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Zeev Estrov
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Journal Articles

Ibrutinib, Fludarabine, Cyclophosphamide and Obinutuzumab (iFCG) for Firstline Treatment of Patients with CLL with Mutated IGHV and without Del(17p)/ TP53 Mutation: Six-Year Follow-up Analyses

Nitin Jain, Philip Thompson, Akhil Jain, Jan A. Burger, Alessandra Ferrajoli, Jayastu Senapati, Koichi Takahashi, Mahesh Swaminathan, Zeev Estrov, Gautam Borthakur, Prithviraj Bose, Tapan M. Kadia, Naveen Pemmaraju, Koji Sasaki, Divyam Bansal, Marina Y. Konopleva, Elias Jabbour, Naveen Garg, Xuemei Wang, Rashmi Kanagal-Shamanna, Keyur P. Patel, Wei Wang, Sa A. Wang, Jeffrey L. Jorgensen, Wanda Lopez, Ana Ayala, William Plunkett, Varsha Gandhi, Hagop M. Kantarjian, Susan M. O'Brien, Michael J. Keating, William G. Wierda
Journal: Blood
Blood (2023) 142 (Supplement 1): 3267.
https://doi.org/10.1182/blood-2023-188084
Published: 2023
Journal Articles

CLL Cell-Derived Exosomes Impair Immune Function and Normal Hematopoiesis in CLL

Ivo Veletic, David M. Harris, Uri Rozovski, Ping Li, Zhiming Liu, Taghi Manshouri, Maria Teresa S. Bertilaccio, George A. Calin, Rares-Constantin Drula, Koichi Takahashi, Ken Furudate, Muharrem Muftuoglu, Anwar Hossain, Alessandra Ferrajoli, Jan A. Burger, Nitin Jain, William G. Wierda, Srdan Verstovsek, Michael J. Keating, Zeev Estrov
Journal: Blood
Blood (2023) 142 (Supplement 1): 3264.
https://doi.org/10.1182/blood-2023-190712
Published: 2023
Journal Articles

Neoplastic Monocyte-Derived Fibrocytes Induce Bone Marrow Fibrosis in Patients with Primary Myelofibrosis

Ivo Veletic, Taghi Manshouri, Christopher D. Pacheco, C. Cameron Yin, Ying Zhang, Ping Li, Evan N. Cohen, Javier A. Gomez, Jared K. Burks, Srdan Verstovsek, Zeev Estrov
Journal: Blood
Blood (2023) 142 (Supplement 1): 4516.
https://doi.org/10.1182/blood-2023-191024
Published: 2023
Journal Articles

Results of a Phase 1/2 Study of Lower Dose CPX-351 for Patients with Int-2 or High Risk IPSS Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia after Failure to Hypomethylating Agents

Guillermo Montalban-Bravo, Elias Jabbour, Kelly S. Chien, Gautam Borthakur, Zeev Estrov, Tapan M. Kadia, Farhad Ravandi, Naveen Pemmaraju, Graciela Nogueras-Gonzalez, Heather Schneider, Rosmy John, Meghan Anne Meyer, Hagop M. Kantarjian, Guillermo Garcia-Manero, Xiao Qin DONG
Journal: Blood
Blood (2023) 142 (Supplement 1): 1873.
https://doi.org/10.1182/blood-2023-178110
Published: 2023
Journal Articles

Combined Ibrutinib and Venetoclax for First-Line Treatment of Patients with Chronic Lymphocytic Leukemia (CLL): 5-Year Follow-up Data

Nitin Jain, Michael J. Keating, Philip A. Thompson, Alessandra Ferrajoli, Jayastu Senapati, Jan A. Burger, Gautam Borthakur, Mahesh Swaminathan, Koichi Takahashi, Zeev Estrov, Marina Y. Konopleva, Koji Sasaki, Tapan M. Kadia, Naveen Pemmaraju, Naval Daver, Elias Jabbour, Courtney D. DiNardo, Yesid Alvarado Valero, Musa Yilmaz, Prithviraj Bose, Maro Ohanian, Rashmi Kanagal-Shamanna, Keyur Patel, Jeffrey L. Jorgensen, Sa A. Wang, Sameh Nassar, Naveen Garg, Hyunsoo Hwang, Xuemei Wang, Nichole Cruz, Ana Ayala, William Plunkett, Hagop M. Kantarjian, Varsha Gandhi, William G. Wierda
Journal: Blood
Blood (2023) 142 (Supplement 1): 4635.
https://doi.org/10.1182/blood-2023-189711
Published: 2023
Journal Articles

Achieving complete remission in CLL patients treated with ibrutinib: clinical significance and predictive factors

Clinical Trials & Observations
Paolo Strati, Ellen J. Schlette, Luisa M. Solis Soto, Daniela E. Duenas, Mariela Sivina, Ekaterina Kim, Michael J. Keating, William G. Wierda, Alessandra Ferrajoli, Hagop Kantarjian, Zeev Estrov, Nitin Jain, Philip A. Thompson, Ignacio I. Wistuba, Jan A. Burger
Journal: Blood
Blood (2020) 135 (7): 510–513.
https://doi.org/10.1182/blood.2019003570
Published: 2020
Journal Articles

Minimal residual disease undetectable by next-generation sequencing predicts improved outcome in CLL after chemoimmunotherapy

Clinical Trials & Observations
Philip A. Thompson, Jaya Srivastava, Christine Peterson, Paolo Strati, Jeffrey L. Jorgensen, Tyler Hether, Michael J. Keating, Susan M. O’Brien, Alessandra Ferrajoli, Jan A. Burger, Zeev Estrov, Nitin Jain, William G. Wierda
Journal: Blood
Blood (2019) 134 (22): 1951–1959.
https://doi.org/10.1182/blood.2019001077
Published: 2019
Includes: Supplemental data
Journal Articles

Myelofibrosis osteoclasts are clonal and functionally impaired

Brief Report
Ivo Veletic, Taghi Manshouri, Asha S. Multani, C. Cameron Yin, Lei Chen, Srdan Verstovsek, Zeev Estrov
Journal: Blood
Blood (2019) 133 (21): 2320–2324.
https://doi.org/10.1182/blood-2018-10-878926
Published: 2019
Includes: Supplemental data
Journal Articles

Randomized trial of ibrutinib vs ibrutinib plus rituximab in patients with chronic lymphocytic leukemia

Clinical Trials & Observations
Jan A. Burger, Mariela Sivina, Nitin Jain, Ekaterina Kim, Tapan Kadia, Zeev Estrov, Graciela M. Nogueras-Gonzalez, Xuelin Huang, Jeffrey Jorgensen, Jianling Li, Mei Cheng, Fong Clow, Maro Ohanian, Michael Andreeff, Thomas Mathew, Philip Thompson, Hagop Kantarjian, Susan O’Brien, William G. Wierda, Alessandra Ferrajoli, Michael J. Keating
Journal: Blood
Blood (2019) 133 (10): 1011–1019.
https://doi.org/10.1182/blood-2018-10-879429
Published: 2019
Includes: Supplemental data
Journal Articles

A phase 2 study of ruxolitinib in combination with azacitidine in patients with myelofibrosis

Clinical Trials & Observations
Lucia Masarova, Srdan Verstovsek, Juliana E. Hidalgo-Lopez, Naveen Pemmaraju, Prithviraj Bose, Zeev Estrov, Elias J. Jabbour, Farhad Ravandi-Kashani, Koichi Takahashi, Jorge E. Cortes, Jing Ning, Maro Ohanian, Yesid Alvarado, Lingsha Zhou, Sherry Pierce, Romany Gergis, Keyur P. Patel, Rajyalakshmi Luthra, Tapan M. Kadia, Courtney D. DiNardo, Gautam Borthakur, Kapil Bhalla, Guillermo Garcia-Manero, Carlos E. Bueso-Ramos, Hagop M. Kantarjian, Naval Daver
Journal: Blood
Blood (2018) 132 (16): 1664–1674.
https://doi.org/10.1182/blood-2018-04-846626
Published: 2018
Includes: Supplemental data
Journal Articles

Clinical implications of cancer gene mutations in patients with chronic lymphocytic leukemia treated with lenalidomide

Clinical Trials & Observations
Koichi Takahashi, Boyu Hu, Feng Wang, Yuanqing Yan, Ekaterina Kim, Candida Vitale, Keyur P. Patel, Paolo Strati, Curtis Gumbs, Latasha Little, Samantha Tippen, Xingzhi Song, Jianhua Zhang, Nitin Jain, Philip Thompson, Guillermo Garcia-Manero, Hagop Kantarjian, Zeev Estrov, Kim-Anh Do, Michael Keating, Jan A. Burger, William G. Wierda, P. Andrew Futreal, Alessandra Ferrajoli
Journal: Blood
Blood (2018) 131 (16): 1820–1832.
https://doi.org/10.1182/blood-2017-11-817296
Published: 2018
Includes: Supplemental data
Journal Articles

Non-Driver Mutations and Gene Sequence Variants Identified By Targeted Deep Sequencing in Polycythemia Vera and Essential Thrombocythemia

Prajwal Boddu, MD, Alay Mansurov, Lucia Masarova, MD, Prithviraj Bose, MD, Keyur P. Patel, MBBS, PhD, Zeev Estrov, MD, Hagop M. Kantarjian, MD, Srdan Verstovsek, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4183.
https://doi.org/10.1182/blood.V130.Suppl_1.4183.4183
Published: 2017
Journal Articles

Randomized Trial of Ibrutinib Versus Ibrutinib Plus Rituximab (Ib+R) in Patients with Chronic Lymphocytic Leukemia (CLL)

Jan A. Burger, MD PhD, Mariela Sivina, PhD, Alessandra Ferrajoli, MD, Nitin Jain, MD, Ekaterina Kim, PhD, Tapan Kadia, MD, Zeev Estrov, MD, Graciela Nogueras González, Xuelin Huang, PhD, Maro Ohanian, DO, Michael Andreeff, MD PhD, Mathew Thomas, Lynette Alexander-Williams, Hagop M. Kantarjian, MD, Susan M. O'Brien, MD, William G Wierda, MD PhD, Michael J. Keating, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 427.
https://doi.org/10.1182/blood.V130.Suppl_1.427.427
Published: 2017
Journal Articles

Myelofibrosis (MF) Leukemic Transformation (LT) in the Era of Ruxolitinib and Genomics: Characteristics and Outcomes

Lorenzo Falchi, MD, Dai Chihara, MDPhD, Prithviraj Bose, MD, Zeev Estrov, MD, Hagop M. Kantarjian, MD, Farhad Ravandi, MBBS, Srdan Verstovsek, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4185.
https://doi.org/10.1182/blood.V130.Suppl_1.4185.4185
Published: 2017
Journal Articles

Combined Venetoclax and Ibrutinib for Patients with Previously Untreated High-Risk CLL, and Relapsed/Refractory CLL: A Phase II Trial

Nitin Jain, MD, Philip A Thompson, MBBS, Alessandra Ferrajoli, MD, Jan A. Burger, MD PhD, Gautam Borthakur, MD, Koichi Takahashi, MD, Prithviraj Bose, MD, Zeev Estrov, MD, Elias J. Jabbour, MD, Marina Konopleva, MD PhD, Yesid Alvarado, MD, Tapan Kadia, MD, Musa Yilmaz, MD, Courtney D. DiNardo, MDMSc, Maro Ohanian, DO, Jorge E. Cortes, MD, Rashmi Kanagal-Shamanna, MD, Keyur Patel, MD PhD, Naveen Garg, MD, Xuemei Wang, Nina Fru, RN, Nichole Cruz, RN, Varsha Gandhi, PhD, William Plunkett, PhD, Hagop M. Kantarjian, MD, Michael J. Keating, MD, William G Wierda, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 429.
https://doi.org/10.1182/blood.V130.Suppl_1.429.429
Published: 2017
Journal Articles

Validation of the Myelofibrosis Secondary to PV and ET-Prognostic Model in Patients with Post-Polycythemia Vera and Post-Essential Thrombocythemia Myelofibrosis: MD Anderson Cancer Center

Lucia Masarova, MD, Prithviraj Bose, MD, Naveen Pemmaraju, MD, Naval Daver, MD, Jorge E. Cortes, MD, Zeev Estrov, MD, Hagop M. Kantarjian, MD, Srdan Verstovsek, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4205.
https://doi.org/10.1182/blood.V130.Suppl_1.4205.4205
Published: 2017
Journal Articles

The Combination of Quizartinib with Azacitidine or Low Dose Cytarabine Is Highly Active in Patients (Pts) with FLT3-ITD Mutated Myeloid Leukemias: Interim Report of a Phase I/II Trial

Mahesh Swaminathan, MD, Hagop M. Kantarjian, MD, Naval Daver, MD, Gautam Borthakur, MD, Maro Ohanian, DO, Tapan Kadia, MD, Courtney D. DiNardo, MDMSc, Nitin Jain, MD, Zeev Estrov, MD, Alessandra Ferrajoli, MD, Guillermo Garcia-Manero, MD, Marina Konopleva, MD PhD, Michael Andreeff, MD PhD, Naveen Pemmaraju, MD, Elias J. Jabbour, MD, William G Wierda, MD PhD, Farhad Ravandi, MBBS, Maria Rhona Pinsoy, Jorge E. Cortes, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 723.
https://doi.org/10.1182/blood.V130.Suppl_1.723.723
Published: 2017
Journal Articles

Phase 2 Study of Combination of Cytarabine, Idarubicin, and Nivolumab for Initial Therapy of Patients with Newly Diagnosed Acute Myeloid Leukemia

Farhad Ravandi, MBBS, Naval Daver, MD, Guillermo Garcia-Manero, MD, Christopher B Benton, MD, Philip A Thompson, MBBS, Gautam Borthakur, MD, Tapan Kadia, MD, Prajwal C Boddu, MD, Yesid Alvarado, MD, Elias J. Jabbour, MD, Marina Konopleva, MD PhD, Koichi Takahashi, MD, Steven Kornblau, MD, Courtney D. DiNardo, MDMSc, Zeev Estrov, MD, Wilmer Flores, Sreyashi Basu, James Allison, PhD, Padmanee Sharma, MD PhD, Sherry Pierce, Mark Brandt, Allison Pike, RN, Jorge E. Cortes, MD, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 815.
https://doi.org/10.1182/blood.V130.Suppl_1.815.815
Published: 2017
Journal Articles

A Phase I/II Study of Inotuzumab Ozogamicin in Combination with Low-Intensity Chemotherapy (mini-hyper-CVD) for Older Patients with Newly Diagnosed Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia

Nicholas J Short, MD, Hagop M. Kantarjian, MD, Farhad Ravandi, MBBS, Xuelin Huang, PhD, Nitin Jain, MD, Naval Daver, MD, Deborah A Thomas, MD, Naveen Pemmaraju, MD, Rita Khouri, Joseph David Khoury, MD, Jeffrey L. Jorgensen, MD PhD, Yesid Alvarado, MD, Koji Sasaki, MD, Marina Konopleva, MD PhD, Guillermo Garcia-Manero, MD, Tapan Kadia, MD, Jorge E. Cortes, MD, Christopher B Benton, MD, Gautam Borthakur, MD, Jan A. Burger, MD PhD, Maro Ohanian, DO, William G Wierda, MD PhD, Zeev Estrov, MD, Steven Kornblau, MD, Courtney D. DiNardo, MDMSc, Alessandra Ferrajoli, MD, Jovitta Jacob, RN, Ameena Manzoor, Rebecca Garris, Msc, Susan M. O'Brien, MD, Elias J. Jabbour, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2576.
https://doi.org/10.1182/blood.V130.Suppl_1.2576.2576
Published: 2017
Journal Articles

A Randomized Phase II Trial of 5-Day Versus 10-Day Schedules of Decitabine for Older Patients with Previously Untreated Acute Myeloid Leukemia

Nicholas J Short, MD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD, Gautam Borthakur, MD, Tapan Kadia, MD, Xuelin Huang, PhD, Naval Daver, MD, Courtney D. DiNardo, MDMSc, Alessandra Ferrajoli, MD, William G Wierda, MD PhD, Zeev Estrov, MD, Christopher B Benton, MD, Prithviraj Bose, MD, Yesid Alvarado, MD, Steven Kornblau, MD, Maro Ohanian, DO, Yvonne Gaisor, Mary Ann Richie, Sherry Pierce, Elias J. Jabbour, MD, Jorge E. Cortes, MD, Farhad Ravandi, MBBS
Journal: Blood
Blood (2017) 130 (Supplement 1): 2577.
https://doi.org/10.1182/blood.V130.Suppl_1.2577.2577
Published: 2017