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Journal Articles

Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL

Yaqi Zhao, Nicholas J. Short, Hagop M. Kantarjian, Ti-Cheng Chang, Pankaj S. Ghate, Chunxu Qu, Walid Macaron, Nitin Jain, Beenu Thakral, Aaron H. Phillips, Joseph Khoury, Guillermo Garcia-Manero, Wenchao Zhang, Yiping Fan, Hui Yang, Rebecca S. Garris, Lewis F. Nasr, Richard W. Kriwacki, Kathryn G. Roberts, Marina Konopleva, Elias J. Jabbour, Charles G. Mullighan
Journal: Blood
Blood (2024) 144 (1): 61–73.
https://doi.org/10.1182/blood.2024023930
Published: 2024
Includes: Supplemental data
Journal Articles

Assessment of Outcomes of Consolidation Therapy By Number of Cycles of Blinatumomab Received in Newly Diagnosed Measurable Residual Disease Negative Patients with B-Lineage Acute Lymphoblastic Leukemia: In the ECOG-ACRIN E1910 Randomized Phase III National Clinical Trials Network Trial

Selina M Luger, Zhuoxin Sun, Ryan J Mattison, Elisabeth Paietta, Kathryn G. Roberts, Yanming Zhang, Janis Racevckis, Hillard M. Lazarus, Jacob M. Rowe, Daniel A. Arber, Matthew J. Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent L. Wood, Yaqi Zhao, Gang Wu, Ti-Cheng Chang, Wenchao Zhang, Keith W Pratz, Shira N. Dinner, Noelle V. Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L Uy, Deepa Jeyakumar, Tara L Lin, Cheryl L. Willman, Daniel J. DeAngelo, Elad Sharon, Richard F. Little, Harry P. Erba, Richard M Stone, Charles G. Mullighan, Mark R. Litzow, Martin S. Tallman
Journal: Blood
Blood (2023) 142 (Supplement 1): 2877.
https://doi.org/10.1182/blood-2023-189648
Published: 2023
Journal Articles

Enhancer retargeting of CDX2 and UBTF::ATXN7L3 define a subtype of high-risk B-progenitor acute lymphoblastic leukemia

Shunsuke Kimura, Lindsey Montefiori, Ilaria Iacobucci, Yaqi Zhao, Qingsong Gao, Elisabeth M. Paietta, Claudia Haferlach, A. Douglas Laird, Paul E. Mead, Zhaohui Gu, Wendy Stock, Mark Litzow, Jacob M. Rowe, Selina M. Luger, Stephen P. Hunger, Georgina L. Ryland, Breon Schmidt, Paul G. Ekert, Alicia Oshlack, Sean M. Grimmond, Jacqueline Rehn, James Breen, David Yeung, Deborah L. White, Ibrahim Aldoss, Elias J. Jabbour, Ching-Hon Pui, Manja Meggendorfer, Wencke Walter, Wolfgang Kern, Torsten Haferlach, Samuel Brady, Jinghui Zhang, Kathryn G. Roberts, Piers Blombery, Charles G. Mullighan
Journal: Blood
Blood (2022) 139 (24): 3519–3531.
https://doi.org/10.1182/blood.2022015444
Published: 2022
Includes: Supplemental data
Journal Articles

Tumor-intrinsic and -extrinsic determinants of response to blinatumomab in adults with B-ALL

Clinical Trials & Observations
Yaqi Zhao, Ibrahim Aldoss, Chunxu Qu, Jeremy Chase Crawford, Zhaohui Gu, Emma K. Allen, Anthony E. Zamora, Thomas B. Alexander, Jeremy Wang, Hiroaki Goto, Toshihiko Imamura, Koshi Akahane, Guido Marcucci, Anthony S. Stein, Ravi Bhatia, Paul G. Thomas, Stephen J. Forman, Charles G. Mullighan, Kathryn G. Roberts
Journal: Blood
Blood (2021) 137 (4): 471–484.
https://doi.org/10.1182/blood.2020006287
Published: 2021
Includes: Supplemental data
Journal Articles

Inotuzumab Ozogamicin (Ino) May Overcome the Impact of Philadelphia Chromosome (Ph)-like Phenotype in Adult Patients (pts) with Relapsed/Refractory (R/R) Acute Lymphoblastic Leukemia (ALL)

Elias Jabbour, MD, Kathryn G. Roberts, PhD, Koji Sasaki, MD, Yaqi Zhao, MSc, Chunxu Qu, PhD, Zhaohui Gu, PhD, Nitin Jain, MD, Keyur P. Patel, MBBS, PhD, Farhad Ravandi, MD, Nicholas J. Short, MD, Guillermo Garcia-Manero, MD, Rebecca Garris, MSc, Steven Kornblau, Marina Y Konopleva, MD PhD, Charles G. Mullighan, MBBS, MD, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1641.
https://doi.org/10.1182/blood-2019-126940
Published: 2019
Journal Articles

Genomic Determinants of Response to Blinatumomab in Relapsed/Refractory (R/R) B-Cell Precursor Acute Lymphoblastic Leukemia in Adults

Yaqi Zhao, MSc, Ibrahim Aldoss, MD, Chunxu Qu, PhD, Guido Marcucci, Anthony S. Stein, MD, Ravi Bhatia, MD, Charles G. Mullighan, MBBS, MD, Stephen J Forman, Kathryn G. Roberts, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1552.
https://doi.org/10.1182/blood-2018-99-113604
Published: 2018
Journal Articles

Genomic and outcome analyses of Ph-like ALL in NCI standard-risk patients: a report from the Children’s Oncology Group

Clinical Trials & Observations
Kathryn G. Roberts, Shalini C. Reshmi, Richard C. Harvey, I-Ming Chen, Kinnari Patel, Eileen Stonerock, Heather Jenkins, Yunfeng Dai, Marc Valentine, Zhaohui Gu, Yaqi Zhao, Jinghui Zhang, Debbie Payne-Turner, Meenakshi Devidas, Nyla A. Heerema, Andrew J. Carroll, Elizabeth A. Raetz, Michael J. Borowitz, Brent L. Wood, Leonard A. Mattano, Jr, Kelly W. Maloney, William L. Carroll, Mignon L. Loh, Cheryl L. Willman, Julie M. Gastier-Foster, Charles G. Mullighan, Stephen P. Hunger
Journal: Blood
Blood (2018) 132 (8): 815–824.
https://doi.org/10.1182/blood-2018-04-841676
Published: 2018
Includes: Supplemental data
Journal Articles

ETV6-NTRK3 induces aggressive acute lymphoblastic leukemia highly sensitive to selective TRK inhibition

Kathryn G. Roberts, Laura J. Janke, Yaqi Zhao, Aman Seth, Jing Ma, David Finkelstein, Steve Smith, Kevin Ebata, Brian B. Tuch, Stephen P. Hunger, Charles G. Mullighan
Journal: Blood
Blood (2018) 132 (8): 861–865.
https://doi.org/10.1182/blood-2018-05-849554
Published: 2018
Includes: Supplemental data