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Journal Articles

A phase 2 trial of CD24Fc for prevention of graft-versus-host disease

Clinical Trials & Observations
John Magenau, Samantha Jaglowski, Joseph Uberti, Sherif S. Farag, Mary Mansour Riwes, Attaphol Pawarode, Sarah Anand, Monalisa Ghosh, John Maciejewski, Thomas Braun, Martin Devenport, Susan Lu, Bhramori Banerjee, Carolyn DaSilva, Steven Devine, Mei-Jie Zhang, Linda J. Burns, Yang Liu, Pan Zheng, Pavan Reddy
Journal: Blood
Blood (2024) 143 (1): 21–31.
https://doi.org/10.1182/blood.2023020250
Published: 2024
Includes: Supplemental data
Journal Articles

Inflammatory Memory Restrains Intestinal Stem Cell (ISC) Regeneration after Allogeneic Stem Cell Transplantation (SCT)

Dongchang Zhao, Visweswaran Ravikumar, Emma Lauder, Lu Li, Yaping Sun, Katherine Oravecz-Wilson, Michael Brooks, Evan Keller, Fengju Chen, Laure Maneix, Ana Santibanez, Chad Creighton, Arvind Rao, Pavan Reddy
Journal: Blood
Blood (2023) 142 (Supplement 1): 347.
https://doi.org/10.1182/blood-2023-187189
Published: 2023
Journal Articles

Intestinal Geographical Pattern of Gut Microbiome and Metabolites Identifies Novel Regulators of Graft-Versus-Host Disease

Emma Lauder, Anders Kiledal, Dongchang Zhao, Gregory Dick, Pavan Reddy
Journal: Blood
Blood (2023) 142 (Supplement 1): 2043.
https://doi.org/10.1182/blood-2023-191108
Published: 2023
Journal Articles

Rational Modification of Human Gut Microbiome and Metabolites By Dietary Resistant Starch in Allogeneic Hematopoietic Stem Cell Transplantation: A Feasibility Study

Mary Mansour Riwes, Jonathan Louis Golob, John M. Magenau, Costas Lyssiotis, Mengrou Shan, Gregory Dick, Thomas Braun, Thomas M Schmidt, Attaphol Pawarode, Sarah Anand, Monalisa Ghosh, John Maciejewski, Darren King, Sung W. Choi, Gregory Yanik, Marcus Johannes Geer, Ethan Hillman, Muneesh Tewari, Pavan Reddy
Journal: Blood
Blood (2023) 142 (Supplement 1): 2190.
https://doi.org/10.1182/blood-2023-181260
Published: 2023
Journal Articles

Absence of MHC Class I Expression on Target Cells Exacerbates Iron Dependent CD4+ T Cell Mediated Killing

Emma Lauder, Dongchang Zhao, Lu Li, Yaping Sun, Katherine Oravecz-Wilson, Laure Maneix, Ana Santibanez, Pavan Reddy
Journal: Blood
Blood (2023) 142 (Supplement 1): 3843.
https://doi.org/10.1182/blood-2023-191033
Published: 2023
Journal Articles

The Absence of NLRP6 in Donor T Cells Exacerbates Gvhd

Masahiro Suto, Eri Matsuki, Masahiro Miyata, Erika Sekiguchi, Hiroya Tamaki, Isao Tawara, Daniel Peltier, Grace Chen, Kenichi Ishizawa, Pavan Reddy, Tomomi Toubai
Journal: Blood
Blood (2021) 138 (Supplement 1): 2766.
https://doi.org/10.1182/blood-2021-152089
Published: 2021
Journal Articles

Mitochondrial Complex II in Intestinal Epithelial Cells Is a Critical Metabolic Checkpoint That Regulates Severity of Gastrointestinal Graft-Versus-Host Disease

Hideaki Fujiwara, Anna V Mathew, Ilya Kovalenko, Pal Anupama, Dan Peltier, Stephanie Kim, Austin Taylor, BA, Katherine Oravecz-Wilson, Yaping Sun, Costas Lyssiotis, Alnawaz Rehemtulla, Subramanian Pennarthur, Pavan Reddy
Journal: Blood
Blood (2019) 134 (Supplement_1): 584.
https://doi.org/10.1182/blood-2019-126775
Published: 2019
Journal Articles

ATG5 Dependent Autophagy in Graft-Versus-Host Disease Target Organs Mitigates Disease Severity Post Allogeneic Bone Marrow Transplant

Austin Taylor, BA, Kay Oravecz-Wilson, Hideaki Fujiwara, Stephanie Kim, Dan Peltier, Molly Radosevich, Yaping Sun, Pavan Reddy
Journal: Blood
Blood (2019) 134 (Supplement_1): 1914.
https://doi.org/10.1182/blood-2019-131879
Published: 2019
Journal Articles

NLRP6 in Donor T Cells Separately Regulates CD4 and CD8 Mediated Graft-Versus-Host Disease in Experimental Murine BMT

Masahiro Suto, Eri Matsuki, MD, Erika Sekiguchi, Hiroya Tamaki, MD PhD, Isao Tawara, MD PhD, Grace Chen, MD PhD, Kenichi Ishizawa, MD PhD, Pavan Reddy, Tomomi Toubai
Journal: Blood
Blood (2019) 134 (Supplement_1): 1926.
https://doi.org/10.1182/blood-2019-123875
Published: 2019
Journal Articles

The MAGIC Algorithm Probability (MAP): A Novel Laboratory Biomarker for the Response to Treatment of Acute Graft-Versus-Host Disease

Hrishikesh Srinagesh, BA, Umut Ozbek, PhD, Urvi Kapoor, MD, Francis Ayuketang Ayuk, MD, Mina D. Aziz, MD, Kaitlyn Ben-David, Hannah K. Choe, MD, Zachariah Defilipp, MD, Aaron Etra, MD, Stephan Grupp, MD PhD, Matthew Hartwell, MD, Elizabeth O. Hexner, MDMS, William J Hogan, MB, BCh, Carrie Kitko, MD, Steven Kowalyk, Jung-Yi Lin, MS, Hannah Major-Monfried, MD MSCR, Stephan Mielke, MD, Pietro Merli, MD, George Morales, Rainer Ordemann, MD, Michael A. Pulsipher, MD, Muna Qayed, MD MSc, Pavan Reddy, Ran Reshef, MD MSc, Wolf Roesler, MD, Karamjeet S. Sandhu, MD, Tal Schechter-Finkelstein, MD, Jay Shah, MD, Keith Sigel, MD PhD, Daniela Weber, MD, Matthias Wölfl, MD, Kitsada Wudhikarn, MD, Rachel Young, John E. Levine, MDMS, James L. M. Ferrara, MDDSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 367.
https://doi.org/10.1182/blood-2019-122011
Published: 2019
Journal Articles

Rational Modification of Intestinal Microbiome and Metabolites after Allogeneic Hematopoietic Stem Cell Transplantation with Resistant Starch: A Pilot Study

Mary Mansour Riwes, DO, Alexander Schmidt, Thomas Braun, John M. Magenau, MD, Attaphol Pawarode, Brian Parkin, Sarah Anand, MD, Monalisa Ghosh, John Maciejewski, Darren King, Muneesh Tewari, Sung W. Choi, Gregory A. Yanik, Kristi Maccready, Thomas Schmidt, Pavan Reddy
Journal: Blood
Blood (2019) 134 (Supplement_1): 3276.
https://doi.org/10.1182/blood-2019-131216
Published: 2019
Journal Articles

RNA-Seq of Human T Cells after BMT Identifies Linc00402 As a Novel Regulator of Human T Cell Alloimmunity

Dan Peltier, MD, Nicolas Robine, Guoqing Hou, PhD, Pavan Reddy, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4517.
https://doi.org/10.1182/blood-2018-99-113017
Published: 2018
Journal Articles

Donor T Cell Independent Mechanism Is Critical for Mediating Steroid Refractory Gvhd in Murine Models

Tomomi Toubai, MDPhD, Corrine Rossi, Isao Tawara, MD PhD, Chen Liu, MD PhD, Cynthia Zajac, Katherine Oravecz-Wilson, BS, MS, Dan Peltier, MD, Yaping Sun, MD PhD MS, Hideaki Fujiwara, MD, Mary Mansour Riwes, DO, Israel Henig, MD, Stephanie Kim, BS, Masahiro Suto, Kenichi Ishizawa, MD PhD, Pavan Reddy, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4529.
https://doi.org/10.1182/blood-2018-99-114634
Published: 2018
Journal Articles

Targeting Sec23b in COPII Vesicles Regulates T Cell Immunity

Stephanie Kim, BS, Rami Khoriaty, MD, Rajesh Valanparambil, PhD, Julia Wu, PhD, Austin Taylor, BS, Hideaki Fujiwara, MD, Dan Peltier, MD, Yaping Sun, MD PhD MS, Israel Henig, MD, Cynthia Zajac, Katherine Oravecz-Wilson, BS, MS, Stuart Brabbs, Rafi Ahmed, PhD, David Ginsburg, MD, Pavan Reddy, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 859.
https://doi.org/10.1182/blood-2018-99-111628
Published: 2018
Journal Articles

MAGIC biomarkers predict long-term outcomes for steroid-resistant acute GVHD

CME Clinical Trials & Observations
Hannah Major-Monfried, Anne S. Renteria, Attaphol Pawarode, Pavan Reddy, Francis Ayuk, Ernst Holler, Yvonne A. Efebera, William J. Hogan, Matthias Wölfl, Muna Qayed, Elizabeth O. Hexner, Kitsada Wudhikarn, Rainer Ordemann, Rachel Young, Jay Shah, Matthew J. Hartwell, Mohammed S. Chaudhry, Mina Aziz, Aaron Etra, Gregory A. Yanik, Nicolaus Kröger, Daniela Weber, Yi-Bin Chen, Ryotaro Nakamura, Wolf Rösler, Carrie L. Kitko, Andrew C. Harris, Michael Pulsipher, Ran Reshef, Steven Kowalyk, George Morales, Ivan Torres, Umut Özbek, James L. M. Ferrara, John E. Levine
Journal: Blood
Blood (2018) 131 (25): 2846–2855.
https://doi.org/10.1182/blood-2018-01-822957
Published: 2018
Includes: Supplemental data
Journal Articles

α 1 -Antitrypsin infusion for treatment of steroid-resistant acute graft-versus-host disease

Clinical Trials & Observations
John M. Magenau, Steven C. Goldstein, Dan Peltier, Robert J. Soiffer, Thomas Braun, Attaphol Pawarode, Mary M. Riwes, Maggi Kennel, Joseph H. Antin, Corey S. Cutler, Vincent T. Ho, Edwin P. Alyea, III, Brian L. Parkin, Gregory A. Yanik, Sung Won Choi, Eli C. Lewis, Charles A. Dinarello, John Koreth, Pavan Reddy
Journal: Blood
Blood (2018) 131 (12): 1372–1379.
https://doi.org/10.1182/blood-2017-11-815746
Published: 2018
Includes: Supplemental data
Journal Articles

Metabolic Reprogramming of Dendritic Cells Is Controlled By the Mir-142

Yaping Sun, MD PhD MS, Thomas Saunders, PhD, Katherine Oravecz-Wilson, BS, MS, Sydney Bridges, BS, Richard McEachin, PhD, Julia Wu, PhD, Stephanie Kim, Cynthia Zajac, Tomomi Toubai, MDPhD, Hideaki Fujiwara, Israel Henig, MD, Dan Peltier, MD, Pavan Reddy, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2265.
https://doi.org/10.1182/blood.V130.Suppl_1.2265.2265
Published: 2017
Journal Articles

Phase 2 Study of Pembrolizumab during Lymphodepleted State after Autologous Hematopoietic Cell Transplantation in Multiple Myeloma Patients

Attaphol Pawarode, MD, Anita D'Souza, MBBS, Marcelo C. Pasquini, MD, Bryon Johnson, PhD, Thomas Braun, PhD, Binod Dhakal, MBBS, Mehdi Hamadani, MD, John M. Magenau, MD, Nirav N Shah, MD, Mary Mansour Riwes, DO, Brian Parkin, MD, Pavan Reddy, MD, Parameswaran Hari, MD MRCP, MS
Journal: Blood
Blood (2017) 130 (Supplement 1): 339.
https://doi.org/10.1182/blood.V130.Suppl_1.339.339
Published: 2017
Journal Articles

Vorinostat plus tacrolimus/methotrexate to prevent GVHD after myeloablative conditioning, unrelated donor HCT

Clinical Trials & Observations
Sung Won Choi, Thomas Braun, Israel Henig, Erin Gatza, John Magenau, Brian Parkin, Attaphol Pawarode, Mary Riwes, Greg Yanik, Charles A. Dinarello, Pavan Reddy
Journal: Blood
Blood (2017) 130 (15): 1760–1767.
https://doi.org/10.1182/blood-2017-06-790469
Published: 2017
Journal Articles

Tissue tolerance: a distinct concept to control acute GVHD severity

Shin-Rong Wu, Pavan Reddy
Journal: Blood
Blood (2017) 129 (13): 1747–1752.
https://doi.org/10.1182/blood-2016-09-740431
Published: 2017