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Journal Articles

Phase 2 Study of CPX-351 in Combination with Venetoclax in Patients with Newly Diagnosed, High Risk Acute Myeloid Leukemia

Wei-Ying Jen, Courtney D. DiNardo, Kelly S. Chien, Yesid Alvarado-Valero, Lucia Masarova, Mark Brandt, Debra Bull-Linderman, Naval Daver, Guillermo Montalban-Bravo, Alex Bataller, Guillermo Garcia-Manero, Ghayas C. Issa, Amin Alousi, Nicholas J. Short, Farhad Ravandi, Tapan M. Kadia
Journal: Blood
Blood (2023) 142 (Supplement 1): 4273.
https://doi.org/10.1182/blood-2023-182969
Published: 2023
Journal Articles

Venetoclax Added to Cladribine (CLAD) + Low Dose AraC (LDAC) Alternating with Azacitidine (AZA) Is Highly Active As Frontline Therapy in Older Patients with Newly Diagnosed Acute Myeloid Leukemia in a Phase 2 Study

Patrick K Reville, Hagop Kantarjian, Gautam Borthakur, Naveen Pemmaraju, Naval Daver, Courtney D. DiNardo, Koji Sasaki, Nicholas Short, Ghayas C. Issa, Maro Ohanian, Elias Jabbour, Guillermo Montalban-Bravo, Abhishek Maiti, Nitin Jain, Alessandra Ferrajoli, Kapil N. Bhalla, Koichi Takahashi, Caitlin R. Rausch, Danielle Hammond, Rashmi Malla, Kelly Quagliato, Mark Brandt, Uday R Popat, Marina Konopleva, Guillermo Garcia-Manero, Farhad Ravandi, Tapan M. Kadia
Journal: Blood
Blood (2022) 140 (Supplement 1): 9041–9043.
https://doi.org/10.1182/blood-2022-168029
Published: 2022
Journal Articles

Phase II Study of Venetoclax Added to Cladribine (CLAD) and Low Dose AraC (LDAC) Alternating with 5-Azacytidine (AZA) in Older and Unfit Patients with Newly Diagnosed Acute Myeloid Leukemia (AML)

Patrick K Reville, Hagop Kantarjian, Gautam Borthakur, Naveen Pemmaraju, Courtney D. DiNardo, Koji Sasaki, Naval Daver, Ghayas C. Issa, Maro Ohanian, Guillermo Montalban-Bravo, Nicholas J. Short, Nitin Jain, Kapil N. Bhalla, Elias J. Jabbour, Alessandra Ferrajoli, Koichi Takahashi, Caitlin R. Rausch, Rashmi Malla, Kelly Marek, Mark Brandt, Uday R. Popat, Michael Andreeff, Guillermo Garcia-Manero, Marina Konopleva, Farhad Ravandi, Tapan M. Kadia
Journal: Blood
Blood (2021) 138 (Supplement 1): 367.
https://doi.org/10.1182/blood-2021-147360
Published: 2021
Journal Articles

Phase II Study of Venetoclax Added to Cladribine + Low Dose AraC (LDAC) Alternating with 5-Azacytidine Demonstrates High Rates of Minimal Residual Disease (MRD) Negative Complete Remissions (CR) and Excellent Tolerability in Older Patients with Newly Diagnosed Acute Myeloid Leukemia (AML)

Tapan M. Kadia, MD, Gautam Borthakur, MD, Naveen Pemmaraju, MD, Naval Daver, MD, Courtney D. DiNardo, MD MSCE, Koji Sasaki, MD, Ghayas C. Issa, MD, Maro Ohanian, DO, Guillermo Montalban Bravo, MD, Nicholas J. Short, MD, Nitin Jain, MD, Alessandra Ferrajoli, MD, Kapil N. Bhalla, MD, Elias Jabbour, MD, Rashmi Kanagal-Shamanna, MD, Koichi Takahashi, MD PhD, Rashmi Malla, RN, BSN, Kelly Marek, Mark Brandt, BS, Uday R. Popat, MD, Michael Andreeff, MD PhD, Jorge E. Cortes, MD, Guillermo Garcia-Manero, MD, Marina Konopleva, MD PhD, Farhad Ravandi, MBBS, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17–19.
https://doi.org/10.1182/blood-2020-142092
Published: 2020
Journal Articles

Baseline Mutations Lack Impact on Clinical Outcomes and Molecular Response in Core Binding Factor Leukemia Treated with Highly Effective Regimen

Gautam Borthakur, MD, Tapan M. Kadia, MD, Guillermo Garcia-Manero, MD, Naveen Pemmaraju, MD, Naval Daver, MD, Courtney D. DiNardo, MD MSCE, Koichi Takahashi, MD PhD, Elias Jabbour, MD, Maro Ohanian, DO, Guillermo Montalban Bravo, MD, Farhad Ravandi, MBBS, Hagop M. Kantarjian, MD, Keyur P. Patel, MBBS, PhD, Mark Brandt, BS
Journal: Blood
Blood (2020) 136 (Supplement 1): 36–37.
https://doi.org/10.1182/blood-2020-142254
Published: 2020
Journal Articles

Urgent Cytoreductive Chemotherapy for Newly Diagnosed Patients with AML Is Safe and Feasible and Facilitates Enrollment on Investigational Clinical Trials

Kunhwa Kim, MDMPH, Marina Konopleva, MD PhD, Courtney D. DiNardo, MD MSCE, Gautam Borthakur, MD, Guillermo Garcia-Manero, MD, Naveen Pemmaraju, MD, Naval Daver, MD, Elias Jabbour, MD, Steven M. Kornblau, MD, Musa Yilmaz, MD, Maro Ohanian, DO, Alessandra Ferrajoli, MD, Nitin Jain, MD, Nicholas J. Short, MD, Caitlin R. Rausch, PharmD, Mark Brandt, BS, Sherry A. Pierce, BSN, BA, Zeev E. Estrov, MD, Farhad Ravandi, MBBS, Hagop M. Kantarjian, MD, Tapan M. Kadia, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 2–4.
https://doi.org/10.1182/blood-2020-142041
Published: 2020
Journal Articles

Azacitidine (AZA) with Nivolumab (Nivo), and AZA with Nivo + Ipilimumab (Ipi) in Relapsed/Refractory (R/R) Acute Myeloid Leukemia: Clinical and Immune Biomarkers of Response

Naval Daver, MD, Sreyashi Basu, PhD, Guillermo Garcia-Manero, MD, Hussein A Abbas, MDPhD, Marina Konopleva, MD PhD, Tapan M. Kadia, MD, Courtney D. DiNardo, MD MSCE, Gautam Borthakur, MD, Ahmad S. Alotaibi, MD, Naveen Pemmaraju, MD, Elias Jabbour, MD, Sherry A. Pierce, BSN, BA, Mark Brandt, BS, Koichi Takahashi, MD PhD, Jing Ning, Steven M. Kornblau, MD, Koji Sasaki, MD, Musa Yilmaz, MD, Ghayas C. Issa, MD, Nicholas J. Short, MD, Jairo A. Matthews, Wilmer Flores, Michael Andreeff, MD PhD, Jorge E. Cortes, MD, Farhad Ravandi, MBBS, James P Allison, PhD, Hagop M. Kantarjian, MD, Padmanee Sharma
Journal: Blood
Blood (2020) 136 (Supplement 1): 43–45.
https://doi.org/10.1182/blood-2020-142824
Published: 2020
Journal Articles

Fludarabine, Cytarabine, G-CSF and Gemtuzumab Ozogamicin (FLAG-GO) Regimen Results in Better Molecular Response and Relapse-Free Survival in Core Binding Factor Acute Myeloid Leukemia Than FLAG and Idarubicin (FLAG-Ida)

Gautam M. Borthakur, MD, Jorge E. Cortes, MD, Farhad Ravandi, MD, Guillermo Garcia-Manero, MD, Tapan M. Kadia, MD, Elias Jabbour, MD, Keyur Patel, MD PhD, Ghayas C. Issa, MD, Naval G. Daver, MD, Maro N. Ohanian, DO, Mark Brandt, BS, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 290.
https://doi.org/10.1182/blood-2019-126014
Published: 2019
Journal Articles

Nivolumab (Nivo) with Azacytidine (AZA) in Patients (pts) with Relapsed Acute Myeloid Leukemia (AML) or Frontline Elderly AML

Naval Daver, MD, Guillermo Garcia-Manero, MD, Sreyashi Basu, Jorge E. Cortes, MD, Farhad Ravandi, MBBS, Elias J. Jabbour, MD, Rita Assi, MD, Mark Brandt, BS, Sherry Pierce, BSN, BA, Tauna Gordon, Naveen Pemmaraju, MD, Michael Andreeff, MD PhD, Jing Ning, PhD, Steven Kornblau, MD, Tapan Kadia, MD, Wilmer Flores, Jairo Matthews, BA, Courtney D. DiNardo, MDMSc, Gautam Borthakur, MD, Marina Konopleva, MD PhD, James Allison, PhD, Padmanee Sharma, MD PhD, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1345.
https://doi.org/10.1182/blood.V130.Suppl_1.1345.1345
Published: 2017
Journal Articles

Long-Term Outcomes in Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Naveen Pemmaraju, MD, Hagop M. Kantarjian, MD, Joseph David Khoury, MD, Susan M. O'Brien, MD, Jorge E. Cortes, MD, Guillermo Garcia-Manero, MD, Elias J. Jabbour, MD, Nitin Jain, MD, Yesid Alvarado, MD, Madeleine Duvic, MD, Phyu Aung, MD, Muzaffar H. Qazilbash, MD, C. Cameron Yin, MD PhD, Sergej Naumovich Konoplev, MD PhD, Keyur P. Patel, MBBS, PhD, Sherry Pierce, BSN, BA, Mark Brandt, BS, Marina Konopleva, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3855.
https://doi.org/10.1182/blood.V130.Suppl_1.3855.3855
Published: 2017
Journal Articles

Phase II Study of CPX-351 (Cytarabine: Daunorubicin) Liposome Injection in Patients (Pts) with Newly Diagnosed Acute Myeloid Leukemia (AML) at High Risk for Induction Mortality

Gautam Borthakur, MD, Hagop M. Kantarjian, MD, Courtney D. DiNardo, MDMSc, Naval Daver, MD, Elias J. Jabbour, MD, Tapan Kadia, MD, Guillermo Garcia-Manero, MD, Farhad Ravandi, MBBS, Naveen Pemmaraju, MD, Marina Konopleva, MD PhD, Maro Ohanian, DO, William G Wierda, MD PhD, Nitin Jain, MD, Lian-Chun Xiao, Paromita Mukherjee, Mark Brandt, Jorge E. Cortes, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 892.
https://doi.org/10.1182/blood.V130.Suppl_1.892.892
Published: 2017
Journal Articles

Phase 2 Study of Combination of Cytarabine, Idarubicin, and Nivolumab for Initial Therapy of Patients with Newly Diagnosed Acute Myeloid Leukemia

Farhad Ravandi, MBBS, Naval Daver, MD, Guillermo Garcia-Manero, MD, Christopher B Benton, MD, Philip A Thompson, MBBS, Gautam Borthakur, MD, Tapan Kadia, MD, Prajwal C Boddu, MD, Yesid Alvarado, MD, Elias J. Jabbour, MD, Marina Konopleva, MD PhD, Koichi Takahashi, MD, Steven Kornblau, MD, Courtney D. DiNardo, MDMSc, Zeev Estrov, MD, Wilmer Flores, Sreyashi Basu, James Allison, PhD, Padmanee Sharma, MD PhD, Sherry Pierce, Mark Brandt, Allison Pike, RN, Jorge E. Cortes, MD, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 815.
https://doi.org/10.1182/blood.V130.Suppl_1.815.815
Published: 2017
Journal Articles

Response Kinetics and Factors Predicting Survival Among Patients with Core Binding Factor (CBF) Acute Myeloid Leukemia (AML)

Prajwal Boddu, MD, Christopher Gurguis, MS, Jorge E. Cortes, MD, Mary Akosile, Farhad Ravandi, MBBS, David Sanford, MD, Mark Brandt, BS, Rita Maduike, Tapan Kadia, MD, Hagop M. Kantarjian, MD, Gautam Borthakur, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 27.
https://doi.org/10.1182/blood.V130.Suppl_1.27.27
Published: 2017
Journal Articles

The Combination of Ruxolitinib (RUX) with Decitabine (DAC) in Patients (Pts) with Post-Myeloproliferative Neoplasm Acute Myeloid Leukemia (post-MPN AML): Interim Report of a Phase I/II Trial

Rita Assi, MD, Prithviraj Bose, MD, Srdan Verstovsek, MD PhD, Yvonne Gasior, RN, Nitin Jain, MD, Elias J. Jabbour, MD, Zeev Estrov, MD, Yesid Alvarado, MD, Courtney D. DiNardo, MDMSc, Naveen Pemmaraju, MD, Steven Kornblau, MD, Tapan Kadia, MD, Naval Daver, MD, Mark Brandt, BS, Sherry Pierce, BSN, BA, Xuelin Huang, PhD, Guillermo Garcia-Manero, MD, Hagop M. Kantarjian, MD, Farhad Ravandi, MBBS
Journal: Blood
Blood (2017) 130 (Supplement 1): 1379.
https://doi.org/10.1182/blood.V130.Suppl_1.1379.1379
Published: 2017
Journal Articles

Long-term outcome of acute promyelocytic leukemia treated with all- trans -retinoic acid, arsenic trioxide, and gemtuzumab

Clinical Trials & Observations
Yasmin Abaza, Hagop Kantarjian, Guillermo Garcia-Manero, Elihu Estey, Gautam Borthakur, Elias Jabbour, Stefan Faderl, Susan O’Brien, William Wierda, Sherry Pierce, Mark Brandt, Deborah McCue, Rajyalakshmi Luthra, Keyur Patel, Steven Kornblau, Tapan Kadia, Naval Daver, Courtney DiNardo, Nitin Jain, Srdan Verstovsek, Alessandra Ferrajoli, Michael Andreeff, Marina Konopleva, Zeev Estrov, Maria Foudray, David McCue, Jorge Cortes, Farhad Ravandi
Journal: Blood
Blood (2017) 129 (10): 1275–1283.
https://doi.org/10.1182/blood-2016-09-736686
Published: 2017
Journal Articles

Combination of Sorafenib and 5-Azacytidine in Older Patients with Untreated Acute Myeloid Leukemia with FLT3 -ITDmutation

Maro Ohanian, DO, Guillermo Garcia-Manero, MD, Elias J. Jabbour, MD, Naval Daver, MD, Gautam Borthakur, MD, Tapan M. Kadia, MD, Mark Brandt, BS, Sherry Pierce, BSN, BA, Jan Burger, MD PhD, Mary Ann Richie, Keyur Patel, MD, Jorge E. Cortes, MD, Hagop M. Kantarjian, MD, Farhad Ravandi, MD
Journal: Blood
Blood (2016) 128 (22): 1611.
https://doi.org/10.1182/blood.V128.22.1611.1611
Published: 2016
Journal Articles

Updated Results of a Randomized Phase II Trial of Idarubicin and Cytarabine with Clofarabine or Fludarabine in Patients with Newly Diagnosed Acute Myeloid Leukemia

Nicholas J. Short, MD, Farhad Ravandi, MD, Xuelin Huang, PhD, Jorge E. Cortes, MD, Naveen Pemmaraju, MD, Naval Daver, MD, Rita B. Khouri, Gautam Borthakur, MD, Nitin Jain, MD, Marina Konopleva, MD PhD, Zeev Estrov, MD, Guillermo Garcia-Manero, MD, Tapan M. Kadia, MD, William G. Wierda, MD PhD, Courtney D DiNardo, MD, Susan M. O'Brien, MD, Syed Shah, Allison Pike, RN, Mark Brandt, BS, Hagop M. Kantarjian, MD, Elias J. Jabbour, MD
Journal: Blood
Blood (2016) 128 (22): 1067.
https://doi.org/10.1182/blood.V128.22.1067.1067
Published: 2016
Journal Articles

Phase I/II Study of Ruxolitinib (RUX) with Decitabine (DAC) in Patients with Post-Myeloproliferative Neoplasm Acute Myeloid Leukemia (post-MPN AML): Phase I Results

Prithviraj Bose, MD, Srdan Verstovsek, MD PhD, Yvonne Gasior, Nitin Jain, MD, Elias J. Jabbour, MD, Zeev Estrov, MD, Yesid Alvarado, MD, Courtney D. DiNardo, MD MSCE, Naveen Pemmaraju, MD, Steven M. Kornblau, MD, Tapan M. Kadia, MD, Naval G. Daver, MD, Mark Brandt, BS, Sherry Pierce, BSN, BA, Graciela M. Nogueras-Gonzalez, Xuelin Huang, PhD, Guillermo Garcia-Manero, MD, Hagop M. Kantarjian, MD, Farhad Ravandi, MD
Journal: Blood
Blood (2016) 128 (22): 4262.
https://doi.org/10.1182/blood.V128.22.4262.4262
Published: 2016
Journal Articles

A Phase II Clinical Trial of Azacitidine and Vorinostat for Patients with Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS) with Poor Performance Status, Comorbidities, Other Active Malignancies or Organ Dysfunction Not Eligible for Conventional Clinical Trials

Guillermo Montalban-Bravo, MD, Xuelin Huang, PhD, Elias J. Jabbour, MD, Gautam Borthakur, MD, Courtney D. DiNardo, MD MSCE, Naveen Pemmaraju, MD, Jorge E. Cortes, MD, Srdan Verstovsek, MD PhD, Tapan M. Kadia, MD, Naval G. Daver, MD, William G. Wierda, MD PhD, Yesid Alvarado, MD, Marina Konopleva, MD PhD, Farhad Ravandi, MD, Zeev Estrov, MD, Nitin Jain, MD, Ana Alfonso Pierola, MD PhD, Mark Brandt, BS, Troy Sneed, Hsiang-Chun Chen, Hui Yang, MD PhD, Carlos E Bueso-Ramos, MD PhD, Sherry Pierce, BSN, BA, Elihu H. Estey, MD, Zachary S. Bohannan, MA, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD
Journal: Blood
Blood (2016) 128 (22): 1999.
https://doi.org/10.1182/blood.V128.22.1999.1999
Published: 2016
Journal Articles

The Impact of 20q Deletion on Clinical Presentation, Treatment Response and Survival in Patients with Acute Myeloid Leukemia (AML): The University of Texas MD Anderson Cancer Center Experience

Jad Chahoud, MD, Hagop M. Kantarjian, MD, Farhad Ravandi, MD, Koji Sasaki, MD, Guillermo Garcia-Manero, MD, Jorge E. Cortes, MD, Tapan Kadia, MD, Mark Brandt, BS, Elias Jabbour
Journal: Blood
Blood (2015) 126 (23): 1369.
https://doi.org/10.1182/blood.V126.23.1369.1369
Published: 2015