Page 1 | Search Results | Blood | American Society of Hematology

1-20 of 31

Sort by

Sort Order Select

Journal Articles

PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371

Blood (2023) 141 (3): 244–259.

https://doi.org/10.1182/blood.2022016580

Published: 2023

Includes: Supplemental data

Journal Articles

SLFN11 Is a Potential Biomarker and Modulator of Treatment Response in AML

Sara Small, Mariafausta Fischietti, Elspeth Beauchamp, Ricardo Ernesto Perez, Leonidas C. Platanias

Blood (2022) 140 (Supplement 1): 9098–9099.

https://doi.org/10.1182/blood-2022-162444

Published: 2022

Journal Articles

Synthetic Lipid Nanoparticles Actively Target Acute Myeloid Leukemia (AML) Cells and Induce Ferroptosis through Decreased Expression of Glutathione Peroxidase 4

Adam Yuh Lin, Jonathan Scott Rink, Eva Yang, Sara Small, Fransheska Serrano, Yasmin Abaza, Jessica K. Altman, Leonidas C. Platanias, Colby Shad Thaxton, Leo I. Gordon

Blood (2022) 140 (Supplement 1): 5967–5968.

https://doi.org/10.1182/blood-2022-168154

Published: 2022

Journal Articles

Identification and targeting of novel CDK9 complexes in acute myeloid leukemia

Elspeth M. Beauchamp, Sameem M. Abedin, Sara G. Radecki, Mariafausta Fischietti, Ahmet Dirim Arslan, Gavin T. Blyth, Angela Yang, Connor Lantz, Alissa Nelson, Young Ah Goo, Imo Akpan, Elizabeth A. Eklund, Olga Frankfurt, Eleanor N. Fish, Paul M. Thomas, Jessica K. Altman, Leonidas C. Platanias

Blood (2019) 133 (11): 1171–1185.

https://doi.org/10.1182/blood-2018-08-870089

Published: 2019

Includes: Supplemental data

Journal Articles

Merestinib blocks Mnk kinase activity in acute myeloid leukemia progenitors and exhibits antileukemic effects in vitro and in vivo

Ewa M. Kosciuczuk, Diana Saleiro, Barbara Kroczynska, Elspeth M. Beauchamp, Frank Eckerdt, Gavin T. Blyth, Sameem M. Abedin, Francis J. Giles, Jessica K. Altman, Leonidas C. Platanias

Blood (2016) 128 (3): 410–414.

https://doi.org/10.1182/blood-2016-02-698704

Published: 2016

Includes: Supplemental data

Journal Articles

AZD1208, a potent and selective pan-Pim kinase inhibitor, demonstrates efficacy in preclinical models of acute myeloid leukemia

Blood (2014) 123 (6): 905–913.

https://doi.org/10.1182/blood-2013-04-495366

Published: 2014

Includes: Supplemental data

Journal Articles

Inhibition of Mnk kinase activity by cercosporamide and suppressive effects on acute myeloid leukemia precursors

Jessica K. Altman, Amy Szilard, Bruce W. Konicek, Philip W. Iversen, Barbara Kroczynska, Heather Glaser, Antonella Sassano, Eliza Vakana, Jeremy R. Graff, Leonidas C. Platanias

Blood (2013) 121 (18): 3675–3681.

https://doi.org/10.1182/blood-2013-01-477216

Published: 2013

Journal Articles

The Diterpenoid Lactone Andrographolide Induces Reactive Oxygen Species (ROS) Dependent Apoptosis in ATRA Sensitive and Resistant APL Cell Lines.

Shuo Yang, PhD, Jessica K. Altman, MD, Sheila Prachand, MS, Austin Tom, BS, Bo Ding, BS, Brent Wu, Leonidas C. Platanias, MD, PhD, Leo I. Gordon, MD

Blood (2012) 120 (21): 2446.

https://doi.org/10.1182/blood.V120.21.2446.2446

Published: 2012

Journal Articles

Autophagic degradation of the BCR-ABL oncoprotein and generation of antileukemic responses by arsenic trioxide

Dennis J. Goussetis, Elias Gounaris, Edward J. Wu, Eliza Vakana, Bhumika Sharma, Matthew Bogyo, Jessica K. Altman, Leonidas C. Platanias

Blood (2012) 120 (17): 3555–3562.

https://doi.org/10.1182/blood-2012-01-402578

Published: 2012

Includes: Supplemental data

Journal Articles

BH3 mimetics and multi-kinase inhibition in AML

Elspeth M. Beauchamp, Leonidas C. Platanias

Blood (2012) 119 (25): 5947–5948.

https://doi.org/10.1182/blood-2012-04-420786

Published: 2012

Journal Articles

Antileukemic effects of AMPK activators on BCR-ABL–expressing cells

Eliza Vakana, Jessica K. Altman, Heather Glaser, Nicholas J. Donato, Leonidas C. Platanias

Blood (2011) 118 (24): 6399–6402.

https://doi.org/10.1182/blood-2011-01-332783

Published: 2011

Includes: Supplemental data

Journal Articles

Design, Synthesis and Biological Evaluation of A Boron Containing Retinoid As a Novel Therapeutic Agent for Acute Promyelocytic Leukemia

Carolina D. Schinke, MD, Bhaskar C Das, Swati Goel, Tushar Bhagat, Sangeeta Nischal, Ph.D., Saverio Minucci, George Kabalka, B.S, PhD, Robert E. Gallagher, MD, Todd Evans, PhD, Leonidas C Platanias, MD, PhD, Amit Verma, MD

Blood (2011) 118 (21): 5008.

https://doi.org/10.1182/blood.V118.21.5008.5008

Published: 2011

Journal Articles

Abnormalities in Th17 T cells in aplastic anemia

Leonidas C. Platanias

Blood (2010) 116 (20): 4039–4040.

https://doi.org/10.1182/blood-2010-09-305367

Published: 2010

Journal Articles

Glutathione Depletion Enhances Arsenic Trioxide-Induced Apoptosis in Lymphoma Cells through Mitochondrial and Caspase-Independent Mechanisms.

Savita Bhalla, PhD, Leo I. Gordon, MD, Amareshwar Singh, PhD, Sheila Prachand, M.S., Shuo Yang, PhD, Jane N. Winter, MD, Dongsheng Guo, PhD, Thomas O'Halloran, PhD, Leonidas C Platanias, Andrew M. Evens, DO, MSc

Blood (2009) 114 (22): 2708.

https://doi.org/10.1182/blood.V114.22.2708.2708

Published: 2009

Journal Articles

High Prevalence of Elderly Anemia Is Seen in a Large Inner City Outpatient Population and Is Predictive of Decreased Overall Survival across All Ethnic Groups

Anthony P Lam, Jordan Golubcow-Teglasi, Krishna Gundabolu, Howard Ratech, K. H. Ramesh, Leonidas C Platanias, Ellen Friedman, Amit Verma

Blood (2008) 112 (11): 3447.

https://doi.org/10.1182/blood.V112.11.3447.3447

Published: 2008

Journal Articles

Targeting the Mnk Pathway Enhances Chemotherapy-Induced Antileukemic Responses.

Jessica K Altman, Heather Glaser, Amanda Redig, Antonella Sassano, Martin S Tallman, Leonidas C Platanias

Blood (2008) 112 (11): 1617.

https://doi.org/10.1182/blood.V112.11.1617.1617

Published: 2008

Journal Articles

Design and Synthesis of Novel Derivatives of ATRA Demonstrate the Combined Importance of Acid Moiety and Conjugated Double Bonds in Its Binding to PMLRAR-Alpha Oncogene in Acute Promyelocytic Leukemia

Swati Goel, Carolina Schinke, Tushar Bhagat, Yongkai Mo, Li Zhou, Christoph Heuck, Christina Alencar, Perry Pahanish, Jaime Anguiano, George Kabalka, Leonidas C Platanias, Amit Verma, Bhaskar Das

Blood (2008) 112 (11): 5036.

https://doi.org/10.1182/blood.V112.11.5036.5036

Published: 2008

Journal Articles

Inhibition of the TGF-β receptor I kinase promotes hematopoiesis in MDS

Blood (2008) 112 (8): 3434–3443.

https://doi.org/10.1182/blood-2008-02-139824

Published: 2008

Includes: Supplemental data

Journal Articles

CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1

Thomas T. Murooka, Ramtin Rahbar, Leonidas C. Platanias, Eleanor N. Fish

Blood (2008) 111 (10): 4892–4901.

https://doi.org/10.1182/blood-2007-11-125039

Published: 2008

Includes: Supplemental data

Journal Articles

Arsenic Trioxide (As 2 O 3 ) Mediated Cell Death in Hodgkin Lymphoma (HL) and Non-Hodgkin Lymphoma (NHL): Investigation of Reactive Oxygen Species (ROS), Caspase, and MAP Kinase Signaling Pathways.

Savita Bhalla, PhD, Amareshwar T.K Singh, PhD, Sheila Prachand, MS, Qudsia Haque, BS, Thomas V. O’Halloran, PhD, Jane N. Winter, MD, Paul T. Schumacker, PhD, Leonidas C. Platanias, MD, Leo I. Gordon, MD, Andrew M. Evens, DO, MS

Blood (2007) 110 (11): 2576.

https://doi.org/10.1182/blood.V110.11.2576.2576

Published: 2007

NARROW

PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371

SLFN11 Is a Potential Biomarker and Modulator of Treatment Response in AML

Synthetic Lipid Nanoparticles Actively Target Acute Myeloid Leukemia (AML) Cells and Induce Ferroptosis through Decreased Expression of Glutathione Peroxidase 4

Identification and targeting of novel CDK9 complexes in acute myeloid leukemia

Merestinib blocks Mnk kinase activity in acute myeloid leukemia progenitors and exhibits antileukemic effects in vitro and in vivo

AZD1208, a potent and selective pan-Pim kinase inhibitor, demonstrates efficacy in preclinical models of acute myeloid leukemia

Inhibition of Mnk kinase activity by cercosporamide and suppressive effects on acute myeloid leukemia precursors

The Diterpenoid Lactone Andrographolide Induces Reactive Oxygen Species (ROS) Dependent Apoptosis in ATRA Sensitive and Resistant APL Cell Lines.

Autophagic degradation of the BCR-ABL oncoprotein and generation of antileukemic responses by arsenic trioxide

BH3 mimetics and multi-kinase inhibition in AML

Antileukemic effects of AMPK activators on BCR-ABL–expressing cells

Design, Synthesis and Biological Evaluation of A Boron Containing Retinoid As a Novel Therapeutic Agent for Acute Promyelocytic Leukemia

Abnormalities in Th17 T cells in aplastic anemia

Glutathione Depletion Enhances Arsenic Trioxide-Induced Apoptosis in Lymphoma Cells through Mitochondrial and Caspase-Independent Mechanisms.

High Prevalence of Elderly Anemia Is Seen in a Large Inner City Outpatient Population and Is Predictive of Decreased Overall Survival across All Ethnic Groups

Targeting the Mnk Pathway Enhances Chemotherapy-Induced Antileukemic Responses.

Design and Synthesis of Novel Derivatives of ATRA Demonstrate the Combined Importance of Acid Moiety and Conjugated Double Bonds in Its Binding to PMLRAR-Alpha Oncogene in Acute Promyelocytic Leukemia

Inhibition of the TGF-β receptor I kinase promotes hematopoiesis in MDS

CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1

Arsenic Trioxide (As 2 O 3 ) Mediated Cell Death in Hodgkin Lymphoma (HL) and Non-Hodgkin Lymphoma (NHL): Investigation of Reactive Oxygen Species (ROS), Caspase, and MAP Kinase Signaling Pathways.

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only