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Jessica K. Altman
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Journal Articles

A Phase 1a/b Trial of Luxeptinib (CG-806) in Patients with Relapsed/Refractory B-Cell Malignancies or Acute Myeloid Leukemia and Evaluation of New G3 Formulation

Aaron D. Goldberg, Felipe Samaniego, Maro Ohanian, Paul B. Koller, Namrata Sonia Chandhok, Ahad A. Sadiq, Daruka Mahadevan, Mohamad A. Cherry, Jessica K. Altman, John M. Burke, Michael Z. Koontz, J. C. C Villasboas, Ben K. Tomlinson, Laura E. Finn, Erin G Reid, Jason Melear, Victor Priego, Patrick Cobb, Elizabeth Heritage Cull, Paul Conkling, David Cosgrove, Lindsey E. Roeker, Eric Tam, Donna Nguyen Haney, Jia Hu, Ranjeet Sinha, Nawazish Khan, William G. Rice, Rafael Bejar
Journal: Blood
Blood (2023) 142 (Supplement 1): 5953.
https://doi.org/10.1182/blood-2023-181151
Published: 2023
Journal Articles

Characteristics and Outcomes of Younger Adult Patients (Pts) with Myelodysplastic Syndromes (MDS): A Multicenter Retrospective Study

Yasmin Abaza, Zhuoer Xie, Madelyn Burkart, Talha Badar, Pinkal Desai, Rory M. Shallis, Anand Ashwin Patel, Adam Cohen-Nowak, Timothy S. Oh, Chelsea Walker, Neela Easwar, Tariq Kewan, Joseph Cannova, Kirsten Bell-Burdett, Najla H Al Ali, David A Sallman, Gail J. Roboz, Hetty E. Carraway, Amer M. Zeidan, Mrinal M. Patnaik, Jessica K. Altman, Rami S. Komrokji
Journal: Blood
Blood (2023) 142 (Supplement 1): 3232.
https://doi.org/10.1182/blood-2023-188328
Published: 2023
Journal Articles

Financial Toxicity and Quality of Life in Patients Taking Oral Therapy for Hematologic Malignancies

Max F. Kelsten, Scott A. Wu, Previn Ganesan, William B. Pearse, Jessica K. Altman, Sheetal Kircher
Journal: Blood
Blood (2023) 142 (Supplement 1): 7413.
https://doi.org/10.1182/blood-2023-173588
Published: 2023
Journal Articles

Frontline Aspacytarabine with Venetoclax for Older/Unfit Patients with Acute Myeloid Leukemia: Preliminary Results of a Phase 1 Study

Jessica K. Altman, Yasmin Abaza, Michael Keng, Abhishek Maiti, Jamie Koprivnikar, Shoshi Tessler, Chen Blumberg, Liat Flaishon, Ruth Ben Yakar
Journal: Blood
Blood (2023) 142 (Supplement 1): 5970.
https://doi.org/10.1182/blood-2023-185694
Published: 2023
Journal Articles

Individual-Level Social Determinants of Health (SDOH) Measures and Treatment Complications in Acute Leukemia

Eshana Shah, Ana Maria Avila Rodriguez, Jerry W Luo, Joanna Cwykiel, Tasha Chasson, Elizabeth Raigoza, Alexander Bratslavsky, Peter Doukas, Reanna Williams, Christa Jackowicz, Hyein Lee, Talha Khan, Kimberly Webb, Yasmin Abaza, Jessica K. Altman, Betina Yanez, John Quigley, Carlos Galvez, Shira N. Dinner, Kim Johnson, Madelyn Burkart, Irum Khan
Journal: Blood
Blood (2023) 142 (Supplement 1): 374.
https://doi.org/10.1182/blood-2023-189024
Published: 2023
Journal Articles

Older Adults with Acute Myeloid Leukemia (AML) Experience Improvement in Health-Related Quality of Life (HRQoL) Scores with Intensive Therapy: Prospective Study from ECOG-ACRIN (EA) E2906 Phase 3 Trial

James M. Foran, Li Chen, Selina M Luger, Zhuoxin Sun, Heidi Klepin, David F. Claxton, Hillard M. Lazarus, Jacob M. Rowe, Jessica K. Altman, Aref Al-Kali, Hong Zheng, Keith W Pratz, Edward R. Broun, Bayard L Powell, Kristen M. O'Dwyer, Yishai Ofran, John E. Godwin, Mark R. Litzow, Martin S. Tallman, Lynne Wagner
Journal: Blood
Blood (2023) 142 (Supplement 1): 594.
https://doi.org/10.1182/blood-2023-189734
Published: 2023
Journal Articles

The Impact of Air Pollutants on a Chicagoland Cohort of Patients with Acute Myeloid Leukemia

Andrew Palmer, Garth Rauscher, Ivy Abraham, Madelyn Burkart, Ami Dave, Nepheli Raptis, Ahmed Aleem, Vedavyas Gannamani, Amani Erra, Sarah Monick, Carlos Galvez, Melissa L. Larson, Maryam Zia, Stephanie B. Tsai, Jessica K. Altman, Wendy Stock, Irum Khan, Anand Ashwin Patel
Journal: Blood
Blood (2023) 142 (Supplement 1): 3806.
https://doi.org/10.1182/blood-2023-178265
Published: 2023
Journal Articles

Pivekimab Sunirine (PVEK, IMGN632), a CD123-Targeting Antibody-Drug Conjugate, in Combination with Azacitidine and Venetoclax in Patients with Newly Diagnosed Acute Myeloid Leukemia

Naval Daver, Pau Montesinos, Jessica K. Altman, Eunice S. Wang, Giovanni Martinelli, Gail J. Roboz, Kebede Begna, Paresh Vyas, Monia Lunghi, Uwe Platzbecker, Patrick W. Burke, Roland B. Walter, Anjali S. Advani, Sylvain Garciaz, Lauris Gastaud, David A Sallman, Naveen Pemmaraju, Laura Torres, Yasmin Abaza, Onyee Chan, Hagop M. Kantarjian, Benjamin Oshrine, Yining Du, Kara Malcolm, Kendra Sweet
Journal: Blood
Blood (2023) 142 (Supplement 1): 2906.
https://doi.org/10.1182/blood-2023-173413
Published: 2023
Journal Articles

PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371

Hongxia Chen, Yunpeng Bai, Michihiro Kobayashi, Shiyu Xiao, Wenjie Cai, Sergio Barajas, Sisi Chen, Jinmin Miao, Frederick Nguele Meke, Sasidhar Vemula, James P. Ropa, James M. Croop, H. Scott Boswell, Jun Wan, Yuzhi Jia, Huiping Liu, Loretta S. Li, Jessica K. Altman, Elizabeth A. Eklund, Peng Ji, Wei Tong, Hamid Band, Danny T. Huang, Leonidas C. Platanias, Zhong-Yin Zhang, Yan Liu
Journal: Blood
Blood (2023) 141 (3): 244–259.
https://doi.org/10.1182/blood.2022016580
Published: 2023
Includes: Supplemental data
Journal Articles

Long-term outcomes in patients with relapsed or refractory hairy cell leukemia treated with vemurafenib monotherapy

Clinical Trials & Observations
Shivani Handa, Jeong-Ok Lee, Andriy Derkach, Richard M. Stone, Alan Saven, Jessica K. Altman, Michael R. Grever, Kanti R. Rai, Madhulika Shukla, Shreya Vemuri, Skye Montoya, Justin Taylor, Omar Abdel-Wahab, Martin S. Tallman, Jae H. Park
Journal: Blood
Blood (2022) 140 (25): 2663–2671.
https://doi.org/10.1182/blood.2022016183
Published: 2022
Journal Articles

A Phase 1a/b Dose Escalation Study of the FLT3/BTK Inhibitor Luxeptinib (CG-806) in Patients with Relapsed or Refractory Acute Myeloid Leukemia

Aaron D Goldberg, Maro Ohanian, Paul B. Koller, Mohamad Cherry, Jessica K. Altman, Benjamin Tomlinson, Namrata Sonia Chandhok, Donna Nguyen Haney, Jia Hu, Ranjeet Kumar Sinha, William G Rice, Rafael Bejar
Journal: Blood
Blood (2022) 140 (Supplement 1): 6220–6221.
https://doi.org/10.1182/blood-2022-167759
Published: 2022
Journal Articles

A Simplified Patient Care Strategy to Decrease Early Deaths in Acute Promyelocytic Leukemia (APL): Results of the ECOG-ACRIN EA9131 Trial

Anand P. Jillella, Sandra J. Lee, Jessica K. Altman, Selina M. Luger, Martin S. Tallman, James M. Foran, Lisa Y. Law, Locke J. Bryan, Abdallah Abou Zahr, Kebede Begna, Alexander Perl, Joseph Vadakara, Federico Sanchez, Raymond C. Bergan, Michael J. Fisch, Ruth C. Carlos, Lynne I. Wagner, Mark R. Litzow, Vamsi K. Kota
Journal: Blood
Blood (2022) 140 (Supplement 1): 1011–1013.
https://doi.org/10.1182/blood-2022-163436
Published: 2022
Journal Articles

Multi-Omic Single-Cell Sequencing Reveals Genetic and Immunophenotypic Clonal Selection in Patients With FLT3-Mutated AML Treated With Gilteritinib/Venetoclax

Vanessa E. Kennedy, Cheryl Peretz, Paul Lee, Brenda Chyla, Yan Sun, Monique Dail, Jason Hill, Elaine Tran, Andrew Koh, Jessica K. Altman, Naval Daver, Mark J. Levis, James McCloskey, Alexander Perl, Catherine Smith
Journal: Blood
Blood (2022) 140 (Supplement 1): 2244–2246.
https://doi.org/10.1182/blood-2022-160304
Published: 2022
Journal Articles

Synthetic Lipid Nanoparticles Actively Target Acute Myeloid Leukemia (AML) Cells and Induce Ferroptosis through Decreased Expression of Glutathione Peroxidase 4

Adam Yuh Lin, Jonathan Scott Rink, Eva Yang, Sara Small, Fransheska Serrano, Yasmin Abaza, Jessica K. Altman, Leonidas C. Platanias, Colby Shad Thaxton, Leo I. Gordon
Journal: Blood
Blood (2022) 140 (Supplement 1): 5967–5968.
https://doi.org/10.1182/blood-2022-168154
Published: 2022
Journal Articles

A Multi-Center Phase Ib Trial of the Histone Deactylase Inhibitor (HDACi) Entinostat in Combination with Anti-PD1 Antibody Pembrolizumab in Patients with Refractory/Relapsed Myelodysplastic Syndromes (RR-MDS) or Oligoblastic Acute Myeloid Leukemia (RR-AML) after Hypomethylating Agent (HMA) Failure

Jan Philipp Bewersdorf, Rory Michael Shallis, Elad Sharon, Anne Caldwell, Wei Wei, Abdulraheem Yacoub, Yazan F. Madanat, Joshua F. Zeidner, Jessica K. Altman, Olatoyosi Odenike, Swaroopa Yerrabothala, Tibor Kovacsovics, Nikolai A. Podoltsev, Stephanie Halene, Richard F. Little, Richard Piekarz, Steven D. Gore, Tae Kon Kim, Amer M. Zeidan
Journal: Blood
Blood (2022) 140 (Supplement 1): 9084–9086.
https://doi.org/10.1182/blood-2022-158626
Published: 2022
Journal Articles

A Phase 1, Open-Label, Safety, Tolerability, and Efficacy Study of NC525 in Subjects with Advanced Myeloid Neoplasms

Nicholas Short, Tae Kon Kim, Rustin Lovewell, Elizabeth A. Griffiths, Hetty E. Carraway, Stephanie Zeidan, Elizabeth Knowles, Megan Nelson, Jahangheer Shaik, Chelsea Zhou, Emilia Alina Barbu, Zachary Cusumano, Subhadip Kundu, Sasan Sharee, Ron Copeland, Dallas Flies, Solomon Langermann, Han Myint, Jessica K. Altman, Farhad Ravandi
Journal: Blood
Blood (2022) 140 (Supplement 1): 9078–9079.
https://doi.org/10.1182/blood-2022-167349
Published: 2022
Journal Articles

Venetoclax (VEN) Plus Intensive Chemotherapy (IC) with FLAG-IDA in Patients (Pts) with Newly Diagnosed (ND) and Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)

Yasmin Abaza, Talha Khan, Shira Dinner, Olga Frankfurt, Jessica K. Altman
Journal: Blood
Blood (2022) 140 (Supplement 1): 9036–9038.
https://doi.org/10.1182/blood-2022-168437
Published: 2022
Journal Articles

Measures of Structural Racism Predict ICU Admission Following Intensive Chemotherapy for AML

Ivy Abraham, Garth Rauscher, Anand Ashwin Patel, Sarah Monick, Madelyn Burkhart, Eshana Shah, Ami Dave, Matthew Kroll, Stephanie B. Tsai, Stephanie Berg, Amani Erra, Vedavyas Gannamani, Maryam Zia, Melissa L. Larson, Wendy Stock, Jessica K. Altman, Irum Khan
Journal: Blood
Blood (2022) 140 (Supplement 1): 6061–6063.
https://doi.org/10.1182/blood-2022-166907
Published: 2022
Journal Articles

Update on a Phase 1/2 First-in-Human Study of the Menin-KMT2A (MLL) Inhibitor Ziftomenib (KO-539) in Patients with Relapsed or Refractory Acute Myeloid Leukemia

Harry P. Erba, Amir T. Fathi, Ghayas C. Issa, Jessica K. Altman, Pau Montesinos, Mrinal M. Patnaik, James M. Foran, Stephane De Botton, Maria R. Baer, Gary J. Schiller, Roland B. Walter, Marina Kremyanskaya, Kristen M. Pettit, Stephen A Strickland, Blake Tomkinson, Marilyn Tabachri, Mollie Leoni, Stephen Dale, Eunice S. Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 153–156.
https://doi.org/10.1182/blood-2022-167412
Published: 2022
Journal Articles

Broad Activity for the Pivekimab Sunirine (PVEK, IMGN632), Azacitidine, and Venetoclax Triplet in High-Risk Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML)

Naval Daver, Pau Montesinos, Ahmed Aribi, Giovanni Marconi, Jessica K. Altman, Eunice S. Wang, Gail J. Roboz, Patrick W. Burke, Gianluca Gaidano, Roland B. Walter, Xavier Thomas, Deepa Jeyakumar, Daniel J. DeAngelo, Harry P. Erba, Elisabetta Todisco, Kebede H. Begna, Anjali Advani, Lauris Gastaud, Adolfo De La Fuente, Antonio Curti, Lourdes M. Mendez, Paresh Vyas, Nicolas Boissel, Norbert Vey, Christian Recher, Thomas Longval, Uwe Platzbecker, Silke Kapp-Schwoerer, Christoph Schliemann, Marina Konopleva, Laura Torres, David A. Sallman, Guido Marcucci, Naveen Pemmaraju, Giovanni Martinelli, Hagop Kantarjian, Callum M Sloss, Kara E Malcolm, Patrick A Zweidler-McKay, Kendra Sweet
Journal: Blood
Blood (2022) 140 (Supplement 1): 145–149.
https://doi.org/10.1182/blood-2022-158030
Published: 2022