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Lothar Kanz
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Journal Articles

Predictive Value of Minimal Residual Disease on Efficacy of Rituximab Maintenance in Mantle Cell Lymphoma: Results from the European MCL Elderly Trial

Eva Hoster, Marie-Helene Delfau, Elizabeth A. Macintyre, Linmiao Jiang, Stephan Stilgenbauer, Ursula Vehling-Kaiser, Gilles Salles, Catherine Thieblemont, Hervé Tilly, Lothar Kanz, Pierre Feugier, Kai Huebel, Christian Schmidt, Vincent Ribrag, Hanneke Kluin-Nelemans, Martin Dreyling, Christiane Pott
Journal: Blood
Blood (2022) 140 (Supplement 1): 1304–1306.
https://doi.org/10.1182/blood-2022-159932
Published: 2022
Journal Articles

The HLA ligandome landscape of chronic myeloid leukemia delineates novel T-cell epitopes for immunotherapy

Tatjana Bilich, Annika Nelde, Leon Bichmann, Malte Roerden, Helmut R. Salih, Daniel J. Kowalewski, Heiko Schuster, Chih-Chiang Tsou, Ana Marcu, Marian C. Neidert, Maren Lübke, Jonas Rieth, Mirle Schemionek, Tim H. Brümmendorf, Vladan Vucinic, Dietger Niederwieser, Jens Bauer, Melanie Märklin, Janet K. Peper, Reinhild Klein, Oliver Kohlbacher, Lothar Kanz, Hans-Georg Rammensee, Stefan Stevanović, Juliane S. Walz
Journal: Blood
Blood (2019) 133 (6): 550–565.
https://doi.org/10.1182/blood-2018-07-866830
Published: 2019
Includes: Supplemental data
Journal Articles

Analysis of the Multiple Myeloma HLA Peptidome Identifies a Naturally Presented Bcma-Derived Peptide As an Immunogenic T-Cell Epitope for Immunotherapeutic Approaches

Tatjana Bilich, Simon D. Walz, Annika Nelde, Helmut R. Salih, MD, Ana Marcu, Daniel Johannes Kowalewski, Katja Weisel, MD, Lothar Kanz, Hans-Georg Rammensee, Stefan Stevanovic, Juliane S. Walz
Journal: Blood
Blood (2018) 132 (Supplement 1): 3173.
https://doi.org/10.1182/blood-2018-99-113473
Published: 2018
Journal Articles

Invariant Natural Killer T Cells from Donor Lymphocyte Infusions (DLI-iNKTs) Contribute to Anti-Tumor Immunity after Allogeneic Hematopoietic Cell Transplantation

Simona Jahnke, Hannes Schmid, MSc, Kathy-Ann Secker, MSc, Silke Duerr-Stoerzer, Hildegard Keppeler, Rebecca Baur, Michael Schumm, Dr. MD vet., Rupert Handgretinger, MD PhD, Wolfgang Bethge, MD, Lothar Kanz, Corina Schneidawind, MD, Dominik Schneidawind, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3340.
https://doi.org/10.1182/blood-2018-99-111745
Published: 2018
Journal Articles

Improving Treatment Related Mortality over Time - Data from the Non-Observational Trial on Autologous Stem Cell Transplantation in Systemic Sclerosis By the EBMT Autoimmune Diseases Working Party (ADWP)

Dominique Farge, PhD MD, John A Snowden, MD PhD, Manuela Badoglio, Myriam Labopin, MD, Hans Ulrich Scherer, MD PhD, Nicoletta Del Papa, PhD MD, Lothar Kanz, Marc Schmalzing, MD, Thierry Martin, MD PhD, Montserrat Rovira, MD, Thomas Daikeler, MD PhD, Gregory Pugnet, MD PhD, Joerg Henes, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3431.
https://doi.org/10.1182/blood-2018-99-116602
Published: 2018
Journal Articles

Mass Spectrometry-Based Immunopeptidome Analysis of Acute Myeloid Leukemia Cells Under Decitabine Treatment Delineates Induced Presentation of Cancer/Testis Antigens on HLA Class I Molecules

Jens Bauer, Nora Zieger, Annika Nelde, Leon Bichmann, Helmut R. Salih, MD, Lothar Kanz, Hans-Georg Rammensee, Stefan Stevanovic, Juliane S. Walz
Journal: Blood
Blood (2018) 132 (Supplement 1): 5223.
https://doi.org/10.1182/blood-2018-99-113357
Published: 2018
Journal Articles

Immunocytokines with Target Cell-Restricted IL-15 Activity for Induction of NK Cell Reactivity Against Acute Myeloid Leukemia (AML)

Bastian J. Schmied, MSc, Latifa Zekri, PhD, Martin Pflügler, PhD, Melanie Märklin, PhD, Lothar Kanz, Gundram Jung, Prof., MD, Helmut R. Salih, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 731.
https://doi.org/10.1182/blood-2018-99-112485
Published: 2018
Journal Articles

Excellent Outcome of Young Patients (18-60 years) with Favourable-Prognosis Diffuse Large B-Cell Lymphoma (DLBCL) Treated with 4 Cycles CHOP Plus 6 Applications of Rituximab: Results of the 592 Patients of the Flyer Trial of the Dshnhl/GLA

Viola Poeschel, MD, Gerhard Held, MD, Marita Ziepert, PhD, Bettina Altmann, PhD, Mathias Witzens-Harig, MD, Harald Holte, MD PhD, Lorenz Thurner, MD, Andreas Viardot, MD, Peter Borchmann, MD, Lothar Kanz, Ulrich Keller, Christian Schmidt, MD, Rolf Mahlberg, MD, Bernd Metzner, MDPhD, Reinhard Marks, Heinz-Gert Hoeffkes, MD, Konstantinos Christofyllakis, MD, Josif Amam, Christian Berdel, MD, Stephan Stilgenbauer, Norbert Schmitz, MD, Lorenz Truemper, MD, Niels Murawski, MD, Markus Loeffler, MD, Michael Pfreundschuh, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 781.
https://doi.org/10.1182/blood-2018-99-112403
Published: 2018
Journal Articles

The HLA Ligandome Landscape of Chronic Myeloid Leukemia Delineates Novel T-Cell Epitopes for Immunotherapy

Tatjana Bilich, Annika Nelde, Leon Bichmann, Helmut R. Salih, MD, Daniel Johannes Kowalewski, Heiko Schuster, Ana Marcu, Marian C. Neidert, Maren Lübke, Jonas Rieth, Mirle Schemionek, Tim H Brümmendorf, MD, Vladan Vucinic, MD, Dietger Niederwieser, MD, Melanie Märklin, PhD, Janet K. Peper, Malte Roerden, Reinhild Klein, Oliver Kohlbacher, Lothar Kanz, Hans-Georg Rammensee, Stefan Stevanovic, Juliane S. Walz
Journal: Blood
Blood (2018) 132 (Supplement 1): 4243.
https://doi.org/10.1182/blood-2018-99-113376
Published: 2018
Journal Articles

Inhibition of DOT1L and PRMT5 Promotes Anti-Tumor Activity in a Human MLL Leukemia Model Induced By CRISPR/Cas9

Kathy-Ann Secker, MSc, Hildegard Keppeler, Silke Duerr-Stoerzer, Hannes Schmid, MSc, Dominik Schneidawind, MD, Thomas Hentrich, PhD, Julia Schulze-Hentrich, PhD, Barbara Mankel, Falko Fend, MD, Lothar Kanz, Corina Schneidawind, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5147.
https://doi.org/10.1182/blood-2018-99-115975
Published: 2018
Journal Articles

Understanding the Role of CSF3R and Runx1 Runt Homology Domain Missense Mutations in Leukemic Transformation of Hematopoietic Stem Cells

Malte U Ritter, Olga Klimenkova, Maksim Klimiankou, Amy E Schmidt, MDPhD, Carol Stocking, PhD, Lothar Kanz, Cornelia Zeidler, Daniel C. Link, MD, Karl Welte, Julia Skokowa, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1101.
https://doi.org/10.1182/blood-2018-99-118644
Published: 2018
Journal Articles

A Method to Fluorescently Label the CRISPR/Cas9-gRNA RNP Complexes Enables Enrichment of Clinical-Grade Gene-Edited Primary Hematopoietic Stem Cells and iPSCs

Masoud Nasri, Perihan Mir, Benjamin Dannenmann, Diana Amend, Yun Xu, Anna Solovyeva, Sylwia Stefanczyk, Maksim Klimiankou, Cornelia Zeidler, Lothar Kanz, Karl Welte, Julia Skokowa, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1108.
https://doi.org/10.1182/blood-2018-99-114844
Published: 2018
Journal Articles

Radiofrequency Ablation of Liver Metastases from Colorectal Cancer Induces a Cancer-Specific T Cell Repertoire in Humans

Markus W. Loeffler, Bianca Nussbaum, Philipp S. Jurmeister, MD, Jan Budczies, Daniel Johannes Kowalewski, Stephan Clasen, Ingmar Koenigsrainer, Stefan Beckert, Silvia Wagner, Bence Sipos, Florian Bullinger, Olaf H. Riess, Philippe Pereira, Alfred Koenigsrainer, Lothar Kanz, Stefan Stevanovic, Carsten Denkert, Hans-Georg Rammensee, Cecile Gouttefangeas, Sebastian Haen, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1120.
https://doi.org/10.1182/blood-2018-99-120381
Published: 2018
Journal Articles

Mechanism of BAALC-Mediated Leukemogenesis Downstream of RUNX1 -Mutations in Severe Congenital Neutropenia

Benjamin Dannenmann, Maksim Klimiankou, Benedikt Oswald, Malte U Ritter, Masoud Nasri, Anna Solovyeva, Lothar Kanz, Cornelia Zeidler, Karl Welte, Julia Skokowa, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 13.
https://doi.org/10.1182/blood-2018-99-118558
Published: 2018
Journal Articles

Myc Drives MLL Leukemogenesis in a Human CRISPR/Cas9 Leukemia Model and Indirect Inhibition with JQ1 Diminishes Leukemia Activity

Kathy-Ann Secker, MSc, Hildegard Keppeler, Silke Duerr-Stoerzer, Hannes Schmid, MSc, Dominik Schneidawind, MD, Thomas Hentrich, PhD, Julia Schulze-Hentrich, PhD, Lothar Kanz, Corina Schneidawind, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2213.
https://doi.org/10.1182/blood-2018-99-114419
Published: 2018
Journal Articles

Absence of NKG2D Ligands Defines Human Acute Myeloid Leukaemia Stem Cells and Mediates Their Immune Evasion

Anna M Paczulla, PhD, Kathrin Rothfelder, PhD, Simon Raffel, MD, Martina Konantz, PhD, Julia Steinbacher, PhD, Hui Wang, PhD, Marcelle Ndoh Mbarga, Thorsten Schaefer, PhD, Daniela Dörfel, MD, Mattia Falcone, Eva Nievergall, PhD, Claudia Tandler, MSc, Christoph Lutz, Pontus Lundberg, PhD, Lothar Kanz, Leticia Quintanilla-Martinez, MD, Alexander Steinle, Andreas Trumpp, Prof, PhD, Helmut R. Salih, MD, Claudia Lengerke, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 769.
https://doi.org/10.1182/blood-2018-99-118047
Published: 2018
Journal Articles

GADD45b Plays an Essential Role in the G-CSF Triggered Granulocytic Differentiation of Human Hematopoietic Cells

Perihan Mir, Masoud Nasri, Benjamin Dannenmann, Maksim Klimiankou, Betuel Findik, Regine Bernhard, Michael A. Rieger, Cornelia Zeidler, Lothar Kanz, Karl Welte, Julia Skokowa, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 17.
https://doi.org/10.1182/blood-2018-99-114875
Published: 2018
Journal Articles

Life Expectancy in Long-Term Survivors Transplanted for Myelofibrosis: A Registry Study from the Chronic Malignancies Working Party of the European Society for Blood and Marrow Transplantation

Marie Robin, MD PhD, Diderik-Jan Eikema, Liesbeth C de Wreede, PhD, Wolschke Christine, Johannes Schetelig, MD, Maria Teresa Van Lint, MD, Dietrich W Beelen, MD PhD, Nina Simone Knelange, Arne Brecht, MD, Dietger W. Niederwieser, MD, Antonin Vitek, MDPhD, Lothar Kanz, MD, Renate Arnold, Jürgen Finke, MD, Liisa Volin, MD PhD, Ibrahim Yakoub-Agha, Arnon Nagler, MD, Hermann Einsele, Xavier Poire, Patrice Chevallier, MD, Ernst Holler, PhD, Per Ljungman, Stephen Robinson, MD PhD, Aleksandar Radujkovic, MD, Yves Chalandon, MD PhD, Kroger Nicolaus
Journal: Blood
Blood (2017) 130 (Supplement 1): 3307.
https://doi.org/10.1182/blood.V130.Suppl_1.3307.3307
Published: 2017
Journal Articles

Optimized EBMT Transplant-Specific Risk Score of Patients with Myelodysplastic Syndromes Following Allogeneic Stem Cell Transplantation

Nico Gagelmann, Matthias Stelljes, MD, Dietrich W Beelen, MD PhD, Dirk-Jan Eikema, Nina Simone Knelange, Ghulam Mufti, DM, FRCP, FRCPath, Dietger Niederwieser, MD, Henrik Sengeloev, Gerhard Ehninger, Arnon Nagler, MD, Ibrahim Yakoub-Agha, Ellen Meijer, Per Ljungman, Johan Maertens, Lothar Kanz, Lucia Lopez Corral, Arne Brecht, MD, Charles Craddock, Jürgen Finke, MD, Jan J Cornelissen, Paolo Bernasconi, Patrice Chevallier, MD, Jorge Sierra, Marie Robin, MD PhD, Nicolaus Kroeger, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3325.
https://doi.org/10.1182/blood.V130.Suppl_1.3325.3325
Published: 2017
Journal Articles

Establishment of the Safe and Efficient CRISPR/Cas9-RNP Based Gene-Correction Platform of ELANE Mutations in iPSCs of Severe Congenital Neutropenia (CN) Patients with No Response to G-CSF and High Risk to Develop Leukemia

Masoud Nasri, MSc, Benjamin Dannenmann, Perihan Mir, Tessa Skroblyn, Anna Solovjeva, Maksim Klimiankou, Cornelia Zeidler, Lothar Kanz, Karl Welte, Julia Skokowa
Journal: Blood
Blood (2017) 130 (Supplement 1): 542.
https://doi.org/10.1182/blood.V130.Suppl_1.542.542
Published: 2017