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Elizabeth A. Eklund
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Journal Articles

PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371

Hongxia Chen, Yunpeng Bai, Michihiro Kobayashi, Shiyu Xiao, Wenjie Cai, Sergio Barajas, Sisi Chen, Jinmin Miao, Frederick Nguele Meke, Sasidhar Vemula, James P. Ropa, James M. Croop, H. Scott Boswell, Jun Wan, Yuzhi Jia, Huiping Liu, Loretta S. Li, Jessica K. Altman, Elizabeth A. Eklund, Peng Ji, Wei Tong, Hamid Band, Danny T. Huang, Leonidas C. Platanias, Zhong-Yin Zhang, Yan Liu
Journal: Blood
Blood (2023) 141 (3): 244–259.
https://doi.org/10.1182/blood.2022016580
Published: 2023
Includes: Supplemental data
Journal Articles

Dynamin-2 Deficiency Causes Neutropenia and Dysplastic Bone Marrow Changes in an Age and Sex Dependent Manner in Mice

Alexander Willis, Seth J. Corey, Carlos A. Murga-Zamalloa, Saman Karimi, Karam Khaddour, Elizabeth A. Eklund, Yolande Chen
Journal: Blood
Blood (2021) 138 (Supplement 1): 992.
https://doi.org/10.1182/blood-2021-154010
Published: 2021
Journal Articles

Gene Expression Analysis of CML Patients across the Age Spectrum

Minyoung Youn, Stephanie M. Smith, Alex Gia Lee, Hee-Don Chae, Elizabeth Spiteri, Jason Erdmann, Ilana Galperin, Lara C. Murphy, Michele Donato, Parveen Abidi, Henrique Bittencourt, Norman J. Lacayo, Gary Dahl, Catherine Aftandilian, Kara L. Davis, Jairo A. Matthews, Steven M. Kornblau, Min Huang, Nathan Sumarsono, Michele Redell, Cecilia H. Fu, I-Ming L Chen, Todd A. Alonzo, Elizabeth A. Eklund, Jason Gotlib, Purvesh Khatri, Alejandro Sweet-Cordero, Nobuko Hijiya, Kathleen M. Sakamoto
Journal: Blood
Blood (2021) 138 (Supplement 1): 1473.
https://doi.org/10.1182/blood-2021-148701
Published: 2021
Journal Articles

Comparison of the Transcriptomic Signatures in Pediatric and Adult CML

Minyoung Youn, PhD, Hee-Don Chae, PhD, Stephanie M. Smith, MD, Alex Gia Lee, PhD, Lara C. Murphy, MD, Michele Donato, PhD, Alejandro Sweet-Cordero, Parveen Abidi, PhD, Henrique Bittencourt, MD PhD, Norman J. Lacayo, MD, Gary Dahl, Catherine Aftandilian, MD, Kara L Davis, DO, Jairo A. Matthews, Steven M. Kornblau, MD, Min Huang, PhD, Nathan Sumarsono, BS, Michele Redell, MD, Cecilia H. Fu, MD, I-Ming L Chen, Todd A. Alonzo, PhD, Elizabeth A. Eklund, MD, Jason Gotlib, MD MS, Purvesh Khatri, PhD, Nobuko Hijiya, MD, Kathleen M. Sakamoto, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39–40.
https://doi.org/10.1182/blood-2020-142270
Published: 2020
Journal Articles

Identification and targeting of novel CDK9 complexes in acute myeloid leukemia

Elspeth M. Beauchamp, Sameem M. Abedin, Sara G. Radecki, Mariafausta Fischietti, Ahmet Dirim Arslan, Gavin T. Blyth, Angela Yang, Connor Lantz, Alissa Nelson, Young Ah Goo, Imo Akpan, Elizabeth A. Eklund, Olga Frankfurt, Eleanor N. Fish, Paul M. Thomas, Jessica K. Altman, Leonidas C. Platanias
Journal: Blood
Blood (2019) 133 (11): 1171–1185.
https://doi.org/10.1182/blood-2018-08-870089
Published: 2019
Includes: Supplemental data
Journal Articles

Comparison of the Transcriptomic Signature of Pediatric Vs. Adult CML and Normal Bone Marrow Stem Cells

Hee-Don Chae, PhD, Lara C. Murphy, MD, Michele Donato, PhD, Alex G. Lee, PhD, E. Alejandro Sweet-Cordero, MD PhD, Parveen Abidi, PhD, Henrique Bittencourt, MD PhD, Norman J. Lacayo, MD, Gary Van Houten Dahl, MD, Catherine Aftandilian, MD, Kara L. Davis, DO, Min Huang, PhD, Nathan Sumarsono, BS, Michele Redell, MD PhD, Cecilia H. Fu, MD, I-Ming L. Chen, DVM, MS, Todd A Alonzo, PhD, Elizabeth A. Eklund, MD, Jason R. Gotlib, MD MS, Purvesh Khatri, PhD, Nobuko Hijiya, MD, Kathleen M. Sakamoto, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4246.
https://doi.org/10.1182/blood-2018-99-119974
Published: 2018
Journal Articles

Dynamins 2 and 3 Are Required for Human Megakaryocytes Directional Migration

Praveen K Suraneni, PhD, Seth J. Corey, MD, Michael Hession, BS, Rameez Ishaq, Arinola Awomolo, Shirin Hasan, PhD, Najet Debili, PhD, John D. Crispino, PhD MBA, Elizabeth A. Eklund, MD, Yolande Chen, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2429.
https://doi.org/10.1182/blood-2018-99-118782
Published: 2018
Journal Articles

Tumor Suppressor, NORE1A (RASSF5) , Is an Icsbp-Dependent Inhibitor of Aberrant Stress Granulopoiesis

Olatundun Williams, MD, Elizabeth Hjort, PhD, Ling Bei, MD, Liping Hu, PhD, Elizabeth A. Eklund, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4175.
https://doi.org/10.1182/blood.V130.Suppl_1.4175.4175
Published: 2017
Journal Articles

Bcr-Abl Represses IRF8 Gene Transcription in a Stat5-Dependent Manner

Elizabeth Hjort, Weiqi Huang, PhD, Elizabeth A. Eklund, MD
Journal: Blood
Blood (2012) 120 (21): 3497.
https://doi.org/10.1182/blood.V120.21.3497.3497
Published: 2012
Journal Articles

Regulation of Myelopoiesis by Differentiation Stage-Specific Activities of HOXA9 and HOXA10

Elizabeth A. Eklund, MD
Journal: Blood
Blood (2012) 120 (21): SCI-29.
https://doi.org/10.1182/blood.V120.21.SCI-29.SCI-29
Published: 2012
Journal Articles

Fap1 Controls Beta-Catenin Activity in a Gsk3-Beta Dependent Manner in Chronic Myeloid Leukemia.

Weiqi Huang, PhD, Ling Bei, MD, Elizabeth A. Eklund, MD
Journal: Blood
Blood (2012) 120 (21): 2404.
https://doi.org/10.1182/blood.V120.21.2404.2404
Published: 2012
Journal Articles

Icsbp/Irf8 Cooperates with Tel to Regulate Fas Induced Apoptosis in Myeloid Leukemia.

Weiqi Huang, PhD, Elizabeth A. Eklund, MD
Journal: Blood
Blood (2011) 118 (21): 395.
https://doi.org/10.1182/blood.V118.21.395.395
Published: 2011
Journal Articles

HoxA10 Regulates Myeloid Progenitor Proliferation by Activating Transcription of the Gene Encoding Transforming Growth Factor Beta 2.

Chirag Shah, PhD, Hao Wang, PhD, Elizabeth A. Eklund, MD
Journal: Blood
Blood (2010) 116 (21): 1572.
https://doi.org/10.1182/blood.V116.21.1572.1572
Published: 2010
Journal Articles

Geminin Regulates Hematopoietic Stem Cell Proliferation and Differentiation.

Kathryn M. Shinnick, Kelly A. Barry, Elizabeth A. Eklund, MD, Thomas J. McGarry, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1478.
https://doi.org/10.1182/blood.V114.22.1478.1478
Published: 2009
Journal Articles

Bcr/Abl Increases Bcatenin Protein and Activity in An ICSBP-Dependent Manner in Myeloid Cells.

Weiqi Huang, Research, Assistant, Professor, Elizabeth Horvath, MS, Elizabeth A. Eklund, MD
Journal: Blood
Blood (2009) 114 (22): 2958.
https://doi.org/10.1182/blood.V114.22.2958.2958
Published: 2009
Journal Articles

The Role of Hox Proteins and Interferon Regulatory Factors in Myeloid Differentiation.

Elizabeth A. Eklund, MD
Journal: Blood
Blood (2008) 112 (11): sci-34.
https://doi.org/10.1182/blood.V112.11.sci-34.sci-34
Published: 2008
Journal Articles

Constitutive Activation of SHP2 Protein Tyrosine Phosphatase Cooperates with HoxA10 Overexpression for Progression to Acute Myeloid Leukemia in a Murine Model

Hao Wang, MD, Stephan Lindsey, PhD, Iwona Konieczna, Elizabeth Horvath, MS, Ling Bei, MD, Weiqi Huang, MD, PhD, Elizabeth A. Eklund, MD
Journal: Blood
Blood (2008) 112 (11): 752.
https://doi.org/10.1182/blood.V112.11.752.752
Published: 2008
Journal Articles

Leukemia Associated Mutants of SHP2 Protein Tyrosine Phosphatase Inhibit Nf1-Expression by Decreasing ICSBP and IRF2 Phosphorylation.

Weiqi Huang, PhD, Elizabeth Horvath, Elizabeth A. Eklund, MD
Journal: Blood
Blood (2006) 108 (11): 1165.
https://doi.org/10.1182/blood.V108.11.1165.1165
Published: 2006
Journal Articles

Leukemia Associated Mutants of SHP2 Protein Tyrosine Phosphatase Prevent HoxA10 Tyrosine Phosphorylation in Differentiating Myeloid Cells, Thereby Blocking Transcription of the Gene Encoding Gp91phox.

Stephan Lindsey, Hao Wang, PhD, Elizabeth A. Eklund, MD
Journal: Blood
Blood (2006) 108 (11): 504.
https://doi.org/10.1182/blood.V108.11.504.504
Published: 2006
Journal Articles

HoxA10 Represses Transcription of Multiple Genes Encoding Respiratory Burst Oxidase Proteins in Undifferentiated Myeloid Cells.

Stephan Lindsey, YuFeng Lu, Elizabeth A. Eklund, MD
Journal: Blood
Blood (2005) 106 (11): 632.
https://doi.org/10.1182/blood.V106.11.632.632
Published: 2005