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Andrew C. W. Zannettino
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Journal Articles

A niche-dependent myeloid transcriptome signature defines dormant myeloma cells

Weng Hua Khoo, Guy Ledergor, Assaf Weiner, Daniel L. Roden, Rachael L. Terry, Michelle M. McDonald, Ryan C. Chai, Kim De Veirman, Katie L. Owen, Khatora S. Opperman, Kate Vandyke, Justine R. Clark, Anja Seckinger, Natasa Kovacic, Akira Nguyen, Sindhu T. Mohanty, Jessica A. Pettitt, Ya Xiao, Alexander P. Corr, Christine Seeliger, Mark Novotny, Roger S. Lasken, Tuan V. Nguyen, Babatunde O. Oyajobi, Dana Aftab, Alexander Swarbrick, Belinda Parker, Duncan R. Hewett, Dirk Hose, Karin Vanderkerken, Andrew C. W. Zannettino, Ido Amit, Tri Giang Phan, Peter I. Croucher
Journal: Blood
Blood (2019) 134 (1): 30–43.
https://doi.org/10.1182/blood.2018880930
Published: 2019
Includes: Supplemental data
Journal Articles

Whole Exome Sequencing of Paired MGUS/SMM to MM Patients Reveals Novel Subclonal Tumour Evolution Models in Disease Progression of Multiple Myeloma

Ankit K. Dutta, John P. Grady, BSc, MSc, PhD, Duncan R. Hewett, BA (Hons), PhD, Luen Bik To, MBBS, FRACP, FRCPA, PhD, Lynn Fink, PhD, Andrew C. W. Zannettino, BSc (Hons), PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 391.
https://doi.org/10.1182/blood.V130.Suppl_1.391.391
Published: 2017
Journal Articles

HIF-2α Upregulates CCR1 to Promote Dissemination of Plasma Cells in Multiple Myeloma

Mara N Zeissig, BSc, Duncan R. Hewett, BA (Hons), PhD, Sally Martin, PhD, Krzysztof M Mrozik, BSc, Chee Man Cheong, PhD, Peter Diamond, PhD, Luen Bik To, MBBS, FRACP, FRCPA, PhD, Stan Gronthos, PhD, Daniel J Peet, PhD, Peter I Croucher, BSc, PhD, Kate Vandyke, PhD, Andrew C. W. Zannettino, BSc (Hons), PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4425.
https://doi.org/10.1182/blood.V130.Suppl_1.4425.4425
Published: 2017
Journal Articles

In Vitro Modeling of Ph-like ALL Fusions Identifies Novel Kinase-Domain Mutations As Mode of TKI-Resistance - Implications for Targeted Therapy

Kartini Asari, Susan L Heatley, PhD MD, Teresa Sadras, PhD, Tamara M Leclercq, PhD, Stephen Fitter, PhD, Chung Hoow Kok, PhD, Andrew C W Zannettino, PhD, Timothy P. Hughes, MD FRACP, FRCPA, MBBS, Deborah L White, PhD FFSc (RCPA)
Journal: Blood
Blood (2016) 128 (22): 3957.
https://doi.org/10.1182/blood.V128.22.3957.3957
Published: 2016
Journal Articles

Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches

Ingrid G. Winkler, Valérie Barbier, Robert Wadley, Andrew C. W. Zannettino, Sharon Williams, Jean-Pierre Lévesque
Journal: Blood
Blood (2010) 116 (3): 375–385.
https://doi.org/10.1182/blood-2009-07-233437
Published: 2010
Includes: Supplemental data
Journal Articles

Dysregulation of bone remodeling by imatinib mesylate

Kate Vandyke, Stephen Fitter, Andrea L. Dewar, Timothy P. Hughes, Andrew C. W. Zannettino
Journal: Blood
Blood (2010) 115 (4): 766–774.
https://doi.org/10.1182/blood-2009-08-237404
Published: 2010
Journal Articles

Reduced Activity of the OCT-1 Protein in Primitive CML Cells: A Likely Determinant of Stem Cell Resistance in Imatinib Treated CML Patients

Jane R Engler, Amity Frede, Andrew C W Zannettino, PhD, Deborah L White, PhD, Timothy P Hughes, MD
Journal: Blood
Blood (2008) 112 (11): 196.
https://doi.org/10.1182/blood.V112.11.196.196
Published: 2008
Journal Articles

Does Apo2L/TRAIL play any physiologic role in osteoclastogenesis?

Agatha Labrinidis, Vasilios Liapis, Le M. Thai, Gerald J. Atkins, Cristina Vincent, Shelley Hay, Natalie A. Sims, Andrew C. W. Zannettino, David M. Findlay, Andreas Evdokiou
Journal: Blood
Blood (2008) 111 (11): 5411–5412.
https://doi.org/10.1182/blood-2008-03-144261
Published: 2008
Journal Articles

Long-term imatinib therapy promotes bone formation in CML patients

Clinical Trials & Observations
Stephen Fitter, Andrea L. Dewar, Panagiota Kostakis, L. Bik To, Timothy P. Hughes, Marion M. Roberts, Kevin Lynch, Barrie Vernon-Roberts, Andrew C. W. Zannettino
Journal: Blood
Blood (2008) 111 (5): 2538–2547.
https://doi.org/10.1182/blood-2007-07-104281
Published: 2008
Includes: Supplemental data
Journal Articles

OCT-1–mediated influx is a key determinant of the intracellular uptake of imatinib but not nilotinib (AMN107): reduced OCT-1 activity is the cause of low in vitro sensitivity to imatinib

Deborah L. White, Verity A. Saunders, Phuong Dang, Jane Engler, Andrew C. W. Zannettino, Antony C. Cambareri, Steven R. Quinn, Paul W. Manley, Timothy P. Hughes
Journal: Blood
Blood (2006) 108 (2): 697–704.
https://doi.org/10.1182/blood-2005-11-4687
Published: 2006
Journal Articles

Imatinib as a potential antiresorptive therapy for bone disease

Andrea L. Dewar, Amanda N. Farrugia, Mark R. Condina, L. Bik To, Timothy P. Hughes, Barrie Vernon-Roberts, Andrew C. W. Zannettino
Journal: Blood
Blood (2006) 107 (11): 4334–4337.
https://doi.org/10.1182/blood-2005-09-3568
Published: 2006
Journal Articles

Macrophage colony-stimulating factor receptor c-fms is a novel target of imatinib

Andrea L. Dewar, Antony C. Cambareri, Andrew C. W. Zannettino, Bernadette L. Miller, Kathleen V. Doherty, Timothy P. Hughes, A. Bruce Lyons
Journal: Blood
Blood (2005) 105 (8): 3127–3132.
https://doi.org/10.1182/blood-2004-10-3967
Published: 2005
Journal Articles

Functionally defined CD164 epitopes are expressed on CD34 + cells throughout ontogeny but display distinct distribution patterns in adult hematopoietic and nonhematopoietic tissues

Suzanne M. Watt, Lisa H. Butler, Manuela Tavian, Hans-Jörg Bühring, Irene Rappold, Paul J. Simmons, Andrew C. W. Zannettino, David Buck, Anja Fuchs, Regis Doyonnas, James Yi-Hsin Chan, Jean-Pierre Levesque, Bruno Peault, Ioannis Roxanis
Journal: Blood
Blood (2000) 95 (10): 3113–3124.
https://doi.org/10.1182/blood.V95.10.3113
Published: 2000