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Shrikanta Chattopadhyay
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Journal Articles

TSC-100 and TSC-101 Demonstrate the Potential to Reduce Relapse Rates and Increase Relapse-Free Survival in Patients with AML, ALL, or MDS Undergoing Allogeneic HCT with Reduced Intensity Conditioning (RIC): Preliminary Results from the Phase 1 Alloha Trial

MHD Monzr M. Al Malki, Alla Keyzner, Uday Popat, Yi-Bin Chen, Hyung C Suh, Tania Jain, Melhem M. Solh, Anson Snow, Saar Gill, Lohith Gowda, Joseph Uberti, Erica Buonomo, Yun Wang, Nancy Nabilsi, Timothy White, Cuong Nguyen, Jim Murray, Gavin MacBeath, Chrystal Louis, Shrikanta Chattopadhyay, Michelle Matzko, Ran Reshef
Journal: Blood
Blood (2024) 144 (Supplement 1): 924.
https://doi.org/10.1182/blood-2024-201526
Published: 2024
Journal Articles

Initial Results of a Phase 1 Trial of TSC-100 and TSC-101, Engineered T Cell Therapies That Target Minor Histocompatibility Antigens to Prevent Relapse after Allogeneic Hematopoietic Cell Transplantation

Monzr M. Al Malki, Alla Keyzner, Hyung Chan Suh, Aasiya Matin, Erica Buonomo, Yun Wang, Nina Abelowitz, Jim Murray, Gavin Macbeath, Debora Barton, Shrikanta Chattopadhyay, Ran Reshef
Journal: Blood
Blood (2023) 142 (Supplement 1): 2090.
https://doi.org/10.1182/blood-2023-187355
Published: 2023
Journal Articles

Trial in Progress: A Phase 1 Umbrella Study of TCR-Engineered T Cells That Target HA-1 (TSC-100) and HA-2 (TSC-101) to Treat Residual Leukemia after Hematopoietic Cell Transplantation

Ran Reshef, Hyung C. Suh, Monzr M. Al Malki, Aasiya Matin, Ashish S Kothari, Allison Bell, Antoine J Boudot, Yun Wang, Nina Abelowitz, James Murray, Gavin Macbeath, Debora Barton, Shrikanta Chattopadhyay
Journal: Blood
Blood (2022) 140 (Supplement 1): 7468–7469.
https://doi.org/10.1182/blood-2022-167707
Published: 2022
Journal Articles

Discovery of TSC-101: A First-in-Class Natural HA-2-Specific TCR to Treat Leukemia Following Hematopoietic Stem Cell Transplant Therapy

Ribhu Nayar, Mollie M Jurewicz, Sonal Jangalwe, Hannah Bader, Kimberly M Cirelli, Andrew Basinski, Daniel Pollacksmith, Alexandra Luther, Cisem Karaca, Anna Labrozzi, Krista Daniel, Lisa Nip, Danielle Ramsdell, Amy Virbasius, Candace Perullo, Kenneth L Jahan, Sida Liao, Livio Dukaj, Alexandra Cristofaro, Shrikanta Chattopadhyay, Kenneth Olivier, Antoine J Boudot, Qikai Xu, Yifan Wang, Cagan Gurer, Gavin Macbeath
Journal: Blood
Blood (2021) 138 (Supplement 1): 1704.
https://doi.org/10.1182/blood-2021-151317
Published: 2021
Journal Articles

Product Characteristics and Multi-Arm Clinical Trial Design for TSC-100 and TSC-101, TCR-T Cells That Target Leukemia Following Hematopoietic Cell Transplantation

Shrikanta Chattopadhyay, Christopher Malcuit, Ryo Takeuchi, Emmett Hedblom, Warren Jaworowicz, Antoine J Boudot, Hannah Bader, James Murray, Gavin Macbeath
Journal: Blood
Blood (2021) 138 (Supplement 1): 3863.
https://doi.org/10.1182/blood-2021-153844
Published: 2021
Journal Articles

Osteoclast-Induced Immunosuppression Occurs through Dysregulation of Immune Checkpoint Axes in Multiple Myeloma

Kenta Mukaihara, MD PhD, Mattia D'Agostino, MD, Cristina Panaroni, PhD, Keertik Fulzele, PhD, Tomoaki Mori, MD PhD, Ka Tat Siu, PhD, Shrikanta Chattopadhyay, MBBS, Noopur Raje, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4382.
https://doi.org/10.1182/blood-2019-130462
Published: 2019
Journal Articles

Mature Osteoblasts Promote Multiple Myeloma Survival through Cell-Cell Contact and Immune Modulation Mechanisms

Keertik Fulzele, PhD, Cristina Panaroni, PhD, Kenta Mukaihara, MD PhD, Tomoaki Mori, MD PhD, Shrikanta Chattopadhyay, MBBS, Noopur S. Raje, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1802.
https://doi.org/10.1182/blood-2019-131213
Published: 2019
Journal Articles

Polyunsaturated Fatty Acid (PUFA) Signaling Induces Ferroptosis-Mediated Cell-Death in Multiple Myeloma

Cristina Panaroni, PhD, Keertik Fulzele, PhD, Rosemary Soucy, Cherrie Huang, Kenta Mukaihara, MD PhD, Shrikanta Chattopadhyay, MBBS, Noopur S. Raje, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3108.
https://doi.org/10.1182/blood-2019-131906
Published: 2019
Journal Articles

The Pleiotropic Immunosuppressive Role of Osteoclasts in Multiple Myeloma

Kenta Mukaihara, MD PhD, Ka Tat Siu, PhD, Cristina Panaroni, PhD, Keertik Fulzele, PhD, Rosemary Soucy, Cherrie Huang, Shrikanta Chattopadhyay, MBBS, Noopur Raje, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4447.
https://doi.org/10.1182/blood-2018-99-114922
Published: 2018
Journal Articles

Arachidonic Acid Induces Ferroptosis-Mediated Cell-Death in Multiple Myeloma

Cristina Panaroni, PhD, Keertik Fulzele, PhD, Rosemary Soucy, Ka Tat Siu, PhD, Kenta Mukaihara, MD PhD, Cherrie Huang, Shrikanta Chattopadhyay, MBBS, Noopur Raje, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4498.
https://doi.org/10.1182/blood-2018-99-118482
Published: 2018
Journal Articles

Overcoming MCL1 Resistance in Multiple Myeloma

Ka Tat Siu, PhD, Cherrie Huang, Cristina Panaroni, PhD, Kenta Mukaihara, MD PhD, Keertik Fulzele, PhD, Rosemary Soucy, Justin Cidado, PhD, Lisa Drew, PhD, Shrikanta Chattopadhyay, MBBS, Noopur Raje, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 472.
https://doi.org/10.1182/blood-2018-99-116377
Published: 2018
Journal Articles

Aldehyde Dehydrogenase 3a2 (Aldh3a2) Represents a Distinct Metabolic Vulnerability in MLL-AF9 AML Leukemia Initiating Cells

Rushdia Z. Yusuf, MBBS, MPH, Sanket S. Acharya, BA, MBS, Vionnie W.C. Yu, PhD, Borja Saez, PhD, Julien M Cobert, BA, John Doench, PhD, Lars Bullinger, MD, PhD, Dana S'aulis, BA, Dongjun Lee, PhD, Rahul Palchaudhuri, PhD, Akachimere C. Uzosike, Mildred Duvet, BA, David J. Logan, PhD, Sudeshna Das, PhD, Colleen M Cook, BA, Michael Churchill, BS, Elizabeth Scadden, BA, Gohar Warraich, Hao Liu, BA, Shrikanta Chattopadhyay, MD, Adam Brown, PhD, Stephen M. Sykes, PhD, David B. Sykes, MD, PhD, Francois Mercier, MD, Anne E. Carpenter, PhD, Scott A. Armstrong, MD, PhD, Matthew Vander Heiden, MD, PhD, Benjamin L. Ebert, Andrew L. Kung, MD, PhD, William B. Rizzo, MD, Siddhartha Mukherjee, MD, PhD, David T. Scadden, MD
Journal: Blood
Blood (2012) 120 (21): 208.
https://doi.org/10.1182/blood.V120.21.208.208
Published: 2012
Journal Articles

Niche-Based Screening Identifies Novel Small Molecules That Overcome Stromal Effects in Multiple Myeloma

Shrikanta Chattopadhyay, MBBS, Alison L. Stewart, PhD, Siddhartha Mukherjee, MD, PhD, Cherrie Huang, Kimberly A. Hartwell, PhD, Peter G. Miller, PhD, Leigh Carmody, PhD, Rushdia Z. Yusuf, MBBS, MPH, David B. Sykes, MD, PhD, Sonia Vallet, Loredana Santo, Diana D. Cirstea, MD, Teru Hideshima, MD, PhD, Vladimir Dancik, PhD, Jaime Cheah, PhD, Edmund Price, Abigail Bracha, PhD, Max Majireck, PhD, Mahmud Hussain, PhD, Shambhavi Singh, Nicola Tolliday, PhD, Malcolm A.S. Moore, D.Phil, Andrew M. Stern, PhD, Alykhan F Shamji, PhD, Benjamin L. Ebert, MD, PhD, Todd R. Golub, MD, Noopur Raje, MD, David T. Scadden, MD, Stuart L. Schreiber, PhD
Journal: Blood
Blood (2012) 120 (21): 571.
https://doi.org/10.1182/blood.V120.21.571.571
Published: 2012
Journal Articles

Distinct Metabolic Dependency of Normal and Leukemic Cells in a Mouse Model

Rushdia Z. Yusuf, MBBS, MPH, Sanket S. Acharya, BA, MBS, Vionnie Yu, PhD, Borja Saez, PhD, Mildred Duvet, Elizabeth Scadden, BA, Gohar Warraich, Clary Clish, PhD, Michael Churchill, BS, John Doench, PhD, David J. Logan, PhD, Colleen Cook, BA, Sudeshna Das, PhD, Adam Brown, PhD, Stephen M. Sykes, Shrikanta Chattopadhyay, MD, Anne E. Carpenter, PhD, Mathew Vander Heiden, MD, PhD, Scott A. Armstrong, MD, PhD, Siddhartha Mukherjee, MD, PhD, Benjamin L. Ebert, MD, D.Phil, David T. Scadden, MD
Journal: Blood
Blood (2011) 118 (21): 759.
https://doi.org/10.1182/blood.V118.21.759.759
Published: 2011
Journal Articles

Niche-Based Screening Reveals Leukemia Stem Cell Specific Therapeutics

Kimberly A. Hartwell, PhD, Peter G. Miller, PhD, Alison L. Stewart, PhD, Alissa R. Kahn, MD, David J. Logan, PhD, Joseph Negri, Mildred Duvet, Shrikanta Chattopadhyay, MD, Sebastian Shterental, Lisa P Chu, Jae Hung Shieh, PhD, Marcus Jaeraas, MD, Vladimir Dancik, PhD, Rajiv Narayan, PhD, Christina Huang, J Erika Haydu, Siddhartha Mukherjee, MD, PhD, Alykhan F Shamji, PhD, Nicola J Tolliday, PhD, Anne E. Carpenter, PhD, Stuart L. Schreiber, PhD, Andrew M. Stern, PhD, Malcolm AS Moore, D Phil, David T. Scadden, MD, Benjamin L. Ebert, MD, D.Phil, Todd R. Golub, MD
Journal: Blood
Blood (2011) 118 (21): 760.
https://doi.org/10.1182/blood.V118.21.760.760
Published: 2011