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Journal Articles

Clinical Implications of p53 Dysfunction in Patients with Myelodysplastic Syndromes

Elena Riva, Matteo Zampini, Termanini Alberto, Lorenzo Dall'Olio, Alessandra Merlotti, Austin Kulasekararaj, Michela Calvi, Clara Di Vito, Daoud Rahal, Arturo Bonometti, Giorgio Croci, Emanuela Boveri, Umberto Gianelli, Maurilio Ponzoni, Antonio Russo, Benedetta Tinterri, Francesca Re, Elisabetta Sauta, Elena Saba, Erica Travaglino, Marta Ubezio, Alessia Campagna, Luca Lanino, Giulia Maggioni, Cristina Astrid Tentori, Chiara Milanesi, Nicla Manes, Saverio D'Amico, Francesca Ficara, Laura Crisafulli, Domenico Mavilio, Enrico Lugli, Armando Santoro, Maria Diez-Campelo, Guillermo Sanz, Francesc Solé, Uwe Platzbecker, Valeria Santini, Shahram Kordasti, Pierre Fenaux, Torsten Haferlach, Daniel Remondini, Castellani Gastone, Matteo G. Della Porta
Journal: Blood
Blood (2022) 140 (Supplement 1): 4001–4004.
https://doi.org/10.1182/blood-2022-166050
Published: 2022
Journal Articles

Real-World Validation of Molecular International Prognostic Scoring System (IPSS-M) for Myelodysplastic Syndromes

Elisabetta Sauta, Marie Robin, Matteo Bersanelli, Erica Travaglino, Manja Meggendorfer, Lin-Pierre Zhao, Juan Carlos Caballero Berrocal, Giulia Maggioni, Cristina Astrid Tentori, Massimo Bernardi, Carmen Di Grazia, Luca Vago, Giulia Rivoli, Lorenza Borin, Saverio D'Amico, Marta Ubezio, Alessia Campagna, Antonio Russo, Daniele Mannina, Luca Lanino, Patrizia Chiusolo, Luisa Giaccone, Maria Teresa Voso, Marta Riva, Esther Natalie Oliva, Matteo Zampini, Elena Riva, Olivier Nibourel, Claudia Sala, Marilena Bicchieri, Niccolò Bolli, Alessandro Rambaldi, Francesco Passamonti, Victor Savevski, Armando Santoro, Ulrich Germing, Shahram Kordasti, Valeria Santini, Maria Diez-Campelo, Guillermo Sanz, Francesc Solé, Wolfgang Kern, Uwe Platzbecker, Lionel Ades, Pierre Fenaux, Torsten Haferlach, Castellani Gastone, Matteo G. Della Porta
Journal: Blood
Blood (2022) 140 (Supplement 1): 1121–1124.
https://doi.org/10.1182/blood-2022-163634
Published: 2022
Journal Articles

Machine Learning Allows the Identification of New Co-Mutational Patterns with Prognostic Implications in NPM1 Mutated AML - Results of the European Harmony Alliance

Alberto Hernández Sánchez, Angela Villaverde Ramiro, Eric Sträng, Castellani Gastone, Caroline A. Heckman, Jurjen Versluis, María Abáigar, Marta Anna Sobas, Raúl Azibeiro Melchor, Axel Benner, Peter JM Valk, Klaus H. Metzeler, Teresa González, Daniele Dall'Olio, Jesse M. Tettero, Javier Martinez Elicegui, Joaquín Martínez-López, Marta Pratcorona, Frederik Damm, Ken I Mills, Christian Thiede, Maria Teresa Voso, Guillermo Sanz, Konstanze Döhner, Michael Heuser, Torsten Haferlach, Amin T. Turki, Rubén Villoria Medina, Michel van Speybroeck, Renate Schulze-Rath, Martje Barbus, John E Butler, Jesús María Hernández-Rivas, Brian James Patrick Huntly, Gert Ossenkoppele, Hartmut Döhner, Lars Bullinger
Journal: Blood
Blood (2022) 140 (Supplement 1): 739–742.
https://doi.org/10.1182/blood-2022-167138
Published: 2022
Journal Articles

Long-Term Follow-up of AML Patients Treated Intensively before the Era of Targeted Agents. a Big Data Analysis from the Harmony Collaboration

Marta Anna Sobas, Angela Villaverde Ramiro, Alberto Hernández Sánchez, Javier Martinez Elicegui, Teresa González, Raúl Azibeiro Melchor, María Abáigar, Laura Tur, Daniele Dall'Olio, Eric Sträng, Jesse M. Tettero, Castellani Gastone, Axel Benner, Konstanze Döhner, Christian Thiede, Amin T. Turki, Klaus H. Metzeler, Torsten Haferlach, Frederick Damm, Rosa Ayala, Joaquín Martínez-López, Ken I Mills, Jorge Sierra, Sören Lehmann, Matteo G. Della Porta, Jiri Mayer, Dirk Reinhardt, Rubén Villoria Medina, Renate Schulze-Rath, Martje Barbus, Jesús María Hernández-Rivas, Brian James Patrick Huntly, Gert Ossenkoppele, Hartmut Dohner, Lars Bullinger
Journal: Blood
Blood (2022) 140 (Supplement 1): 6053–6055.
https://doi.org/10.1182/blood-2022-165088
Published: 2022
Journal Articles

Synthetic Data Generation By Artificial Intelligence to Accelerate Translational Research and Precision Medicine in Hematological Malignancies

Saverio D'Amico, Elisabetta Sauta, Matteo Bersanelli, Daniele Dall'Olio, Claudia Sala, Lorenzo Dall'Olio, Pierandrea Morandini, Tobia Tommasini, Marilena Bicchieri, Matteo Zampini, Victor Savevski, Iñigo Prada-Luengo, Anders Krogh, Uwe Platzbecker, Maria Diez-Campelo, Valeria Santini, Pierre Fenaux, Torsten Haferlach, Castellani Gastone, Matteo G. Della Porta
Journal: Blood
Blood (2022) 140 (Supplement 1): 9744–9746.
https://doi.org/10.1182/blood-2022-168646
Published: 2022
Journal Articles

Multi-Modal Analysis and Federated Learning Approach for Classification and Personalized Prognostic Assessment in Myeloid Neoplasms

Saverio D'Amico, Lorenzo Dall'Olio, Cesare Rollo, Patricia Alonso, Iñigo Prada-Luengo, Daniele Dall'Olio, Claudia Sala, Matteo Bersanelli, Elisabetta Sauta, Marilena Bicchieri, Pierandrea Morandini, Tobia Tommasini, Victor Savevski, Lin-Pierre Zhao, Uwe Platzbecker, Maria Diez-Campelo, Valeria Santini, Pierre Fenaux, Torsten Haferlach, Anders Krogh, Santiago Zazo, Piero Fariselli, Tiziana Sanavia, Matteo G. Della Porta, Castellani Gastone
Journal: Blood
Blood (2022) 140 (Supplement 1): 9828–9830.
https://doi.org/10.1182/blood-2022-166802
Published: 2022
Journal Articles

Rearrangements Involving 11q23/ KMT2A : Mutational Landscape and Prognostic Implications - Results of the Harmony Alliance AML Database

Alberto Hernández Sánchez, Teresa González, Marta Anna Sobas, Eric Sträng, Castellani Gastone, María Abáigar, Peter JM Valk, Angela Villaverde Ramiro, Axel Benner, Klaus H. Metzeler, Jesse M. Tettero, Joaquín Martínez-López, Marta Pratcorona, Javier Martinez Elicegui, Ken I Mills, Christian Thiede, Guillermo Sanz, Konstanze Döhner, Michael Heuser, Torsten Haferlach, Amin T. Turki, Dirk Reinhardt, Renate Schulze-Rath, Martje Barbus, Jesús María Hernández-Rivas, Brian James Patrick Huntly, Gert Ossenkoppele, Hartmut Döhner, Lars Bullinger
Journal: Blood
Blood (2022) 140 (Supplement 1): 551–554.
https://doi.org/10.1182/blood-2022-167480
Published: 2022
Journal Articles

Harmony Alliance Provides a Machine Learning Researching Tool to Predict the Risk of Relapse after First Remission in AML Patients Treated without Allogeneic Haematopoietic Stem Cell Transplantation

Marta Sobas, Javier Martinez Elicegui, Angela Villaverde Ramiro, Teresa González, Alberto Hernandez-Sanchez, Raúl Azibeiro Melchor, Axel Benner, Eric Sträng, Castellani Gastone, Caroline A. Heckman, Ana Heredia Casanoves, Jurjen Versluis, María Abáigar, Laura Jamilis, Peter JM Valk, Klaus H. Metzeler, Rosa Ayala, Joaquin Martinez Lopez, Hervé Dombret, Jorge Sierra, Claude Preudomme, Frederick Damm, Ken I Mills, Jiří Mayer, Christian Thiede, Maria Teresa Voso, Sergio Amadori, Guillermo Sanz, Frederico Calado, Konstanze Döhner, Verena I Gaidzik, Michael Heuser, Torsten Haferlach, Amin T. Turki, Dirk Reinhardt, Rubén Villoria Medina, Michel Van Speybroeck, Renate Schulze-Rath, John E Butler, Brian J.P Huntly, Hartmut Dohner, Gert J. Ossenkoppele, Lars Bullinger, Jesus Maria Hernández-Rivas
Journal: Blood
Blood (2021) 138 (Supplement 1): 4041.
https://doi.org/10.1182/blood-2021-149521
Published: 2021
Journal Articles

Impact of Gender on Molecular AML Subclasses - a Harmony Alliance Study

Tommaso Matteuzzi, Daniele Dall'Olio, Eric Sträng, Alessandra Merlotti, Javier Martinez Elicegui, Axel Benner, Maral Saadati, Julia Krzykalla, Caroline A. Heckman, Ana Heredia Casanoves, Jurjen Versluis, María Abáigar, Alberto Hernandez-Sanchez, Laura Jamilis, Peter JM Valk, Klaus H. Metzeler, Rosa Ayala, Joaquin Martinez Lopez, Herve Dombret, Pau Montesinos, Jorge Sierra, Claude Preudomme, Frederick Damm, Ken I Mills, Raúl Azibeiro Melchor, Jiří Mayer, Christian Thiede, Maria Teresa Voso, Sergio Amadori, Guillermo Sanz, Frederico Calado, Konstanze Döhner, Verena I Gaidzik, Michael Heuser, Torsten Haferlach, Marta Sobas, Amin T. Turki, Dirk Reinhardt, Rubén Villoria Medina, Michel van Speybroeck, Renate Schulze-Rath, Jesús M Hernández Rivas, Brian J.P Huntly, Hartmut Döhner, Gert J. Ossenkoppele, Castellani Gastone, Lars Bullinger
Journal: Blood
Blood (2021) 138 (Supplement 1): 3438.
https://doi.org/10.1182/blood-2021-152215
Published: 2021
Journal Articles

Does RAD21 Co-Mutation Have a Role in DNMT3A Mutated AML? Results of Harmony Alliance AML Database

Raúl Azibeiro Melchor, Alberto Hernández Sánchez, Teresa González, Marta Sobas, Javier Martinez Elicegui, Angela Villaverde Ramiro, Axel Benner, Eric Sträng, Castellani Gastone, Caroline A. Heckman, Ana Heredia Casanoves, Jurjen Versluis, María Abáigar, Laura Jamilis, Peter JM Valk, Klaus H. Metzeler, Rosa Ayala, Herve Dombret, Jorge Sierra, Claude Preudomme, Frederick Damm, Ken I Mills, Jiří Mayer, Christian Thiede, Maria Teresa Voso, Sergio Amadori, Guillermo Sanz, Frederico Calado, Konstanze Döhner, Verena I Gaidzik, Michael Heuser, Torsten Haferlach, Amin T. Turki, Dirk Reinhardt, Rubén Villoria Medina, Michel van Speybroeck, Renate Schulze-Rath, John E Butler, Brian J.P Huntly, Jesús M Hernández Rivas, Lars Bullinger, Hartmut Döhner, Gert J. Ossenkoppele
Journal: Blood
Blood (2021) 138 (Supplement 1): 608.
https://doi.org/10.1182/blood-2021-150766
Published: 2021
Journal Articles

A New Risk Stratification Model (R2-ISS) in Newly Diagnosed Multiple Myeloma: Analysis of Mature Data from 7077 Patients Collected By European Myeloma Network within Harmony Big Data Platform

Mattia D'Agostino, MD, Juan-José Lahuerta, MD PhD, Ruth Wester, MD, Anders Waage, MD PhD, Uta Bertsch, Elena Zamagni, Maria-Victoria Mateos, MD PhD, Alessandra Larocca, Daniele Dall'Olio, Niels W. C. J. van de Donk, David Cairns, MSc, PhD, Serena Rocchi, Hans Salwender, MD, Joan Blade Creixenti, Bronno van der Holt, PhD, Castellani Gastone, Giovannino Ciccone, Andrea Capra, Jan Dürig, MD, Sara Bringhen, MD, Sonja Zweegman, MDPhD, Michele Cavo, Hartmut Goldschmidt, MD, Gordon Cook, MB ChB, PhD, Jesus Maria Hernández-Rivas, MD PhD, Jesus F. San-Miguel, MD PhD, Mario Boccadoro, Pieter Sonneveld, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34–37.
https://doi.org/10.1182/blood-2020-137021
Published: 2020
Journal Articles

A New Gene Expression Profile Signature CRLF2 Overexpression Based Identifies Novel Adult "Triple Negative" Acute Lymphoblastic Leukemia Subgroups

Anna Ferrari, PhD, Silvia Vitali, PhD, Valentina Robustelli, PhD, Andrea Ghelli Luserna Di Rora, Simona Righi, Giovanni Pasquini, Cristina Papayannidis, Giovanni Marconi, Giulia Ferrari, Maria Chiara Fontana, MSc, Enrica Imbrogno, Eugenio Fonzi, PhD, Antonella Padella, Giorgia Simonetti, PhD, Alessandra Santoro, PhD, Jesús-María Hernández-Rivas, MD PhD, Michela Tebaldi, Samanta Salvi, Carmen Baldazzi, Maria Chiara Abbenante, Nicoletta Testoni, BSc, Massimiliano Bonafè, Castellani Gastone, Elena Sabattini, Michele Cavo, MD, Daniel Remondini, Giovanni Martinelli
Journal: Blood
Blood (2018) 132 (Supplement 1): 5284.
https://doi.org/10.1182/blood-2018-99-118062
Published: 2018