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Elias J. Jabbour
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Journal Articles

Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL

Yaqi Zhao, Nicholas J. Short, Hagop M. Kantarjian, Ti-Cheng Chang, Pankaj S. Ghate, Chunxu Qu, Walid Macaron, Nitin Jain, Beenu Thakral, Aaron H. Phillips, Joseph Khoury, Guillermo Garcia-Manero, Wenchao Zhang, Yiping Fan, Hui Yang, Rebecca S. Garris, Lewis F. Nasr, Richard W. Kriwacki, Kathryn G. Roberts, Marina Konopleva, Elias J. Jabbour, Charles G. Mullighan
Journal: Blood
Blood (2024) 144 (1): 61–73.
https://doi.org/10.1182/blood.2024023930
Published: 2024
Includes: Supplemental data
Journal Articles

International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data

Daniel A. Arber, Attilio Orazi, Robert P. Hasserjian, Michael J. Borowitz, Katherine R. Calvo, Hans-Michael Kvasnicka, Sa A. Wang, Adam Bagg, Tiziano Barbui, Susan Branford, Carlos E. Bueso-Ramos, Jorge E. Cortes, Paola Dal Cin, Courtney D. DiNardo, Hervé Dombret, Eric J. Duncavage, Benjamin L. Ebert, Elihu H. Estey, Fabio Facchetti, Kathryn Foucar, Naseema Gangat, Umberto Gianelli, Lucy A. Godley, Nicola Gökbuget, Jason Gotlib, Eva Hellström-Lindberg, Gabriela S. Hobbs, Ronald Hoffman, Elias J. Jabbour, Jean-Jacques Kiladjian, Richard A. Larson, Michelle M. Le Beau, Mignon L.-C. Loh, Bob Löwenberg, Elizabeth Macintyre, Luca Malcovati, Charles G. Mullighan, Charlotte Niemeyer, Olatoyosi M. Odenike, Seishi Ogawa, Alberto Orfao, Elli Papaemmanuil, Francesco Passamonti, Kimmo Porkka, Ching-Hon Pui, Jerald P. Radich, Andreas Reiter, Maria Rozman, Martina Rudelius, Michael R. Savona, Charles A. Schiffer, Annette Schmitt-Graeff, Akiko Shimamura, Jorge Sierra, Wendy A. Stock, Richard M. Stone, Martin S. Tallman, Jürgen Thiele, Hwei-Fang Tien, Alexandar Tzankov, Alessandro M. Vannucchi, Paresh Vyas, Andrew H. Wei, Olga K. Weinberg, Agnieszka Wierzbowska, Mario Cazzola, Hartmut Döhner, Ayalew Tefferi
Journal: Blood
Blood (2022) 140 (11): 1200–1228.
https://doi.org/10.1182/blood.2022015850
Published: 2022
Includes: Supplemental data
Journal Articles

TP53 copy number and protein expression inform mutation status across risk categories in acute myeloid leukemia

Mehrnoosh Tashakori, Tapan Kadia, Sanam Loghavi, Naval Daver, Rashmi Kanagal-Shamanna, Sherry Pierce, Dawen Sui, Peng Wei, Farnoosh Khodakarami, Zhenya Tang, Mark Routbort, Carol A. Bivins, Elias J. Jabbour, L. Jeffrey Medeiros, Kapil Bhalla, Hagop M. Kantarjian, Farhad Ravandi, Joseph D. Khoury
Journal: Blood
Blood (2022) 140 (1): 58–72.
https://doi.org/10.1182/blood.2021013983
Published: 2022
Includes: Supplemental data
Journal Articles

Enhancer retargeting of CDX2 and UBTF::ATXN7L3 define a subtype of high-risk B-progenitor acute lymphoblastic leukemia

Shunsuke Kimura, Lindsey Montefiori, Ilaria Iacobucci, Yaqi Zhao, Qingsong Gao, Elisabeth M. Paietta, Claudia Haferlach, A. Douglas Laird, Paul E. Mead, Zhaohui Gu, Wendy Stock, Mark Litzow, Jacob M. Rowe, Selina M. Luger, Stephen P. Hunger, Georgina L. Ryland, Breon Schmidt, Paul G. Ekert, Alicia Oshlack, Sean M. Grimmond, Jacqueline Rehn, James Breen, David Yeung, Deborah L. White, Ibrahim Aldoss, Elias J. Jabbour, Ching-Hon Pui, Manja Meggendorfer, Wencke Walter, Wolfgang Kern, Torsten Haferlach, Samuel Brady, Jinghui Zhang, Kathryn G. Roberts, Piers Blombery, Charles G. Mullighan
Journal: Blood
Blood (2022) 139 (24): 3519–3531.
https://doi.org/10.1182/blood.2022015444
Published: 2022
Includes: Supplemental data
Journal Articles

A Phase II Study of Mini-Hyper-CVD Plus Venetoclax in Patients with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia

Sangeetha Venugopal, Hagop Kantarjian, Nicholas J. Short, Philip A. Thompson, Naveen Pemmaraju, Nitin Jain, William G. Wierda, Gautam Borthakur, Guillermo Montalban-Bravo, Farhad Ravandi, Guillermo Garcia-Manero, Tapan M. Kadia, Maro Ohanian, Kelly S. Chien, Jennifer Thankachan, Benjamin Nwakanme, Rebecca Garris, Elias J. Jabbour
Journal: Blood
Blood (2021) 138 (Supplement 1): 1239.
https://doi.org/10.1182/blood-2021-153826
Published: 2021
Journal Articles

A Phase 1 Trial of Adct-602, a CD22 Targeting Antibody Drug Conjugate Bound to PBD Toxin in Adult Patients with Relapsed or Refractory CD22+ B-Cell Acute Lymphoblastic Leukemia

Nitin Jain, Elias J. Jabbour, Marina Konopleva, Naveen Pemmaraju, Philip A. Thompson, Nicholas J. Short, Tapan M. Kadia, Gautam Borthakur, Naval Daver, Courtney D. DiNardo, Ibrahim Aldoss, Robin Cook, Farhad Ravandi, Hagop Kantarjian
Journal: Blood
Blood (2021) 138 (Supplement 1): 1237.
https://doi.org/10.1182/blood-2021-153141
Published: 2021
Journal Articles

Updated Results from a Phase II Study of Hyper-CVAD with Sequential Blinatumomab in Adults with Newly Diagnosed Philadelphia Chromosome-Negative B-Cell Acute Lymphoblastic Leukemia

Nicholas J. Short, Hagop Kantarjian, Farhad Ravandi, Xuelin Huang, Philip A. Thompson, Alessandra Ferrajoli, Tapan M. Kadia, Nitin Jain, Yesid Alvarado, Musa Yilmaz, Joseph D. Khoury, Jeffrey L. Jorgensen, Sa A Wang, Steven M. Kornblau, Marina Konopleva, Guillermo Garcia-Manero, Rebecca Garris, Heather M Schroeder, Anna Milton, Juan Rivera, Glenda Banks, Elias J. Jabbour
Journal: Blood
Blood (2021) 138 (Supplement 1): 1233.
https://doi.org/10.1182/blood-2021-154022
Published: 2021
Journal Articles

Ten-Day Decitabine with Venetoclax (DEC10-VEN) in Acute Myeloid Leukemia and Myelodysplastic Syndrome: Updated Results of a Phase II Trial

Abhishek Maiti, Courtney D. DiNardo, Caitlin R. Rausch, Naveen Pemmaraju, Guillermo Garcia-Manero, Maro Ohanian, Naval Daver, Ghayas C. Issa, Gautam Borthakur, Farhad Ravandi, Yesid Alvarado, Tapan M. Kadia, Nicholas J. Short, Elias J. Jabbour, Guillermo Montalban-Bravo, Nitin Jain, Steven M. Kornblau, Lucia Masarova, William G. Wierda, Koji Sasaki, Koichi Takahashi, Musa Yilmaz, Jan A. Burger, Zeev E. Estrov, Srdan Verstovsek, Michael Andreeff, Prithviraj Bose, Alessandra Ferrajoli, Philip A. Thompson, Kathryn Montalbano, Kenneth Vaughan, Carol A. Bivins, Sherry A. Pierce, Wei Qiao, Jing Ning, John Welch, Hagop Kantarjian, Marina Konopleva
Journal: Blood
Blood (2021) 138 (Supplement 1): 1270.
https://doi.org/10.1182/blood-2021-153530
Published: 2021
Journal Articles

Evolution of Genomic Landscape in Acute Myeloid Leukemia after Decitabine and Venetoclax

Abhishek Maiti, Courtney D. DiNardo, Naval Daver, Tapan M. Kadia, Gautam Borthakur, Nicholas J. Short, Naveen Pemmaraju, Maro Ohanian, Yesid Alvarado, Koichi Takahashi, Sherry A. Pierce, Keyur P. Patel, Elias J. Jabbour, Guillermo Garcia-Manero, Farhad Ravandi, Hagop Kantarjian, Marina Konopleva
Journal: Blood
Blood (2021) 138 (Supplement 1): 1304.
https://doi.org/10.1182/blood-2021-151756
Published: 2021
Journal Articles

Preliminary Results from the Flu/Cy/Alemtuzumab Arm of the Phase I BALLI-01 Trial of UCART22, an Anti-CD22 Allogeneic CAR-T Cell Product, in Adult Patients with Relapsed or Refractory (R/R) CD22+ B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Nitin Jain, Gail J. Roboz, Marina Konopleva, Hongtao Liu, Gary J. Schiller, Elias J. Jabbour, Deborah Whitfield, Asifa Haider, Oleg Zernovak, Mark G. Frattini, Carrie Brownstein, Richard A. Larson
Journal: Blood
Blood (2021) 138 (Supplement 1): 1746.
https://doi.org/10.1182/blood-2021-150779
Published: 2021
Journal Articles

A Phase II Study of CPX-351 Plus Venetoclax in Patients with Relapsed/Refractory (R/R) or Newly Diagnosed Acute Myeloid Leukemia (AML)

Kunhwa Kim, Hagop Kantarjian, Gautam Borthakur, Koichi Takahashi, Nicholas J. Short, Courtney D. DiNardo, Elias J. Jabbour, Kelly S. Chien, Naval Daver, Naveen Pemmaraju, Nitin Jain, Lade Adewale, Guillermo Montalban-Bravo, William G. Wierda, Srdan Verstovsek, Marina Konopleva, Farhad Ravandi, Tapan M. Kadia
Journal: Blood
Blood (2021) 138 (Supplement 1): 1275.
https://doi.org/10.1182/blood-2021-154148
Published: 2021
Journal Articles

Adoptive Therapy with Allogeneic Cord Blood T Regulatory Cells Improves Transfusion Requirement in Bone Marrow Failure Syndromes

Tapan M. Kadia, Naveen Pemmaraju, Musa Yilmaz, Naval Daver, Li Li, Mi-Ae Lyu, Meixian Huang, Ke Zeng, Robin Cook, Simrit Parmar, Siddhartha Mukherjee, Tara Sadeghi, Courtney D. DiNardo, Ghayas C. Issa, Elias J. Jabbour, Gautam Borthakur, Nitin Jain, Srdan Verstovsek
Journal: Blood
Blood (2021) 138 (Supplement 1): 3875.
https://doi.org/10.1182/blood-2021-153864
Published: 2021
Journal Articles

A Phase II Study of Blinatumomab for the Treatment of Measurable Residual Disease-Positive B-Cell Acute Lymphoblastic Leukemia

Fadi Haddad, Hagop Kantarjian, Nicholas J. Short, Marina Konopleva, Nitin Jain, Farhad Ravandi, Naval Daver, Yesid Alvarado, Koichi Takahashi, Guillermo Garcia-Manero, Michelle Velasquez, Rebecca Garris, Elias J. Jabbour
Journal: Blood
Blood (2021) 138 (Supplement 1): 4398.
https://doi.org/10.1182/blood-2021-149261
Published: 2021
Journal Articles

Heterogeneity of Minimal/Measurable Residual Disease (MRD) Practices in Adult B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) in the United States

Juliana E. Hidalgo-Lopez, Gail J. Roboz, Brent Wood, Michael Borowitz, Elias J. Jabbour, Kelly Velasco, Ehab Elkhouly, Babatunde Adedokun, Faraz Zaman, Karim Iskander, Aaron C. Logan
Journal: Blood
Blood (2021) 138 (Supplement 1): 4478.
https://doi.org/10.1182/blood-2021-144353
Published: 2021
Journal Articles

Phase II Study of Lower-Intensity Frontline Therapy for Newly Diagnosed Patients with AML Who Are Unfit or Otherwise Not Eligible for Frontline Clinical Trials

Sangeetha Venugopal, Elias J. Jabbour, Naveen Pemmaraju, Guillermo Montalban-Bravo, Kelly S. Chien, Naval Daver, Nitin Jain, Jan A. Burger, Yesid Alvarado, Abhishek Maiti, Courtney D. DiNardo, Gautam Borthakur, Rashmi Malla, Guillermo Garcia-Manero, Farhad Ravandi, Hagop Kantarjian, Tapan M. Kadia
Journal: Blood
Blood (2021) 138 (Supplement 1): 4420.
https://doi.org/10.1182/blood-2021-153044
Published: 2021
Journal Articles

A Phase II Study of Azacitidine, Venetoclax and Trametinib in Relapsed/Refractory AML Harboring a Ras Pathway-Activating Mutation

Sai Prasad Desikan, Farhad Ravandi, Naveen Pemmaraju, Marina Konopleva, Sanam Loghavi, Gautam Borthakur, Elias J. Jabbour, Naval Daver, Nitin Jain, Kelly S. Chien, Abhishek Maiti, Guillermo Montalban-Bravo, Tapan M. Kadia, Monica Kwari, Hagop Kantarjian, Nicholas J. Short
Journal: Blood
Blood (2021) 138 (Supplement 1): 4436.
https://doi.org/10.1182/blood-2021-151707
Published: 2021
Journal Articles

Clinical Outcomes of Patients with Newly Diagnosed Myelodysplastic Syndrome with MLL Aberrations

Maria Siddiqui, Ghayas C. Issa, Koji Sasaki, Guillermo Montalban-Bravo, Kelly S. Chien, Elias J. Jabbour, Carlos E. Bueso-Ramos, Rashmi Kanagal-Shamanna, Hagop Kantarjian, Guillermo Garcia-Manero
Journal: Blood
Blood (2021) 138 (Supplement 1): 4673.
https://doi.org/10.1182/blood-2021-151670
Published: 2021
Journal Articles

Trial in Progress: Phase 1b Bridging Study of the Pharmacokinetics (PK), Safety, and Efficacy of Orally Administered Olverembatinib (HQP1351) in Patients with Refractory Chronic Myeloid Leukemia (CML) and Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph⁺ ALL)

Elias J. Jabbour, Hagop Kantarjian, Ghayas C. Issa, Joseph Thaddeus Beck, Rebecca B. Klisovic, Sudipto Mukherjee, Vivian G. Oehler, Zi Chen, Ming Lu, Tommy Fu, Lixin Jiang, Yifan Zhai, Dajun Yang
Journal: Blood
Blood (2021) 138 (Supplement 1): 2551.
https://doi.org/10.1182/blood-2021-152693
Published: 2021
Journal Articles

Dose Modification Dynamics of Ponatinib in Patients with Chronic-Phase Chronic Myeloid Leukemia (CP-CML) from the PACE and Optic Trials

Elias J. Jabbour, Michael W. Deininger, Elisabetta Abruzzese, Jane F Apperley, Jorge E. Cortes, Charles Chuah, Daniel J. DeAngelo, John F. DiPersio, Andreas Hochhaus, Jeffrey H. Lipton, Franck E. Nicolini, Javier Pinilla Ibarz, Delphine Rea, Gianantonio Rosti, Philippe Rousselot, Michael J. Mauro, Neil P Shah, Moshe Talpaz, Alexander Vorog, Vickie Lu, Hagop Kantarjian
Journal: Blood
Blood (2021) 138 (Supplement 1): 2550.
https://doi.org/10.1182/blood-2021-146175
Published: 2021
Journal Articles

The Prognostic Implication of Adult Comorbidity Evaluation 27 Score in CML Patients on Tyrosine-Kinase Inhibitors

Kunhwa Kim, Hagop Kantarjian, Elias J. Jabbour, Ghayas C. Issa, Farhad Ravandi, Courtney D. DiNardo, Marina Konopleva, Nitin Jain, Naveen Pemmaraju, Gautam Borthakur, Tapan M. Kadia, Guillermo Garcia-Manero, Kiyomi Morita, Sherry A. Pierce, Jorge E. Cortes, Koji Sasaki
Journal: Blood
Blood (2021) 138 (Supplement 1): 2554.
https://doi.org/10.1182/blood-2021-154497
Published: 2021