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Journal Articles

Exploiting the Metabolic Vulnerability of Leukemic Stem Cells (LSCs) in Inv(16) Acute Myeloid Leukemia (AML) with the Combination of Miristen, a Mir-126 Inhibitor, and Venetoclax

Lianjun Zhang, Dinh Hoa Hoang, Hyunjun Kang, Ying-Chieh Chen, Yu-Hsuan Fu, Khyatiben V. Pathak, Melissa Valerio, Fang Chen, Katrina Estrella, Ralf Buettner, Bin Zhang, Patrick Pirrotte, Guido Marcucci, Ya-Huei Kuo, Le Xuan Truong Nguyen
Journal: Blood
Blood (2023) 142 (Supplement 1): 2953.
https://doi.org/10.1182/blood-2023-186936
Published: 2023
Journal Articles

Acquired microRNA-142 Deficit Drives Escape Mechanisms of Anti-Leukemic Surveillance during Blast Crisis Transformation of Chronic Myeloid Leukemia (CML)

Fang Chen, Dandan Zhao, Yi Zhang, Yongfang Xu, Min-Hsuan Chen, Khyatiben V. Pathak, Yong Liang, Wei-Le Wang, Katrina Estrella, Xiwei Wu, Lucy Y. Ghoda, Ya-Huei Kuo, Haris Ali, Jianhua Yu, Michael A Caligiuri, Mark Boldin, Piotr Swiderski, Marcin Kortylewski, Patrick Pirrotte, Le Xuan Truong Nguyen, Guido Marcucci, Bin Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 3152.
https://doi.org/10.1182/blood-2023-182587
Published: 2023
Journal Articles

In Vivo Antileukemic Activity of Ost-01 in Acute Myeloid Leukemia (AML): A Novel Natural Product (NP) from Baccharis Coridifolia

Hyunjun Kang, Dinh Hoa Hoang, Melissa Valerio, Khyatiben V. Pathak, Lianjun Zhang, Ralf Buettner, Fang Chen, Katrina Estrella, William Graff, Ya-Huei Kuo, Bin Zhang, Patrick Pirrotte, Le Xuan Truong Nguyen, Guido Marcucci
Journal: Blood
Blood (2023) 142 (Supplement 1): 1565.
https://doi.org/10.1182/blood-2023-187736
Published: 2023
Journal Articles

Disruption of dNTP homeostasis by ribonucleotide reductase hyperactivation overcomes AML differentiation blockade

Hanying Wang, Xin He, Lei Zhang, Haojie Dong, Feiteng Huang, Jie Xian, Min Li, Wei Chen, Xiyuan Lu, Khyatiben V. Pathak, Wenfeng Huang, Zheng Li, Lianjun Zhang, Le Xuan Truong Nguyen, Lu Yang, Lifeng Feng, David J. Gordon, Jing Zhang, Patrick Pirrotte, Chun-Wei Chen, Amandeep Salhotra, Ya-Huei Kuo, David Horne, Guido Marcucci, David B. Sykes, Stefano Tiziani, Hongchuan Jin, Xian Wang, Ling Li
Journal: Blood
Blood (2022) 139 (26): 3752–3770.
https://doi.org/10.1182/blood.2021015108
Published: 2022
Includes: Supplemental data