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Jairo A. Matthews
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Journal Articles

Gene Expression Analysis of CML Patients across the Age Spectrum

Minyoung Youn, Stephanie M. Smith, Alex Gia Lee, Hee-Don Chae, Elizabeth Spiteri, Jason Erdmann, Ilana Galperin, Lara C. Murphy, Michele Donato, Parveen Abidi, Henrique Bittencourt, Norman J. Lacayo, Gary Dahl, Catherine Aftandilian, Kara L. Davis, Jairo A. Matthews, Steven M. Kornblau, Min Huang, Nathan Sumarsono, Michele Redell, Cecilia H. Fu, I-Ming L Chen, Todd A. Alonzo, Elizabeth A. Eklund, Jason Gotlib, Purvesh Khatri, Alejandro Sweet-Cordero, Nobuko Hijiya, Kathleen M. Sakamoto
Journal: Blood
Blood (2021) 138 (Supplement 1): 1473.
https://doi.org/10.1182/blood-2021-148701
Published: 2021
Journal Articles

Quizartinib (Quiz) with Decitabine (DAC) and Venetoclax (VEN) Is Highly Active in Patients (pts) with FLT3-ITD Mutated Acute Myeloid Leukemia (AML) - RAS/MAPK Mutations Continue to Drive Primary and Secondary Resistance

Musa Yilmaz, Muharrem Muftuoglu, Hagop Kantarjian, Courtney D. DiNardo, Tapan M. Kadia, Marina Konopleva, Gautam Borthakur, Naveen Pemmaraju, Nicholas J. Short, Yesid Alvarado, Abhishek Maiti, Lucia Masarova, Guillermo Montalban-Bravo, Carissa Jurisprudencia, Allison M. Pike, Sanam Loghavi, Keyur Patel, Guilin Tang, Jairo A. Matthews, Steven M. Kornblau, Elias J. Jabbour, Guillermo Garcia-Manero, Vivian Ruvolo, Farhad Ravandi, Michael Andreeff, Naval Daver
Journal: Blood
Blood (2021) 138 (Supplement 1): 370.
https://doi.org/10.1182/blood-2021-153426
Published: 2021
Journal Articles

"Triple" Combination of Targeting Methyltransferase, BCL-2 and PD-1 Facilitates Therapeutic Responses in Acute Myeloid Leukemia (AML)

Zhihong Zeng, MD, Shelley Herbrich, PhD, Tianyu Cai, PhD, Antonio Cavazos, MSc, Taylor Manzella, Helen Ma, MS, Vinitha Mary Kuruvilla, MSc, Kala Hayes, Jairo A. Matthews, Courtney D. DiNardo, MD MSCE, Naval Daver, MD, Marina Konopleva, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 9–10.
https://doi.org/10.1182/blood-2020-142031
Published: 2020
Journal Articles

Comparison of the Transcriptomic Signatures in Pediatric and Adult CML

Minyoung Youn, PhD, Hee-Don Chae, PhD, Stephanie M. Smith, MD, Alex Gia Lee, PhD, Lara C. Murphy, MD, Michele Donato, PhD, Alejandro Sweet-Cordero, Parveen Abidi, PhD, Henrique Bittencourt, MD PhD, Norman J. Lacayo, MD, Gary Dahl, Catherine Aftandilian, MD, Kara L Davis, DO, Jairo A. Matthews, Steven M. Kornblau, MD, Min Huang, PhD, Nathan Sumarsono, BS, Michele Redell, MD, Cecilia H. Fu, MD, I-Ming L Chen, Todd A. Alonzo, PhD, Elizabeth A. Eklund, MD, Jason Gotlib, MD MS, Purvesh Khatri, PhD, Nobuko Hijiya, MD, Kathleen M. Sakamoto, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39–40.
https://doi.org/10.1182/blood-2020-142270
Published: 2020
Journal Articles

Single-Cell Characterization of Acute Myeloid Leukemia (AML) and Its Microenvironment Identifies Signatures of Resistance to PD-1 Blockade Based Therapy

Hussein A Abbas, MDPhD, Dapeng Hao, Katarzyna Tomczak, PhD, Praveen Barrodia, Jin S. Im, Patrick K Reville, MD, Zoe Alaniz, Wei Wang, MD PhD, Ruiping Wang, PhD, Feng Wang, PhD, Koichi Takahashi, MD PhD, Jing Ning, PhD, Maomao Ding, Jairo A. Matthews, Latasha Little, BS, Jianhua Zhang, PhD, Sreyashi Basu, PhD, Courtney D. DiNardo, MD MSCE, Tapan M. Kadia, MD, Farhad Ravandi, MBBS, Gautam Borthakur, MD, Marina Konopleva, MD PhD, Guillermo Garcia-Manero, MD, Michael R Green, PhD, Gheath Alatrash, Padmanee Sharma, James P Allison, PhD, Steven M. Kornblau, MD, Kunal Rai, Linghua Wang, PhD, P Andrew Futreal, PhD, Naval Daver, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 29–31.
https://doi.org/10.1182/blood-2020-137335
Published: 2020
Journal Articles

Azacitidine (AZA) with Nivolumab (Nivo), and AZA with Nivo + Ipilimumab (Ipi) in Relapsed/Refractory (R/R) Acute Myeloid Leukemia: Clinical and Immune Biomarkers of Response

Naval Daver, MD, Sreyashi Basu, PhD, Guillermo Garcia-Manero, MD, Hussein A Abbas, MDPhD, Marina Konopleva, MD PhD, Tapan M. Kadia, MD, Courtney D. DiNardo, MD MSCE, Gautam Borthakur, MD, Ahmad S. Alotaibi, MD, Naveen Pemmaraju, MD, Elias Jabbour, MD, Sherry A. Pierce, BSN, BA, Mark Brandt, BS, Koichi Takahashi, MD PhD, Jing Ning, Steven M. Kornblau, MD, Koji Sasaki, MD, Musa Yilmaz, MD, Ghayas C. Issa, MD, Nicholas J. Short, MD, Jairo A. Matthews, Wilmer Flores, Michael Andreeff, MD PhD, Jorge E. Cortes, MD, Farhad Ravandi, MBBS, James P Allison, PhD, Hagop M. Kantarjian, MD, Padmanee Sharma
Journal: Blood
Blood (2020) 136 (Supplement 1): 43–45.
https://doi.org/10.1182/blood-2020-142824
Published: 2020
Journal Articles

Ultrasensitive Next-Generation Sequencing-Based Measurable Residual Disease Assessment in Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia after Frontline Therapy: Correlation with Flow Cytometry and Impact on Clinical Outcomes

Nicholas J. Short, MD, Hagop M. Kantarjian, MD, Keyur Patel, MD PhD, Steven M. Kornblau, MD, Jeffrey L. Jorgensen, MD PhD, Sa A Wang, MD, Marina Konopleva, MD PhD, Nitin Jain, MD, Partow Kebriaei, MD, Musa Yilmaz, MD, Ghayas C. Issa, MD, Jairo A. Matthews, Munazza Noor, Rebecca Garris, MSc, Farhad Ravandi, MBBS, Elias Jabbour, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 26–28.
https://doi.org/10.1182/blood-2020-141971
Published: 2020
Journal Articles

Inhibition of Interleukin-6 Signaling with CNTO 328 Sensitizes Plasma Cell Dyscrasias to the Effects of Melphalan in Association with Suppression of Signaling through Protein Kinase B/Akt.

Sally A. Hunsucker, Ph.D., Valeria Magarotto, M.D., Jairo A. Matthews, B.A., Michael Wang, M.D., Veerabhadran Baladandayuthapani, Ph.D., Peter M. Voorhees, M.D., Hong Xie, M.D., Mark Cornfeld, M.D., M.P.H., Jeffrey A. Nemeth, M.D., Ph.D., Robert Z. Orlowski, M.D., Ph.D.
Journal: Blood
Blood (2009) 114 (22): 1836.
https://doi.org/10.1182/blood.V114.22.1836.1836
Published: 2009
Journal Articles

Activation of the Wnt/β-Catenin Pathway Mediates Lenalidomide Resistance in Multiple Myeloma.

Chad C. Bjorklund, Ph.D., Deborah J. Kuhn, Ph.D., B.Sc., Jairo A. Matthews, B.A., Michael Wang, M.D., Veerabhadran Baladandayuthapani, Ph.D., Robert Z. Orlowski, M.D., Ph.D.
Journal: Blood
Blood (2009) 114 (22): 113.
https://doi.org/10.1182/blood.V114.22.113.113
Published: 2009
Journal Articles

Myeloma and the Microenvironment: Macrophages Are a Protector of Myeloma Cells Apoptosis Induced by Chemotherapy Drugs.

Jing Yang, PhD, Yuhuan Zheng, Zhen Cai, Jianfei Qian, PhD, Sungyoul Hong, Haiyan Li, Jairo A. Matthews, BA, Michael Wang, MD, Qing Yi, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 4804.
https://doi.org/10.1182/blood.V114.22.4804.4804
Published: 2009
Journal Articles

Constitutive Activation of p38 MAPK in Myeloma Cells Contributes to Myeloma-Induced Osteolytic Bone Lesions.

Jing Yang, PhD, Yabing Cao, Yuhuan Zheng, Sungyoul Hong, Haiyan Li, Jianfei Qian, PhD, Jairo A. Matthews, BA, Michael Wang, MD, Larry W. Kwak, Qing Yi, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 740.
https://doi.org/10.1182/blood.V114.22.740.740
Published: 2009
Journal Articles

Bortezomib Resistance Is Mediated by Increased Signaling through the Insulin-Like Growth Factor-1/Akt Axis.

Deborah J. Kuhn, Ph.D., Chad C. Bjorklund, Ph.D., Valeria Magarotto, M.D., Jairo A. Matthews, B.A., Michael Wang, M.D., Veerabhadran Baladandayuthapani, Ph.D., Robert Z. Orlowski, M.D., Ph.D.
Journal: Blood
Blood (2009) 114 (22): 2739.
https://doi.org/10.1182/blood.V114.22.2739.2739
Published: 2009