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Journal Articles

Novel MAGIC composite scores using both clinical symptoms and biomarkers best predict treatment outcomes of acute GVHD

Clinical Trials & Observations
Yu Akahoshi, Nikolaos Spyrou, Daniela Weber, Paibel Aguayo-Hiraldo, Francis Ayuk, Chantiya Chanswangphuwana, Hannah K. Choe, Matthias Eder, Aaron M. Etra, Stephan A. Grupp, Elizabeth O. Hexner, William J. Hogan, Carrie L. Kitko, Sabrina Kraus, Monzr M. Al Malki, Pietro Merli, Muna Qayed, Ran Reshef, Tal Schechter, Evelyn Ullrich, Ingrid Vasova, Matthias Wölfl, Robert Zeiser, Janna Baez, Rahnuma Beheshti, Gilbert Eng, Sigrun Gleich, Nikolaos Katsivelos, Steven Kowalyk, George Morales, Rachel Young, Yi-Bin Chen, Ryotaro Nakamura, John E. Levine, James L. M. Ferrara
Journal: Blood
Blood (2024) 144 (9): 1010–1021.
https://doi.org/10.1182/blood.2024025106
Published: 2024
Includes: Supplemental data
Journal Articles

MRD at the end of induction and EFS in T-cell lymphoblastic lymphoma: Children’s Oncology Group trial AALL1231

CME Clinical Trials & Observations Brief Report
Robert J. Hayashi, Michelle L. Hermiston, Brent L. Wood, David T. Teachey, Meenakshi Devidas, Zhiguo Chen, Robert D. Annett, Barbara L. Asselin, Keith August, Steve Cho, Kimberly P. Dunsmore, Jason Lawrence Freedman, Paul J. Galardy, Paul Harker-Murray, Terzah M. Horton, Alok Jaju, Allison Lam, Yoav H. Messinger, Rodney R. Miles, Maki Okada, Samir Patel, Eric S. Schafer, Tal Schechter, Kristin A. Shimano, Neelam Singh, Amii Steele, Maria L. Sulis, Sarah L. Vargas, Stuart S. Winter, Charlotte Wood, Patrick A. Zweidler-McKay, Mignon L. Loh, Stephen P. Hunger, Elizabeth A. Raetz, Catherine M. Bollard, Carl E. Allen
Journal: Blood
Blood (2024) 143 (20): 2053–2058.
https://doi.org/10.1182/blood.2023021184
Published: 2024
Includes: Supplemental data
Journal Articles

A Day 14 Endpoint for Acute Gvhd Clinical Trials

Nikolaos Spyrou, Yu Akahoshi, Steven Kowalyk, George Morales, Rahnuma Beheshti, Paibel Aguayo-Hiraldo, MHD Monzr Al Malki, Francis Ayuketang Ayuk, Peter Bader, Janna Baez, Alexandra Capellini, Hannah Choe, Zachariah Defilipp, Matthias Eder, Gilbert Eng, Aaron Etra, Sigrun Gleich, Stephan Grupp, Elizabeth Hexner, Matthias Hoepting, William J. Hogan, Stelios Kasikis, Nikolaos Katsivelos, Carrie L. Kitko, Sabrina Kraus, Deukwoo Kwon, Pietro Merli, Joseph Portelli, Muna Qayed, Ran Reshef, Tal Schechter-Finkelstein, Ingrid Vasova, Matthias Woelfl, Kitsada Wudhikarn, Rachel Young, Ernst Holler, Yi-Bin Chen, Ryotaro Nakamura, John Levine, James L.M. Ferrara
Journal: Blood
Blood (2023) 142 (Supplement 1): 779.
https://doi.org/10.1182/blood-2023-172955
Published: 2023
Journal Articles

Flares of Acute Graft-Versus-Host Disease: Mount Sinai Acute Gvhd International Consortium (MAGIC) Study

Yu Akahoshi, Nikolaos Spyrou, Daniela Weber, Paibel Aguayo-Hiraldo, Francis A. Ayuk, Udomsak Bunworasate, Hannah Choe, Matthias Eder, Aaron Etra, Stephan Grupp, Elizabeth O Hexner, William J. Hogan, Carrie L. Kitko, Sabrina Kraus, Pietro Merli, Muna Qayed, Ran Reshef, Tal Schechter-Finkelstein, Evelyn Ullrich, Ingrid Vasova, Matthias Woelfl, Robert Zeiser, Janna Baez, Rahnuma Beheshti, Sigrun Gleich, Nikolaos Katsivelos, Steven Kowalyk, George Morales, Rachel Young, Yi-Bin Chen, James L.M. Ferrara, John Levine, Ryotaro Nakamura
Journal: Blood
Blood (2023) 142 (Supplement 1): 776.
https://doi.org/10.1182/blood-2023-181900
Published: 2023
Journal Articles

Correlation of Minimal Residual Disease (MRD) at the End of Induction (EOI) and Event Free Survival (EFS) in T-Cell Lymphoblastic Lymphoma (T-LL), a Report from the Children's Oncology Group (COG) Trial AALL1231

Robert J. Hayashi, Michelle L. Hermiston, David T. Teachey, Meenakshi Devidas, Brent L. Wood, Zhiguo Chen, Robert D Annett, Barbara L Asselin, Keith J August, Steve Y Cho, Kimberly P. Dunsmore, Jason L. Freedman, Paul J. Galardy, Paul Harker-Murray, Terzah M. Horton, Alok I Jaju, Allison Lam, Yoav H. Messinger, Rodney R. Miles, Maki Okada, Samir I Patel, Eric S Schafer, Tal Schechter-Finkelstein, Kristin A. Shimano, Neelam Singh, Amii C. Steele, Maria Luisa Sulis, Sarah L Vargas, Stuart S. Winter, Charlotte Wood, Patrick A Zweidler-McKay, Mignon L. Loh, Stephen P. Hunger, Elizabeth A. Raetz, Catherine M Bollard, Carl Allen
Journal: Blood
Blood (2022) 140 (Supplement 1): 6387–6389.
https://doi.org/10.1182/blood-2022-159694
Published: 2022
Journal Articles

Metabolomic identification of α-ketoglutaric acid elevation in pediatric chronic graft-versus-host disease

Clinical Trials & Observations
Divya Subburaj, Bernard Ng, Amina Kariminia, Sayeh Abdossamadi, Madeline Lauener, Eneida R. Nemecek, Jacob Rozmus, Sandhya Kharbanda, Carrie L. Kitko, Victor A. Lewis, Tal Schechter-Finklestein, David A. Jacobsohn, Andrew C. Harris, Michael A. Pulsipher, Henrique Bittencourt, Sung Won Choi, Emi H. Caywood, Kimberly A. Kasow, Monica Bhatia, Benjamin R. Oshrine, Donald Coulter, Joseph H. Chewning, Michael Joyce, Anna B. Pawlowska, Gail C. Megason, Anita Lawitschka, Elena Ostroumov, Ramon Klein Geltink, Geoffrey D. E. Cuvelier, Kirk R. Schultz
Journal: Blood
Blood (2022) 139 (2): 287–299.
https://doi.org/10.1182/blood.2021013244
Published: 2022
Includes: Supplemental data
Journal Articles

Prognostic Value of Elafin in Acute Graft-Versus-Host Disease

Makda Getachew Zewde, George Morales, Isha Gandhi, Umut Ozbek, Paibel Aguayo-Hiraldo, Francis A. Ayuk, Janna Baez, Chantiya Chanswangphuwana, Hannah Choe, Zachariah DeFilipp, Aaron Etra, Stephan A. Grupp, Elizabeth O. Hexner, William J Hogan, Rebeka Javorniczky, Stelios Kasikis, Carrie Lynn Kitko, Steven Kowalyk, Elisabeth Meedt, Pietro Merli, Ryotaro Nakamura, Muna Qayed, Ran Reshef, Wolf Roesler, Tal Schechter-Finkelstein, Daniela Weber, Matthias Wölfl, Gregory A Yanik, Rachel Young, John E. Levine, James L. Ferrara, Yi-Bin Chen
Journal: Blood
Blood (2021) 138 (Supplement 1): 3900.
https://doi.org/10.1182/blood-2021-154302
Published: 2021
Journal Articles

Intensification of Chemotherapy Using a Modified BFM Backbone for Children, Adolescents and Young Adults with T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL) Identifies Highly Chemorefractory Patients Who Benefit from Allogeneic Hematopoietic Stem Cell Transplantation

Paul Harker-Murray, Brent L. Wood, Meenakshi Devidas, Zhiguo Chen, Tal Schechter-Finkelstein, Robert J. Hayashi, Keith J August, Kimberly P. Dunsmore, Michelle L. Hermiston, Terzah M. Horton, Yoav H. Messinger, Sarah L Vargas, Eric S Schafer, Maria Luisa Sulis, Stuart S. Winter, Charlotte Wood, Catherine M Bollard, Mignon L. Loh, Stephen P Hunger, Elizabeth A. Raetz, David T. Teachey
Journal: Blood
Blood (2021) 138 (Supplement 1): 3487.
https://doi.org/10.1182/blood-2021-151837
Published: 2021
Journal Articles

Peripheral Venous Access for Collection of Immune Effector Cells and Hematopoietic Stem Cells Is Feasible and Safe in Older Children and Young Adult Patients

Joel Livingston, MDMSc, Maria Di-Mola, RN, Jane Lowry, RN, Nigel Ruse, RN, Christoph Licht, MDFRCP, Muhammad Ali, Tal Schechter-Finkelstein, MD, KY Chiang, Joerg Krueger, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 19–20.
https://doi.org/10.1182/blood-2020-137747
Published: 2020
Journal Articles

TINF2 Mutations Are Associated with Poor Outcome Post Hematopoietic Stem Cell Transplantation for Dyskeratosis Congenita

Yeon Jung Lim, MD, Omri Avraham Arbiv, Melanie Evelyn Kalbfleisch, Mohammed Nuaimi, MD, MacGregor Steele, MD FRCPC, Geoff D.E. Cuvelier, MD, Tal Schechter-Finkelstein, MD, Bozana Zlateska, MD MSc, Michaela Cada, MD FRCPC, FAAP, MPH, Yigal Dror, MD FRCPC
Journal: Blood
Blood (2020) 136 (Supplement 1): 26.
https://doi.org/10.1182/blood-2020-142447
Published: 2020
Journal Articles

Naïve Helper T-Cell and Regulatory T- and NK-Cell Subsets Are Associated with Pediatric Chronic Graft-Versus-Host Disease: Results of the ABLE / PBMTC 1202 Study

Geoff D.E. Cuvelier, MD, Amina Kariminia, PhD, Eneida R. Nemecek, MDMBA,MSc, Carrie Kitko, MD, Justin T. Wahlstrom, MD, Andrew C Harris, MD, Henrique Bittencourt, MD PhD, Victor A. Lewis, MD, Michael A Pulsipher, MD, Tal Schechter-Finkelstein, MD, Sung W. Choi, MD, Emi Caywood, MD, Monica Bhatia, MD, Kimberly A. Kasow, DO, David Jacobsohn, MD, Benjamin Oshrine, MD, Sonali Chaudhury, MD, Joseph H. Chewning, MD, Flower Allyson, MD, Don W. Coulter, MD, Michael J. Joyce, MD, Sureyya Savasan, MD, Anna Pawlowska, MD, Gail Megason, MD, David Mitchell, MD, Alexandra Cheerva, MD, Anita Lawitschka, MD, Bernard Ng, PhD, Kirk R. Schultz, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11–12.
https://doi.org/10.1182/blood-2020-139031
Published: 2020
Journal Articles

Cranial Radiation Can be Eliminated in Most Children with T-Cell Acute Lymphoblastic Leukemia (T-ALL) and Bortezomib Potentially Improves Survival in Children with T-Cell Lymphoblastic Lymphoma (T-LL): Results of Children's Oncology Group (COG) Trial AALL1231

David T. Teachey, MD, Meenakshi Devidas, PhD, Brent L Wood, MD PhD, Zhiguo Chen, MS, Robert James Hayashi, MD, Robert D Annett, PhD, Barbara L Asselin, MD, Keith J August, MDMS, Steve Y Cho, MD, Kimberly P. Dunsmore, MD, Brian T. Fisher, DO, MSCE, Jason L. Freedman, MD, Paul J. Galardy, MD, Paul Harker-Murray, MD PhD, Michelle L. Hermiston, MD PhD, Terzah M Horton, MD PhD, Alok I Jaju, MD, Allison Lam, BCPS, Yoav H. Messinger, MD, Rodney R. Miles, MD PhD, Maki Okada, RN, Samir I Patel, MD, Eric S. Schafer, MD MHS, Tal Schechter-Finkelstein, MD, Kristin A. Shimano, MD, Neelam Singh, PhD, Amii C. Steele, PhD, Maria L. Sulis, MD, Sarah L Vargas, PhD, Stuart S. Winter, MD, Charlotte Wood, CCRP, Patrick Zweider McKay, MDPhD, Catherine M. Bollard, MD MBChB, Mignon L. Loh, MD, Stephen P. Hunger, MD, Elizabeth A. Raetz, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11–12.
https://doi.org/10.1182/blood-2020-134730
Published: 2020
Journal Articles

Immune profile differences between chronic GVHD and late acute GVHD: results of the ABLE/PBMTC 1202 studies

Clinical Trials & Observations
Kirk R. Schultz, Amina Kariminia, Bernard Ng, Sayeh Abdossamadi, Madeline Lauener, Eneida R. Nemecek, Justin T. Wahlstrom, Carrie L. Kitko, Victor A. Lewis, Tal Schechter, David A. Jacobsohn, Andrew C. Harris, Michael A. Pulsipher, Henrique Bittencourt, Sung Won Choi, Emi H. Caywood, Kimberly A. Kasow, Monica Bhatia, Benjamin R. Oshrine, Allyson Flower, Sonali Chaudhury, Donald Coulter, Joseph H. Chewning, Michael Joyce, Sureyya Savasan, Anna B. Pawlowska, Gail C. Megason, David Mitchell, Alexandra C. Cheerva, Anita Lawitschka, Shima Azadpour, Elena Ostroumov, Peter Subrt, Anat Halevy, Sara Mostafavi, Geoffrey D. E. Cuvelier
Journal: Blood
Blood (2020) 135 (15): 1287–1298.
https://doi.org/10.1182/blood.2019003186
Published: 2020
Includes: Supplemental data
Journal Articles

The MAGIC Algorithm Probability (MAP): A Novel Laboratory Biomarker for the Response to Treatment of Acute Graft-Versus-Host Disease

Hrishikesh Srinagesh, BA, Umut Ozbek, PhD, Urvi Kapoor, MD, Francis Ayuketang Ayuk, MD, Mina D. Aziz, MD, Kaitlyn Ben-David, Hannah K. Choe, MD, Zachariah Defilipp, MD, Aaron Etra, MD, Stephan Grupp, MD PhD, Matthew Hartwell, MD, Elizabeth O. Hexner, MDMS, William J Hogan, MB, BCh, Carrie Kitko, MD, Steven Kowalyk, Jung-Yi Lin, MS, Hannah Major-Monfried, MD MSCR, Stephan Mielke, MD, Pietro Merli, MD, George Morales, Rainer Ordemann, MD, Michael A. Pulsipher, MD, Muna Qayed, MD MSc, Pavan Reddy, Ran Reshef, MD MSc, Wolf Roesler, MD, Karamjeet S. Sandhu, MD, Tal Schechter-Finkelstein, MD, Jay Shah, MD, Keith Sigel, MD PhD, Daniela Weber, MD, Matthias Wölfl, MD, Kitsada Wudhikarn, MD, Rachel Young, John E. Levine, MDMS, James L. M. Ferrara, MDDSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 367.
https://doi.org/10.1182/blood-2019-122011
Published: 2019
Journal Articles

The Impact of Identifying the Syndromic and Genetic Diagnoses on Hematopoietic Stem Cell Transplantation Outcome in Patients with Inherited Bone Marrow Failure Syndromes

Yeon Jung Lim, MD, Omri Avraham Arbiv, BSc, Melanie Evelyn Kalbfleisch, BSc, Robert J Klaassen, MD FRCPC, Conrad Fernandez, FRCPC, MD BSc, Meera Rayar, MacGregor Steele, MD, Jeffrey H. Lipton, MD PhD, Geoffrey Cuvelier, MD, Yves D. Pastore, MD, Mariana Silva, MD FRCPC, Josee Brossard, MD, Bruno Michon, MD FRCPC, Sharon Abish, MD, Roona Sinha, MD, Mark J. Belletrutti, MD MSc, Vicky R. Breakey, BSc,MDFRCPC, Lawrence Jardine, MD BA, FRCPC, Lisa Goodyear, MD FRCPC, Lillian Sung, MD PhD, Tal Schechter-Finkelstein, MD, Bozana Zlateska, Michaela Cada, MD FRCPC, FAAP, MPH, Yigal Dror, MDFRCPC
Journal: Blood
Blood (2019) 134 (Supplement_1): 5015.
https://doi.org/10.1182/blood-2019-121743
Published: 2019
Journal Articles

Benefits and challenges with diagnosing chronic and late acute GVHD in children using the NIH consensus criteria

CME
Geoffrey D. E. Cuvelier, Eneida R. Nemecek, Justin T. Wahlstrom, Carrie L. Kitko, Victor A. Lewis, Tal Schechter, David A. Jacobsohn, Andrew C. Harris, Michael A. Pulsipher, Henrique Bittencourt, Sung Won Choi, Emi H. Caywood, Kimberly A. Kasow, Monica Bhatia, Benjamin R. Oshrine, Allyson Flower, Sonali Chaudhury, Donald Coulter, Joseph H. Chewning, Michael Joyce, Süreyya Savaşan, Anna B. Pawlowska, Gail C. Megason, David Mitchell, Alexandra C. Cheerva, Anita Lawitschka, Lori J. West, Bo Pan, Yazid N. Al Hamarneh, Anat Halevy, Kirk R. Schultz
Journal: Blood
Blood (2019) 134 (3): 304–316.
https://doi.org/10.1182/blood.2019000216
Published: 2019
Includes: Supplemental data
Journal Articles

Serial Biomarker Monitoring Early after HCT Identifies Different Risks for Relapse and Graft-Vs-Host Disease

Mina D. Aziz, BA, Jay Shah, MD, Urvi Kapoor, MD, Christina N. Dimopoulos, Francis A. Ayuk, MD, William J. Hogan, MBBCh, Elisabeth Schreiner, MD, Hannah K. Choe, MD, Yi-Bin Chen, MD, Elizabeth O. Hexner, MDMS, Aaron Etra, MD, Pietro Merli, MD, Wolf Roesler, MD, Carrie Kitko, MD, Muna Qayed, MD MSc, Matthias Wölfl, MD, Stephan Mielke, MD, Kitsada Wudhikarn, MD, Ryotaro Nakamura, MD, Rainer Ordemann, MD, Michael A. Pulsipher, MD, Ran Reshef, MDMSc, Sarah Anand, MD, Gregory Yanik, MD, George Morales, Steven Kowalyk, Rachel Young, Nicolaus Kroeger, MD, Tal Schechter-Finkelstein, MD, Matthew Hartwell, MD, Stephanie Gergoudis, Allan Augustine, Umut Ozbek, PhD, John E. Levine, MDMS, James L.M. Ferrara, MDDSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 356.
https://doi.org/10.1182/blood-2018-99-111200
Published: 2018
Journal Articles

Functional GSTA1 Haplotypes Affect Clearance and Toxicity of Busulfan When Administered in 16 Doses to Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation: A Multicenter Prospective Study on Behalf of the Pediatric Disease Working Party of the European Society for Blood and Marrow Transplantation (EBMT)

Marc Ansari, MD, Patricia Huezo-Diaz, PhD, Chakradhara Rao Satyanarayana Uppugunduri, PhD, Tiago Nava, MD, Mohammed Aziz Rezgui, MSc, Vid Mlakar, PhD, Laurence Lesne, MSc, Yves Theoret, PhD, Yves Chalandon, MD, L Lee Dupuis, PhD, Tal Schechter, MD, Imke H Bartelink, PhD, Jaap Jan Boelens, MD PhD, R.G.M. Bredius, MD, Jean-Hugues Dalle, MD PhD Prof., Saba Azarnoush, MD, Petr Sedlacek, MD PhD, Victor A. Lewis, MD, Martin Champagne, MD, Christina Peters, MD, Henrique Bittencourt, MD PhD, Maja Krajinovic, MDPhD
Journal: Blood
Blood (2016) 128 (22): 665.
https://doi.org/10.1182/blood.V128.22.665.665
Published: 2016
Journal Articles

Guidelines for the Standardization of Acute Graft-Versus-Host Disease Clinical Data Collection: An International Consensus Report

Andrew C. Harris, MD, Rachel Young, Steven M. Devine, MD, William J Hogan, MBChB, Francis Ayuk, MD, Udomsak Bunworasate, Chantiya Chanswangphuwana, MD, Yvonne A Efebera, MD, Ernst Holler, MD PhD, Mark R Litzow, MD, Rainer Ordemann, MD, Muna Qayed, MD MSc, Anne S. Renteria, MD, Ran Reshef, MD, Matthias Wölfl, MD, Yi-Bin Chen, MD, Steven Goldstein, MD, Madan H. Jagasia, Franco Locatelli, MD PhD, Stephan Mielke, MD, David L Porter, MD, Tal Schechter, MD, Zhanna Shekhovtsova, MD, James L.M. Ferrara, MD DSc, John E. Levine, MD MS
Journal: Blood
Blood (2015) 126 (23): 3154.
https://doi.org/10.1182/blood.V126.23.3154.3154
Published: 2015
Journal Articles

Genetic Determinants of Busulfan Clearance and Outcomes in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation- Result of a Multicentric Prospective Study on Behalf of the Pediatric Disease Working Party of the European Blood and Marrow Transplantation Group

Marc Ansari, MD, M A Rezgui, Chakradhara Rao S Uppugunduri, Yves Théoret, Yves Chalandon, LL Dupuis, Tal Schechter, MD, IH Bartelink, Jaap Jan Boelens, MDPhD, Jean-Hugues Dalle, MD PhD, Saba Azarnoush, Petr Sedlacek, Prof., MD PhD, Victor A. Lewis, MD, S Mezziani, M-F Vachon, Michel Duval, MD, Martin A. Champagne, MD FRCPC, Christina Peters, MD, Henrique Bittencourt, MD, Maja Krajinovic
Journal: Blood
Blood (2014) 124 (21): 424.
https://doi.org/10.1182/blood.V124.21.424.424
Published: 2014