journal: Blood
Blood (2021) 138 (Supplement 1): 31.
https://doi.org/10.1182/blood-2021-145152
Published: 2021
Journal Articles

Daratumumab (DARA) with Bortezomib, Thalidomide, and Dexamethasone (VTd) in Transplant-Eligible Patients (Pts) with Newly Diagnosed Multiple Myeloma (NDMM): Analysis of Minimal Residual Disease (MRD) Negativity in Cassiopeia Part 1 and Part 2

Herve Avet Loiseau, Pieter Sonneveld, Philippe Moreau, Fritz Offner, Vincent H.J. van der Velden, Denis Caillot, Cyrille Hulin, Bertrand Arnulf, Jill Corre, Mohamad Mohty, Lionel Karlin, Jérôme Lambert, Margaret Macro, Aurore Perrot, Mark-David Levin, Saskia K. Klein, Anne-Marie Stoppa, Michel Delforge, Sonja Zweegman, Kon-Siong Jie, Niels W.C.J. Van De Donk, Maria Krevvata, Fabio Rigat, Shiyi Yang, Veronique Vanquickelberghe, Carla de Boer, Tobias Kampfenkel, Jessica Vermeulen, Soraya Wuillème, Annemiek Broyl, Marie C Bene
Journal: Blood
Blood (2021) 138 (Supplement 1): 82.
https://doi.org/10.1182/blood-2021-147897
Published: 2021
Journal Articles

A Systematic Review and a Survey Both Reveal Wide Heterogeneity across Trials and Investigators on Time-to-Event Endpoints Definitions in Marginal Zone Lymphoma

Côme Bommier, Emanuele Zucca, Catherine Thieblemont, Jérôme Lambert
Journal: Blood
Blood (2021) 138 (Supplement 1): 4502.
https://doi.org/10.1182/blood-2021-150603
Published: 2021
Journal Articles

Eltrombopag in Chronic Myelomonocytic Leukemia (CMML) with Severe Thrombocytopenia: Final Results of a Multicenter Phase II Study

Florence Rabian, MD, Jérôme Lambert, Daniela Barbieri, Berengere Gruson, MD, Sylvain Thepot, MD, Thorsten Braun, MD PhD, Norbert Vey, MD, Jacques Delaunay, MD, Laurence Legros, PhD MD, Julie Lejeune, Anouk Walter-petrich, Rosa Sapena, Nathalie Droin, PhD, Fatiha Chermat, Francoise Porteu, Daniel Lusina, Lionel Ades, MDPhD, Eric Solary, MD PhD, Pierre Fenaux, MDPhD, Raphael Itzykson, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15–16.
https://doi.org/10.1182/blood-2020-137469
Published: 2020
Journal Articles

Evaluation of the Prognostic Value of Positron Emission Tomography-Computed Tomography (PET-CT) at Diagnosis and Follow-up in Transplant-Eligible Newly Diagnosed Multiple Myeloma (TE NDMM) Patients Treated in the Phase 3 Cassiopeia Study: Results of the Cassiopet Companion Study

Philippe Moreau, MD, Sonja Zweegman, Aurore Perrot, MD PhD, Cyrille Hulin, MD, Denis Caillot, MD, Thierry Facon, MD, Xavier Leleu, MD PhD, Karim Belhadj, Lionel Karlin, MD, Lotfi Benboubker, MD, Mark-David Levin, MD PhD, Monique C. Minnema, MD PhD, Bastien Jamet, Caroline Bodet-Milin, Pieter Sonneveld, Jérôme Lambert, Lixia Pei, Carla de Boer, Jessica Vermeulen, MD PhD, Tobias Kampfenkel, MD, Francoise Kraeber-Bodere
Journal: Blood
Blood (2019) 134 (Supplement_1): 692.
https://doi.org/10.1182/blood-2019-123143
Published: 2019