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Lothar Kanz
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Journal Articles

Predictive Value of Minimal Residual Disease on Efficacy of Rituximab Maintenance in Mantle Cell Lymphoma: Results from the European MCL Elderly Trial

Eva Hoster, Marie-Helene Delfau, Elizabeth A. Macintyre, Linmiao Jiang, Stephan Stilgenbauer, Ursula Vehling-Kaiser, Gilles Salles, Catherine Thieblemont, Hervé Tilly, Lothar Kanz, Pierre Feugier, Kai Huebel, Christian Schmidt, Vincent Ribrag, Hanneke Kluin-Nelemans, Martin Dreyling, Christiane Pott
Journal: Blood
Blood (2022) 140 (Supplement 1): 1304–1306.
https://doi.org/10.1182/blood-2022-159932
Published: 2022
Journal Articles

The HLA ligandome landscape of chronic myeloid leukemia delineates novel T-cell epitopes for immunotherapy

Tatjana Bilich, Annika Nelde, Leon Bichmann, Malte Roerden, Helmut R. Salih, Daniel J. Kowalewski, Heiko Schuster, Chih-Chiang Tsou, Ana Marcu, Marian C. Neidert, Maren Lübke, Jonas Rieth, Mirle Schemionek, Tim H. Brümmendorf, Vladan Vucinic, Dietger Niederwieser, Jens Bauer, Melanie Märklin, Janet K. Peper, Reinhild Klein, Oliver Kohlbacher, Lothar Kanz, Hans-Georg Rammensee, Stefan Stevanović, Juliane S. Walz
Journal: Blood
Blood (2019) 133 (6): 550–565.
https://doi.org/10.1182/blood-2018-07-866830
Published: 2019
Includes: Supplemental data
Journal Articles

The HLA Ligandome Landscape of Chronic Myeloid Leukemia Delineates Novel T-Cell Epitopes for Immunotherapy

Tatjana Bilich, Annika Nelde, Leon Bichmann, Helmut R. Salih, MD, Daniel Johannes Kowalewski, Heiko Schuster, Ana Marcu, Marian C. Neidert, Maren Lübke, Jonas Rieth, Mirle Schemionek, Tim H Brümmendorf, MD, Vladan Vucinic, MD, Dietger Niederwieser, MD, Melanie Märklin, PhD, Janet K. Peper, Malte Roerden, Reinhild Klein, Oliver Kohlbacher, Lothar Kanz, Hans-Georg Rammensee, Stefan Stevanovic, Juliane S. Walz
Journal: Blood
Blood (2018) 132 (Supplement 1): 4243.
https://doi.org/10.1182/blood-2018-99-113376
Published: 2018
Journal Articles

Inhibition of DOT1L and PRMT5 Promotes Anti-Tumor Activity in a Human MLL Leukemia Model Induced By CRISPR/Cas9

Kathy-Ann Secker, MSc, Hildegard Keppeler, Silke Duerr-Stoerzer, Hannes Schmid, MSc, Dominik Schneidawind, MD, Thomas Hentrich, PhD, Julia Schulze-Hentrich, PhD, Barbara Mankel, Falko Fend, MD, Lothar Kanz, Corina Schneidawind, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5147.
https://doi.org/10.1182/blood-2018-99-115975
Published: 2018
Journal Articles

Immunocytokines with Target Cell-Restricted IL-15 Activity for Induction of NK Cell Reactivity Against Acute Myeloid Leukemia (AML)

Bastian J. Schmied, MSc, Latifa Zekri, PhD, Martin Pflügler, PhD, Melanie Märklin, PhD, Lothar Kanz, Gundram Jung, Prof., MD, Helmut R. Salih, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 731.
https://doi.org/10.1182/blood-2018-99-112485
Published: 2018
Journal Articles

Excellent Outcome of Young Patients (18-60 years) with Favourable-Prognosis Diffuse Large B-Cell Lymphoma (DLBCL) Treated with 4 Cycles CHOP Plus 6 Applications of Rituximab: Results of the 592 Patients of the Flyer Trial of the Dshnhl/GLA

Viola Poeschel, MD, Gerhard Held, MD, Marita Ziepert, PhD, Bettina Altmann, PhD, Mathias Witzens-Harig, MD, Harald Holte, MD PhD, Lorenz Thurner, MD, Andreas Viardot, MD, Peter Borchmann, MD, Lothar Kanz, Ulrich Keller, Christian Schmidt, MD, Rolf Mahlberg, MD, Bernd Metzner, MDPhD, Reinhard Marks, Heinz-Gert Hoeffkes, MD, Konstantinos Christofyllakis, MD, Josif Amam, Christian Berdel, MD, Stephan Stilgenbauer, Norbert Schmitz, MD, Lorenz Truemper, MD, Niels Murawski, MD, Markus Loeffler, MD, Michael Pfreundschuh, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 781.
https://doi.org/10.1182/blood-2018-99-112403
Published: 2018
Journal Articles

Absence of NKG2D Ligands Defines Human Acute Myeloid Leukaemia Stem Cells and Mediates Their Immune Evasion

Anna M Paczulla, PhD, Kathrin Rothfelder, PhD, Simon Raffel, MD, Martina Konantz, PhD, Julia Steinbacher, PhD, Hui Wang, PhD, Marcelle Ndoh Mbarga, Thorsten Schaefer, PhD, Daniela Dörfel, MD, Mattia Falcone, Eva Nievergall, PhD, Claudia Tandler, MSc, Christoph Lutz, Pontus Lundberg, PhD, Lothar Kanz, Leticia Quintanilla-Martinez, MD, Alexander Steinle, Andreas Trumpp, Prof, PhD, Helmut R. Salih, MD, Claudia Lengerke, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 769.
https://doi.org/10.1182/blood-2018-99-118047
Published: 2018
Journal Articles

Invariant Natural Killer T Cells from Donor Lymphocyte Infusions (DLI-iNKTs) Contribute to Anti-Tumor Immunity after Allogeneic Hematopoietic Cell Transplantation

Simona Jahnke, Hannes Schmid, MSc, Kathy-Ann Secker, MSc, Silke Duerr-Stoerzer, Hildegard Keppeler, Rebecca Baur, Michael Schumm, Dr. MD vet., Rupert Handgretinger, MD PhD, Wolfgang Bethge, MD, Lothar Kanz, Corina Schneidawind, MD, Dominik Schneidawind, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3340.
https://doi.org/10.1182/blood-2018-99-111745
Published: 2018
Journal Articles

Improving Treatment Related Mortality over Time - Data from the Non-Observational Trial on Autologous Stem Cell Transplantation in Systemic Sclerosis By the EBMT Autoimmune Diseases Working Party (ADWP)

Dominique Farge, PhD MD, John A Snowden, MD PhD, Manuela Badoglio, Myriam Labopin, MD, Hans Ulrich Scherer, MD PhD, Nicoletta Del Papa, PhD MD, Lothar Kanz, Marc Schmalzing, MD, Thierry Martin, MD PhD, Montserrat Rovira, MD, Thomas Daikeler, MD PhD, Gregory Pugnet, MD PhD, Joerg Henes, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3431.
https://doi.org/10.1182/blood-2018-99-116602
Published: 2018
Journal Articles

Analysis of the Multiple Myeloma HLA Peptidome Identifies a Naturally Presented Bcma-Derived Peptide As an Immunogenic T-Cell Epitope for Immunotherapeutic Approaches

Tatjana Bilich, Simon D. Walz, Annika Nelde, Helmut R. Salih, MD, Ana Marcu, Daniel Johannes Kowalewski, Katja Weisel, MD, Lothar Kanz, Hans-Georg Rammensee, Stefan Stevanovic, Juliane S. Walz
Journal: Blood
Blood (2018) 132 (Supplement 1): 3173.
https://doi.org/10.1182/blood-2018-99-113473
Published: 2018
Journal Articles

Myc Drives MLL Leukemogenesis in a Human CRISPR/Cas9 Leukemia Model and Indirect Inhibition with JQ1 Diminishes Leukemia Activity

Kathy-Ann Secker, MSc, Hildegard Keppeler, Silke Duerr-Stoerzer, Hannes Schmid, MSc, Dominik Schneidawind, MD, Thomas Hentrich, PhD, Julia Schulze-Hentrich, PhD, Lothar Kanz, Corina Schneidawind, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2213.
https://doi.org/10.1182/blood-2018-99-114419
Published: 2018
Journal Articles

A Method to Fluorescently Label the CRISPR/Cas9-gRNA RNP Complexes Enables Enrichment of Clinical-Grade Gene-Edited Primary Hematopoietic Stem Cells and iPSCs

Masoud Nasri, Perihan Mir, Benjamin Dannenmann, Diana Amend, Yun Xu, Anna Solovyeva, Sylwia Stefanczyk, Maksim Klimiankou, Cornelia Zeidler, Lothar Kanz, Karl Welte, Julia Skokowa, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1108.
https://doi.org/10.1182/blood-2018-99-114844
Published: 2018
Journal Articles

Radiofrequency Ablation of Liver Metastases from Colorectal Cancer Induces a Cancer-Specific T Cell Repertoire in Humans

Markus W. Loeffler, Bianca Nussbaum, Philipp S. Jurmeister, MD, Jan Budczies, Daniel Johannes Kowalewski, Stephan Clasen, Ingmar Koenigsrainer, Stefan Beckert, Silvia Wagner, Bence Sipos, Florian Bullinger, Olaf H. Riess, Philippe Pereira, Alfred Koenigsrainer, Lothar Kanz, Stefan Stevanovic, Carsten Denkert, Hans-Georg Rammensee, Cecile Gouttefangeas, Sebastian Haen, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1120.
https://doi.org/10.1182/blood-2018-99-120381
Published: 2018
Journal Articles

Mechanism of BAALC-Mediated Leukemogenesis Downstream of RUNX1 -Mutations in Severe Congenital Neutropenia

Benjamin Dannenmann, Maksim Klimiankou, Benedikt Oswald, Malte U Ritter, Masoud Nasri, Anna Solovyeva, Lothar Kanz, Cornelia Zeidler, Karl Welte, Julia Skokowa, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 13.
https://doi.org/10.1182/blood-2018-99-118558
Published: 2018
Journal Articles

GADD45b Plays an Essential Role in the G-CSF Triggered Granulocytic Differentiation of Human Hematopoietic Cells

Perihan Mir, Masoud Nasri, Benjamin Dannenmann, Maksim Klimiankou, Betuel Findik, Regine Bernhard, Michael A. Rieger, Cornelia Zeidler, Lothar Kanz, Karl Welte, Julia Skokowa, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 17.
https://doi.org/10.1182/blood-2018-99-114875
Published: 2018
Journal Articles

Mass Spectrometry-Based Immunopeptidome Analysis of Acute Myeloid Leukemia Cells Under Decitabine Treatment Delineates Induced Presentation of Cancer/Testis Antigens on HLA Class I Molecules

Jens Bauer, Nora Zieger, Annika Nelde, Leon Bichmann, Helmut R. Salih, MD, Lothar Kanz, Hans-Georg Rammensee, Stefan Stevanovic, Juliane S. Walz
Journal: Blood
Blood (2018) 132 (Supplement 1): 5223.
https://doi.org/10.1182/blood-2018-99-113357
Published: 2018
Journal Articles

Understanding the Role of CSF3R and Runx1 Runt Homology Domain Missense Mutations in Leukemic Transformation of Hematopoietic Stem Cells

Malte U Ritter, Olga Klimenkova, Maksim Klimiankou, Amy E Schmidt, MDPhD, Carol Stocking, PhD, Lothar Kanz, Cornelia Zeidler, Daniel C. Link, MD, Karl Welte, Julia Skokowa, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1101.
https://doi.org/10.1182/blood-2018-99-118644
Published: 2018
Journal Articles

Final Evaluation of Randomized CML-Study IV: 10-Year Survival and Evolution of Terminal Phase

Rüdiger Hehlmann, MD, Michael Lauseker, PhD, Susanne Saussele, MD, Markus Pfirrmann, Stefan W. Krause, MD, Hans-Jochem Kolb, MD, Andreas Neubauer, MD, Dieter K. Hossfeld, Christoph Nerl, MD, Alois Gratwohl, MD, Gabriela M. Baerlocher, Dominik Heim, MD, Tim Henrik Bruemmendorf, Alice Fabarius, PhD, Claudia Haferlach, MD, Brigitte Schlegelberger, MD PhD, Martin C. Müller, MD, Sabine Jeromin, PhD, Ulrike Proetel, PhD, Katharina Kohlbrenner, PhD, Astghik Voskanyan, PhD, Sébastien Rinaldetti, Wolfgang Seifarth, PhD, Birgit Spiess, Leopold Balleisen, MD, Maria E Goebeler, MD, Mathias Hänel, MD, Anthony D. Ho, MD, J Dengler, C Falge, Lothar Kanz, MD, Claus-Henning Köhne, MD, PhD, Andreas Burchert, MD, Michael Kneba, MD PhD, Frank Stegelmann, MD, C Köhne, Hans-Walter Lindemann, C Waller, Michael Pfreundschuh, MD, Karsten Spiekermann, Wolfgang E Berdel, MD, L Müller, Matthias Edinger, MD, Jiri Mayer, Prof, MD SCs, Dietrich W Beelen, MD PhD, Martin Bentz, MD, Hartmut Link, MDPhD, Bernd Hertenstein, MD, R Fuchs, Martin Wernli, MD, F Schlegel, Rudolph Schlag, M de Wit, Lorenz Trümper, MD, H Hebarth, M Hahn, Jörg Thomalla, MD, Christof Scheid, MD, Philippe Schafhausen, MD, Walter Verbeek, MD, Michael J. Eckart, MD, Winfried Gassmann, MD PhD, Antonio Pezzutto, MD, Michael Schenk, Peter Brossart, MD, Thomas Geer, MD, Stephan Bildat, E Schäfer, Andreas Hochhaus, MD, Joerg Hasford
Journal: Blood
Blood (2017) 130 (Supplement 1): 897.
https://doi.org/10.1182/blood.V130.Suppl_1.897.897
Published: 2017
Journal Articles

Lck Is a Crucial Anergy Regulator in CLL

Alexander Fuchs, Melanie Märklin, PhD, Jonas Heitmann, Felicia Truckenmüller, Sebastian Jonas Saur, MD, Manuela Ganser, Stefanie Bugl, Ursula Kohlhofer, Leticia Quintanilla-Martinez, MD, Hans-Georg Kopp, MD, Lothar Kanz, Anjana Rao, PhD, Stefan Wirths, MD, Martin R. Mueller, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3003.
https://doi.org/10.1182/blood.V130.Suppl_1.3003.3003
Published: 2017
Journal Articles

Haplo-Identical Stem Cell Transplantation for Patients with Multiple Myeloma Who Relapsed after Autografting. a Study from the Cmwp of EBMT

Nicolaus Kroeger, Diderik-Jan Eikema, Nina Simone Knelange, Yener Koc, Jose M Moraleda, Peter Dreger, MD, Harry C. Schouten, MD, Lothar Kanz, Johanna Tischer, MD, Paolo Corradini, MD, Hendrik Veelken, MD PhD, Michel Schaap, MD PhD, Tsila Zuckerman, MD, Liisa Volin, Nigel H. Russell, Pavel Jindra, MD PhD, Yves Beguin, MD PhD, Gerhard Ehninger, Fabio Ciceri, MD, Didier Blaise, Jose L. Diez-Martin, MD PhD, Eefke Petersen, MD, Stefan Schönland, MD, Laurent Garderet, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2046.
https://doi.org/10.1182/blood.V130.Suppl_1.2046.2046
Published: 2017