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Anja Seckinger
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Journal Articles

Implications and Prognostic Impact of Mass Spectrometry in Patients with Newly-Diagnosed Multiple Myeloma

Elias K Mai, Stefanie Huhn, Kaya Miah, Alexandra M Poos, Christof Scheid, Katja Weisel, Uta Bertsch, Markus Munder, Oscar Berlanga, Dirk Hose, Anja Seckinger, Anna Jauch, Igor Wolfgang Blau, Mathias Haenel, Hans Salwender, Axel Benner, Marc S Raab, Hartmut Goldschmidt, Niels Weinhold
Journal: Blood
Blood (2022) 140 (Supplement 1): 2341–2343.
https://doi.org/10.1182/blood-2022-156169
Published: 2022
Journal Articles

Gain 1q21 Is an Adverse Prognostic Factor in Patients with Relapsed/Refractory AL Amyloidosis Treated with Lenalidomide and Dexamethasone

Marco Basset, MD, Christoph Kimmich, Tobias Dittrich, MD, Kaya Veelken, MD, Hartmut Goldschmidt, MD, Dirk Hose, MD, Anja Seckinger, MD, Anna Jauch, Carsten Mueller-Tidow, MD, Ute Hegenbart, MD, Stefan Schönland, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17–18.
https://doi.org/10.1182/blood-2020-142701
Published: 2020
Journal Articles

Daratumumab for systemic AL amyloidosis: prognostic factors and adverse outcome with nephrotic-range albuminuria

Clinical Trials & Observations
Christoph R. Kimmich, Tobias Terzer, Axel Benner, Tobias Dittrich, Kaya Veelken, Alexander Carpinteiro, Timon Hansen, Hartmut Goldschmidt, Anja Seckinger, Dirk Hose, Anna Jauch, Stefan Wörner, Jörg Beimler, Carsten Müller-Tidow, Ute Hegenbart, Stefan O. Schönland
Journal: Blood
Blood (2020) 135 (18): 1517–1530.
https://doi.org/10.1182/blood.2019003633
Published: 2020
Includes: Supplemental data
Journal Articles

MCT1 As Molecularly Validated Predictive Marker for Lenalidomide-Maintenance Therapy in Multiple Myeloma

Jacob Stroh, Anja Seckinger, Michael Heider, Ruth Eichner, Martina Emde, Hans Salwender, Uta Bertsch, Hartmut Goldschmidt, MD, Katja Weisel, Christof Scheid, MD, Dirk Hose, MD, Florian Bassermann, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3187.
https://doi.org/10.1182/blood-2019-130734
Published: 2019
Journal Articles

Multiple Myeloma Pathogenesis: The Role of Junb in Bone Marrow Angiogenesis

Fengjuan Fan, PhD, Stefano Malvestiti, MD, Yujia Shen, PhD, Eugenio Morelli, MD, Yuji Mishima, MD, Anja Seckinger, Dirk Hose, MD, Latifa Bakiri, PhD, Sonia Vallet, MD, Martin Sattler, PhD, Aldo M. Roccaro, MD PhD, Hartmut Goldschmidt, MD, Martin Percherstorfer, MD, Chunyan Sun, MD PhD, Yu Hu, MD PhD, Erwin F Wagner, PhD, Piefrancesco Tassone, MD, Irene M. Ghobrial, MD, Dirk Jaeger, MD, Klaus Podar, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4341.
https://doi.org/10.1182/blood-2019-128854
Published: 2019
Journal Articles

Prediction of Malingant Plasma Cell Biology Related Survival in AL-Amyloidosis

Susanne Beck, Martina Emde, Jerome Moreaux, PhD, Anja Seckinger, Dirk Hose, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3078.
https://doi.org/10.1182/blood-2019-131161
Published: 2019
Journal Articles

RNA-Sequencing Based Assessment of Targets, Risk and Long Term Survival for Personalized Treatment of Multiple Myeloma

Martina Emde, Susanne Beck, Vladimir Benes, Jerome Moreaux, PhD, Anja Seckinger, Dirk Hose, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1801.
https://doi.org/10.1182/blood-2019-131159
Published: 2019
Journal Articles

Biallelic Inactivation of Multiple Tumor Suppressors Is Associated with Early Relapse after Stem Cell Transplant in Newly Diagnosed Myeloma

Niels Weinhold, PhD, Jing Xu, PhD, Martina Fröhlich, PhD, Alexandra M Poos, PhD, Lukas John, MD, Carsten Müller-Tidow, MD, Sandra Sauer, MD, Stefanie Huhn, PhD, Dirk Hose, MD, Anja Seckinger, Kari Hemminki, MD PhD, Benedikt Brors, PhD, Hartmut Goldschmidt, MD, Nicola Giesen, MD, Marc S Raab, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1783.
https://doi.org/10.1182/blood-2019-131195
Published: 2019
Journal Articles

A niche-dependent myeloid transcriptome signature defines dormant myeloma cells

Weng Hua Khoo, Guy Ledergor, Assaf Weiner, Daniel L. Roden, Rachael L. Terry, Michelle M. McDonald, Ryan C. Chai, Kim De Veirman, Katie L. Owen, Khatora S. Opperman, Kate Vandyke, Justine R. Clark, Anja Seckinger, Natasa Kovacic, Akira Nguyen, Sindhu T. Mohanty, Jessica A. Pettitt, Ya Xiao, Alexander P. Corr, Christine Seeliger, Mark Novotny, Roger S. Lasken, Tuan V. Nguyen, Babatunde O. Oyajobi, Dana Aftab, Alexander Swarbrick, Belinda Parker, Duncan R. Hewett, Dirk Hose, Karin Vanderkerken, Andrew C. W. Zannettino, Ido Amit, Tri Giang Phan, Peter I. Croucher
Journal: Blood
Blood (2019) 134 (1): 30–43.
https://doi.org/10.1182/blood.2018880930
Published: 2019
Includes: Supplemental data
Journal Articles

Treatment Response and Long-Term Survival in Multiple Myeloma in the GMMG-HD4 Trial - Neither Profit All Molecular Entities Alike, Nor Are Remissions to Different Regimen Equal

Anja Seckinger, Hans Jürgen Salwender, MD, Hans Martin, MD, Christof Scheid, Thomas Hielscher, Uta Bertsch, MD, Manuela Hummel, Anna Jauch, PhD, Wolfgang Knauf, Martina Emde, Susanne Beck, Kai Neben, Henk M. Lokhorst, MD PhD, Bronno van der Holt, PhD, Ulrich Duehrsen, MD, Jan Dürig, Hans-Walter Lindemann, MD, Ingo Schmidt-Wolf, Mathias Haenel, MD, Bernd Lathan, Marc S Raab, MD PhD, Carsten Müller-Tidow, MD, Pieter Sonneveld, MD PhD, Igor Wolfgang Blau, Jens Hillengass, MD, Katja Weisel, MD, Hartmut Goldschmidt, MD, Dirk Hose, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4485.
https://doi.org/10.1182/blood-2018-99-113284
Published: 2018
Journal Articles

AL Amyloidosis — Pathogenesis and Prognosis Are Determined By the Amyloidogenic Potential of the Light Chain and the Molecular Characteristics of Malignant Plasma Cells

Anja Seckinger, Ute Hegenbart, Susanne Beck, Martina Emde, Tilmann Bochtler, Christoph Kimmich, Carsten Müller-Tidow, MD, Anna Jauch, PhD, Stefan Schönland, Dirk Hose, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 187.
https://doi.org/10.1182/blood-2018-187
Published: 2018
Journal Articles

Quantitative Integrative Prediction of Survival Probability in Multiple Myeloma Using Molecular and Clinical Prognostic Factors in 657 Patients Treated with Bortezomib-Based Induction, High-Dose Therapy and Autologous Stem Cell Transplantation

Manuela Hummel, Thomas Hielscher, Hans Jürgen Salwender, MD, Christof Scheid, Hans Martin, MD, Uta Bertsch, MD, Hartmut Goldschmidt, MD, Anja Seckinger, Dirk Hose, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 403.
https://doi.org/10.1182/blood-2018-99-113307
Published: 2018
Journal Articles

Response-Adapted Lenalidomide Maintenance in Newly Diagnosed, Transplant-Eligible Multiple Myeloma: Results from the Multicenter Phase III GMMG-MM5 Trial

Hartmut Goldschmidt, MD, Elias K Mai, MD, Jan Dürig, MD, Christof Scheid, MD, Katja C. Weisel, Christina Kunz, Uta Bertsch, MD, Thomas Hielscher, PhD, Markus Munder, MD, Hans-Walter Lindemann, Barbara Huegle-Doerr, Dirk Hose, MD, Anja Seckinger, Stefanie Huhn, PhD, Anna Jauch, Bernhard Rabold, Ahmet Elmaagacli, MD, Christian Gerecke, MD, Peter Brossart, MD, Martin Goerner, MD, Helga Bernhard, MD, Martin Hoffmann, MD, Jens Hillengass, MD, Marc-Steffen S Raab, Igor Wolfgang Blau, MD, Mathias Hänel, MD, Hans Jürgen Salwender
Journal: Blood
Blood (2017) 130 (Supplement 1): 400.
https://doi.org/10.1182/blood.V130.Suppl_1.400.400
Published: 2017
Journal Articles

CD200 Is a Potent New Growth Factor in Multiple Myeloma through IGF-1R Interaction

Angélique Bruyer, MSc, Nicolas Robert, Stéphanie Boireau, Christophe Hirtz, Laurent Tiers, Laure Vincent, Guillaume Cartron, Dirk Hose, MD, Anja Seckinger, Bernard Klein, PhD, Jerome Moreaux, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3045.
https://doi.org/10.1182/blood.V130.Suppl_1.3045.3045
Published: 2017
Journal Articles

Direct Assessment of IgA and IgG Paraprotein By Hevylite Assay and Correlation to IMWG Response and Progression-Free Survival in Newly Diagnosed, Transplant-Eligible Multiple Myeloma Patients in the Prospective Phase III GMMG-MM5 Trial

Christof Scheid, MD, Anja Seckinger, Jan Dürig, MD, Katja C. Weisel, Christina Kunz, Uta Bertsch, MD, Thomas Hielscher, PhD, Markus Munder, MD, Hans-Walter Lindemann, Barbara Huegle-Doerr, Stefanie Huhn, PhD, Elias K Mai, MD, Anna Jauch, Bernhard Rabold, Christian Gerecke, MD, Peter Brossart, MD, Martin Goerner, MD, Helga Bernhard, MD, Martin Hoffmann, MD, Jens Hillengass, MD, Marc-Steffen S Raab, Igor Wolfgang Blau, MD, Mathias Haenel, Dirk Hose, MD, Hartmut Goldschmidt, MD, Hans Jürgen Salwender
Journal: Blood
Blood (2017) 130 (Supplement 1): 1784.
https://doi.org/10.1182/blood.V130.Suppl_1.1784.1784
Published: 2017
Journal Articles

Addition of Cyclophosphamide to Pomalidomide and Dexamethasone in Case of Suboptimal Response to Pomalidomide and Dexamethasone Alone in Relapsed and/or Refractory Multiple Myeloma: Results of the GMMG-Perspective Trial

Katja C. Weisel, Hans Jürgen Salwender, Christof Scheid, MD, Manola Zago, Britta Besemer, Mathias Hänel, MD, Jan Dürig, MD, Markus Munder, MD, Hans-Walter Lindemann, Anja Seckinger, Christina Kunz, Axel Benner, Dirk Hose, MD, Anna Jauch, Lothar Kanz, Hartmut Goldschmidt, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1849.
https://doi.org/10.1182/blood.V130.Suppl_1.1849.1849
Published: 2017
Journal Articles

Combined Inhibition of Chk1 and Wee1 As a New Therapeutic Strategy for High-Risk Multiple Myeloma Patients

Angelique Bruyer, Hugues de Boussac, PhD, Thibaut Martin, Alboukadel Kassambara, PhD, Nicolas Robert, Guillaume Cartron, Dirk Hose, MD, Anja Seckinger, Philippe Pasero, PhD, Jerome Moreaux, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1777.
https://doi.org/10.1182/blood.V130.Suppl_1.1777.1777
Published: 2017
Journal Articles

Kinome Expression Profiling in Multiple Myeloma Identifies New Therapeutic Targets

Hugues de Boussac, PhD, Angelique Bruyer, Nicolas Robert, Anke Maes, Laure Vincent, Anja Seckinger, Guillaume Cartron, Dirk Hose, MD, Elke De Bruyne, PhD, Alboukadel Kassambara, PhD, Jerome Moreaux, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1766.
https://doi.org/10.1182/blood.V130.Suppl_1.1766.1766
Published: 2017
Journal Articles

Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma

Michelle M. McDonald, Michaela R. Reagan, Scott E. Youlten, Sindhu T. Mohanty, Anja Seckinger, Rachael L. Terry, Jessica A. Pettitt, Marija K. Simic, Tegan L. Cheng, Alyson Morse, Lawrence M. T. Le, David Abi-Hanna, Ina Kramer, Carolyne Falank, Heather Fairfield, Irene M. Ghobrial, Paul A. Baldock, David G. Little, Michaela Kneissel, Karin Vanderkerken, J. H. Duncan Bassett, Graham R. Williams, Babatunde O. Oyajobi, Dirk Hose, Tri G. Phan, Peter I. Croucher
Journal: Blood
Blood (2017) 129 (26): 3452–3464.
https://doi.org/10.1182/blood-2017-03-773341
Published: 2017
Includes: Supplemental data
Journal Articles

Targeting EZH2 in Multiple Myeloma Could be Promising for a Subgroup of MM Patients in Combination with IMiDs

Laurie Herviou, Alboukadel Kassambara, PhD, Stephanie Boireau, PhD, Nicolas Robert, Guilhem Requirand, Laure Vincent, MD, Anja Seckinger, MD, Hartmut Goldschmidt, MD, Dirk Hose, MD, Giacomo Cavalli, PhD, Jerome Moreaux, PhD
Journal: Blood
Blood (2016) 128 (22): 311.
https://doi.org/10.1182/blood.V128.22.311.311
Published: 2016