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Journal Articles

Immunological Subgroups Predicting Efficacy of Elotuzumab in Multiple Myeloma Patients: Insights from the GMMG-HD6 Clinical Trial

Gigi Nu Hoang Quy Ton, Katharina Kriegsmann, Mohamed H.S. Awwad, Axel Benner, Uta Bertsch, Britta Besemer, Mathias Hänel, Roland Fenk, Jana Schlenzka, Markus Munder, Jan Dürig, Igor Wolfgang Blau, Stefanie Huhn, Dirk Hose, Anna Jauch, Andreas Neubauer, Niels Weinhold, Christof Scheid, Roland Schroers, Ivana von Metzler, Aneta Schieferdecker, Jörg Thomalla, Peter Reimer, Rolf Mahlberg, Ullrich Graeven, Stephan Kremers, Uwe Martens, Christian Kunz, Manfred Hensel, Andrea Seidel-Glätzer, Katja Weisel, Hans Salwender, Carsten Müller-Tidow, Marc S. Raab, Hartmut Goldschmidt, Elias K. Mai, Michael Hundemer
Journal: Blood
Blood (2023) 142 (Supplement 1): 1991.
https://doi.org/10.1182/blood-2023-189169
Published: 2023
Journal Articles

Implications and Prognostic Impact of Mass Spectrometry in Patients with Newly-Diagnosed Multiple Myeloma

Elias K Mai, Stefanie Huhn, Kaya Miah, Alexandra M Poos, Christof Scheid, Katja Weisel, Uta Bertsch, Markus Munder, Oscar Berlanga, Dirk Hose, Anja Seckinger, Anna Jauch, Igor Wolfgang Blau, Mathias Haenel, Hans Salwender, Axel Benner, Marc S Raab, Hartmut Goldschmidt, Niels Weinhold
Journal: Blood
Blood (2022) 140 (Supplement 1): 2341–2343.
https://doi.org/10.1182/blood-2022-156169
Published: 2022
Journal Articles

Bone Marrow Immune Signatures in Multiple Myeloma Are Linked to Tumor Heterogeneity and Treatment Outcome

Simon Steiger, Raphael Lutz, Nina Prokoph, Subarna Palit, Stephan M Tirier, Philipp Reichert, Anja Baumann, Nadine Hefner, Sabrina Schumacher, Dominik Vonficht, Florian Grünschläger, Alexandra M Poos, Lukas John, Laleh Haghverdi, Jan-Philipp Mallm, Elias K Mai, Mirco Friedrich, Katharina Kriegsmann, Mohamed H.S. Awwad, Anna Jauch, Uta Bertsch, Diana Tichy, Carsten Müller-Tidow, Roland Schroers, Hans Salwender, Britta Besemer, Roland Fenk, Katja Weisel, Hartmut Goldschmidt, Stefanie Huhn, Michael Hundemer, Karsten Rippe, Simon Haas, Niels Weinhold, Marc S Raab
Journal: Blood
Blood (2022) 140 (Supplement 1): 2083–2085.
https://doi.org/10.1182/blood-2022-168685
Published: 2022
Journal Articles

Prediction of Early Death and Severe Infections during Novel Agent-Based Induction Therapy in Newly-Diagnosed Multiple Myeloma: An Intergroup Analysis from the German Speaking Myeloma Multicenter Group, the Dutch-Belgian Cooperative Trial Group for Hematology Oncology Foundation and the European Myeloma Network

Elias K Mai, Thomas Hielscher, Uta Bertsch, Hans Salwender, Sonja Zweegman, Markus Munder, Lucia Pantani, Peter Brossart, Meral Beksac, Igor Wolfgang Blau, Marc-Steffen Raab, Jan Dürig, Nicola Giesen, Britta Besemer, Roland Fenk, Peter Reimer, Bronno van der Holt, Mathias Haenel, Ivana v. Metzler, Ullrich Graeven, Mario Boccadoro, Christof Scheid, Meletios A. Dimopoulos, Katja Weisel, Michele Cavo, Pieter Sonneveld, Hartmut Goldschmidt
Journal: Blood
Blood (2021) 138 (Supplement 1): 3792.
https://doi.org/10.1182/blood-2021-145289
Published: 2021
Journal Articles

Elotuzumab in Combination with Lenalidomide, Bortezomib, Dexamethasone and Autologous Transplantation for Newly-Diagnosed Multiple Myeloma: Results from the Randomized Phase III GMMG-HD6 Trial

Hartmut Goldschmidt, Elias K Mai, Uta Bertsch, Britta Besemer, Mathias Haenel, Kaya Miah, Roland Fenk, Jana Schlenzka, Markus Munder, Jan Dürig, Igor Wolfgang Blau, Stefanie Huhn, Dirk Hose, Anna Jauch, Christina Kunz, Andreas Neubauer, Christof Scheid, Roland Schroers, Ivana v. Metzler, Aneta Schieferdecker, Joerg Thomalla, Peter Reimer, Rolf Mahlberg, Ullrich Graeven, Stephan Kremers, Uwe M. Martens, Christian Kunz, Manfred Hensel, Andrea Seidel-Glaetzer, Katja Weisel, Marc-Steffen Raab, Hans Salwender
Journal: Blood
Blood (2021) 138 (Supplement 1): 486.
https://doi.org/10.1182/blood-2021-147323
Published: 2021
Journal Articles

Addition of Isatuximab to Lenalidomide, Bortezomib and Dexamethasone As Induction Therapy for Newly-Diagnosed, Transplant-Eligible Multiple Myeloma Patients: The Phase III GMMG-HD7 Trial

Hartmut Goldschmidt, Elias K Mai, Eva Nievergall, Roland Fenk, Uta Bertsch, Diana Tichy, Britta Besemer, Jan Dürig, Roland Schroers, Ivana v. Metzler, Mathias Haenel, Christoph Mann, Anne-Marie Asemissen, Bernhard Heilmeier, Stefanie Huhn, Katharina Kriegsmann, Niels Weinhold, Steffen P. Luntz, Tobias A. W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Mueller, Cyrus Khandanpour, Wolfgang Knauf, Markus Munder, Thomas Geer, Hendrik Riesenberg, Joerg Thomalla, Martin Hoffmann, Marc-Steffen Raab, Hans Salwender, Katja Weisel
Journal: Blood
Blood (2021) 138 (Supplement 1): 463.
https://doi.org/10.1182/blood-2021-145097
Published: 2021
Journal Articles

A New Risk Stratification Model (R2-ISS) in Newly Diagnosed Multiple Myeloma: Analysis of Mature Data from 7077 Patients Collected By European Myeloma Network within Harmony Big Data Platform

Mattia D'Agostino, MD, Juan-José Lahuerta, MD PhD, Ruth Wester, MD, Anders Waage, MD PhD, Uta Bertsch, Elena Zamagni, Maria-Victoria Mateos, MD PhD, Alessandra Larocca, Daniele Dall'Olio, Niels W. C. J. van de Donk, David Cairns, MSc, PhD, Serena Rocchi, Hans Salwender, MD, Joan Blade Creixenti, Bronno van der Holt, PhD, Castellani Gastone, Giovannino Ciccone, Andrea Capra, Jan Dürig, MD, Sara Bringhen, MD, Sonja Zweegman, MDPhD, Michele Cavo, Hartmut Goldschmidt, MD, Gordon Cook, MB ChB, PhD, Jesus Maria Hernández-Rivas, MD PhD, Jesus F. San-Miguel, MD PhD, Mario Boccadoro, Pieter Sonneveld, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34–37.
https://doi.org/10.1182/blood-2020-137021
Published: 2020
Journal Articles

Validation and Improvement Opportunities of the Revised International Staging System for Multiple Myeloma: An Analysis on Mature Data from European Clinical Trials within the Harmony Big Data Platform

Mattia D'Agostino, MD, Anders Waage, MD PhD, Juan-José Lahuerta, MD PhD, Uta Bertsch, Elena Zamagni, MD, Lars Bullinger, Alessandra Larocca, Maria-Victoria Mateos, Niels W. C. J. Van De Donk, Hans Jürgen Salwender, MD, Joan Bladé, MD, Bronno van der Holt, PhD, Paola Tacchetti, Giovannino Ciccone, Sonja Zweegman, Hartmut Goldschmidt, Michele Cavo, Jesús San-Miguel, Pieter Sonneveld, Mario Boccadoro, Jesús María Hernández-Rivas, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1773.
https://doi.org/10.1182/blood-2019-124321
Published: 2019
Journal Articles

MCT1 As Molecularly Validated Predictive Marker for Lenalidomide-Maintenance Therapy in Multiple Myeloma

Jacob Stroh, Anja Seckinger, Michael Heider, Ruth Eichner, Martina Emde, Hans Salwender, Uta Bertsch, Hartmut Goldschmidt, MD, Katja Weisel, Christof Scheid, MD, Dirk Hose, MD, Florian Bassermann, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3187.
https://doi.org/10.1182/blood-2019-130734
Published: 2019
Journal Articles

Bortezomib-Based Induction and Maintenance Overcomes the Negative Prognostic Impact of Renal Impairment and del17p in Transplant-Eligible Myeloma Patients: Long Term Results from the Phase III HOVON-65/GMMG-HD4 Study after Median 137 Months Follow up

Christof Scheid, MD, Henk Lokhorst, MD PhD, Igor W Blau, MD PhD, Bronno Van Der Holt, PhD, Uta Bertsch, Sonja Zweegman, MD PhD, Katja Weisel, Edo Vellenga, Marie José Kersten, MD PhD, Sandra Croockewit, Elias K Mai, MD, Reinier Raymakers, MD PhD, Dirk Hose, MD, Anna Jauch, Jens Hillengass, MD, Marian Stevens-Kroef, PhD, Marc S Raab, MD PhD, Kai Neben, Stephan Stilgenbauer, Annemiek Broyl, MD PhD, Hans-Walter Lindemann, MD, Gerard Bos, MD PhD, Peter Brossart, MD, Marinus van Marwijk Kooij, MD PhD, Paula F Ypma, MD PhD, Ulrich Dührsen, Prof, MD PhD, Ron Schaafsma, MD PhD, Thomas Hielscher, Hans Salwender, Hartmut Goldschmidt, MD, Pieter Sonneveld
Journal: Blood
Blood (2019) 134 (Supplement_1): 3308.
https://doi.org/10.1182/blood-2019-129684
Published: 2019
Journal Articles

Quantitative Integrative Prediction of Survival Probability in Multiple Myeloma Using Molecular and Clinical Prognostic Factors in 657 Patients Treated with Bortezomib-Based Induction, High-Dose Therapy and Autologous Stem Cell Transplantation

Manuela Hummel, Thomas Hielscher, Hans Jürgen Salwender, MD, Christof Scheid, Hans Martin, MD, Uta Bertsch, MD, Hartmut Goldschmidt, MD, Anja Seckinger, Dirk Hose, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 403.
https://doi.org/10.1182/blood-2018-99-113307
Published: 2018
Journal Articles

Treatment Response and Long-Term Survival in Multiple Myeloma in the GMMG-HD4 Trial - Neither Profit All Molecular Entities Alike, Nor Are Remissions to Different Regimen Equal

Anja Seckinger, Hans Jürgen Salwender, MD, Hans Martin, MD, Christof Scheid, Thomas Hielscher, Uta Bertsch, MD, Manuela Hummel, Anna Jauch, PhD, Wolfgang Knauf, Martina Emde, Susanne Beck, Kai Neben, Henk M. Lokhorst, MD PhD, Bronno van der Holt, PhD, Ulrich Duehrsen, MD, Jan Dürig, Hans-Walter Lindemann, MD, Ingo Schmidt-Wolf, Mathias Haenel, MD, Bernd Lathan, Marc S Raab, MD PhD, Carsten Müller-Tidow, MD, Pieter Sonneveld, MD PhD, Igor Wolfgang Blau, Jens Hillengass, MD, Katja Weisel, MD, Hartmut Goldschmidt, MD, Dirk Hose, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4485.
https://doi.org/10.1182/blood-2018-99-113284
Published: 2018
Journal Articles

Circulating Tumor Cells As a Surrogate Marker for Bone Marrow Minimal Residual Disease and an Adverse Prognostic Factor for Patients with Multiple Myelom

Stefanie Huhn, PhD, Mathias Hänel, MD, Thomas Hielscher, PhD, Uta Bertsch, MD, Hans Jürgen Salwender, Norma Peter, MD, Hartmut Kirchner, Helga Bernhard, MD, Martin Vogel, Ralf Angermund, Martin Goerner, MD, Katja C. Weisel, Jan Duering, Igor W Blau, Niels Weinhold, PhD, Hartmut Goldschmidt, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4359.
https://doi.org/10.1182/blood.V130.Suppl_1.4359.4359
Published: 2017
Journal Articles

A Predictive Score for Early Mortality during Induction Therapy in Newly Diagnosed Transplant-Eligible Multiple Myeloma - an Analysis from Five GMMG and HOVON Multicenter Phase III Trials

Elias K Mai, MD, Thomas Hielscher, PhD, Uta Bertsch, MD, Jana Schlenzka, MD, Hans Jürgen Salwender, Henk M Lokhorst, Markus Munder, MD, Bronno van der Holt, Christian Gerecke, MD, Michael Pfreundschuh, MD, Ulrich Duhrsen, Peter Brossart, MD, Sonja Zweegman, MD PhD, Kai Neben, Jens Hillengass, MD, Marc-Steffen S Raab, Dirk Hose, MD, Edo Vellenga, MD, Maximilian Merz, MD, Iris Breitkreutz, MD, Anna Jauch, Marie José Kersten, MD, Hans Martin, Hans-Walter Lindemann, Norma Peter, MD, Sandra Croockewit, MD, Igor Wolfgang Blau, MD, Christof Scheid, MD, Katja C. Weisel, Pieter Sonneveld, MDPhD, Hartmut Goldschmidt, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2016.
https://doi.org/10.1182/blood.V130.Suppl_1.2016.2016
Published: 2017
Journal Articles

Response-Adapted Lenalidomide Maintenance in Newly Diagnosed, Transplant-Eligible Multiple Myeloma: Results from the Multicenter Phase III GMMG-MM5 Trial

Hartmut Goldschmidt, MD, Elias K Mai, MD, Jan Dürig, MD, Christof Scheid, MD, Katja C. Weisel, Christina Kunz, Uta Bertsch, MD, Thomas Hielscher, PhD, Markus Munder, MD, Hans-Walter Lindemann, Barbara Huegle-Doerr, Dirk Hose, MD, Anja Seckinger, Stefanie Huhn, PhD, Anna Jauch, Bernhard Rabold, Ahmet Elmaagacli, MD, Christian Gerecke, MD, Peter Brossart, MD, Martin Goerner, MD, Helga Bernhard, MD, Martin Hoffmann, MD, Jens Hillengass, MD, Marc-Steffen S Raab, Igor Wolfgang Blau, MD, Mathias Hänel, MD, Hans Jürgen Salwender
Journal: Blood
Blood (2017) 130 (Supplement 1): 400.
https://doi.org/10.1182/blood.V130.Suppl_1.400.400
Published: 2017
Journal Articles

Direct Assessment of IgA and IgG Paraprotein By Hevylite Assay and Correlation to IMWG Response and Progression-Free Survival in Newly Diagnosed, Transplant-Eligible Multiple Myeloma Patients in the Prospective Phase III GMMG-MM5 Trial

Christof Scheid, MD, Anja Seckinger, Jan Dürig, MD, Katja C. Weisel, Christina Kunz, Uta Bertsch, MD, Thomas Hielscher, PhD, Markus Munder, MD, Hans-Walter Lindemann, Barbara Huegle-Doerr, Stefanie Huhn, PhD, Elias K Mai, MD, Anna Jauch, Bernhard Rabold, Christian Gerecke, MD, Peter Brossart, MD, Martin Goerner, MD, Helga Bernhard, MD, Martin Hoffmann, MD, Jens Hillengass, MD, Marc-Steffen S Raab, Igor Wolfgang Blau, MD, Mathias Haenel, Dirk Hose, MD, Hartmut Goldschmidt, MD, Hans Jürgen Salwender
Journal: Blood
Blood (2017) 130 (Supplement 1): 1784.
https://doi.org/10.1182/blood.V130.Suppl_1.1784.1784
Published: 2017
Journal Articles

The Prognostic and Predictive Value of IKZF1 and IKZF3 Expression in T-Cells in Patients with Multiple Myeloma

Mohamed H.S. Awwad, Katharina Kriegsmann, MD MBA, Julian Plaumann, Michael Benn, Jens Hillengass, MD, Marc-Steffen S Raab, Uta Bertsch, MD, Markus Munder, MD, Katja C. Weisel, Hans Jürgen Salwender, Mathias Hänel, MD, Roland Fenk, MD, Jan Dürig, MD, Carsten Müller-Tidow, Hartmut Goldschmidt, MD, Michael Hundemer
Journal: Blood
Blood (2017) 130 (Supplement 1): 1846.
https://doi.org/10.1182/blood.V130.Suppl_1.1846.1846
Published: 2017
Journal Articles

Evaluation of Stem Cell Mobilization in Patients with Multiple Myeloma after Lenalidomide-Based Induction Chemotherapy within the GMMG-HD6 Trial

Patrick Wuchter, MD, Uta Bertsch, MD, Hans-Juergen Salwender, MD, Markus Munder, MD, Mathias Haenel, MD, Axel Benner, Natalia Becker, PhD, Roland Fenk, MD, Jan Duerig, MD, Igor Wolfgang Blau, MD, Katharina Lisenko, MD, Jens Hillengass, MD, Marc S. Raab, MD, Marc Andrea Baertsch, MD, Andrea Seidel-Glaetzer, Anthony D Ho, MD, Ullrich Graeven, MD, Christof Scheid, MD, Katja Weisel, MD, Hartmut Goldschmidt, MD
Journal: Blood
Blood (2016) 128 (22): 3373.
https://doi.org/10.1182/blood.V128.22.3373.3373
Published: 2016
Journal Articles

Longitudinal Fluorescence in Situ Hybridization at Primary Diagnosis and Relapse Reveals Clonal Evolution after Autologous Stem Cell Transplantation in Multiple Myeloma

Maximilian Merz, MD, Thomas Hielscher, Anja Seckinger, MD, Dirk Hose, MD, Uta Bertsch, MD, Kai Neben, MD, Marc S Raab, MD, Igor Blau, Hans Walter Lindemann, MD, Ingo GH Schmidt-Wolf, MD, Christof Scheid, MD PhD, Mathias Haenel, MD, Katja Weisel, MD, Hartmut Goldschmidt, MD, Anna Jauch, PhD, Jens Hillengass, MD
Journal: Blood
Blood (2016) 128 (22): 4415.
https://doi.org/10.1182/blood.V128.22.4415.4415
Published: 2016
Journal Articles

Profound Impact of Sample Processing Delay on Gene Expression of Multiple Myeloma Plasma Cells

Tobias Meissner, Anja Seckinger, MD, Kari Hemminki, PhD, Uta Bertsch, MD, Asta Foersti, Mathias Haenel, MD, Jan Duering, Hans-Juergen Salwender, MD, Hartmut Goldschmidt, MD, Gareth J Morgan, MDPhD, Dirk Hose, MD, Niels Weinhold, PhD
Journal: Blood
Blood (2015) 126 (23): 2996.
https://doi.org/10.1182/blood.V126.23.2996.2996
Published: 2015