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Journal Articles

RAS/RAF landscape in monoclonal plasma cell conditions

Brief Report
Anais Schavgoulidze, Jill Corre, Mehmet Kemal Samur, Celine Mazzotti, Luka Pavageau, Aurore Perrot, Titouan Cazaubiel, Xavier Leleu, Margaret Macro, Karim Belhadj, Murielle Roussel, Sabine Brechignac, Lydia Montes, Denis Caillot, Laurent Frenzel, Philippe Rey, Jean-Marc Schiano de Colella, Thomas Chalopin, Caroline Jacquet, Valentine Richez, Frederique Orsini-Piocelle, Jean Fontan, Salomon Manier, Ludovic Martinet, Adam Sciambi, Mohamad Mohty, Herve Avet-Loiseau
Journal: Blood
Blood (2024) 144 (2): 201–205.
https://doi.org/10.1182/blood.2023022295
Published: 2024
Includes: Supplemental data
Journal Articles

Teclistamab in relapsed or refractory AL amyloidosis: a multinational retrospective case series

Nathalie Forgeard, Dikélélé Elessa, Alexander Carpinteiro, Karim Belhadj, Monique Minnema, Murielle Roussel, Antoine Huart, Vincent Javaugue, Laurent Pascal, Bruno Royer, Alexis Talbot, Romain Gounot, Ute Hegenbart, Stefan Schonland, Lionel Karlin, Stéphanie Harel, Efstathios Kastritis, Frank Bridoux, Arnaud Jaccard, Bertrand Arnulf
Journal: Blood
Blood (2024) 143 (8): 734–737.
https://doi.org/10.1182/blood.2023022937
Published: 2024
Journal Articles

Ixazomib, Pomalidomide and Dexamethasone (IxPd) in Relapsed or Refractory Multiple Myeloma (RRMM) Characterized with High-Risk Cytogenetics. IFM 2014-01

Arthur Bobin, Salomon Manier, Joe De Keizer, Cyrille Hulin, Lionel Karlin, Denis Caillot, Clara Mariette, Carla Araujo, Bertrand Arnulf, Benoit Bareau, Karim Belhadj Merzoug, Lotfi Benboubker, Thorsten Braun, Claire Calmettes, Olivier Decaux, Mamoun Dib, Helene Demarquette, Pierre Feugier, Cécile Sonntag, Arnaud Jaccard, Pascal Lenain, Margaret Macro, Valentine Richez, Mourad Tiab, Laure Vincent, Hacene Zerazhi, Marie-Odile Petillon, Cyrille Touzeau, Aurore Perrot, Philippe Moreau, Thierry Facon, Herve Avet Loiseau, Xavier Leleu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6724.
https://doi.org/10.1182/blood-2023-186599
Published: 2023
Journal Articles

Isatuximab Plus Pomalidomide and Dexamethasone in Patients with Relapsed and/or Refractory Multiple Myeloma (RRMM) in Real-Life Context in France: IMAGE Subgroup Analysis Based on Prior Lines of Therapy and Refractory Status in Anti-CD38-Naïve Population

Xavier Leleu, Jean Fontan, Aurore Perrot, Lionel Karlin, Cyrille Touzeau, Samantha Schulmann, Salomon Manier, Karim Belhadj Merzoug, Adrien Trebouet, Patricia Zunic, Jean Marc Schiano De Colella, Christina Tekle, Marianne Gaucher, Olivier Decaux
Journal: Blood
Blood (2023) 142 (Supplement 1): 7419.
https://doi.org/10.1182/blood-2023-179532
Published: 2023
Journal Articles

Efficacy and Safety of Daratumumab Monotherapy in Newly Diagnosed Patients with Stage 3B Light-Chain Amyloidosis: A Phase 2 Study By the European Myeloma Network

Efstathios Kastritis, Monique C Minnema, Meletios A. Dimopoulos, Giampaolo Merlini, Foteini Theodorakakou, Despina Fotiou, Antoine Huart, Karim Belhadj Merzoug, Elena Papachristou, Kyriaki Manousou, Pieter Sonneveld, Giovanni Palladini
Journal: Blood
Blood (2023) 142 (Supplement 1): 539.
https://doi.org/10.1182/blood-2023-185811
Published: 2023
Journal Articles

Real-World Outcomes of Newly Diagnosed Multiple Myeloma (NDMM) Patients Treated before the Anti-CD38 Antibodies Era in France, the Emmy Cohort 2017 to 2020

Laure Vincent, Olivier Decaux, Aurore Perrot, Bruno Royer, Thomas Chalopin, Arthur Bobin, Margaret Macro, Denis Caillot, Lionel Karlin, Caroline Jacquet, Cécile Sonntag, Mohamad Mohty, Laurent Frenzel, Arnaud Jaccard, Laurence Sanhes, Driss Chaoui, Nathalie Texier, Chanaz Louni, Zakaria Maarouf, Herve Avet Loiseau, Cyrille Hulin, Karim Belhadj Merzoug
Journal: Blood
Blood (2023) 142 (Supplement 1): 3355.
https://doi.org/10.1182/blood-2023-173845
Published: 2023
Journal Articles

Dose Escalation of ISB 1342, a Novel CD38xCD3 Bispecific Antibody, in Patients with Relapsed / Refractory Multiple Myeloma (RRMM)

Prashant Kapoor, Don A. Stevens, Xavier Leleu, Karim Belhadj Merzoug, Lionel Karlin, Salomon Manier, Thomas Chalopin, Cyrille Hulin, Aurore Perrot, Jésus G Berdeja, Cristiana Costa Chase, Cyrille Touzeau, Philippe Moreau, Sanjay Mohan, Alexander Lesokhin, Carol Huff, David H. Vesole, Joshua Richter, Jeffrey Matous, Eileen Wolff, Tejas Shah, Jeppe Koch-Olsen, Andrew Garton, Vinu Menon, Sunitha Gn, Mario Perro, Eugene Zhukovsky, Cyril Konto, Lida Pacaud, Mohamad Mohty
Journal: Blood
Blood (2023) 142 (Supplement 1): 3339.
https://doi.org/10.1182/blood-2023-186664
Published: 2023
Journal Articles

Biallelic deletion of 1p32 defines ultra-high-risk myeloma, but monoallelic del(1p32) remains a strong prognostic factor

CME Clinical Trials & Observations
Anaïs Schavgoulidze, Alexis Talbot, Aurore Perrot, Titouan Cazaubiel, Xavier Leleu, Salomon Manier, Laure Buisson, Sabrina Mahéo, Laura Do Souto Ferreira, Luka Pavageau, Cyrille Hulin, Jean-Pierre Marolleau, Laurent Voillat, Karim Belhadj, Marion Divoux, Borhane Slama, Sabine Brechignac, Margaret Macro, Anne-Marie Stoppa, Laurence Sanhes, Frédérique Orsini-Piocelle, Jean Fontan, Marie-Lorraine Chretien, Hélène Demarquette, Mohamad Mohty, Hervé Avet-Loiseau, Jill Corre
Journal: Blood
Blood (2023) 141 (11): 1308–1315.
https://doi.org/10.1182/blood.2022017863
Published: 2023
Includes: Supplemental data
Journal Articles

Efficacy and Safety of Daratumumab Monotherapy in Newly Diagnosed Patients with Stage 3B Light Chain Amyloidosis: A Phase 2 Study By the European Myeloma Network

Efstathios Kastritis, Monique C. Minnema, Meletios-Athanasios Dimopoulos, Giampaolo Merlini, Foteini Theodorakakou, Despina Fotiou, Antoine Huart, Karim Belhadj, Sreeja Varghese, Kyriaki Manousou, Pieter Sonneveld, Giovanni Palladini
Journal: Blood
Blood (2022) 140 (Supplement 1): 1841–1843.
https://doi.org/10.1182/blood-2022-168757
Published: 2022
Journal Articles

Outcome of Patients with Primary Mediastinal Large B-Cell Lymphoma after R-CHOP21, R-CHOP14 and R-ACVBP: A Pooled Analysis of Clinical Trials from Lysa

David Sibon, Christian Gisselbrecht, Thierry Jo Molina, Vincent Camus, Olivier Casasnovas, Christian Recher, Nicolas Ketterer, Olivier Fitoussi, Karim Belhadj, Julie Bruneau, Marie Parrens, Jean-François Emile, Josette Briere, Bettina Fabiani, Thierry Fest, Herve Ghesquieres, Franck Morschhauser, Corinne Haioun, Thierry Lamy, Olivier Hermine, Steven Le Gouill, Jean-Philippe Jais
Journal: Blood
Blood (2022) 140 (Supplement 1): 1082–1084.
https://doi.org/10.1182/blood-2022-166228
Published: 2022
Journal Articles

What Is the Benefit of Autologous Stem Cell Transplantation in Multiple Myeloma Beyond the Age of 65? Inputs from Real-World Data in the Emmy Cohort

Aurore Perrot, Olivier Decaux, Bruno Royer, Denis Caillot, Karim Belhadj Merzoug, Agathe Farge, Laurent Frenzel, Cécile Sonntag, Bohrane Slama, Emmanuelle Bourgeois-Petit, Philippe Moreau, Laurent Voillat, Odile Luycx, Lotfi Benboubker, Gian-Matteo Pica, Frederic Maloisel, Jean-Richard Eveillard, Caroline Algrin, Anna Schmitt, Ronan Garlantézec, Nathalie Texier, Raphael Germain, Marion Willaime, Cyrille Hulin
Journal: Blood
Blood (2022) 140 (Supplement 1): 4379–4381.
https://doi.org/10.1182/blood-2022-158484
Published: 2022
Journal Articles

Initial Results of Dose Escalation of ISB 1342, a Novel CD3xCD38 Bispecific Antibody, in Patients with Relapsed / Refractory Multiple Myeloma (RRMM)

Sanjay R Mohan, Cristiana Costa Chase, Jesus G Berdeja, Lionel Karlin, Karim Belhadj, Aurore Perrot, Philippe Moreau, Cyrille Touzeau, Thomas Chalopin, Alexander M Lesokhin, Carol Ann Huff, David H. Vesole, Joshua Richter, Jeffrey V. Matous, Igor Proscurshim, Eileen Wolff, Girish Gudi, Andrew Garton, Vinu Menon, Sunitha Gn, Yacine Salhi, Eric J. Feldman, Mohamad Mohty
Journal: Blood
Blood (2022) 140 (Supplement 1): 7264–7266.
https://doi.org/10.1182/blood-2022-157525
Published: 2022
Journal Articles

Bortezomib and high-dose melphalan conditioning regimen in frontline multiple myeloma: an IFM randomized phase 3 study

Clinical Trials & Observations
Murielle Roussel, Valérie Lauwers-Cances, Margaret Macro, Xavier Leleu, Bruno Royer, Cyrille Hulin, Lionel Karlin, Aurore Perrot, Cyrille Touzeau, Marie-Lorraine Chrétien, Sophie Rigaudeau, Mamoun Dib, Emmanuelle Nicolas-Virelizier, Martine Escoffre-Barbe, Karim Belhadj, Clara Mariette, Anne-Marie Stoppa, Carla Araujo, Chantal Doyen, Jean Fontan, Brigitte Kolb, Laurent Garderet, Sabine Brechignac, Jean-Valère Malfuson, Arnaud Jaccard, Pascal Lenain, Cécile Borel, Benjamin Hebraud, Omar Benbrahim, Véronique Dorvaux, Salomon Manier, Karine Augeul-Meunier, Marie-Christiane Vekemans, Edouard Randriamalala, Driss Chaoui, Jo Caers, Carine Chaleteix, Lofti Benboubker, Laure Vincent, Sylvie Glaisner, Patricia Zunic, Borhane Slama, Jean-Richard Eveillard, Catherine Humbrecht-Kraut, Véronique Morel, Philippe Mineur, Jean-Claude Eisenmann, Hélène Demarquette, Valentine Richez, Marguerite Vignon, Denis Caillot, Thierry Facon, Philippe Moreau, Anne-Laurène Colin, Pascale Olivier, Soraya Wuilleme, Hervé Avet-Loiseau, Jill Corre, Michel Attal
Journal: Blood
Blood (2022) 139 (18): 2747–2757.
https://doi.org/10.1182/blood.2021014635
Published: 2022
Includes: Supplemental data
Journal Articles

Primary plasma cell leukemias displaying t(11;14) have specific genomic, transcriptional, and clinical features

Brief Report
Titouan Cazaubiel, Xavier Leleu, Aurore Perrot, Salomon Manier, Laure Buisson, Sabrina Maheo, Laura Do Souto Ferreira, Romain Lannes, Luka Pavageau, Cyrille Hulin, Jean-Pierre Marolleau, Laurent Voillat, Karim Belhadj, Marion Divoux, Borhane Slama, Sabine Brechignac, Margaret Macro, Anne-Marie Stoppa, Laurence Sanhes, Frédérique Orsini-Piocelle, Jean Fontan, Marie-Lorraine Chretien, Hélène Demarquette, Mohamad Mohty, Anais Schavgoulidze, Herve Avet-Loiseau, Jill Corre
Journal: Blood
Blood (2022) 139 (17): 2666–2672.
https://doi.org/10.1182/blood.2021014968
Published: 2022
Includes: Supplemental data
Journal Articles

Phase II Study of the Combination of Pomalidomide with Dexamethasone As Maintenance Therapy after First Relapse Treatment with PCD Followed or Not By Autologous Stem Cell Transplant in Multiple Myeloma Patients

Laurent Garderet, Frédérique Kuhnowski, Benoit Berge, Murielle Roussel, Martine Escoffre-Barbe, Ingrid Lafon, Thierry Facon, Xavier Leleu, Lionel Karlin, Aurore Perrot, Philippe Moreau, Gerald Marit, Anne-Marie Stoppa, Bruno Royer, Carine Chaleteix, Mourad Tiab, Carla Araujo, Pascal Lenain, Margaret Macro, Eric G. Voog, Lotfi Benboubker, Olivier Thierry Allangba, Eric Jourdan, Frédérique Orsini-Piocelle, Sabine Brechignac, Jean-Richard Eveillard, Karim Belhadj, Marc Wetterwald, Brigitte Pegourie, Arnaud Jaccard, Jean Claude Eisenmann, Sylvie Glaisner, Mohamad Mohty, Cyrille Hulin, Herve Avet Loiseau, Claire Mathiot, Michel Attal
Journal: Blood
Blood (2021) 138 (Supplement 1): 2753.
https://doi.org/10.1182/blood-2021-152136
Published: 2021
Journal Articles

Efficacy and Safety of Daratumumab Monotherapy in Newly Diagnosed Patients with Stage 3B Light Chain Amyloidosis: A Phase 2 Study By the European Myeloma Network

Efstathios Kastritis, Monique C. Minnema, Meletios A. Dimopoulos, Giampaolo Merlini, Foteini Theodorakakou, Despina Fotiou, Antoine Huart, Karim Belhadj, Alexandros Leonidakis, Kyriaki Manousou, Pieter Sonneveld, Giovanni Palladini
Journal: Blood
Blood (2021) 138 (Supplement 1): 2730.
https://doi.org/10.1182/blood-2021-152540
Published: 2021
Journal Articles

Integrative Study of a High-Grade B-Cell Lymphoma Cohort of 45 Patients: A Single Institution Real Life Study

Louise Roulin, Elsa Poullot, Paul Blanc-Durand, Cyrielle Robe, Francois Lemonnier, Fabien Le Bras, Romain Gounot, Karim Belhadj, Jehan Dupuis, Mohammad Hammoud, Taoufik El Gnaoui, Sebastien Mule, Christiane Copie Bergman, Thierry Molina, Marie Helene Delfau Larue, Emmanuel Itti, Philippe Gaulard, Corinne Haioun
Journal: Blood
Blood (2021) 138 (Supplement 1): 4576.
https://doi.org/10.1182/blood-2021-152627
Published: 2021
Journal Articles

Real-Life Survival Data after Triple-Exposure to Proteasome Inhibitors (PI), Immunomodulators (IMID) and Anti-CD38 in Multiple Myeloma Patients in the Emmy Cohort

Aurore Perrot, Cyrille Hulin, Margaret Macro, Laurent Frenzel, Carla Araujo, Philippe Moreau, Bruno Royer, Karim Belhadj, Denis Caillot, Xavier Leleu, Anne Vekhoff, Samantha Schulmann, Salomon Manier, Lionel Karlin, Laure Vincent, Sophie Rigaudeau, Driss Chaoui, Ronan Garlantezec, Nathalie Texier, Marion Willaime, Catherine Boccaccio, Olivier Decaux
Journal: Blood
Blood (2021) 138 (Supplement 1): 3764.
https://doi.org/10.1182/blood-2021-149433
Published: 2021
Journal Articles

RD Vs. VRD: What Is the First-Line, Real-Life Management of Multiple Myeloma Patients Ineligible for Stem Cell Auto Transplantation in the Emmy Cohort?

Olivier Decaux, Aurore Perrot, Laurent Frenzel, Bruno Royer, Carla Araujo, Karim Belhadj, Philippe Moreau, Denis Caillot, Xavier Leleu, Agathe Farge, Anne Vekhoff, Samantha Schulmann, Jean Fontan, Frederique Orsini, Laurence Sanhes, Valentine Richez, Arnaud Jaccard, Ronan Garlantezec, Nathalie Texier, Raphael Germain, Catherine Boccaccio, Cyrille Hulin
Journal: Blood
Blood (2021) 138 (Supplement 1): 3766.
https://doi.org/10.1182/blood-2021-149480
Published: 2021
Journal Articles

Up-front carfilzomib, lenalidomide, and dexamethasone with transplant for patients with multiple myeloma: the IFM KRd final results

Clinical Trials & Observations
Murielle Roussel, Valerie Lauwers-Cances, Soraya Wuilleme, Karim Belhadj, Salomon Manier, Laurent Garderet, Martine Escoffre-Barbe, Clara Mariette, Lotfi Benboubker, Denis Caillot, Cécile Sonntag, Cyrille Touzeau, Jehan Dupuis, Philippe Moreau, Xavier Leleu, Thierry Facon, Benjamin Hébraud, Jill Corre, Michel Attal
Journal: Blood
Blood (2021) 138 (2): 113–121.
https://doi.org/10.1182/blood.2021010744
Published: 2021