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Journal Articles

A Rapid Test to Evaluate the Tumor Differentiation State of Acute Myeloid Leukemias

Stephen E. Kurtz, Christopher A. Eide, Nicola Long, Daniel Bottomly, Shannon K McWeeney, Akosha Taylor, Brian J. Druker, Sudarshan Anand, Curtis A. Lachowiez, Jeffrey W Tyner
Journal: Blood
Blood (2023) 142 (Supplement 1): 3643.
https://doi.org/10.1182/blood-2023-180105
Published: 2023
Journal Articles

Acute Myeloid Leukemia Differentiation State and Genotype Influence Anti-Apoptotic Protein Expression, Venetoclax Sensitivity, and Survival in AML

Curtis A. Lachowiez, Christopher A. Eide, Stephen E. Kurtz, Nicola Long, Manoj Rai, Wei Xie, Andy Kaempf, Daniel Bottomly, Rachel Cook, Gabrielle Meyers, Arpita Gandhi, Jessica T. Leonard, Brandon Hayes-Lattin, Laura F. Newell, Richard T Maziarz, Jennifer N. Saultz, Elie Traer, Theodore P Braun, Ronan T. Swords, Shannon K McWeeney, Jeffrey W Tyner
Journal: Blood
Blood (2023) 142 (Supplement 1): 978.
https://doi.org/10.1182/blood-2023-179527
Published: 2023
Journal Articles

Prognostic Significance of NCAM1 (CD56) Expression in AML Patients Treated with HMA+Venetoclax

Jennifer N. Saultz, Manoj Rai, Faith Burns, Daniel J Chandra, Sunil K Joshi, Curtis A. Lachowiez, Andy Kaempf, Andrew N Nemecek, Yoko Kosaka, Evan F. Lind, Stephen E. Kurtz, Nicola Long, Rachel Cook, Gabrielle Meyers, Arpita Gandhi, Jessica T. Leonard, Brandon Hayes-Lattin, Laura F. Newell, Richard T Maziarz, Elie Traer, Ronan T. Swords, Theodore P Braun, Cristina Tognon, Jeffrey W Tyner
Journal: Blood
Blood (2023) 142 (Supplement 1): 5762.
https://doi.org/10.1182/blood-2023-188311
Published: 2023
Journal Articles

Defining Clinical and Molecular Biomarkers for Venetoclax-Based Drug Combinations to Augment AML Therapy

Christopher A. Eide, Stephen E. Kurtz, Andy Kaempf, Nicola Long, Sunil K Joshi, Tamilla Nechiporuk, Ariane Huang, Charles Dibb, Daniel Bottomly, Shannon K. McWeeney, Bill H. Chang, Brian J. Druker, Jeffrey W. Tyner
Journal: Blood
Blood (2022) 140 (Supplement 1): 1025–1027.
https://doi.org/10.1182/blood-2022-159264
Published: 2022
Journal Articles

Identification and prioritization of myeloid malignancy germline variants in a large cohort of adult patients with AML

Clinical Trials & Observations
Fei Yang, Nicola Long, Tauangtham Anekpuritanang, Daniel Bottomly, Jonathan C. Savage, Tiffany Lee, Jose Solis-Ruiz, Uma Borate, Beth Wilmot, Cristina Tognon, Allison M. Bock, Daniel A. Pollyea, Saikripa Radhakrishnan, Srinidhi Radhakrishnan, Prapti Patel, Robert H. Collins, Srinivas Tantravahi, Michael W. Deininger, Guang Fan, Brian Druker, Ujwal Shinde, Jeffrey W. Tyner, Richard D. Press, Shannon McWeeney, Anupriya Agarwal
Journal: Blood
Blood (2022) 139 (8): 1208–1221.
https://doi.org/10.1182/blood.2021011354
Published: 2022
Includes: Supplemental data
Journal Articles

Associating Ex Vivo Drug Sensitivity with Differentiation Status Identifies Effective Drug Combinations for Acute Myeloid Leukemia

Christopher A. Eide, Stephen E. Kurtz, Andy Kaempf, Nicola Long, Daniel Bottomly, Olga Nikolova, Brian J. Druker, Shannon K. McWeeney, Jeffrey W. Tyner, Anupriya Agarwal
Journal: Blood
Blood (2021) 138 (Supplement 1): 1301.
https://doi.org/10.1182/blood-2021-152043
Published: 2021
Journal Articles

Patterns of Venetoclax Sensitivity in Chronic Lymphocytic Leukemia

James T Dibb, DO, Nicola Long, Christopher A. Eide, Stephen E Kurtz, PhD, Cristina E. Tognon, PhD, Jeffrey W. Tyner, PhD, Brian J. Druker, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 12–14.
https://doi.org/10.1182/blood-2020-137674
Published: 2020
Journal Articles

Framework to Identify and Prioritize Candidate Inherited Myeloid Malignancy Germline Variants Leveraging the BEAT AML Cohort

Daniel Bottomly, Nicola Long, Fei Yang, MD, Tiffany Lee, MD, Uma Borate, MD, Beth Wilmot, PhD, Adam S DuVall, MD, Andrea Monteblanco, BS, Karina Thiel-Klare, Gabby Dewson, BA, Richard D. Press, MD PhD, Cristina E. Tognon, Brian J. Druker, Jeffrey W. Tyner, Shannon K. McWeeney, PhD, Anupriya Agarwal, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1407.
https://doi.org/10.1182/blood-2019-132224
Published: 2019
Journal Articles

Simultaneous Kinase Inhibition with Ibrutinib and BCL2 Inhibition with Venetoclax As a Therapeutic Strategy for Acute Lymphoblastic Leukemia

Christopher A. Eide, Stephen E Kurtz, PhD, Andy Kaempf, MS, Nicola Long, Jessica Leonard, MD, Bill H. Chang, MD PhD, Motomi Mori, PhD, Brian J. Druker, Jeffrey W. Tyner
Journal: Blood
Blood (2019) 134 (Supplement_1): 3950.
https://doi.org/10.1182/blood-2019-131288
Published: 2019
Journal Articles

Patterns of Sensitivity Exhibited By Venetoclax-Inclusive Drug Combinations in Acute Myeloid Leukemia

Stephen E Kurtz, PhD, Christopher A. Eide, Andy Kaempf, MS, Nicola Long, Anupriya Agarwal, PhD, Cristina E. Tognon, Motomi Mori, PhD, Brian J. Druker, Jeffrey W. Tyner
Journal: Blood
Blood (2019) 134 (Supplement_1): 878.
https://doi.org/10.1182/blood-2019-126020
Published: 2019
Journal Articles

Genomic landscape of neutrophilic leukemias of ambiguous diagnosis

Haijiao Zhang, Beth Wilmot, Daniel Bottomly, Kim-Hien T. Dao, Emily Stevens, Christopher A. Eide, Vishesh Khanna, Angela Rofelty, Samantha Savage, Anna Reister Schultz, Nicola Long, Libbey White, Amy Carlos, Rachel Henson, Chenwei Lin, Robert Searles, Robert H. Collins, Daniel J. DeAngelo, Michael W. Deininger, Tamara Dunn, Than Hein, Marlise R. Luskin, Bruno C. Medeiros, Stephen T. Oh, Daniel A. Pollyea, David P. Steensma, Richard M. Stone, Brian J. Druker, Shannon K. McWeeney, Julia E. Maxson, Jason R. Gotlib, Jeffrey W. Tyner
Journal: Blood
Blood (2019) 134 (11): 867–879.
https://doi.org/10.1182/blood.2019000611
Published: 2019
Includes: Supplemental data
Journal Articles

CSF1R inhibitors exhibit antitumor activity in acute myeloid leukemia by blocking paracrine signals from support cells

David K. Edwards, V, Kevin Watanabe-Smith, Angela Rofelty, Alisa Damnernsawad, Ted Laderas, Adam Lamble, Evan F. Lind, Andy Kaempf, Motomi Mori, Mara Rosenberg, Amanda d’Almeida, Nicola Long, Anupriya Agarwal, David Tyler Sweeney, Marc Loriaux, Shannon K. McWeeney, Jeffrey W. Tyner
Journal: Blood
Blood (2019) 133 (6): 588–599.
https://doi.org/10.1182/blood-2018-03-838946
Published: 2019
Includes: Supplemental data