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Journal Articles

Rapid Degradation of mDia2 Protein during Terminal Erythropoiesis Via an In Vivo Aid System: An Alternative Approach for Loss-of-Function Studies

Kehan Ren, Zongjun Xia, Ermin Li, Xu Han, Peng Ji
Journal: Blood
Blood (2023) 142 (Supplement 1): 2443.
https://doi.org/10.1182/blood-2023-178268
Published: 2023
Journal Articles

PPIL2 Is a Target of the JAK2-STAT5 Pathway and Mediates p53 Polyubiquitination and Degradation

Pan Wang, Xu Han, Kehan Ren, Ermin Li, Honghao Bi, Inci Aydemir, Peng Ji
Journal: Blood
Blood (2023) 142 (Supplement 1): 4515.
https://doi.org/10.1182/blood-2023-177677
Published: 2023
Journal Articles

Spatial Mapping Reveals Distinct Erythroid Niches in Mice and Humans during Development and Stress

Xu Han, Kehan Ren, Pan Wang, Honghao Bi, Inci Aydemir, Ermin Li, Peng Ji
Journal: Blood
Blood (2023) 142 (Supplement 1): 140.
https://doi.org/10.1182/blood-2023-181272
Published: 2023
Journal Articles

DDX41 Dissolves G-Quadruplexes to Maintain Erythroid Genomic Integrity and Prevent Genome DNA Leakage-Induced Cgas Activation

Honghao Bi, Pan Wang, Wen Wang, Kehan Ren, Elizabeth Bartom, Xu Han, Ermin Li, Peng Ji
Journal: Blood
Blood (2023) 142 (Supplement 1): 949.
https://doi.org/10.1182/blood-2023-177765
Published: 2023
Journal Articles

Bone-derived C-terminal FGF23 cleaved peptides increase iron availability in acute inflammation

Guillaume Courbon, Jane Joy Thomas, Marta Martinez-Calle, Xueyan Wang, Jadeah Spindler, John Von Drasek, Bridget Hunt-Tobey, Rupal Mehta, Tamara Isakova, Wenhan Chang, John W. M. Creemers, Peng Ji, Aline Martin, Valentin David
Journal: Blood
Blood (2023) 142 (1): 106–118.
https://doi.org/10.1182/blood.2022018475
Published: 2023
Includes: Multimedia, Supplemental data
Journal Articles

PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371

Hongxia Chen, Yunpeng Bai, Michihiro Kobayashi, Shiyu Xiao, Wenjie Cai, Sergio Barajas, Sisi Chen, Jinmin Miao, Frederick Nguele Meke, Sasidhar Vemula, James P. Ropa, James M. Croop, H. Scott Boswell, Jun Wan, Yuzhi Jia, Huiping Liu, Loretta S. Li, Jessica K. Altman, Elizabeth A. Eklund, Peng Ji, Wei Tong, Hamid Band, Danny T. Huang, Leonidas C. Platanias, Zhong-Yin Zhang, Yan Liu
Journal: Blood
Blood (2023) 141 (3): 244–259.
https://doi.org/10.1182/blood.2022016580
Published: 2023
Includes: Supplemental data
Journal Articles

Serum Response Factor Is Critical for Terminal Erythropoiesis

Kehan Ren, Ermin Li, Zongjun Xia, Peng Ji
Journal: Blood
Blood (2022) 140 (Supplement 1): 5301.
https://doi.org/10.1182/blood-2022-160169
Published: 2022
Journal Articles

Nuclear Opening and Histone Release Are Essential for Nuclear but Not Chromatin Condensation during Terminal Erythropoiesis

Honghao Bi, Yijie Liu, Dongmei Wang, Ye Hou, Yue Feng, Peng Ji
Journal: Blood
Blood (2021) 138 (Supplement 1): 287.
https://doi.org/10.1182/blood-2021-150794
Published: 2021
Journal Articles

Gasdermin D Mediates Inflammation-Driven Pathogenesis of the Myelodysplastic Syndromes

Kehan Ren, Yang Mei, Yijie Liu, Xu Han, Ermin Li, Honghao Bi, Peng Ji
Journal: Blood
Blood (2021) 138 (Supplement 1): 2587.
https://doi.org/10.1182/blood-2021-149340
Published: 2021
Journal Articles

Membrane skeleton modulates erythroid proteome remodeling and organelle clearance

Yijie Liu, Yang Mei, Xu Han, Farida V. Korobova, Miguel A. Prado, Jing Yang, Zhangli Peng, Joao A. Paulo, Steven P. Gygi, Daniel Finley, Peng Ji
Journal: Blood
Blood (2021) 137 (3): 398–409.
https://doi.org/10.1182/blood.2020006673
Published: 2021
Includes: Multimedia, Supplemental data
Journal Articles

Targeting Pleckstrin-2 for the Treatment of Myeloproliferative Neoplasms

Xu Han, PhD, Yang Mei, Gary Schiltz, Rama Mishra, Atul Jain, Peng Ji, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10–11.
https://doi.org/10.1182/blood-2020-137051
Published: 2020
Journal Articles

IL-6 Deficiency Reverses Leukemic Transformation in an MDS Mouse Model

Yang Mei, PhD, Yijie Liu, PhD, Xu Han, PhD, Jing Yang, PhD, Peng Ji, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 36.
https://doi.org/10.1182/blood-2020-137026
Published: 2020
Journal Articles

Formin Links Erythroid Cytoskeleton to Organelle Clearance through Escrt-III Complex during Reticulocyte Maturation

Yijie Liu, PhD, Haiyan Bao, MD, Yang Mei, PhD, Xu Han, PhD, Peng Ji, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 151.
https://doi.org/10.1182/blood-2019-125157
Published: 2019
Journal Articles

A Dynamic Motility Mechanism for Reticulocyte Enucleation and Maturation

Yijie Liu, PhD, Yang Mei, PhD, Xu Han, PhD, Peng Ji, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2329.
https://doi.org/10.1182/blood-2018-99-116499
Published: 2018
Journal Articles

Alisertib (MLN8237), an Oral Selective Inhibitor of Aurora Kinase a, Has Clinical Activity and Restores GATA1 Expression in Patients with Myelofibrosis

Naseema Gangat, MBBS, Brady Lee Stein, MD, Christian Marinaccio, Ronan Swords, MD PhD, Justin M. Watts, MD, Sandeep Gurbuxani, Olga Frankfurt, MD, Jessica K. Altman, MD, Jeremy Q. Wen, MD PhD, Noushin Farnoud, PhD, Christopher Famulare, MS, Akshar Patel, BA, Roberto Tapia, BS, Amy Handlogten, Yvonne Trang Dinh, BS, Kristen Englund, Shradha Patel, Juan Carlos Nobrega, Dalissa Tejera, MSN, Amber Thomassen, Harald Stein, MD PhD Dr. h.c., Juehua Gao, MD PhD, Peng Ji, MDPhD, Raajit K. Rampal, MD PhD, Francis J. Giles, MD FRCPI, FRCPath, Ayalew Tefferi, MD, John D. Crispino, PhD MBA
Journal: Blood
Blood (2018) 132 (Supplement 1): 688.
https://doi.org/10.1182/blood-2018-99-110381
Published: 2018
Journal Articles

USP22 deficiency leads to myeloid leukemia upon oncogenic Kras activation through a PU.1-dependent mechanism

Johanna Melo-Cardenas, Yuanming Xu, Juncheng Wei, Can Tan, Sinyi Kong, Beixue Gao, Elena Montauti, Gina Kirsammer, Jonathan D. Licht, Jindan Yu, Peng Ji, John D. Crispino, Deyu Fang
Journal: Blood
Blood (2018) 132 (4): 423–434.
https://doi.org/10.1182/blood-2017-10-811760
Published: 2018
Includes: Supplemental data
Journal Articles

Diaphanous-Related Formin Protein mDia2 Regulates Hematopoietic Stem and Progenitor Cell Functions through Srf-Integrins Pathway

Yang Mei, PhD, Baobing Zhao, PhD, Jingxin Zhang, PhD, Xu Han, PhD, Jing Yang, Peng Ji, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2421.
https://doi.org/10.1182/blood.V130.Suppl_1.2421.2421
Published: 2017
Journal Articles

Role of Activated Pleckstrin-2 and Down-Stream Effects on Ineffective Erythropoiesis in β-Thalassemic Mice

Maria Feola, BSc, MSc, Andrea Zamperone, PhD, Weili Bao, MS, Tenzin Choesang, MS, Huihui Li, MS, Guiyuan Li, MD, Shilpa M. Hattangadi, MD, Christopher E. Mason, PhD, Peng Ji, MD PhD, Antonia Follenzi, MD PhD, Yelena Ginzburg
Journal: Blood
Blood (2016) 128 (22): 1011.
https://doi.org/10.1182/blood.V128.22.1011.1011
Published: 2016
Journal Articles

Pleckstrin-2 Plays an Essential Role in the Pathogenesis of JAK2 V617F -Induced Myeloproliferative Neoplasms

Baobing Zhao, PhD, Yang Mei, PhD, Ronen Sumagin, PhD, Jing Yang, Chelsea Thorsheim, Liang Zhao, PhD, Timothy J. Stalker, PhD, Jeremy Q. Wen, John Crispino, PhD MBA, Charles S. Abrams, MD, Peng Ji, MD PhD
Journal: Blood
Blood (2016) 128 (22): 798.
https://doi.org/10.1182/blood.V128.22.798.798
Published: 2016
Journal Articles

Dual Deficiency of mDia1 and Mir-146a in an Age-Related Inflammatory Bone Marrow Microenvironment Induces Ineffective Erythropoiesis in Del(5q) MDS

Yang Mei, PhD, Ashley Basiorka, Baobing Zhao, PhD, Jing Yang, Alan F List, MD, Peng Ji, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3146.
https://doi.org/10.1182/blood.V128.22.3146.3146
Published: 2016