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Carmen Doebele
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Journal Articles

Exceptional Response to BTK Inhibitors in Aggressive Lymphomas Linked to Chronic Selective Autophagy

James D Phelan, Sebastian Scheich, Jaewoo Choi, George Wright, Björn Häupl, Ryan M. Young, Sara Rieke, Martine Pape, Yanlong Ji, Henning Urlaub, Carmen Doebele, Alena Zindel, Tanja Wotapek, Monica Kasbekar, Da Wei Huang, Zana Coulibaly, Vivian M Morris, Xin Yu, Weihong Xu, Yandan Yang, Hong Zhao, Christopher J. Shoemaker, Zhuo Wang, Arthur Shaffer, Louis M. Staudt, Thomas Oellerich
Journal: Blood
Blood (2023) 142 (Supplement 1): 850.
https://doi.org/10.1182/blood-2023-190851
Published: 2023
Journal Articles

Lysosomal Membrane Permeabilization Sensitizes Ctss-Hyperactive Tumors to BCL2-Targeting Therapies

Johannes Adrian Hildebrand, Sarah Haebe, Verena Passerini, Michael Heide, William Keay, Louisa Adolph, Lukas Ulrich, Natyra Tahiri, Raphael Koch, Jessica Duffy, Haley Martin, Liam Hackett, Jeremy Zhang, Christina Ludwig, Stefanie Wilhelm, Björn Häupl, Carmen Doebele, Michael von Bergwelt-Baildon, Axel Lechner, Tobias Herold, Christian Kellner, Martina Rudelius, Thomas Oellerich, Marc Schmidt-Supprian, Abner Louissaint, Matthew S Davids, Oliver Weigert
Journal: Blood
Blood (2023) 142 (Supplement 1): 4358.
https://doi.org/10.1182/blood-2023-174384
Published: 2023
Journal Articles

SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma

Anne C. Wilke, Carmen Doebele, Alena Zindel, Kwang Seok Lee, Sara A. Rieke, Michele Ceribelli, Federico Comoglio, James D. Phelan, James Q. Wang, Yana Pikman, Dominique Jahn, Björn Häupl, Constanze Schneider, Sebastian Scheich, Frances A. Tosto, Hanibal Bohnenberger, Philipp Stauder, Frank Schnütgen, Mikolaj Slabicki, Zana A. Coulibaly, Sebastian Wolf, Kamil Bojarczuk, Björn Chapuy, Christian H. Brandts, Philipp Stroebel, Caroline A. Lewis, Michael Engelke, Xincheng Xu, Hahn Kim, Thanh Hung Dang, Roland Schmitz, Daniel J. Hodson, Kimberly Stegmaier, Henning Urlaub, Hubert Serve, Clemens A. Schmitt, Fernando Kreuz, Gero Knittel, Joshua D. Rabinowitz, Hans Christian Reinhardt, Matthew G. Vander Heiden, Craig Thomas, Louis M. Staudt, Thorsten Zenz, Thomas Oellerich
Journal: Blood
Blood (2022) 139 (4): 538–553.
https://doi.org/10.1182/blood.2021012081
Published: 2022
Includes: Supplemental data
Journal Articles

HSP90 promotes Burkitt lymphoma cell survival by maintaining tonic B-cell receptor signaling

Roland Walter, Kuan-Ting Pan, Carmen Doebele, Federico Comoglio, Katarzyna Tomska, Hanibal Bohnenberger, Ryan M. Young, Laura Jacobs, Ulrich Keller, Halvard Bönig, Michael Engelke, Andreas Rosenwald, Henning Urlaub, Louis M. Staudt, Hubert Serve, Thorsten Zenz, Thomas Oellerich
Journal: Blood
Blood (2017) 129 (5): 598–608.
https://doi.org/10.1182/blood-2016-06-721423
Published: 2017
Includes: Supplemental data
Journal Articles

Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling By Suppression of Mir-146a in Acute Myeloid Leukemia

Sebastian Mohr, Carmen Doebele, PhD, Tobias Berg, MD, Federico Comoglio, PhD, Julia Beck, PhD, Gabriela Alexe, PhD, Jasmin Corso, Hanibal Bohnenberger, MD, Philipp Stroebel, MD, Astrid Wachter, Tim Beissbarth, PhD, Frank Schnuetgen, PhD, Nadine Haetscher, PhD, Stefanie Goellner, PhD, Arefeh Rouhi, PhD, Lars Palmqvist, MD PhD, Michael A Rieger, PhD, Carsten Mueller-Tidow, MD, Florian Kuchenbauer, Ekkehardt Schuetz, MD, Henning Urlaub, PhD, Kimberly Stegmaier, MD, R. Keith Humphries, MD PhD, Hubert Serve, MD, Thomas Oellerich, MD
Journal: Blood
Blood (2016) 128 (22): 1533.
https://doi.org/10.1182/blood.V128.22.1533.1533
Published: 2016
Journal Articles

Phosphoproteomic Profiling of the Signaling Output of FLT3-ITD and Its AC220-Resistant Mutants Reveals Profound Signaling Differences and Differential Responsiveness to Inhibition of Downstream Kinases

Carmen Doebele, Johannes Kovar, Diego Yepes, Silvia Münch, Frank Schnütgen, Hanibal Bohnenberger, Anne Köhler, Henning Urlaub, Hubert Serve, Thomas Oellerich, MD
Journal: Blood
Blood (2015) 126 (23): 2453.
https://doi.org/10.1182/blood.V126.23.2453.2453
Published: 2015
Journal Articles

Syk and Btk Transduce Survival and Proliferation-Inducing Signals By Activating Distinct Signaling Pathways and Transcriptional Programs in AML Cells

Thomas Oellerich, Sebastian Mohr, Julia Beck, Hanibal Bohnenberger, Carmen Doebele, Jasmin Corso, Gesine Bug, Ekkehard Schuetz, Henning Urlaub, Hubert Serve, MD
Journal: Blood
Blood (2014) 124 (21): 3594.
https://doi.org/10.1182/blood.V124.21.3594.3594
Published: 2014
Journal Articles

MicroRNA-27a/b controls endothelial cell repulsion and angiogenesis by targeting semaphorin 6A

Carmen Urbich, David Kaluza, Timo Frömel, Andrea Knau, Katrin Bennewitz, Reinier A. Boon, Angelika Bonauer, Carmen Doebele, Jes-Niels Boeckel, Eduard Hergenreider, Andreas M. Zeiher, Jens Kroll, Ingrid Fleming, Stefanie Dimmeler
Journal: Blood
Blood (2012) 119 (6): 1607–1616.
https://doi.org/10.1182/blood-2011-08-373886
Published: 2012
Includes: Multimedia, Supplemental data
Journal Articles

Members of the microRNA-17-92 cluster exhibit a cell-intrinsic antiangiogenic function in endothelial cells

Carmen Doebele, Angelika Bonauer, Ariane Fischer, Alexander Scholz, Yvonne Reiss, Carmen Urbich, Wolf-Karsten Hofmann, Andreas M. Zeiher, Stefanie Dimmeler
Journal: Blood
Blood (2010) 115 (23): 4944–4950.
https://doi.org/10.1182/blood-2010-01-264812
Published: 2010
Includes: Supplemental data