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Journal Articles

Exceptional Response to BTK Inhibitors in Aggressive Lymphomas Linked to Chronic Selective Autophagy

James D Phelan, Sebastian Scheich, Jaewoo Choi, George Wright, Björn Häupl, Ryan M. Young, Sara Rieke, Martine Pape, Yanlong Ji, Henning Urlaub, Carmen Doebele, Alena Zindel, Tanja Wotapek, Monica Kasbekar, Da Wei Huang, Zana Coulibaly, Vivian M Morris, Xin Yu, Weihong Xu, Yandan Yang, Hong Zhao, Christopher J. Shoemaker, Zhuo Wang, Arthur Shaffer, Louis M. Staudt, Thomas Oellerich
Journal: Blood
Blood (2023) 142 (Supplement 1): 850.
https://doi.org/10.1182/blood-2023-190851
Published: 2023
Journal Articles

Molecular Determinants of Sensitivity to Polatuzumab-Vedotin in Diffuse Large B-Cell Lymphoma

Sean R Corcoran, Jaewoo Choi, Rachel E Fenner, Xin Yu, Sebastian Scheich, Tony Hsiao, Galina Schevchenko, Vivian M Morris, James D Phelan, Evangelia K Papachristou, Kamal Kishore, Clive S D'Santos, Yanlong Ji, Stefania Pittaluga, George Wright, Henning Urlaub, Kuan-Ting Pan, Thomas Oellerich, Jagan R. Muppidi, Daniel James Hodson, Louis M. Staudt
Journal: Blood
Blood (2023) 142 (Supplement 1): 2819.
https://doi.org/10.1182/blood-2023-178059
Published: 2023
Journal Articles

Molecular Mechanism of Action of Glucocorticoids in Lymphoma Therapy

Jaewoo Choi, Michele Ceribelli, James D Phelan, Björn Häupl, Da Wei Huang, George Wright, Tony Hsiao, Vivian M Morris, Francesco Ciccarese, Boya Wang, Sean R Corcoran, Sebastian Scheich, Xin Yu, Weihong Xu, Yandan Yang, Joyce Zhou, Grace Zhang, Jagan R. Muppidi, Giorgio Inghirami, Thomas Oellerich, Craig J. Thomas, Louis M. Staudt
Journal: Blood
Blood (2023) 142 (Supplement 1): 2986.
https://doi.org/10.1182/blood-2023-174325
Published: 2023
Journal Articles

Clinical Implications of CSF-Ctdna in CNS Involvement of Newly Diagnosed Diffuse Large B Cell Lymphoma: An Improvement of Diagnosis, Treatment and Evaluation

Jinhua Liang, Yi-fan Wu, Hao-Rui Shen, Yue Li, Jun-heng Liang, Xin-Yu Zhang, Sibusiso Luthuli, Jiazhu Wu, Liu qing Zhu, Hua Yin, Li Wang, Jianyong Li, Xu Wei
Journal: Blood
Blood (2023) 142 (Supplement 1): 188.
https://doi.org/10.1182/blood-2023-181666
Published: 2023
Journal Articles

Efficacy and Safety of Avatrombopag in the Treatment of Chemotherapy-Induced Thrombocytopenia Refractory to Rhtpo in Patients with Lymphoma

Xu Wei, Hao-Rui Shen, Xin-Yu Zhang, Jiazhu Wu, Hua Yin, Yue Li, Jinhua Liang, Li Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 5452.
https://doi.org/10.1182/blood-2023-184420
Published: 2023
Journal Articles

Enasidenib vs conventional care in older patients with late-stage mutant- IDH2 relapsed/refractory AML: a randomized phase 3 trial

Clinical Trials & Observations
Stéphane de Botton, Pau Montesinos, Andre C. Schuh, Cristina Papayannidis, Paresh Vyas, Andrew H. Wei, Hans Ommen, Sergey Semochkin, Hee-Je Kim, Richard A. Larson, Jaime Koprivnikar, Olga Frankfurt, Felicitas Thol, Jörg Chromik, Jenny Byrne, Arnaud Pigneux, Xavier Thomas, Olga Salamero, Maria Belen Vidriales, Vadim Doronin, Hartmut Döhner, Amir T. Fathi, Eric Laille, Xin Yu, Maroof Hasan, Patricia Martin-Regueira, Courtney D. DiNardo
Journal: Blood
Blood (2023) 141 (2): 156–167.
https://doi.org/10.1182/blood.2021014901
Published: 2023
Includes: Supplemental data
Journal Articles

Alternative Splicing of Bcap (PIK3AP1) Enhances Oncogenic Signaling in Subsets of Activated B-Cell Diffuse Large B-Cell Lymphoma

Andy Itsara, Sebastian Scheich, Björn Häupl, Xin Yu, Thomas Oellerich, Louis M. Staudt
Journal: Blood
Blood (2022) 140 (Supplement 1): 6394–6395.
https://doi.org/10.1182/blood-2022-163619
Published: 2022
Journal Articles

Machine Learning Algorithm As a Prognostic Tool for Epstein-Barr Virus Reactivation after Haploidentical Hematopoietic Stem Cell Transplantation

Shuang Fan, Hao-Yang Hong, Xin-Yu Dong, Lan-Ping Xu, Xiao-hui Zhang, Yu Wang, Chen-Hua Yan, Huan Chen, Yu-Hong Chen, Wei Han, Fengrong Wang, Jing-Zhi Wang, Kaiyan Liu, Meng-Zhu Shen, Xiao-jun Huang, Shen-Da Hong, Xiao-Dong Mo
Journal: Blood
Blood (2022) 140 (Supplement 1): 7691–7692.
https://doi.org/10.1182/blood-2022-165067
Published: 2022
Journal Articles

Outcomes for Patients with Late-Stage Mutant- IDH2 (m IDH2 ) Relapsed/Refractory Acute Myeloid Leukemia (R/R AML) Treated with Enasidenib Vs Other Lower-Intensity Therapies in the Randomized, Phase 3 IDHentify Trial

Courtney D. DiNardo, Pau Montesinos, Andre C. Schuh, Cristina Papayannidis, Paresh Vyas, Andrew H. Wei, Amer M. Zeidan, Iryna Bluemmert, Xin Yu, Maroof Hasan, Patricia Martin-Regueira, Stephane de Botton
Journal: Blood
Blood (2021) 138 (Supplement 1): 1243.
https://doi.org/10.1182/blood-2021-147593
Published: 2021
Journal Articles

Health-Related Quality of Life Among Patients with Relapsed or Refractory Multiple Myeloma Who Received Pomalidomide, Bortezomib, and Low-Dose Dexamethasone Versus Bortezomib and Low-Dose Dexamethasone - Results from the Phase 3 Optimismm Study

Katja Weisel, MD, Meletios A Dimopoulos, MD, Philippe Moreau, Munci Yagci, Alessandra Larocca, MD, Abraham S. Kanate, MD, Filiz Vural, Nicola Cascavilla, MD, Supratik Basu, MBBS, MD FRCP, FRCPath, Peter Johnson, Peter D. Byeff, MD, Marek Hus, Paula Rodriguez Otero, MD, Kosei Matsue, MD PhD, Ercan Muelduer, Pekka Anttila, MD, Patrick Hayden, Maria-Theresa Krauth, MD, Dina Ben-Yehuda, MD, Larisa P. Mendeleeva, MD PhD Prof, Shien Guo, Lea Purnomo, Xin Yu, Lara Grote, Tsvetan Biyukov, MD, Mohamed Zaki, MD PhD, Paul Richardson
Journal: Blood
Blood (2018) 132 (Supplement 1): 1960.
https://doi.org/10.1182/blood-2018-99-112155
Published: 2018
Journal Articles

Pomalidomide + Bortezomib + Low-Dose Dexamethasone Vs Bortezomib + Low-Dose Dexamethasone As Second-Line Treatment in Patients with Lenalidomide-Pretreated Multiple Myeloma: A Subgroup Analysis of the Phase 3 Optimismm Trial

Meletios A Dimopoulos, MD, Katja Weisel, MD, Philippe Moreau, Larry Anderson, MD PhD, Darrell J White, MD, Jesus F San-Miguel, MD PhD, Pieter Sonneveld, MD PhD, Monika Engelhardt, MD, Matthew W Jenner, Alessandro Corso, MD, Jan Dürig, Michel Pavic, MD, Morten Salomo, Xin Yu, Tuong Vi Nguyen, Amine Bensmaine, Teresa Peluso, Mohamed Zaki, MD PhD, Paul Richardson
Journal: Blood
Blood (2018) 132 (Supplement 1): 3278.
https://doi.org/10.1182/blood-2018-99-111869
Published: 2018
Journal Articles

Targeting the HTLV-I-Regulated BATF3/IRF4 Transcriptional Network in Adult T-Cell Leukemia/Lymphoma

Masao Nakagawa, MD, Arthur L Shaffer, Michele Ceribelli, Meili Zhang, PhD, George Wright, Da Wei Huang, Wenming Xiao, John Powell, Michael N Petrus, Yibin Yang, James D Phelan, Holger Kohlhammer, Hee Min Yoo, Yandan Yang, Weihong Xu, Xin Yu, Hong Zhao, Bonita R Bryant, Michiyuki Maeda, Thomas A Waldmann, MD, Lou Staudt, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 731.
https://doi.org/10.1182/blood.V130.Suppl_1.731.731
Published: 2017
Journal Articles

Correlative Analyses of Cereblon ( CRBN ), cMYC , IRF4 , BLIMP1 , and XBP1 with Clinical Outcomes in Stratus (MM-010), a Phase 3b Study of Pomalidomide (POM) + Low-Dose Dexamethasone (LoDEX) in Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM)

Xiaozhong Qian, Meletios A. Dimopoulos, Michael Amatangelo, PhD, Chad Bjorklund, Katja C. Weisel, Enrique M. Ocio, MDPhD, Xin Yu, Teresa Peluso, Lars Sternas, Mohamed Zaki, Philippe Moreau, MDPhD, Anjan Thakurta, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3109.
https://doi.org/10.1182/blood.V130.Suppl_1.3109.3109
Published: 2017
Journal Articles

Peripheral Neuropathy (PN) with Immunomodulatory Drugs in Patients with Multiple Myeloma (MM)

Melinda Mezo, Carmen Castaneda, Lilia Weiss, Neil Minton, Damien Hirsch, Christine Renz, Uma Arunagiri, MD, Benton Brown, Dominique Gambini, MD, Michael Peng, Zhinuan Yu, PhD, Xin Yu, John Freeman
Journal: Blood
Blood (2016) 128 (22): 5677.
https://doi.org/10.1182/blood.V128.22.5677.5677
Published: 2016
Journal Articles

Genome-Scale ORF Screen for Mediators of NF-κb Activation in DLBCL

Hee Min Yoo, PhD, Roland Schmitz, Xin Yu, Da Wei Huang, James D. Phelan, Daniel E. Webster, Louis M. Staudt, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4102.
https://doi.org/10.1182/blood.V128.22.4102.4102
Published: 2016
Journal Articles

Analysis of Pomalidomide Plus Low-Dose Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma with Vs without Moderate Renal Impairment

David S Siegel, Katja C. Weisel, Meletios A. Dimopoulos, Rachid Baz, Paul G. Richardson, Michel Delforge, Kevin Song, Jesus San Miguel, MD PhD, Philippe Moreau, Xin Yu, Kevin Hong, Lars Sternas, Mohamed H Zaki, Antonio Palumbo
Journal: Blood
Blood (2015) 126 (23): 3031.
https://doi.org/10.1182/blood.V126.23.3031.3031
Published: 2015
Journal Articles

Pomalidomide Plus Low-Dose Dexamethasone (POM + LoDEX) for Relapsed and Refractory Multiple Myeloma (RRMM): Results from a Pharmacoeconomic Evaluation

Steve Schey, Sujith Dhanasiri, Dawn Lee, Lars Sternas, MD, Xin Yu, Mohamed H. Zaki, MD, Jamie Elvidge, Michael O'Dwyer
Journal: Blood
Blood (2014) 124 (21): 2649.
https://doi.org/10.1182/blood.V124.21.2649.2649
Published: 2014
Journal Articles

MM-003 Phase 3 Study Of Pomalidomide In Combination With Low-Dose Dexamethasone (POM + LoDEX) Vs High-Dose Dexamethasone (HiDEX) In Relapsed/Refractory Multiple Myeloma (RRMM): POM + Lodex Is Beneficial For Elderly Patients (> 65 Years of Age)

Katja Weisel, MD, Jesús F. San Miguel, MD, PhD, Kevin W. Song, MD, FRCPC, Michel Delforge, MD, PhD, Lionel Karlin, MD, Hartmut Goldschmidt, MD, Philippe Moreau, MD, Anne Banos, MD, Albert Oriol, MD, Laurent Garderet, MD, Michele Cavo, MD, Valentina Ivanova, MD, PhD, Adrian Alegre, MD, Joaquin Martinez-Lopez, Christine I. Chen, MD, Stefan Knop, MD, Xin Yu, PhD, Latisha Watkins, Lars Sternas, MD, Christian Jacques, MD, Mohamed H. Zaki, MD, PhD, Meletios A. Dimopoulos, MD
Journal: Blood
Blood (2013) 122 (21): 3198.
https://doi.org/10.1182/blood.V122.21.3198.3198
Published: 2013
Journal Articles

Pomalidomide (POM) Plus Low-Dose Dexamethasone (LoDEX) Improves Health-Related Quality Of Life (HRQoL) Vs High-Dose Dexamethasone (HiDEX) In Relapsed Refractory Multiple Myeloma (RRMM) Patients Enrolled In MM-003 Phase 3 Randomized Trial

Kevin W. Song, MD, FRCPC, Meletios A. Dimopoulos, MD, Katja Weisel, MD, Michel Delforge, MD, PhD, Lionel Karlin, MD, Hartmut Goldschmidt, MD, Philippe Moreau, MD, Anne Banos, MD, Albert Oriol, MD, Andrew Spencer, MD, Stefan Knop, MD, Christoph Renner, MD, Nizar J Bahlis, MD, Ramesh Amatya, PhD, Xin Yu, PhD, Mara Silvia Monzini, Lars Sternas, MD, Mohamed H. Zaki, MD, PhD, Christian J. Jacques, MD, Jesús F. San Miguel, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2939.
https://doi.org/10.1182/blood.V122.21.2939.2939
Published: 2013
Journal Articles

Final Analysis, Cytogenetics, Long-Term Treatment, and Long-Term Survival In MM-003, A Phase 3 Study Comparing Pomalidomide + Low-Dose Dexamethasone (POM + LoDEX) Vs High-Dose Dexamethasone (HiDEX) In Relapsed/Refractory Multiple Myeloma (RRMM)

Meletios A. Dimopoulos, MD, Katja Weisel, MD, Kevin W. Song, MD, FRCPC, Michel Delforge, MD, PhD, Lionel Karlin, MD, Hartmut Goldschmidt, MD, Philippe Moreau, MD, Anne Banos, MD, Albert Oriol, MD, Laurent Garderet, MD, Michele Cavo, MD, Valentina Ivanova, MD, PhD, Adrian Alegre, MD, Joaquin Martinez-Lopez, Christine I. Chen, MD, Andrew Spencer, MD, Stefan Knop, MD, Nizar J. Bahlis, MD, Christoph Renner, MD, Xin Yu, PhD, Kevin Hong, MS, Lars Sternas, MD, Christian Jacques, MD, Mohamed H. Zaki, MD, PhD, Jesús F. San Miguel, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 408.
https://doi.org/10.1182/blood.V122.21.408.408
Published: 2013