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Henning Urlaub
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Journal Articles

Exceptional Response to BTK Inhibitors in Aggressive Lymphomas Linked to Chronic Selective Autophagy

James D Phelan, Sebastian Scheich, Jaewoo Choi, George Wright, Björn Häupl, Ryan M. Young, Sara Rieke, Martine Pape, Yanlong Ji, Henning Urlaub, Carmen Doebele, Alena Zindel, Tanja Wotapek, Monica Kasbekar, Da Wei Huang, Zana Coulibaly, Vivian M Morris, Xin Yu, Weihong Xu, Yandan Yang, Hong Zhao, Christopher J. Shoemaker, Zhuo Wang, Arthur Shaffer, Louis M. Staudt, Thomas Oellerich
Journal: Blood
Blood (2023) 142 (Supplement 1): 850.
https://doi.org/10.1182/blood-2023-190851
Published: 2023
Journal Articles

Molecular Determinants of Sensitivity to Polatuzumab-Vedotin in Diffuse Large B-Cell Lymphoma

Sean R Corcoran, Jaewoo Choi, Rachel E Fenner, Xin Yu, Sebastian Scheich, Tony Hsiao, Galina Schevchenko, Vivian M Morris, James D Phelan, Evangelia K Papachristou, Kamal Kishore, Clive S D'Santos, Yanlong Ji, Stefania Pittaluga, George Wright, Henning Urlaub, Kuan-Ting Pan, Thomas Oellerich, Jagan R. Muppidi, Daniel James Hodson, Louis M. Staudt
Journal: Blood
Blood (2023) 142 (Supplement 1): 2819.
https://doi.org/10.1182/blood-2023-178059
Published: 2023
Journal Articles

Proteomic Characterization of Acute Myeloid Leukemia

Sebastian Wolf, Ashok Kumar Jayavelu, Florian Buettner, Gabriela Alexe, Björn Häupl, Constanze Schneider, Anne C Wilke, Alena Zindel, Dominique Jahn, Bianca Splettstoesser, Julius Christoph Enssle, Anjali Cremer, Christoph Röllig, Christian Thiede, Björn Steffen, Martin Bornhäuser, Henning Urlaub, Kimberly Stegmaier, Hubert Serve, Matthias Mann, Thomas Oellerich
Journal: Blood
Blood (2022) 140 (Supplement 1): 3456–3457.
https://doi.org/10.1182/blood-2022-169242
Published: 2022
Journal Articles

SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma

Anne C. Wilke, Carmen Doebele, Alena Zindel, Kwang Seok Lee, Sara A. Rieke, Michele Ceribelli, Federico Comoglio, James D. Phelan, James Q. Wang, Yana Pikman, Dominique Jahn, Björn Häupl, Constanze Schneider, Sebastian Scheich, Frances A. Tosto, Hanibal Bohnenberger, Philipp Stauder, Frank Schnütgen, Mikolaj Slabicki, Zana A. Coulibaly, Sebastian Wolf, Kamil Bojarczuk, Björn Chapuy, Christian H. Brandts, Philipp Stroebel, Caroline A. Lewis, Michael Engelke, Xincheng Xu, Hahn Kim, Thanh Hung Dang, Roland Schmitz, Daniel J. Hodson, Kimberly Stegmaier, Henning Urlaub, Hubert Serve, Clemens A. Schmitt, Fernando Kreuz, Gero Knittel, Joshua D. Rabinowitz, Hans Christian Reinhardt, Matthew G. Vander Heiden, Craig Thomas, Louis M. Staudt, Thorsten Zenz, Thomas Oellerich
Journal: Blood
Blood (2022) 139 (4): 538–553.
https://doi.org/10.1182/blood.2021012081
Published: 2022
Includes: Supplemental data
Journal Articles

HSP90 promotes Burkitt lymphoma cell survival by maintaining tonic B-cell receptor signaling

Roland Walter, Kuan-Ting Pan, Carmen Doebele, Federico Comoglio, Katarzyna Tomska, Hanibal Bohnenberger, Ryan M. Young, Laura Jacobs, Ulrich Keller, Halvard Bönig, Michael Engelke, Andreas Rosenwald, Henning Urlaub, Louis M. Staudt, Hubert Serve, Thorsten Zenz, Thomas Oellerich
Journal: Blood
Blood (2017) 129 (5): 598–608.
https://doi.org/10.1182/blood-2016-06-721423
Published: 2017
Includes: Supplemental data
Journal Articles

Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling By Suppression of Mir-146a in Acute Myeloid Leukemia

Sebastian Mohr, Carmen Doebele, PhD, Tobias Berg, MD, Federico Comoglio, PhD, Julia Beck, PhD, Gabriela Alexe, PhD, Jasmin Corso, Hanibal Bohnenberger, MD, Philipp Stroebel, MD, Astrid Wachter, Tim Beissbarth, PhD, Frank Schnuetgen, PhD, Nadine Haetscher, PhD, Stefanie Goellner, PhD, Arefeh Rouhi, PhD, Lars Palmqvist, MD PhD, Michael A Rieger, PhD, Carsten Mueller-Tidow, MD, Florian Kuchenbauer, Ekkehardt Schuetz, MD, Henning Urlaub, PhD, Kimberly Stegmaier, MD, R. Keith Humphries, MD PhD, Hubert Serve, MD, Thomas Oellerich, MD
Journal: Blood
Blood (2016) 128 (22): 1533.
https://doi.org/10.1182/blood.V128.22.1533.1533
Published: 2016
Journal Articles

Phosphoproteomic Profiling of the Signaling Output of FLT3-ITD and Its AC220-Resistant Mutants Reveals Profound Signaling Differences and Differential Responsiveness to Inhibition of Downstream Kinases

Carmen Doebele, Johannes Kovar, Diego Yepes, Silvia Münch, Frank Schnütgen, Hanibal Bohnenberger, Anne Köhler, Henning Urlaub, Hubert Serve, Thomas Oellerich, MD
Journal: Blood
Blood (2015) 126 (23): 2453.
https://doi.org/10.1182/blood.V126.23.2453.2453
Published: 2015
Journal Articles

Identification of B Cell Receptor Antigens in the Chronic Lymphocytic Leukemia Microenvironment

Elisa ten Hacken, PhD, Thomas Oellerich, MD, Maria Gounari, PhD, Julia Hoellenriegel, MS, Kuan-Ting Pan, PhD, Susan O'Brien, MD, William Wierda, MD PhD, Alessandra Ferrajoli, MD, Zeev Estrov, MD, Michael J. Keating, MD, Henning Urlaub, PhD, Paolo Ghia, MD PhD, Jan A. Burger, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2922.
https://doi.org/10.1182/blood.V126.23.2922.2922
Published: 2015
Journal Articles

RUNX1 represses the erythroid gene expression program during megakaryocytic differentiation

Olga N. Kuvardina, Julia Herglotz, Stephan Kolodziej, Nicole Kohrs, Stefanie Herkt, Bartosch Wojcik, Thomas Oellerich, Jasmin Corso, Kira Behrens, Ashok Kumar, Helge Hussong, Henning Urlaub, Joachim Koch, Hubert Serve, Halvard Bonig, Carol Stocking, Michael A. Rieger, Jörn Lausen
Journal: Blood
Blood (2015) 125 (23): 3570–3579.
https://doi.org/10.1182/blood-2014-11-610519
Published: 2015
Includes: Supplemental data
Journal Articles

FLT3-ITD and TLR9 use Bruton tyrosine kinase to activate distinct transcriptional programs mediating AML cell survival and proliferation

Thomas Oellerich, Sebastian Mohr, Jasmin Corso, Julia Beck, Carmen Döbele, Helene Braun, Anjali Cremer, Silvia Münch, Johannes Wicht, Mark F. Oellerich, Gesine Bug, Hanibal Bohnenberger, Christina Perske, Ekkehard Schütz, Henning Urlaub, Hubert Serve
Journal: Blood
Blood (2015) 125 (12): 1936–1947.
https://doi.org/10.1182/blood-2014-06-585216
Published: 2015
Includes: Supplemental data
Journal Articles

Syk and Btk Transduce Survival and Proliferation-Inducing Signals By Activating Distinct Signaling Pathways and Transcriptional Programs in AML Cells

Thomas Oellerich, Sebastian Mohr, Julia Beck, Hanibal Bohnenberger, Carmen Doebele, Jasmin Corso, Gesine Bug, Ekkehard Schuetz, Henning Urlaub, Hubert Serve, MD
Journal: Blood
Blood (2014) 124 (21): 3594.
https://doi.org/10.1182/blood.V124.21.3594.3594
Published: 2014
Journal Articles

Deciphering The Molecular Impact Of Myc Overexpression On B Cell Receptor Signaling and Its Implications For Burkitt Lymphoma Treatment

Thomas Oellerich, Jasmin Corso, Simone Lemeer, Ekkehard Schütz, Julia Beck, Stephan Lorenzen, Tim Beissbarth, Silvia Münch, Pascal Degenhardt, Michael Engelke, Christoph Lenz, Bernhard Küster, Henning Urlaub, Hubert Serve, MD
Journal: Blood
Blood (2013) 122 (21): 3018.
https://doi.org/10.1182/blood.V122.21.3018.3018
Published: 2013
Journal Articles

β 2 integrin–derived signals induce cell survival and proliferation of AML blasts by activating a Syk/STAT signaling axis

Thomas Oellerich, Mark F. Oellerich, Michael Engelke, Silvia Münch, Sebastian Mohr, Marika Nimz, He-Hsuan Hsiao, Jasmin Corso, Jing Zhang, Hanibal Bohnenberger, Tobias Berg, Michael A. Rieger, Jürgen Wienands, Gesine Bug, Christian Brandts, Henning Urlaub, Hubert Serve
Journal: Blood
Blood (2013) 121 (19): 3889–3899.
https://doi.org/10.1182/blood-2012-09-457887
Published: 2013
Includes: Supplemental data
Journal Articles

Elucidation of B Cell Antigen Receptor Signaling by Global Phosphoproteomics Reveals Novel Signaling Pathways and Regulatory Mechanisms

Thomas Oellerich, Dr. med., Jasmin Corso, Michael Engelke, Dr., Daniel Stanze, MD, He-Hsuan Hsiao, Dr., Juergen Wienands, Prof. Dr., Henning Urlaub, Prof. Dr., Hubert Serve, Prof. Dr. med.
Journal: Blood
Blood (2012) 120 (21): 1056.
https://doi.org/10.1182/blood.V120.21.1056.1056
Published: 2012