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Saverio Minucci
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Journal Articles

Clonal evolution of acute myeloid leukemia with FLT3 -ITD mutation under treatment with midostaurin

Laura K. Schmalbrock, Anna Dolnik, Sibylle Cocciardi, Eric Sträng, Frauke Theis, Nikolaus Jahn, Ekaterina Panina, Tamara J. Blätte, Julia Herzig, Sabrina Skambraks, Frank G. Rücker, Verena I. Gaidzik, Peter Paschka, Walter Fiedler, Helmut R. Salih, Gerald Wulf, Thomas Schroeder, Michael Lübbert, Richard F. Schlenk, Felicitas Thol, Michael Heuser, Richard A. Larson, Arnold Ganser, Hendrik G. Stunnenberg, Saverio Minucci, Richard M. Stone, Clara D. Bloomfield, Hartmut Döhner, Konstanze Döhner, Lars Bullinger
Journal: Blood
Blood (2021) 137 (22): 3093–3104.
https://doi.org/10.1182/blood.2020007626
Published: 2021
Includes: Supplemental data
Journal Articles

DNA binding modes of leukemia oncoproteins

Saverio Minucci
Journal: Blood
Blood (2016) 127 (2): 177–178.
https://doi.org/10.1182/blood-2015-11-681080
Published: 2016
Journal Articles

Inhibition of the Histone Demethylase LSD1 Combined with Caloric Restriction or IGF1/Insulin Inhibition Leads to Durable Responses in a Preclinical Model of Acute Myeloid Leukemia

Luca Mazzarella, MD PhD, Tiphanie Durfort, Rani Pallavi, Elena Mylonas, Paolo Falvo, Anna Giulia Sanarico, Massimo Stendardo, Luciano Giaco', Anna Russo, Lucilla Luzi, Massimiliano Mazza, Giulia De Conti, Paola Vianello, Pier Luigi Rossi, Elena Ceccacci, Mohamed Elgendy, Marco Giorgio, Ciro Mercurio, Saverio Minucci, Pier Giuseppe Pelicci
Journal: Blood
Blood (2015) 126 (23): 459.
https://doi.org/10.1182/blood.V126.23.459.459
Published: 2015
Journal Articles

Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies

Geoffrey M. Matthews, Parinaz Mehdipour, Leonie A. Cluse, Katrina J. Falkenberg, Eric Wang, Mareike Roth, Fabio Santoro, Eva Vidacs, Kym Stanley, Colin M. House, James R. Rusche, Christopher R. Vakoc, Johannes Zuber, Saverio Minucci, Ricky W. Johnstone
Journal: Blood
Blood (2015) 126 (21): 2392–2403.
https://doi.org/10.1182/blood-2015-03-632984
Published: 2015
Includes: Supplemental data
Journal Articles

A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance

Fabio Santoro, Oronza A. Botrugno, Roberto Dal Zuffo, Isabella Pallavicini, Geoffrey M. Matthews, Leonie Cluse, Iros Barozzi, Silvia Senese, Lorenzo Fornasari, Simona Moretti, Lucia Altucci, Pier Giuseppe Pelicci, Susanna Chiocca, Ricky W. Johnstone, Saverio Minucci
Journal: Blood
Blood (2013) 121 (17): 3459–3468.
https://doi.org/10.1182/blood-2012-10-461988
Published: 2013
Includes: Supplemental data
Journal Articles

Chromatin accessibility, p300, and histone acetylation define PML-RARα and AML1-ETO binding sites in acute myeloid leukemia

Sadia Saeed, Colin Logie, Kees-Jan Francoijs, Gianmaria Frigè, Mauro Romanenghi, Fiona G. Nielsen, Lianne Raats, Maryam Shahhoseini, Martijn Huynen, Lucia Altucci, Saverio Minucci, Joost H. A. Martens, Hendrik G. Stunnenberg
Journal: Blood
Blood (2012) 120 (15): 3058–3068.
https://doi.org/10.1182/blood-2011-10-386086
Published: 2012
Includes: Supplemental data
Journal Articles

Design, Synthesis and Biological Evaluation of A Boron Containing Retinoid As a Novel Therapeutic Agent for Acute Promyelocytic Leukemia

Carolina D. Schinke, MD, Bhaskar C Das, Swati Goel, Tushar Bhagat, Sangeeta Nischal, Ph.D., Saverio Minucci, George Kabalka, B.S, PhD, Robert E. Gallagher, MD, Todd Evans, PhD, Leonidas C Platanias, MD, PhD, Amit Verma, MD
Journal: Blood
Blood (2011) 118 (21): 5008.
https://doi.org/10.1182/blood.V118.21.5008.5008
Published: 2011
Journal Articles

G1 Cell-Cycle Arrest and Apoptosis by Histone Deacetylase Inhibition in MLL-AF9 Acute Myeloid Leukemia Cells Is MLL-AF9 Independent.

Roberto Tonelli, PhD, Roberta Sartini, PhD, Raffaele Fronza, PhD, Francesca Freccero, PhD, Monica Franzoni, PhD, Danilo Dongiovanni, PhD, Marco Ballarini, PhD, Simona Ferrari, PhD, Maria D’Apolito, PhD, Gabriella Di Cola, PhD, Giovanni Capranico, PhD, Andriy Khobta, PhD, Renato Campanini, PhD, Paolo Paolucci, MD, Saverio Minucci, MD, Andrea Pession, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 4410.
https://doi.org/10.1182/blood.V106.11.4410.4410
Published: 2005
Journal Articles

Activation of the p70 S6 kinase by all- trans -retinoic acid in acute promyelocytic leukemia cells

Lakhvir Lal, Yongzhong Li, Jessica Smith, Antonella Sassano, Shahab Uddin, Simrit Parmar, Martin S. Tallman, Saverio Minucci, Nissim Hay, Leonidas C. Platanias
Journal: Blood
Blood (2005) 105 (4): 1669–1677.
https://doi.org/10.1182/blood-2004-06-2078
Published: 2005
Journal Articles

PML-RAR induces promyelocytic leukemias with high efficiency following retroviral gene transfer into purified murine hematopoietic progenitors

Saverio Minucci, Silvia Monestiroli, Sabrina Giavara, Simona Ronzoni, Francesco Marchesi, Alessandra Insinga, Daniela Diverio, Patrizia Gasparini, Manuela Capillo, Emanuela Colombo, Cristian Matteucci, Francesco Contegno, Francesco Lo-Coco, Eugenio Scanziani, Alberto Gobbi, Pier Giuseppe Pelicci
Journal: Blood
Blood (2002) 100 (8): 2989–2995.
https://doi.org/10.1182/blood-2001-11-0089
Published: 2002
Journal Articles

Constitutive Degradation of PML/RAR Through the Proteasome Pathway Mediates Retinoic Acid Resistance

Mirco Fanelli, Saverio Minucci, Vania Gelmetti, Clara Nervi, Carlo Gambacorti-Passerini, Pier Giuseppe Pelicci
Journal: Blood
Blood (1999) 93 (5): 1477–1481.
https://doi.org/10.1182/blood.V93.5.1477
Published: 1999