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Journal Articles

The TLK-ASF1 histone chaperone pathway plays a critical role in IL-1β–mediated AML progression

Hsin-Yun Lin, Mona Mohammadhosseini, John McClatchy, Marina Villamor-Payà, Sophia Jeng, Daniel Bottomly, Chia-Feng Tsai, Camilo Posso, Jeremy Jacobson, Andrew Adey, Sara Gosline, Tao Liu, Shannon McWeeney, Travis H. Stracker, Anupriya Agarwal

Blood (2024) 143 (26): 2749–2762.

https://doi.org/10.1182/blood.2023022079

Published: 2024

Includes: Supplemental data

Journal Articles

Identification and prioritization of myeloid malignancy germline variants in a large cohort of adult patients with AML

Blood (2022) 139 (8): 1208–1221.

https://doi.org/10.1182/blood.2021011354

Published: 2022

Includes: Supplemental data

Journal Articles

Identification of Effective Combinations of Targeted Drugs for DNMT3A and NPM1 Mutated Acute Myeloid Leukemia

Stephen E Kurtz, PhD, Christopher A. Eide, Andy Kaempf, Samantha L Savage, Anna M. Reister Schultz, Beth Wilmot, PhD, Shannon Mcweeney, PhD, Motomi Mori, PhD, Elie Traer, MD PhD, Brian J. Druker, MD, Jeffrey W. Tyner, PhD

Blood (2017) 130 (Supplement 1): 2068.

https://doi.org/10.1182/blood.V130.Suppl_1.2068.2068

Published: 2017

Journal Articles

Therapeutically Targetable Activating c-ABL1 Mutations in Philadelphia Chromosome-Negative Leukemias

Samantha L Savage, Julia E. Maxson, PhD, Christopher A. Eide, Chelsea Jenkins, B.S., Melissa L Abel, Anna M. Reister Schultz, Daniel Bottomly, Beth Wilmot, PhD, Shannon Mcweeney, PhD, Cristina E. Tognon, PhD, Jeffrey W. Tyner, PhD, Brian J. Druker, MD

Blood (2017) 130 (Supplement 1): 3930.

https://doi.org/10.1182/blood.V130.Suppl_1.3930.3930

Published: 2017

Journal Articles

CG '806, a First-in-Class Pan-FLT3/BTK Inhibitor, Exhibits Potent Growth Inhibition As a Single Agent and in Combination with a BET Bromodomain Inhibitor or a Bcl2 Inhibitor on Primary AML and CLL Patient Samples

Stephen E Kurtz, PhD, Beth Wilmot, PhD, Shannon Mcweeney, PhD, Andrea Local, PhD, Hongying Zhang, MD, Stephen Howell, MD, William Rice, PhD, Brian J. Druker, MD, Jeffrey W. Tyner, PhD

Blood (2017) 130 (Supplement 1): 4626.

https://doi.org/10.1182/blood.V130.Suppl_1.4626.4626

Published: 2017

Journal Articles

Coexisting Oncogenic Signaling Pathway Mutations in Cnl/Acml/CMML/MPN-U

Haijiao Zhang, Daniel Bottomly, Libbey K. White, Beth Wilmot, PhD, Shannon Mcweeney, PhD, Jeffrey W. Tyner, PhD

Blood (2017) 130 (Supplement 1): 4213.

https://doi.org/10.1182/blood.V130.Suppl_1.4213.4213

Published: 2017

Journal Articles

Definition of the Minimal Truncated Elements Necessary for CSF3R Leukemogenic Potential

Haijiao Zhang, MD, Anna Reister Schultz, B.S., Samuel B Luty, BS, Sophie Means, B.S., Larry David, PhD, John Klimek, B.S., Daniel Bottomly, Beth Wilmot, Shannon McWeeney, PhD, Yulong Su, B.S., Jeffrey W. Tyner

Blood (2016) 128 (22): 2735.

https://doi.org/10.1182/blood.V128.22.2735.2735

Published: 2016

Journal Articles

BCR-ABL1 promotes leukemia by converting p27 into a cytoplasmic oncoprotein

Anupriya Agarwal, Ryan J. Mackenzie, Arnaud Besson, Sophia Jeng, Alyssa Carey, Dorian H. LaTocha, Angela G. Fleischman, Nicolas Duquesnes, Christopher A. Eide, Kavin B. Vasudevan, Marc M. Loriaux, Eduardo Firpo, Jorge E. Cortes, Shannon McWeeney, Thomas O’Hare, James M. Roberts, Brian J. Druker, Michael W. Deininger

Blood (2014) 124 (22): 3260–3273.

https://doi.org/10.1182/blood-2013-04-497040

Published: 2014

Includes: Supplemental data

Journal Articles

A Truncation Mutant of CSF3R, Identified As a Novel Driver in De Novo Myeloid Leukemia, Signals Through TNK2, and Is Responsive to Dasatinib.

Julia E Maxson, PhD, Jason Gotlib, Angela G. Fleischman, MD, PhD, Christopher A. Eide, Daniel Bottomly, MS, Beth Wilmot, PhD, MS, Shannon McWeeney, PhD, Cristina Tognon, PhD, Marc M Loriaux, MD, PhD, Brian J. Druker, Jeffrey W Tyner, PhD

Blood (2012) 120 (21): 2412.

https://doi.org/10.1182/blood.V120.21.2412.2412

Published: 2012

Journal Articles

A Gene Expression Signature of CD34+ Cells to Predict Major Cytogenetic Response in Chronic Phase Chronic Myeloid Leukemia Patients Treated with Imatinib: Potential Involvement of Beta-Catenin in Drug Resistance.

Shannon McWeeney, Gregory Yochum, Lucy C. Pemberton, MD, FRCPath, Marc Loriaux, MD, PhD, Kristina Vartanian, Stephanie G Willis, Beth Wilmot, Yaron Turpaz, Raji Pillai, Mary Mac partlin, Jennifer Snead, PhD, Brian J. Druker, MD, Stephen G O'Brien, MD, PhD, Junia V. Melo, MD, PhD, Thoralf Lange, MD, Christina Harrington, Michael Deininger, MD, PhD

Blood (2009) 114 (22): 508.

https://doi.org/10.1182/blood.V114.22.508.508

Published: 2009

Journal Articles

Comparative Functional Genomic Analysis of Myelodysplasia (MDS) in Fanconi Anemia (FA).

Grover C. Bagby, MD, Shannon McWeeney, PhD, Jane Yates, Byung Park, PhD, R. Keaney Rathbun, Daniela Pilonetto, PhD, Richard Harris, MD, John Wagner, MD, Christina Harrington, PhD, Motomi Mori, PhD, Ricardo Pasquini, MD, D. Wade Clapp, MD

Blood (2006) 108 (11): 2636.

https://doi.org/10.1182/blood.V108.11.2636.2636

Published: 2006

Journal Articles

Cerebrospinal Fluid (CSF) Proteomics in Children with Acute Lymphoblastic Leukemia (ALL).

Robert C. Trueworthy, MD, Linda Stork, MD, Yanping Zhong, MD, Sharon Pine, PhD, Yousif Matloub, MD, Ted Laderas, MS, Shannon McWeeney, PhD, Guang Fan, MD, PhD

Blood (2006) 108 (11): 1834.

https://doi.org/10.1182/blood.V108.11.1834.1834

Published: 2006

Journal Articles

High-sensitivity detection of BCR-ABL kinase domain mutations in imatinib-naive patients: correlation with clonal cytogenetic evolution but not response to therapy

Stephanie G. Willis, Thoralf Lange, Shadmehr Demehri, Sandra Otto, Lucy Crossman, Dietger Niederwieser, Eric P. Stoffregen, Shannon McWeeney, Ines Kovacs, Byung Park, Brian J. Druker, Michael W. Deininger

Blood (2005) 106 (6): 2128–2137.

https://doi.org/10.1182/blood-2005-03-1036

Published: 2005

Journal Articles

Detection of Imatinib-Resistant BCR-ABL Mutants in Drug-Naïve Patients: Correlation with Disease Phase and Clonal Evolution but Not with Response to Treatment.

Michael W. Deininger, MD, PhD, Stephanie Willis, Thoralf Lange, MD, Shannon McWeeney, PhD, Sandra Otto, Brian J. Druker, MD

Blood (2004) 104 (11): 273.

https://doi.org/10.1182/blood.V104.11.273.273

Published: 2004

Journal Articles

Clonal Evolution of Fanconi Anemia (FA) Stem Cells Results from Clonal Adaptation and Clonal Selection. A Report from the International Fanconi Anemia Transcriptome Consortium.

Grover Bagby, MD, Jane Yates, Shannon McWeeney, PhD, Byung Park, MS, Keaney Rathbun, Daniela Pilonetto, PhD, Richard Harris, MD, John Wagner, MD, Gerard Pals, PhD, See Yan Lau, MS, Christina Harrington, PhD, Motomi Mori, PhD, Ricardo Pasquini, MD

Blood (2004) 104 (11): 3416.

https://doi.org/10.1182/blood.V104.11.3416.3416

Published: 2004

NARROW

The TLK-ASF1 histone chaperone pathway plays a critical role in IL-1β–mediated AML progression

Identification and prioritization of myeloid malignancy germline variants in a large cohort of adult patients with AML

Identification of Effective Combinations of Targeted Drugs for DNMT3A and NPM1 Mutated Acute Myeloid Leukemia

Therapeutically Targetable Activating c-ABL1 Mutations in Philadelphia Chromosome-Negative Leukemias

CG '806, a First-in-Class Pan-FLT3/BTK Inhibitor, Exhibits Potent Growth Inhibition As a Single Agent and in Combination with a BET Bromodomain Inhibitor or a Bcl2 Inhibitor on Primary AML and CLL Patient Samples

Coexisting Oncogenic Signaling Pathway Mutations in Cnl/Acml/CMML/MPN-U

Definition of the Minimal Truncated Elements Necessary for CSF3R Leukemogenic Potential

BCR-ABL1 promotes leukemia by converting p27 into a cytoplasmic oncoprotein

A Truncation Mutant of CSF3R, Identified As a Novel Driver in De Novo Myeloid Leukemia, Signals Through TNK2, and Is Responsive to Dasatinib.

A Gene Expression Signature of CD34+ Cells to Predict Major Cytogenetic Response in Chronic Phase Chronic Myeloid Leukemia Patients Treated with Imatinib: Potential Involvement of Beta-Catenin in Drug Resistance.

Comparative Functional Genomic Analysis of Myelodysplasia (MDS) in Fanconi Anemia (FA).

Cerebrospinal Fluid (CSF) Proteomics in Children with Acute Lymphoblastic Leukemia (ALL).

High-sensitivity detection of BCR-ABL kinase domain mutations in imatinib-naive patients: correlation with clonal cytogenetic evolution but not response to therapy

Detection of Imatinib-Resistant BCR-ABL Mutants in Drug-Naïve Patients: Correlation with Disease Phase and Clonal Evolution but Not with Response to Treatment.

Clonal Evolution of Fanconi Anemia (FA) Stem Cells Results from Clonal Adaptation and Clonal Selection. A Report from the International Fanconi Anemia Transcriptome Consortium.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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