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Journal Articles

Degradation of Janus kinases in CRLF2 -rearranged acute lymphoblastic leukemia

Yunchao Chang, Jaeki Min, Jamie A. Jarusiewicz, Marisa Actis, Shanshan Yu-Chen Bradford, Anand Mayasundari, Lei Yang, Divyabharathi Chepyala, Lisa J. Alcock, Kathryn G. Roberts, Stanley Nithianantham, Dylan Maxwell, Lauren Rowland, Randolph Larsen, Aman Seth, Hiroaki Goto, Toshihiko Imamura, Koshi Akahane, Baranda S. Hansen, Shondra M. Pruett-Miller, Elisabeth M. Paietta, Mark R. Litzow, Chunxu Qu, Jun J. Yang, Marcus Fischer, Zoran Rankovic, Charles G. Mullighan
Journal: Blood
Blood (2021) 138 (23): 2313–2326.
https://doi.org/10.1182/blood.2020006846
Published: 2021
Includes: Supplemental data
Journal Articles

Loss of PTEN in Pediatric AML Confers Sensitivity to PARP Inhibition

Jennifer Lauren Kamens, Anitria Cotton, Jeannie W Lam, Jinjun Dang, Aman Seth, Baranda S Hansen, Shondra M. Pruett-Miller, Anang Shelat, Tanja Andrea Gruber
Journal: Blood
Blood (2021) 138 (Supplement 1): 3446.
https://doi.org/10.1182/blood-2021-146694
Published: 2021
Journal Articles

Modeling and targeting of erythroleukemia by hematopoietic genome editing

Ilaria Iacobucci, Chunxu Qu, Elena Varotto, Laura J. Janke, Xu Yang, Aman Seth, Anang Shelat, Jake D. Friske, Reiji Fukano, Jiyang Yu, Burgess B. Freeman, III, James A. Kennedy, Adam S. Sperling, Rena Zheng, Yingzhe Wang, Harini Jogiraju, Kirsten M. Dickerson, Debbie Payne-Turner, Sarah M. Morris, Emily S. Hollis, Nina Ghosn, Georgia E. Haggard, R. Coleman Lindsley, Benjamin L. Ebert, Charles G. Mullighan
Journal: Blood
Blood (2021) 137 (12): 1628–1640.
https://doi.org/10.1182/blood.2020009103
Published: 2021
Includes: Supplemental data
Journal Articles

NUP98-KDM5A Fusion Induces Hematopoietic Cell Proliferation and Alters Myelo-Erythropoietic Differentiation

Jonathan Miller, MD PhD, Ryan Hiltenbrand, MS, Tamara Lamprecht, BS, Aman Seth, MS, Sherif Abdelhamed, PhD, Ilaria Iacobucci, PhD, Charles G. Mullighan, MBBS, MD, Jeffery M. Klco, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3775.
https://doi.org/10.1182/blood-2019-130768
Published: 2019
Journal Articles

Multiplex CRISPR/Cas9-Based Genome Editing of Mouse Hematopoietic Stem Cells Recapitulates Acute Erythroid Leukemia and Identifies Therapeutic Targets

Ilaria Iacobucci, PhD, Elena Varotto, MD, Chunxu Qu, PhD, Laura Janke, DVM, PhD, Aman Seth, PhD, Anang Shelat, PhD, Burgess Freeman, PhD, James Kennedy, Adam S Sperling, MD PhD, R. Coleman Lindsley, MD PhD, Kirsten Dickerson, BS, Debbie Payne-Turner, Sarah M Morris, Nina Ghosn, Benjamin L. Ebert, MDPhD, Charles G. Mullighan, MBBS, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5.
https://doi.org/10.1182/blood-2018-99-118817
Published: 2018
Journal Articles

ETV6-NTRK3 induces aggressive acute lymphoblastic leukemia highly sensitive to selective TRK inhibition

Kathryn G. Roberts, Laura J. Janke, Yaqi Zhao, Aman Seth, Jing Ma, David Finkelstein, Steve Smith, Kevin Ebata, Brian B. Tuch, Stephen P. Hunger, Charles G. Mullighan
Journal: Blood
Blood (2018) 132 (8): 861–865.
https://doi.org/10.1182/blood-2018-05-849554
Published: 2018
Includes: Supplemental data
Journal Articles

CREBBP Histone Acetyltransferase Domain Mutations Result in Dexamethasone Resistance in B-Progenitor Acute Lymphoblastic Leukemia

Yunchao Chang, PhD, David W. Woessner, PhD MS, Wenwei Lin, PhD, Taosheng Chen, PhD, Beisi Xu, PhD, Yiping Fan, PhD, Haiyan Tan, PhD, Junmin Peng, PhD, Lawryn Kasper, PhD, Michelle L. Churchman, PhD, Mignon L. Loh, MD, Stephen P. Hunger, MD, Aman Seth, PhD, Karen Gascoigne, PhD, Paul K Brindle, PhD, Charles G. Mullighan, MBBS, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 560.
https://doi.org/10.1182/blood.V130.Suppl_1.560.560
Published: 2017
Journal Articles

Bidirectional immune tolerance in nonmyeloablative MHC-mismatched BMT for murine β-thalassemia

Shuyu E, Aman Seth, Peter Vogel, Matt Sommers, Taren Ong, Asha B. Pillai
Journal: Blood
Blood (2017) 129 (22): 3017–3030.
https://doi.org/10.1182/blood-2016-03-704387
Published: 2017
Includes: Supplemental data
Journal Articles

An Evaluation of the Cytotoxic Effect of the Natural Product Aaptamine Against t(4;11) Leukemias

Chandrima Sinha, PhD, John Bowling, PhD, Aman Seth, MS, Bensheng Ju, PhD, Bhaskar Kahali, PhD, Mark Hamann, PhD, Lea C. Cunningham, MD
Journal: Blood
Blood (2016) 128 (22): 1624.
https://doi.org/10.1182/blood.V128.22.1624.1624
Published: 2016