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Journal Articles

131 I-Apamistamab-Led Allogeneic Hematopoietic Cell Transplant Significantly Improves Overall Survival in Patients with TP53 Mutated R/R AML

Hannah Choe, Ben K. Tomlinson, Boglarka Gyurkocza, Rajneesh Nath, Stuart Seropian, Mark R. Litzow, Camille N. Abboud, Patrick J. Stiff, Sunil Abhyankar, James M. Foran, Sameem Abedin, George Chen, Zaid Al-Kadhimi, Partow Kebriaei, Mitchell Sabloff, Johnnie J. Orozco, Katarzyna Joanna Jamieson, Margarida Magalhaes-Silverman, Koen Van Besien, Michael W. Schuster, Arjun D. Law, Sebastian A. Mayer, Hillard M. Lazarus, Jennifer Spross, Kate L Li, Elaina Haeuber, Madhuri Vusirikala, Akash Nahar, Brenda M. Sandmaier, John Pagel, Sergio A. Giralt, Avinash Desai, Nebu Koshy
Journal: Blood
Blood (2023) 142 (Supplement 1): 469.
https://doi.org/10.1182/blood-2023-182177
Published: 2023
Journal Articles

131 I-Apamistamab Effectively Achieved Durable Responses in Patients with R/R AML Irrespective of the Presence of Multiple High-Risk Factors

Stuart Seropian, James M. Foran, Boglarka Gyurkocza, Rajneesh Nath, Hannah Choe, Mark R. Litzow, Nebu Koshy, Patrick J. Stiff, Ben K. Tomlinson, Sunil Abhyankar, Sameem Abedin, George Chen, Zaid Al-Kadhimi, Partow Kebriaei, Mitchell Sabloff, Johnnie J. Orozco, Katarzyna Joanna Jamieson, Margarida Magalhaes-Silverman, Koen Van Besien, Michael W. Schuster, Arjun D. Law, Sebastian A. Mayer, Hillard M. Lazarus, Jennifer Spross, Kate L Li, Elaina Haeuber, Madhuri Vusirikala, Akash Nahar, Brenda M. Sandmaier, John Pagel, Sergio A. Giralt, Avinash Desai, Camille N. Abboud
Journal: Blood
Blood (2023) 142 (Supplement 1): 2159.
https://doi.org/10.1182/blood-2023-187433
Published: 2023
Journal Articles

A Phase 1 Study of the Oral CDK9 Inhibitor Voruciclib in Relapsed/Refractory (R/R) B-Cell Lymphoma (NHL) or Acute Myeloid Leukemia (AML)

Matthew S Davids, Yesid Alvarado Valero, Catherine Diefenbach, Daniel N. Egan, Shira N. Dinner, Monzr M. Al Malki, Kebede Begna, Avyakta Kallam, Sameem Abedin, Rachel Cook, Nathalie Javidi-Sharifi, Edward Dominguez, Lu Miao, Richard G Ghalie, Alexey Danilov
Journal: Blood
Blood (2023) 142 (Supplement 1): 4286.
https://doi.org/10.1182/blood-2023-179577
Published: 2023
Journal Articles

A First-in-Human Phase 1 Study of the Menin-KMT2A (MLL1) Inhibitor JNJ-75276617 in Adult Patients with Relapsed/Refractory Acute Leukemia Harboring KMT2A or NPM1 Alterations

Elias Jabbour, Emma Searle, Maher Abdul-Hay, Sameem Abedin, Ibrahim Aldoss, Ana Alfonso Piérola, Juan Manuel Alonso-Dominguez, Patrice Chevallier, Carrye Cost, Nikki Daskalakis, Richard Dillon, Neil Dunavin, Jordi Esteve, Amir T. Fathi, Pasquale L. Fedele, Lucille Ferrante, Sylvain Garciaz, Christina Guttke, Emmanuel Gyan, Brett Hiebert, Min Chul Kwon, Jonathan Miller, Teng Fong Ng, Kathryn Packman, Ulrike Philippar, Arnaud Pigneux, Christian Recher, Olga Salamero, Madhu Sanga, Richard M Stone, Peter Tan, Jan Willem Thuring, Trevor Tucker, Paresh Vyas
Journal: Blood
Blood (2023) 142 (Supplement 1): 57.
https://doi.org/10.1182/blood-2023-172422
Published: 2023
Journal Articles

Comparative Analysis of Clinical Outcomes and Healthcare Resource Utilization (HRU) in Patients (Pts) with Newly Diagnosed (ND) Acute Myeloid Leukemia (AML) Unfit for High-Intensity Chemotherapy Treated with Venetoclax (VEN) Vs Other Therapies: Results from the AML Real World Evidence (ARC) Initiative

Pinkal Desai, Jacqueline S. Garcia, Joshua F. Zeidner, Sameem Abedin, Ofir Wolach, Pankit Vachhani, Yakir Moshe, Daniel A. Pollyea, Catherine Lai, Thomas W LeBlanc, Marin Xavier, Boaz Nachmias, Evan C. Chen, Srilakshmi Bathini, Inderpreet Bhatti, Cat N. Bui, Annie Guérin, Rebecca Burne, Esprit Ma, Moshe Grunspan, Neta Frankel, Aaron D. Goldberg
Journal: Blood
Blood (2023) 142 (Supplement 1): 5173.
https://doi.org/10.1182/blood-2023-173283
Published: 2023
Journal Articles

High-Dose Targeted Radiation with 131 I-Apamistamab Prior to HCT Demonstrated a Dose-Response for Durable Complete Remission in Patients with R/R AML

Mark R. Litzow, George Chen, Boglarka Gyurkocza, Rajneesh Nath, Stuart Seropian, Hannah Choe, Camille N. Abboud, Nebu Koshy, Ben K. Tomlinson, Sunil Abhyankar, James M. Foran, Sameem Abedin, Zaid Al-Kadhimi, Partow Kebriaei, Mitchell Sabloff, Johnnie J. Orozco, Katarzyna Joanna Jamieson, Margarida Magalhaes-Silverman, Koen Van Besien, Michael W. Schuster, Arjun D. Law, Sebastian A. Mayer, Hillard M. Lazarus, Eugene Leung, Ming-Kai Chen, Mona Natwa, Jennifer Spross, Kate L Li, Norman Nagl, Elaina Haeuber, Madhuri Vusirikala, Akash Nahar, Brenda M. Sandmaier, John Pagel, Sergio A. Giralt, Avinash Desai, Richard L. Wahl, Neeta Pandit-Taskar, Patrik Brodin, Patrick J. Stiff
Journal: Blood
Blood (2023) 142 (Supplement 1): 3529.
https://doi.org/10.1182/blood-2023-189040
Published: 2023
Journal Articles

Maintenance Ruxolitinib Is Associated with Low Rates of Chronic Gvhd Requiring Systemic Treatment in Older Adults with AML/MDS Undergoing Allogeneic HCT: Results of a Phase II Multicenter Trial

Zachariah Defilipp, Haesook T. Kim, Laura Knight, Suzanne O'Connor, Meghan White, Bhagirathbhai Dholaria, Mark A. Schroeder, Sumithira Vasu, Sameem Abedin, Areej El-Jawahri, Steven McAfee, Yi-Bin Chen, Gabriela S. Hobbs
Journal: Blood
Blood (2023) 142 (Supplement 1): 653.
https://doi.org/10.1182/blood-2023-180423
Published: 2023
Journal Articles

Obecabtagene Autoleucel (obe-cel, AUTO1) for Relapsed/Refractory Adult B-cell Acute Lymphoblastic Leukemia (R/R B-ALL): Pooled Analysis of the Ongoing FELIX Phase Ib/II Study

Claire Roddie, Karamjeet S. Sandhu, Eleni Tholouli, Paul Shaughnessy, Pere Barba, Manuel Guerreiro, Michael R. Bishop, Jean A. Yared, Armin Ghobadi, Deborah Yallop, Aaron C. Logan, Amer M. Beitinjaneh, Jeremy M. Pantin, Martha Arellano, Sridhar Chaganti, Ram Malladi, Tobias Menne, Virginia Escamilla Gómez, Katharine Hodby, Krishna Gundabolu, Luke Mountjoy, Kristen M. O'Dwyer, Sameem Abedin, Hassan Alkhateeb, Bijal D. Shah, Pierre Lao-Sirieix, Gianfranco Pittari, Kapil Saxena, Yiyun Zhang, Wolfram Brugger, Martin A. Pule, Jae H. Park, Daniel J. DeAngelo, Elias Jabbour
Journal: Blood
Blood (2023) 142 (Supplement 1): 222.
https://doi.org/10.1182/blood-2023-179454
Published: 2023
Journal Articles

Infectious and Non-Infectious Pulmonary Complications in HCT Patients Treated with Post Transplant Cyclophosphamide (PTCy) Based Gvhd Prophylaxis

Skyler Taylor, Annie Kim, Paul Cho, Kinaya Smith, Mehdi Hamadani, Sameem Abedin
Journal: Blood
Blood (2023) 142 (Supplement 1): 6990.
https://doi.org/10.1182/blood-2023-184702
Published: 2023
Journal Articles

Comparison of Patients with Newly Diagnosed (ND) Acute Myeloid Leukemia (AML) Treated with Venetoclax and Hypomethylating Agents Vs Other Therapies By TP53 and IDH1/2 Mutation: Results from the AML Real World Evidence (ARC) Initiative

Ofir Wolach, Jacqueline S. Garcia, Pinkal Desai, Pankit Vachhani, Joshua F. Zeidner, Sameem Abedin, Kendra Sweet, Catherine Lai, Yakir Moshe, Daniel A. Pollyea, Marin Xavier, Boaz Nachmias, Tsila Zuckerman, Sangmin Lee, Evan C. Chen, Srilakshmi Bathini, Wesleigh Edwards, Cat N. Bui, Wei-Han Cheng, Catherine Miller, Annie Guerin, Jessica Maitland, Esprit Ma, Melissa Montez, Moshe Grunspan, Aaron D Goldberg
Journal: Blood
Blood (2022) 140 (Supplement 1): 11026–11028.
https://doi.org/10.1182/blood-2022-159615
Published: 2022
Journal Articles

Outcomes of Patients Treated with Low-Intensity Re-Induction Therapy for Persistent Disease after a Single Intensive Induction Cycle for Newly Diagnosed Acute Myeloid Leukemia (AML)

Sameem Abedin, Skyler Taylor, Guru Subramanian Guru Murthy, Lyndsey Runaas, Laura C. Michaelis, Karen-Sue Carlson, Ehab L. Atallah
Journal: Blood
Blood (2022) 140 (Supplement 1): 11020–11021.
https://doi.org/10.1182/blood-2022-160416
Published: 2022
Journal Articles

Lintuzumab-Ac225 with Combination with Intensive Chemotherapy Yields High Response Rate and MRD Negativity in R/R AML with Adverse Features

Sameem Abedin, Guru Subramanian Guru Murthy, Aniko Szabo, Mehdi Hamadani, Laura C. Michaelis, Karen-Sue Carlson, Lyndsey Runaas, Katelyn Gauger, Avinash G Desai, Mary M Chen, Alexandra M. Harrington, Ehab L. Atallah
Journal: Blood
Blood (2022) 140 (Supplement 1): 157–158.
https://doi.org/10.1182/blood-2022-157827
Published: 2022
Journal Articles

Haploidentical Donor Transplantation with Posttransplantation Cyclophosphamide in Myelodysplastic/Myeloproliferative Neoplasms: A Multi-Institutional Collaboration of 14 Centers

Tania Jain, Hua-Ling Tsai, Hany Elmariah, Pankit Vachhani, Theodoros Karantanos, Sarah A Wall, Lukasz P. Gondek, Asad Bashey, Alla Keyzner, Michael R. Grunwald, Sameem Abedin, Kalyan VG Nadiminti, Madiha Iqbal, Aaron T. Gerds, Auro Viswabandya, Shannon R McCurdy, MHD Monzr M. Al Malki, Ravi Varadhan, Haris Ali, Vikas Gupta, Richard J. Jones, Salman Otoukesh
Journal: Blood
Blood (2022) 140 (Supplement 1): 7731–7733.
https://doi.org/10.1182/blood-2022-157985
Published: 2022
Journal Articles

Standardized Communication Tool Improves Inpatient-Outpatient Care Transitions for Adults with Acute Leukemia

Jordan R. Hanrahan, Leroy J. Seymour, Anna Beckius, Donna Welter, Mandy Kastner, Valarie Ehrlich, Kristine Broge-Reynen, Mary Rodgers, Laura C. Michaelis, Lyndsey Runaas, Ehab L. Atallah, Sameem Abedin, Guru Subramanian Guru Murthy, Ravi Kishore Narra, Mary Fournogerakis, Jessica Schmitz, Andrea Viitala, Elizabeth Larsen, Amber Essenmacher, Gina George, Kim Johnston, Karen Sue Carlson, Nicole Held
Journal: Blood
Blood (2022) 140 (Supplement 1): 5083–5085.
https://doi.org/10.1182/blood-2022-159809
Published: 2022
Journal Articles

Neihulizumab (ALTB-168) in Patients with Steroid-Refractory Acute Graft-Versus-Host-Disease (SR-aGVHD) or Treatment-Refractory Acute Graft-Versus-Host-Disease (TR-aGVHD)

Sameem Abedin, Mehdi Hamadani, Shernan G Holtan, Gary J. Schiller, Molly Gallogly, Edmund K. Waller, Satyajit Kosuri, Sunil H Abhyankar, Sarah M. Anand, Mahasweta Gooptu, Iming Cho, Simona Reed, Shih-Yao Lin, Jesse W Hall, Paul J Martin
Journal: Blood
Blood (2022) 140 (Supplement 1): 10495–10497.
https://doi.org/10.1182/blood-2022-163027
Published: 2022
Journal Articles

A Phase I Study of Pevonedistat, Azacitidine and Venetoclax for Patients with Relapsed/Refractory Acute Myelogenous Leukemia (AML)

Guru Subramanian Guru Murthy, Scott H. Kaufmann, Aniko Szabo, Alexandra M. Harrington, Laura C. Michaelis, Sameem Abedin, Karen Carlson, Lyndsey Runaas, Walter L. Longo, Alexander Hinman, Sonia Maldonado-Schmidt, Althea Thomas, Arielle Baim, Mark R. Litzow, Ehab L. Atallah
Journal: Blood
Blood (2021) 138 (Supplement 1): 2347.
https://doi.org/10.1182/blood-2021-149351
Published: 2021
Journal Articles

Lintuzumab-Ac225 in Combination with CLAG-M Yields High MRD (-) Responses in R/R AML with Adverse Features: Interim Results of a Phase I Study

Sameem Abedin, Guru Subramanian Guru Murthy, Mehdi Hamadani, Laura C. Michaelis, Lyndsey Runaas, Karen Carlson, Ehab L. Atallah
Journal: Blood
Blood (2021) 138 (Supplement 1): 3414.
https://doi.org/10.1182/blood-2021-148746
Published: 2021
Journal Articles

Comparative Effectiveness of Venetoclax Combinations Vs Other Therapies Among Patients with Newly Diagnosed Acute Myeloid Leukemia: Results from the AML Real World Evidence (ARC) Initiative

Jacqueline S. Garcia, Ofir Wolach, Pankit Vachhani, Joshua F. Zeidner, Chetasi Talati, Daniel A. Pollyea, Catherine Lai, Yakir Moshe, Sameem Abedin, David Lavie, Tsila Zuckerman, Marin Xavier, Sangmin Lee, Wesleigh Edwards, Evan Chen, Cat N. Bui, Anders Svensson, Rebecca Burne, Steve Kye, Jessica Maitland, Esprit Ma, Melissa Montez, Moshe Grunspan, Aaron D Goldberg
Journal: Blood
Blood (2021) 138 (Supplement 1): 2328.
https://doi.org/10.1182/blood-2021-151285
Published: 2021
Journal Articles

Gilteritinib Can be Safely Combined with Atezolizumab for the Treatment of Relapsed or Refractory FLT3 -Mutated AML: Results of a Phase 1 Study

Jessica K. Altman, Bhavana Bhatnagar, Sameem Abedin, Amanda Przespolewski, Prapti A. Patel, Gary J. Schiller, Stanley Gill, Dhruva Patel, Linyi Fan, Ramon V. Tiu, Stephen A. Strickland
Journal: Blood
Blood (2021) 138 (Supplement 1): 2343.
https://doi.org/10.1182/blood-2021-150707
Published: 2021
Journal Articles

Real-World Management of Patients with Newly Diagnosed Acute Myeloid Leukemia Treated with Venetoclax-Based Regimens: Results from the AML Real World Evidence (ARC) Initiative

Pankit Vachhani, Ofir Wolach, Jacqueline S. Garcia, Joshua F. Zeidner, Chetasi Talati, Daniel A. Pollyea, Catherine Lai, Yakir Moshe, Sameem Abedin, David Lavie, Tsila Zuckerman, Marin Xavier, Sangmin Lee, Evan Chen, Wesleigh Edwards, Cat N. Bui, Anders Svensson, Steve Kye, Rebecca Burne, Jessica Maitland, Esprit Ma, Melissa Montez, Moshe Grunspan, Aaron D Goldberg
Journal: Blood
Blood (2021) 138 (Supplement 1): 1271.
https://doi.org/10.1182/blood-2021-151586
Published: 2021