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Sandra Wiley
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Journal Articles

Orally Bioavailable CDK9 Inhibitor Voruciclib Downregulates Oncogenic Pathways in Leukemic Cells from Patients Treated on a Clinical Trial

Free
Edward C. Dominguez, Carly Roleder, Canping Chen, Zheng Xia, Sandra Wiley, Matthew S. Davids, Alexey Danilov
Journal: Blood
Blood (2024) 144 (Supplement 1): 721.
https://doi.org/10.1182/blood-2024-198693
Published: 2024
Journal Articles

Pharmacodynamic Analysis of Mcl-1 and RNA Pol II Ser2 Phosphorylation in Blasts from Patients with Relapsed or Refractory Acute Myeloid Leukemia Treated on a Phase 1 Study of Venetoclax Plus Voruciclib

Free
Nathalie Javidi-Sharifi, Jeremy Zhang, Sandra Wiley, Richard G Ghalie, Alexey V. Danilov, Matthew S. Davids
Journal: Blood
Blood (2024) 144 (Supplement 1): 4147.
https://doi.org/10.1182/blood-2024-203689
Published: 2024
Journal Articles

A Phase 1 Study of the Oral CDK9 Inhibitor Voruciclib in Combination with Venetoclax in Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)

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Yesid Alvarado-Valero, Rachel J. Cook, Shira N. Dinner, Michael Keng, Kebede Begna, Sameem Abedin, MHD Monzr M. Al Malki, Vijaya Raj Bhatt, Nathalie Javidi-Sharifi, Prabhu Rajagopolan, Sandra Wiley, Richard G Ghalie, Matthew S. Davids
Journal: Blood
Blood (2024) 144 (Supplement 1): 2878.
https://doi.org/10.1182/blood-2024-198718
Published: 2024
Journal Articles

A Novel Isoflavone, ME-344, Enhances Venetoclax Antileukemic Activity Against AML Via Suppression of Oxidative Phosphorylation and Purine Biosynthesis

Free
Katie Hege Hurrish, Yongwei Su, Sandra Wiley, Zhanjun Hou, Jenna Carter, Hasini Kalpage, Maik Hüttemann, Holly Edwards, Lisa Polin, Jing Li, Jay Yang, Larry Matherly, Jeffrey W. Taub, Yubin Ge
Journal: Blood
Blood (2021) 138 (Supplement 1): 2238.
https://doi.org/10.1182/blood-2021-147004
Published: 2021