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Britta Besemer
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Journal Articles

Phase 3 randomized study of teclistamab plus daratumumab versus investigator’s choice of daratumumab and dexamethasone with either pomalidomide or Bortezomib (DPd/DVd) in patients (Pts) with relapsed refractory multiple myeloma (RRMM): Results of majestec-3

Free
María-Victoria Mateos, Nizar Bahlis, Aurore Perrot, Ajay Nooka, Jin Lu, Charlotte Pawlyn, Roberto Mina, Gaston Caeiro, Alain Kentos, Vania Hungria, Donna Reece, Ting Niu, Anne Mylin, Charlotte Hansen, Raphael Teipel, Britta Besemer, Meletios Dimopoulos, Elena Zamagni, Satoshi Yoshihara, Kihyun Kim, Chang-Ki Min, Paulus Geerts, Elena Van Leeuwen-Segarceanu, Agata Tyczynska, Juan Luis Reguera, Magnus Johansson, Markus Hansson, Mehmet Turgut, Mark Grey, Surbhi Sidana, Paula Rodriguez-Otero, Joaquin Martinez-Lopez, Hamza Hashmi, Robin Carson, Rachel Kobos, Weili Sun, Kristen Lantz, Anne Seifert, Debbie Briseno-Toomey, Lisa O'Rourke, Maria Rubin, Diego Vieyra, Lijuan Kang, Luciano Costa
Journal: Blood
Blood (2025) 146 (Supplement 2): LBA-6.
https://doi.org/10.1182/blood-2025-LBA-6
Published: 2025
Journal Articles

Trial in progress: Phase II Study of (early) combination salvage therapy with venetoclax and intensified decitabine in relapsed/refractory AML (VenSwitch)

Free
Lucas Mix, Jan Christian Schroeder, Osama Ahmad, Franziska Ginsberg, Andreas Riedel, David Soekler-Sanchez, Lennart Harland, Rebecca Froehlich, Jonas Schmidt, Nicolae Anghel, Peter Martus, Wichard Vogel, Britta Besemer, Wolfgang Bethge, Claudia Lengerke
Journal: Blood
Blood (2025) 146 (Supplement 1): 8253.
https://doi.org/10.1182/blood-2025-8253
Published: 2025
Journal Articles

Peripheral residual disease activity assessment by MALDI-TOF mass spectrometry in patients with newly-diagnosed multiple myeloma in the GMMG-HD7 study

Free
Jia xiang Jin, Varun Ginde, Stefanie Huhn, Philipp Reichert, Uta Bertsch, Roland Fenk, Britta Besemer, Amelie Boquoi, Roland Schroers, Ivana von Metzler, Mathias Hänel, Christoph Mann, Lisa Leypoldt, Bernhard Heilmeier, Thorsten Peters-Regehr, Christof Scheid, Igor Wolfgang Blau, Carsten Mueller-Tidow, Steffen Luntz, Tobias A.W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Müller, Evgenii Shumilov, Wolfgang Knauf, Christian Michel, Thomas Geer, Hendrik Riesenberg, Christoph Lutz, Marc Raab, Niels Weinhold, Martin Hoffmann, Axel Benner, Peter Findeisen, Katja Weisel, Hans Salwender, Elias K. Mai, Hartmut Goldschmidt
Journal: Blood
Blood (2025) 146 (Supplement 1): 920.
https://doi.org/10.1182/blood-2025-920
Published: 2025
Journal Articles

Feasibility and efficacy of daratumumab-vcd in transplant-ineligible elderly patients with newly diagnosed multiple myeloma: First results from the multicenter GMMG-dada study

Free
Christof Scheid, Christina Thielen, Sandra Willms, Axel Benner, Kaya Miah, Mathias Hänel, Peter Staib, Britta Besemer, Yon-Dschun Ko, Martin Schmidt-Hieber, Florian Kaiser, Timon Hansen, Maika Klaiber-Hakimi, Sebastian Theurich, Swen Wessendorf, Neise Michael, Christian Schmitt, Ullrich Graeven, Manfred Hensel, Cyrus Khandanpour, Joanna Millo, Stefanie Huhn, Michael Hundemer, Niels Weinhold, Marc Raab, Hartmut Goldschmidt, Tim Richardson
Journal: Blood
Blood (2025) 146 (Supplement 1): 4050.
https://doi.org/10.1182/blood-2025-4050
Published: 2025
Journal Articles

Outcomes of multiple myeloma (MM) patients with del 17p as a sole high risk cytogenetic abnormality who underwent either single or tandem upfront autologous stem cell transplant approaches in EBMT centres between 2016 and 2022

Free
Conal Houstoun, Patrick Hayden, Dirk-Jan Eikema, Linda Koster, Sandra Sauer, Annoek Broers, Neil Rabin, Tobias Gedde-Dahl, Britta Besemer, Matthew Collin, Luisa Giaccone, Kristina Carlson, Thomas Pabst, Deborah Richardson, Jean Marc Schiano De Colella, Bertrand Arnulf, Mathias Hänel, Christine Schuermans, Francesco Zaja, Kavita Raj, Joanna Drozd-Sokolowska, Laurent Garderet, Nico Gagelmann, Meral Beksac, Donal McLornan
Journal: Blood
Blood (2025) 146 (Supplement 1): 4583.
https://doi.org/10.1182/blood-2025-4583
Published: 2025
Journal Articles

Phenotypic evolution of circulating tumor plasma cells across MGUS, SMM and multiple myeloma

Free
Martin Pietzsch, Sina Beer, Lucca Kimmich, Chiara Windsor, Britta Besemer, Claudia Lengerke, Anna Stanger
Journal: Blood
Blood (2025) 146 (Supplement 1): 3914.
https://doi.org/10.1182/blood-2025-3914
Published: 2025
Journal Articles

Health-related quality of life (HRQoL) in patients with newly diagnosed multiple myeloma (NDMM) eligible for transplantation and treated with isatuximab, lenalidomide, bortezomib, and dexamethasone (Isa-RVd) versus rvd alone: Results from part 1 of the GMMG-HD7 study

Free
Elias K. Mai, Uta Bertsch, Roland Fenk, Britta Besemer, Amelie Boquoi, Roland Schroers, Ivana von Metzler, Mathias Hänel, Christoph Mann, Lisa Leypoldt, Bernhard Heilmeier, Stefanie Huhn, Christof Scheid, Igor Wolfgang Blau, Steffen Luntz, Tobias A.W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Mueller, Evgenii Shumilov, Christian Michel, Thomas Geer, Hendrik Riesenberg, Christoph Lutz, Marc Raab, Martin Hoffmann, Erin Comerford, Maeva Kyheng, Feng Lin, Stephanie Rhoten, Tatiana Lavrova, Hans Salwender, Katja Weisel, Hartmut Goldschmidt
Journal: Blood
Blood (2025) 146 (Supplement 1): 2263.
https://doi.org/10.1182/blood-2025-2263
Published: 2025
Journal Articles

Trial in progress: Safety and feasibility of a venetoclax-augmented treosulfan-based reduced intensity conditioning before allogeneic stem cell transplantation in AML, MDS/AML and higher risk MDS (VeStAL)

Free
Lucas Mix, Wichard Vogel, Britta Besemer, Peter Martus, Claudia Lengerke, Wolfgang Bethge, Christoph Faul
Journal: Blood
Blood (2025) 146 (Supplement 1): 6001.
https://doi.org/10.1182/blood-2025-6001
Published: 2025
Journal Articles

Remission conversion drives outcomes after CAR T-cell therapy for multiple myeloma: a registry analysis from the DRST

Available to Purchase
Clinical Trials & Observations
Maximilian Merz, Nico Gagelmann, Samih Smaili, Sarah Flossdorf, Sandra Sauer, Christof Scheid, Bastian von Tresckow, Gerald Wulf, Katja Weisel, Igor Wolfgang Blau, Monika Engelhardt, Ralph Wäsch, Natalie Schub, Raphael Teipel, Judith Hecker, Johannes Waldschmidt, Britta Besemer, Ben-Niklas Baermann, Simon Call, Leo Hansmann, Francis Ayuketang Ayuk, Marc S. Raab, Hermann Einsele, Uwe Platzbecker, Nicolaus Kröger
Journal: Blood
Blood (2025) 146 (14): 1677–1686.
https://doi.org/10.1182/blood.2025028330
Published: 2025
Includes: Supplemental data
Journal Articles

Salvage autologous transplant in relapsed multiple myeloma: long-term follow-up of the phase 3 GMMG ReLApsE trial

Open Access
Clinical Trials & Observations Brief Report
Marc-Andrea Baertsch, Jana Schlenzka, Thomas Hielscher, Marc S. Raab, Sandra Sauer, Maximilian Merz, Elias Karl Mai, Carsten Müller-Tidow, Steffen Luntz, Anna Jauch, Peter Brossart, Martin Goerner, Stefan Klein, Bertram Glass, Peter Reimer, Ullrich Graeven, Roland Fenk, Mathias Haenel, Ivana von Metzler, Hans W. Lindemann, Christof Scheid, Igor-Wolfgang Blau, Hans J. Salwender, Richard Noppeney, Britta Besemer, Katja C. Weisel, Hartmut Goldschmidt
Journal: Blood
Blood (2025) 145 (16): 1780–1787.
https://doi.org/10.1182/blood.2024027342
Published: 2025
Includes: Supplemental data
Journal Articles

Efficacy and safety of teclistamab in patients with relapsed/refractory multiple myeloma after BCMA-targeting therapies

Free
Clinical Trials & Observations
Cyrille Touzeau, Amrita Y. Krishnan, Philippe Moreau, Aurore Perrot, Saad Z. Usmani, Salomon Manier, Michele Cavo, Carmen Martinez Chamorro, Ajay K. Nooka, Thomas G. Martin, Lionel Karlin, Xavier Leleu, Nizar J. Bahlis, Britta Besemer, Lixia Pei, Sarah Stein, Shun Xin Wang Lin, Danielle Trancucci, Raluca I. Verona, Suzette Girgis, Xin Miao, Clarissa M. Uhlar, Katherine Chastain, Alfred L. Garfall
Journal: Blood
Blood (2024) 144 (23): 2375–2388.
https://doi.org/10.1182/blood.2023023616
Published: 2024
Includes: Supplemental data
Journal Articles

Health-Related Quality of Life (HRQoL) in Patients with Newly Diagnosed Multiple Myeloma (NDMM) Ineligible for Transplantation and Treated with Isatuximab, Bortezomib, Lenalidomide, and Dexamethasone (Isa-VRd) Vs. Vrd Alone: Results from the Imroz Study

Free
Meletios Dimopoulos, Thierry Facon, Meral Beksac, Ludek Pour, Roman Hajek, Zhuogang Liu, Jiri Minarik, Philippe Moreau, Joanna Romejko-Jarosinska, Ivan Špička, Vladimir I. Vorobyev, Britta Besemer, Tadao Ishida, Wojciech Janowski, Sevgi Kalayoglu Besisik, Gurdeep Parmar, Pawel Robak, Elena Zamagni, Hartmut Goldschmidt, Thomas Martin, Salomon Manier, Mohamad Mohty, Robert Z. Orlowski, Erin Comerford, Claire Tian, Jérôme Msihid, Feng Lin, Stephanie Rhoten, Xavier. P Leleu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3352.
https://doi.org/10.1182/blood-2024-207087
Published: 2024
Journal Articles

Impact of Clonal Heterogeneity in Newly Diagnosed, Transplant-Eligible Multiple Myeloma - Subgroup Analysis of the GMMG HD6 Phase III Trial

Free
Maximilian Merz, Ema Pozek, Kaya Miah, Uta Bertsch, Britta Besemer, Mathias Hänel, Julia Krzykalla, Roland Fenk, Jana Schlenzka, Markus Munder, Christine Hanoun, Christoph Mann, Niels Weinhold, Christof Scheid, Roland Schroers, Igor Wolfgang Blau, Stefanie Huhn, Dirk Hose, Anna Jauch, Christina Kunz, Ivana von Metzler, Aneta Schieferdecker, Jörg Thomalla, Peter Reimer, Rolf Mahlberg, Ullrich Graeven, Stephan Kremers, Uwe Martens, Manfred Hensel, Axel Benner, Andrea Seidel-Glätzer, Katja C. Weisel, Marc S. Raab, Hans Salwender, Hartmut Goldschmidt, Elias K. Mai
Journal: Blood
Blood (2024) 144 (Supplement 1): 84.
https://doi.org/10.1182/blood-2024-201972
Published: 2024
Journal Articles

Single Vs. Tandem Autologous Stem Cell Transplantation in Newly Diagnosed Multiple Myeloma: A Real-World Multi-Center Study from the German Registry for Hematopoietic Stem Cell Transplantation and Cell Therapy (DRST)

Free
Nora Grieb, Alexander Oeser, Maximilian Ferle, Franziska Hanke, Sarah Flossdorf, Sandra Sauer, Hartmut Goldschmidt, Carsten Müller-Tidow, Hans Salwender, Roland Fenk, Monika Engelhardt, Robert Zeiser, Vladan Vucinic, Georg-Nikolaus Franke, Igor Wolfgang Blau, Daniel Teschner, Hermann Einsele, Christoph Richard Kimmich, Miriam Kull, Britta Besemer, Nico Gagelmann, Nicolaus Kröger, Thomas Neumuth, Uwe Platzbecker, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 708.
https://doi.org/10.1182/blood-2024-198638
Published: 2024
Journal Articles

Quality of Life in the Multicenter, Randomized, Phase 3 GMMG-HD6 Trial Applying Elotuzumab, Lenalidomide, Bortezomib and Dexaemethason in Patients with Newly-Diagnosed Multiple Myeloma

Free
Anna Fleischer, Elias K. Mai, Kaya Miah, Uta Bertsch, Britta Besemer, Mathias Hänel, Roland Fenk, Markus Munder, Christine Hanoun, Igor Wolfgang Blau, Christoph Mann, Christof Scheid, Roland Schroers, Ivana von Metzler, Aneta Schieferdecker, Jörg Thomalla, Peter Reimer, Rolf Mahlberg, Ullrich Graeven, Stephan Kremers, Uwe Martens, Christian Kunz, Manfred Hensel, Marc S. Raab, Katja C. Weisel, Hans Salwender, Imad Maatouk, Hartmut Goldschmidt
Journal: Blood
Blood (2024) 144 (Supplement 1): 1963.
https://doi.org/10.1182/blood-2024-205230
Published: 2024
Journal Articles

Long-Term Follow-up Analysis of Progression-Free and Overall Survival in Newly Diagnosed Multiple Myeloma Patients from the GMMG Myeloma Registry Following the Randomized Phase III GMMG-HD6 Trial

Free
Anne-Valérie Keller, Marina Hajiyianni, Eileen Kurre, Elias Karl Mai, Uta Bertsch, Axel Benner, Steffen Luntz, Marc-Steffen Raab, Britta Besemer, Christian Sebastian Michel, Roland Schroers, Roland Fenk, Hans Salwender, Igor Wolfgang Blau, Mathias Hänel, Christoph Mann, Hartmut Goldschmidt
Journal: Blood
Blood (2024) 144 (Supplement 1): 5140.
https://doi.org/10.1182/blood-2024-194188
Published: 2024
Journal Articles

Isatuximab, Bortezomib, Lenalidomide, and Dexamethasone (Isa-VRd) in Patients with Newly Diagnosed Multiple Myeloma (NDMM): Analyses of Minimal Residual Disease (MRD) Negativity Dynamics in the Phase 3 Imroz Study

Free
Robert Z. Orlowski, Meletios-Athanasios Dimopoulos, Xavier Leleu, Zhuogang Liu, Tadao Ishida, Roman Hajek, Ivan Špička, Joanna Romejko-Jarosinska, Vladimir I. Vorobyev, Britta Besemer, Sevgi Beşışık, Pawel Robak, Hartmut Goldschmidt, Thomas Martin, Mohamad Mohty, Sandrine Macé, Ercem Kodas, Christina Tekle, Andrea Shafer, Philippe Moreau
Journal: Blood
Blood (2024) 144 (Supplement 1): 770.
https://doi.org/10.1182/blood-2024-203818
Published: 2024
Journal Articles

Isatuximab, Lenalidomide, Bortezomib and Dexamethasone Induction Therapy for Transplant-Eligible Patients with Newly Diagnosed Multiple Myeloma: Final Progression-Free Survival Analysis of Part 1 of an Open-Label, Multicenter, Randomized, Phase 3 Trial (GMMG-HD7)

Free
Hartmut Goldschmidt, Uta Bertsch, Ema Pozek, Axel Benner, Roland Fenk, Britta Besemer, Christine Hanoun, Roland Schroers, Ivana von Metzler, Mathias Hänel, Christoph Mann, Lisa Leypoldt, Bernhard Heilmeier, Stefanie Huhn, Sabine Vogel, Michael Hundemer, Christof Scheid, Igor Wolfgang Blau, Steffen Luntz, Tobias A.W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Mueller, Evgenii Shumilov, Wolfgang Knauf, Christian Sebastian Michel, Thomas Geer, Hendrik Riesenberg, Christoph Lutz, Marc-Steffen Raab, Martin Hoffmann, Katja C. Weisel, Hans Salwender, Elias K. Mai
Journal: Blood
Blood (2024) 144 (Supplement 1): 769.
https://doi.org/10.1182/blood-2024-193308
Published: 2024
Journal Articles

Impact of Minimal Residual Disease on Progression-Free Survival in Patients with Newly Diagnosed Multiple Myeloma Treated with Isatuximab, Lenalidomide, Bortezomib and Dexamethasone Induction Therapy in the Phase 3 GMMG-HD7 Trial

Free
Elias K. Mai, Hans Salwender, Michael Hundemer, Uta Bertsch, Ema Pozek, Axel Benner, Roland Fenk, Britta Besemer, Christine Hanoun, Roland Schroers, Ivana von Metzler, Mathias Hänel, Christoph Mann, Lisa Leypoldt, Bernhard Heilmeier, Stefanie Huhn, Sabine Vogel, Christof Scheid, Igor Wolfgang Blau, Steffen Luntz, Niels Weinhold, Tobias A.W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Mueller, Evgenii Shumilov, Wolfgang Knauf, Christian Sebastian Michel, Thomas Geer, Hendrik Riesenberg, Christoph Lutz, Marc S. Raab, Martin Hoffmann, Katja C. Weisel, Hartmut Goldschmidt
Journal: Blood
Blood (2024) 144 (Supplement 1): 364.
https://doi.org/10.1182/blood-2024-194768
Published: 2024
Journal Articles

Alnuctamab (ALNUC; BMS-986349; CC-93269), a 2+1 B-Cell Maturation Antigen (BCMA) × CD3 T-Cell Engager (TCE), Administered Subcutaneously (SC) in Patients (Pts) with Relapsed/Refractory Multiple Myeloma (RRMM): Updated Results from a Phase 1 First-in-Human Clinical Study

Free
Noffar Bar, Maria Victoria Mateos, Paz Ribas, Markus Hansson, Laura Paris, Craig C. Hofmeister, Paula Rodriguez Otero, Maria Aranzazu Bermúdez, Thomas Martin, Armando Santoro, Andrew J. Yee, Maria Creignou, Cristina Encinas Rodriguez, Claudio Cerchione, Javier De La Rubia, Albert Oriol, Heidi Waibel, Britta Besemer, Ethan Thompson, Brian Kiesel, Jinjie Chen, Alexander Chung, Isaac W. Boss, Allison Gaudy, Shaoyi Li, Kevin Hsu, Colin Godwin, Michael R. Burgess, Jesús San-Miguel, Luciano Costa
Journal: Blood
Blood (2023) 142 (Supplement 1): 2011.
https://doi.org/10.1182/blood-2023-180013
Published: 2023