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Jeremy Zhang
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Journal Articles

JAK1/2 inhibition with ruxolitinb potentiates ex vivo activity of epcoritamab  in primary CLL cells

Free
Xiao Lyu, Stephanie Chamberlain, Jeremy Zhang, Jing Wang, Nathalie Javidi-Sharifi, Matthew S Davids
Journal: Blood
Blood (2025) 146 (Supplement 1): 2106.
https://doi.org/10.1182/blood-2025-2106
Published: 2025
Journal Articles

CD47-blockade induces programmed necroptosis and complements the effects of BCL-2 inhibition in lymphoid malignancies

Free
Stephen Chong, Rebecca Valentin, Jing Wang, Fen Zhu, Praful Gokhale, Benjamin Eschle, Filip Garbicz, Tomasz Sewastianik, Johany Penailillo, Jeremy Zhang, Liam Hackett, Mary Collins, Timothy Lehmberg, Marisa Peluso, Ammar Adam, Li Zhang, Caroline Armet, Matthew Rausch, Benjamin Lee, Pamela Holland, Vito Palombella, Alison Paterson, Li Ren Kong, Elisa Ten Hacken, Jennifer Guerriero, Charles Herbaux, Catherine Wu, Shazib Pervaiz, Carsten Niemann, Ruben Carrasco, Matthew S Davids
Journal: Blood
Blood (2025) 146 (Supplement 1): 1525.
https://doi.org/10.1182/blood-2025-1525
Published: 2025
Journal Articles

Inhibition of PRMT5 with JNJ-64619178 sensitizes B-cell non-Hodgkin lymphoma cells to both intrinsic and extrinsic apoptosis

Free
Fen Zhu, Jing Wang, Christine Ryan, Liam Hackett, Jeremy Zhang, Stephen Chong, Matthew S Davids
Journal: Blood
Blood (2025) 146 (Supplement 1): 5076.
https://doi.org/10.1182/blood-2025-5076
Published: 2025
Journal Articles

A tandem CD19/ROR1 CAR-NK to overcome Wnt5a-mediated apoptotic resistance in chronic lymphocytic leukemia

Free
Salem Elias, Andrew Lu, Fuguo Liu, Xingyu Deng, Olivia Stringham, Jeremy Zhang, Nathalie Javidi-Sharifi, Lara Bencsics, Stephanie Chamberlain, Rizwan Romee, Matthew S Davids
Journal: Blood
Blood (2025) 146 (Supplement 1): 246.
https://doi.org/10.1182/blood-2025-246
Published: 2025
Journal Articles

Large-scale dependency and drug screens to characterize the therapeutic vulnerabilities of multiple myeloma with 1q+

Available to Purchase
Romanos Sklavenitis-Pistofidis, Elizabeth D. Lightbody, Mairead Reidy, Junko Tsuji, Jean-Baptiste Alberge, Michelle P. Aranha, Daniel Heilpern-Mallory, Harvey G. Roweth, Daisy Huynh, Stephen J. F. Chong, Anna Y. Chung, Jeremy Zhang, Liam Hackett, Nicholas J. Haradhvala, Ting Wu, Nang K. Su, Brianna Berrios, Saveliy Belkin, Ankit K. Dutta, Ryan A. Knudson, Carolyn Brandt, Patricia T. Greipp, Matthew S. Davids, Maria Papaioannou, Gad Getz, Irene M. Ghobrial, Salomon Manier
Journal: Blood
Blood (2025) 146 (1): 89–103.
https://doi.org/10.1182/blood.2024025102
Published: 2025
Includes: Supplemental data
Journal Articles

Pharmacodynamic Analysis of Mcl-1 and RNA Pol II Ser2 Phosphorylation in Blasts from Patients with Relapsed or Refractory Acute Myeloid Leukemia Treated on a Phase 1 Study of Venetoclax Plus Voruciclib

Free
Nathalie Javidi-Sharifi, Jeremy Zhang, Sandra Wiley, Richard G Ghalie, Alexey V. Danilov, Matthew S. Davids
Journal: Blood
Blood (2024) 144 (Supplement 1): 4147.
https://doi.org/10.1182/blood-2024-203689
Published: 2024
Journal Articles

Comparative Assessment of Cell Line Models for Optimal Representation of Chronic Lymphocytic Leukemia

Free
Salem Elias, Jeremy Zhang, Ritu Somayaji, Stephanie Chamberlain, Stephen Jun Fei Chong, Matthew S. Davids
Journal: Blood
Blood (2024) 144 (Supplement 1): 6759.
https://doi.org/10.1182/blood-2024-203777
Published: 2024
Journal Articles

Mechanistic Insights and Therapeutic Potential of a PRMT5 Inhibitor Combined with Venetoclax in B Cell Malignancies

Free
Fen Zhu, Jing Wang, Christine E. Ryan, Liam Hackett, Jeremy Zhang, Stephen Jun Fei Chong, Matthew S. Davids
Journal: Blood
Blood (2024) 144 (Supplement 1): 1615.
https://doi.org/10.1182/blood-2024-205802
Published: 2024
Journal Articles

Primary Endpoint Evaluation of a Multicenter, Phase 2 Study of Acalabrutinib, Venetoclax, Obinutuzumab (AVO) in a Population of Previously Untreated Patients with CLL Enriched for High-Risk Disease

Free
Matthew S. Davids, Christine E. Ryan, Yue Ren, Liam Hackett, Jeremy Zhang, Svitlana Tyekucheva, Stacey M. Fernandes, Jennifer L. Crombie, Austin I. Kim, Matthew Weinstock, Josie Montegaard, Heather A. Walker, Claire Greenman, Victoria Patterson, Caron A. Jacobson, Ann S. LaCasce, Philippe Armand, David C. Fisher, Steve Lo, Adam J. Olszewski, Jon E. Arnason, Inhye E. Ahn, Jennifer R. Brown
Journal: Blood
Blood (2024) 144 (Supplement 1): 1865.
https://doi.org/10.1182/blood-2024-206556
Published: 2024
Journal Articles

Lysosomal Membrane Permeabilization Sensitizes Ctss-Hyperactive Tumors to BCL2-Targeting Therapies

Free
Johannes Adrian Hildebrand, Sarah Haebe, Verena Passerini, Michael Heide, William Keay, Louisa Adolph, Lukas Ulrich, Natyra Tahiri, Raphael Koch, Jessica Duffy, Haley Martin, Liam Hackett, Jeremy Zhang, Christina Ludwig, Stefanie Wilhelm, Björn Häupl, Carmen Doebele, Michael von Bergwelt-Baildon, Axel Lechner, Tobias Herold, Christian Kellner, Martina Rudelius, Thomas Oellerich, Marc Schmidt-Supprian, Abner Louissaint, Matthew S Davids, Oliver Weigert
Journal: Blood
Blood (2023) 142 (Supplement 1): 4358.
https://doi.org/10.1182/blood-2023-174384
Published: 2023