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Pierre Lao-Sirieix
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Journal Articles

Impact of chimeric antigen receptor (CAR) product cell phenotypes on clinical outcomes following treatment with obecabtagene autoleucel (obe-cel)

Free
Benjamin Simpson, Rehan Hussain, Mohammed Banani, Karamjeet Sandhu, Michael Bishop, Aaron Logan, Ping Wang, William Day, Claire Roddie, Pierre Lao-Sirieix
Journal: Blood
Blood (2025) 146 (Supplement 1): 33.
https://doi.org/10.1182/blood-2025-33
Published: 2025
Journal Articles

Treatment of pediatric patients (pts) with relapsed/refractory B-cell acute lymphoblastic leukemia (R/R B-ALL) with obecabtagene autoleucel (obe-cel), a CD19-directed chimeric antigen receptor (CAR) T-cell therapy: Preliminary findings from the Phase Ib/II CATULUS trial

Free
Sara Ghorashian, Michael Pulsipher, Juliana Silva, Alba Rubio-San-Simón, Amanda Lipsitt, Denise Bonney, Cristina Díaz-de-Heredia, Geoff Shenton, Justin Shang, Kapil Saxena, Wolfram Brugger, Pierre Lao-Sirieix, Shannon Maude
Journal: Blood
Blood (2025) 146 (Supplement 1): 3337.
https://doi.org/10.1182/blood-2025-3337
Published: 2025
Journal Articles

Evaluation of commercially available chimeric antigen receptor (CAR) detection reagents for monitoring of CAR T-cell (CAR T) expansion and persistence in patients (pts) treated with obecabtagene autoleucel (obe-cel)

Free
Rehan Hussain, Yousef Farag, Anish Patel, Hrishikesh Srinagesh, Lori Muffly, Bita Sahaf, David Miklos, Mathieu Ferrari, William Day, Pierre Lao-Sirieix
Journal: Blood
Blood (2025) 146 (Supplement 1): 2367.
https://doi.org/10.1182/blood-2025-2367
Published: 2025
Journal Articles

Chimeric antigen receptor (CAR) T-cell persistence at month 3 predicts clinical outcomes in adult patients with relapsed/refractory B-cell acute lymphoblastic leukemia (R/R B-ALL) treated with obecabtagene autoleucel (obe-cel)

Free
Claire Roddie, Jae Park, Eleni Tholouli, Karamjeet Sandhu, Paul Shaughnessy, Pere Barba, Manuel Guerreiro, Deborah Yallop, Aaron Logan, Mehrdad Abedi, Pierre Lao-Sirieix, Ping Wang, Wolfram Brugger, Bijal Shah, Anthony Hunter, Daniel Deangelo, Elias Jabbour
Journal: Blood
Blood (2025) 146 (Supplement 1): 5118.
https://doi.org/10.1182/blood-2025-5118
Published: 2025
Journal Articles

Obecabtagene autoleucel (obe-cel) for Adult Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia (R/R B-ALL) in the Open-Label, Multi-Center, Global, Single-Arm, Phase Ib/II FELIX Study: The Impact of Bridging Therapies on CAR T-Cell Expansion and Persistence

Free
Jae H. Park, Elias Jabbour, Paul Shaughnessy, Aaron C. Logan, Karamjeet S Sandhu, Mehrdad Abedi, Bijal D Shah, Michael R Bishop, Daniel J. DeAngelo, Pierre Lao-Sirieix, Wolfram Brugger, Martin A Pule, Justin Shang, Claire Roddie
Journal: Blood
Blood (2024) 144 (Supplement 1): 3458.
https://doi.org/10.1182/blood-2024-201514
Published: 2024
Journal Articles

Obecabtagene autoleucel (obe-cel) for Adult Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia (R/R B-ALL): Deep Molecular Remission May Predict Better Outcomes

Free
Elias Jabbour, Jae H. Park, Paul Shaughnessy, Aaron C. Logan, Karamjeet S Sandhu, Mehrdad Abedi, Bijal D Shah, Michael R Bishop, Daniel J. DeAngelo, Pierre Lao-Sirieix, Wolfram Brugger, Martin A Pule, Yiyun Zhang, Claire Roddie
Journal: Blood
Blood (2024) 144 (Supplement 1): 963.
https://doi.org/10.1182/blood-2024-194508
Published: 2024
Journal Articles

Obecabtagene Autoleucel (obe-cel, AUTO1) for Relapsed/Refractory Adult B-cell Acute Lymphoblastic Leukemia (R/R B-ALL): Pooled Analysis of the Ongoing FELIX Phase Ib/II Study

Free
Claire Roddie, Karamjeet S. Sandhu, Eleni Tholouli, Paul Shaughnessy, Pere Barba, Manuel Guerreiro, Michael R. Bishop, Jean A. Yared, Armin Ghobadi, Deborah Yallop, Aaron C. Logan, Amer M. Beitinjaneh, Jeremy M. Pantin, Martha Arellano, Sridhar Chaganti, Ram Malladi, Tobias Menne, Virginia Escamilla Gómez, Katharine Hodby, Krishna Gundabolu, Luke Mountjoy, Kristen M. O'Dwyer, Sameem Abedin, Hassan Alkhateeb, Bijal D. Shah, Pierre Lao-Sirieix, Gianfranco Pittari, Kapil Saxena, Yiyun Zhang, Wolfram Brugger, Martin A. Pule, Jae H. Park, Daniel J. DeAngelo, Elias Jabbour
Journal: Blood
Blood (2023) 142 (Supplement 1): 222.
https://doi.org/10.1182/blood-2023-179454
Published: 2023