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Journal Articles

Spatial transcriptomic dissection of the myeloproliferative neoplasm niche uncovers mutant clone interactions and microenvironmental rewiring

Free
Honghao Bi, Pan Wang, Ching Man Wai, Kehan Ren, Xu Han, Ermin Li, Laya Soleimani, Inci Aydemir, Wenjie Cai, Johanna Melo-Cardenas, Peng Ji
Journal: Blood
Blood (2025) 146 (Supplement 1): 3761.
https://doi.org/10.1182/blood-2025-3761
Published: 2025
Journal Articles

DHODH-driven pyrimidine metabolism is a targetable vulnerability in myeloproliferative neoplasms

Free
Pan Wang, Xu Han, Inci Aydemir, Ermin Li, Honghao Bi, Kehan Ren, Wenjie Cai, Laya Soleimani, Peng Ji
Journal: Blood
Blood (2025) 146 (Supplement 1): 69.
https://doi.org/10.1182/blood-2025-69
Published: 2025
Journal Articles

Plek2 as a novel downstream effector of p53: Targeting Plek2 ameliorates disease progression in p53-deficient myeloid malignancies

Free
Pan Wang, Xu Han, Honghao Bi, Ermin Li, Kehan Ren, Inci Aydemir, Wenjie Cai, Laya Soleimani, Peng Ji
Journal: Blood
Blood (2025) 146 (Supplement 1): 216.
https://doi.org/10.1182/blood-2025-216
Published: 2025
Journal Articles

Modeling germline DDX41 and/or CHEK2 mutations using patient-derived bone marrow Organoids

Free
Inci Aydemir, Xu Han, Honghao Bi, Ermin Li, Kehan Ren, Pan Wang, Laya Soleimani, Madina Sukhanova, Lucy Godley, Peng Ji
Journal: Blood
Blood (2025) 146 (Supplement 1): 1444.
https://doi.org/10.1182/blood-2025-1444
Published: 2025
Journal Articles

Inflammatory remodeling and CD4+ T cell expansion in TET2-mutated myeloid disorders

Free
Kehan Ren, Ermin Li, Xu Han, Yijie Liu, Honghao Bi, Pan Wang, Inci Aydemir, Madina Sukhanova, Peng Ji
Journal: Blood
Blood (2025) 146 (Supplement 1): 3162.
https://doi.org/10.1182/blood-2025-3162
Published: 2025
Journal Articles

Germline DDX41 Mutations Disrupt Hematopoiesis and Microenvironment in Patient-Derived Bone Marrow Organoids

Free
Inci Aydemir, Xu Han, Honghao Bi, Ermin Li, Kehan Ren, Pan Wang, Madina Sukhanova, Lucy Godley, Peng Ji
Journal: Blood
Blood (2024) 144 (Supplement 1): 4093.
https://doi.org/10.1182/blood-2024-211026
Published: 2024
Journal Articles

Bone Marrow Microenvironment Dictates the Progression of Clonal Hematopoiesis through Stromal-Macrophage Cell-Cell Interactions

Free
Kehan Ren, Ermin Li, Xu Han, Pan Wang, Inci Aydemir, Kara Tao, Madina Sukhanova, Peng Ji
Journal: Blood
Blood (2024) 144 (Supplement 1): 821.
https://doi.org/10.1182/blood-2024-211058
Published: 2024
Journal Articles

ICAM4 Mediates Human Erythroid Centered Island Formation

Free
Xu Han, Kehan Ren, Pan Wang, Honghao Bi, Inci Aydemir, Ermin Li, Peng Ji
Journal: Blood
Blood (2024) 144 (Supplement 1): 2451.
https://doi.org/10.1182/blood-2024-204183
Published: 2024
Journal Articles

Spatial Mapping Reveals Distinct Erythroid Niches in Mice and Humans during Development and Stress

Free
Xu Han, Kehan Ren, Pan Wang, Honghao Bi, Inci Aydemir, Ermin Li, Peng Ji
Journal: Blood
Blood (2023) 142 (Supplement 1): 140.
https://doi.org/10.1182/blood-2023-181272
Published: 2023
Journal Articles

PPIL2 Is a Target of the JAK2-STAT5 Pathway and Mediates p53 Polyubiquitination and Degradation

Free
Pan Wang, Xu Han, Kehan Ren, Ermin Li, Honghao Bi, Inci Aydemir, Peng Ji
Journal: Blood
Blood (2023) 142 (Supplement 1): 4515.
https://doi.org/10.1182/blood-2023-177677
Published: 2023