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Michael P Walsh
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Journal Articles

Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors

Juan M. Barajas, Milad Rasouli, Masayuki Umeda, Ryan Hiltenbrand, Sherif Abdelhamed, Rebecca Mohnani, Bright Arthur, Tamara Westover, Melvin E. Thomas, III, Minoo Ashtiani, Laura J. Janke, Beisi Xu, Ti-Cheng Chang, Wojciech Rosikiewicz, Emily Xiong, Chandra Rolle, Jonathan Low, Reethu Krishan, Guangchun Song, Michael P. Walsh, Jing Ma, Jeffrey E. Rubnitz, Ilaria Iacobucci, Taosheng Chen, Anja Krippner-Heidenreich, Christian M. Zwaan, Olaf Heidenreich, Jeffery M. Klco
Journal: Blood
Blood (2024) 143 (7): 619–630.
https://doi.org/10.1182/blood.2023021359
Published: 2024
Includes: Supplemental data
Journal Articles

Genetic and Functional Characterization of NUP98 -Rearranged Leukemia

Masayuki Umeda, Nicole Michmerhuizen, Ryan Hiltenbrand, Juan Barajas, Bright Arthur, Michael P Walsh, Guangchun Song, Jing Ma, Tamara Westover, Cristina Mecucci, Danika Di Giacomo, Franco Locatelli, Riccardo Masetti, Salvatore Bertuccio, Martina Pigazzi, Ilaria Iacobucci, Charles G. Mullighan, Jeffery M. Klco
Journal: Blood
Blood (2023) 142 (Supplement 1): 1562.
https://doi.org/10.1182/blood-2023-184622
Published: 2023
Journal Articles

UBTF Tandem Duplications in Pediatric MDS and AML: Implications for Clinical Screening and Diagnosis

Juan Barajas, Masayuki Umeda, Jing Ma, Mahsa Khanlari, Michael P Walsh, Tamara Westover, Lisett Contreras, Guangchun Song, Xiaotu Ma, Melvin Thomas, III, Jeffery M. Klco
Journal: Blood
Blood (2023) 142 (Supplement 1): 838.
https://doi.org/10.1182/blood-2023-172765
Published: 2023
Journal Articles

Comprehensive Genomic Landscape and Clonal Architecture in Pediatric Patients with Monosomy 7

Tamara Westover, Sherif Abdelhamed, Emily Xiong, Michael P Walsh, Jing Ma, Jasmine C. Wong, Astrid Behnert, Mignon L. Loh, Kevin M. Shannon, Jeffery M. Klco
Journal: Blood
Blood (2022) 140 (Supplement 1): 5837–5838.
https://doi.org/10.1182/blood-2022-166915
Published: 2022
Journal Articles

The Rise and Fall of Leukemia Clones in Longitudinal Samples from Diagnosis to Relapse in KMT2A- rearranged Infant and Childhood Leukemia

Louise Ahlgren, Mattias Pilheden, Helena Sturesson, Varsha Singh, Qirui Zhang, Anders Castor, Cornelis Jan Pronk, Gisela Barbany, Katja Pokrovskaja Tamm, Linda Fogelstrand, Michael P Walsh, Guangchun Song, Jinghui Zhang, Jing Ma, Anna Hagstroem-Andersson
Journal: Blood
Blood (2022) 140 (Supplement 1): 9189–9190.
https://doi.org/10.1182/blood-2022-165869
Published: 2022
Journal Articles

Tracking Clonal Evolution in Pediatric AML

Anna LW Huskey, Pandurang Kolekar, Tamara Westover, Jing Ma, Michael P Walsh, Masayuki Umeda, Guangchun Song, Yanling Liu, Quang Tran, Xiaotu Ma, Jeffery M. Klco
Journal: Blood
Blood (2022) 140 (Supplement 1): 8686–8687.
https://doi.org/10.1182/blood-2022-167256
Published: 2022
Journal Articles

UBTF -TD Expression Is Necessary and Sufficient for Myeloid Cell Expansion

Juan M. Barajas, Sherif Abdelhamed, Tamara Westover, Masayuki Umeda, Ryan Hiltenbrand, Bright Arthur, Reethu Krishnan, Michael P Walsh, Jing Ma, Jeffery M. Klco
Journal: Blood
Blood (2022) 140 (Supplement 1): 8733–8734.
https://doi.org/10.1182/blood-2022-159628
Published: 2022
Journal Articles

Integrated Genomic Analysis Identifies UBTF Tandem Duplications As a Subtype-Defining Lesion in Pediatric Acute Myeloid Leukemia

Masayuki Umeda, Jing Ma, Benjamin J. Huang, Kohei Hagiwara, Tamara Westover, Sherif Abdelhamed, Juan Martin Barajas, Melvin Edward Thomas, III, Michael P Walsh, Guangchun Song, Liqing Tian, Yanling Liu, Xiaolong Chen, Pandurang Kolekar, Quang Tran, Scott Foy, Jamie L. Maciaszek, Andrew B Kleist, Amanda R. Leonti, Bensheng Ju, John Easton, Huiyun Wu, Virginia Valentine, Marc Valentine, Yen-Chun Liu, Rhonda E. Ries, Jenny L. Smith, Evan Parganas, Ilaria Iacobucci, Ryan Hiltenbrand, Jonathan Miller, Jason Myers, Evadnie Rampersaud, Delaram Rahbarinia, Michael Rusch, Gang Wu, Hiroto Inaba, Yi-Cheng Wang, Todd A. Alonzo, James R. Downing, Charles G. Mullighan, Stanley B Pounds, M. Madan Babu, Jinghui Zhang, Jeffrey E. Rubnitz, Soheil Meshinchi, Xiaotu Ma, Jeffery M. Klco
Journal: Blood
Blood (2021) 138 (Supplement 2): LBA-4.
https://doi.org/10.1182/blood-2021-155134
Published: 2021
Journal Articles

The Molecular Landscape of KMT2A -Rearranged Leukemia from Infancy to Adulthood Reveals Age and Leukemia-Specific Mutational Patterns

Mattias Pilheden, Ton Falqués, Louise Ahlgren, Helena Sturesson, Michael P Walsh, Guangchun Song, Anders Castor, Cornelis Pronk, Hanne Vibeke Marquart, Birgitte Lausen, Gisela Barbany, Katja Pokrovskaja Tamm, Ullrika Norén-Nyström, Linda Fogelstrand, Olli Lohi, Axel Hyrenius Wittsten, Jinghui Zhang, James R. Downing, Jing Ma, Anna Hagstroem-Andersson
Journal: Blood
Blood (2021) 138 (Supplement 1): 3479.
https://doi.org/10.1182/blood-2021-152082
Published: 2021
Journal Articles

Comprehensive Genomic Profiling of Pediatric Therapy-Related Myeloid Neoplasms Identifies Mecom Dysregulation to be Associated with Poor Outcome

Jason R Schwartz, MD PhD, Jing Ma, PhD, Michael P Walsh, PhD, Xiaolong Chen, PhD, Tamara Lamprecht, BS, Jennifer Kamens, MD, Scott Newman, PhD, Jinghui Zhang, PhD, Tanja A. Gruber, MD PhD, Xiaotu Ma, Jeffery M. Klco, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1394.
https://doi.org/10.1182/blood-2019-128665
Published: 2019
Journal Articles

Integrative Analysis of Pediatric Acute Leukemia Identifies Immature Subtypes That Span a T Lineage and Myeloid Continuum with Distinct Prognoses

Tanja A. Gruber, MD PhD, Jing Ma, PhD, Sanne Noort, MD MSc, Yu Liu, PhD, Michael P Walsh, PhD, Stephanie Nance, PhD, Yanling Liu, PhD, Yuanyuan Wang, PhD, Guangchun Song, PhD, Tamara Lamprecht, BS, John Easton, PhD, Martina Pigazzi, PhD, Marie Jarosova, PhD, Kelaidi Charikleia, MD, Jeffrey Rubnitz, MD PhD, Dirk Reinhardt, MD, Marry M. van den Heuvel-Eibrink, Prof, MD PhD, Franco Locatelli, MD PhD, Henrik Hasle, Jeffery M. Klco, MD PhD, James R. Downing, MD, Stanley Pounds, PhD, Jinghui Zhang, PhD, Christian Michel Zwaan, MD PhD, Maarten Fornerod, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 918.
https://doi.org/10.1182/blood-2019-127411
Published: 2019
Journal Articles

The Mutational Profile of Pediatric Therapy-Related Myeloid Neoplasms

Jason R Schwartz, MD PhD, Michael P Walsh, PhD, Jing Ma, PhD, Tamara Lamprecht, B.S., Raul C Ribeiro, MD, Jeffery M. Klco, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2775.
https://doi.org/10.1182/blood-2018-99-118995
Published: 2018
Journal Articles

Assessing the Subclonal Genetic Landscape of KMT2A -Rearranged Infant Acute Lymphoblastic Leukemia By Single-Cell Genomics

Mattias Pilheden, MSc, Axel Hyrenius Wittsten, MSc, Veronica Gonzalez-Pena, PhD, Helena Sturesson, PhD, Michael P Walsh, PhD, Guangchun Song, PhD, Hanne Vibeke Marquart, MD PhD, Birgitte Lausen, MD PhD, Anders Castor, MD PhD, Jinghui Zhang, PhD, James R. Downing, MD, Jing Ma, PhD, Charles Gawad, MD PhD, Anna K. Andersson, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2709.
https://doi.org/10.1182/blood.V130.Suppl_1.2709.2709
Published: 2017
Journal Articles

Activating Mutations Are Potent Pro-Leukemic Mediators in Murine MLL-MLLT3 Leukemia That Cause Distinct Transcriptional Profiles

Axel Hyrenius-Wittsten, MSc, Helena Sturesson, PhD, Michael P. Walsh, PhD, Jenny Hansson, PhD, Julhash U. Kazi, PhD, Mattias Pilheden, MSc, Stephanie Nance, Pankaj Gupta, Guangchun Song, PhD, Jinghui Zhang, PhD, Jing Ma, PhD, Tanja A. Gruber, MD PhD, James R. Downing, MD PhD, Anna K. Andersson, PhD
Journal: Blood
Blood (2016) 128 (22): 3918.
https://doi.org/10.1182/blood.V128.22.3918.3918
Published: 2016
Journal Articles

The Genomic Landscape of Pediatric Myelodysplastic Syndromes

Jason R. Schwartz, MD PhD, Michael P. Walsh, PhD, Jing Ma, PhD, Tamara Lamprecht, B.S., Shuoguo Wang, PhD, Gang Wu, PhD, John Easton, PhD, Raul C. Ribeiro, MD, Jeffery M. Klco, MD PhD
Journal: Blood
Blood (2016) 128 (22): 956.
https://doi.org/10.1182/blood.V128.22.956.956
Published: 2016
Journal Articles

Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms

Benjamin Heath Durham, MD BS, Eli L. Diamond, MD, Julien Haroche, MD PhD, Zhan Yao, PhD, Jing Ma, PhD, Sameer A. Parikh, MD, John Choi, Eunhee Kim, PhD, Fleur Cohen-Aubart, Stanley Chun-Wei Lee, Yijun Gao, Jean-Baptiste Micol, MD, Patrick Campbell, MD PhD, Michael P. Walsh, Brooke Sylvester, Igor Dolgalev, Aminova Olga, Adriana Heguy, Paul Zappile, Joy Nakitandwe, BSc,MSc,PhD, James Dalton, BS, David W Ellison, MD, Juvianee Estrada-Veras, Mario Lacouture, William A. Gahl, MD PhD, Phil Stephens, PhD, Vincent A. Miller, MD, Jeffrey Ross, Siraj Ali, Sebastien Héritier, Jean Donadieu, MD PhD, David Solit, MD, David M. Hyman, Jose Baselga, MD PhD, Filip Janku, MDPhD, Barry S. Taylor, PhD, Christopher Y. Park, MD, PhD, Ahmet Dogan, MD PhD, Zahir Amoura, Jean-Francois Emile, Raajit K. Rampal, MD, PhD, Neal Rosen, MD PhD, Tanja A. Gruber, MD PhD, Omar Abdel-Wahab
Journal: Blood
Blood (2015) 126 (23): 481.
https://doi.org/10.1182/blood.V126.23.481.481
Published: 2015
Journal Articles

Unraveling the Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms through Whole Exome Sequencing

Benjamin Durham, MD, Jing Ma, PhD, Eunhee Kim, PhD, John K. Choi, MD, Patrick Campbell, MD PhD, Juvianee Estrada-Veras, MD, Michael P Walsh, PhD, Mario E Lacouture, MD, Young Rock Chung, MS, Joy Nakitandwe, PhD, Eli Diamond, David M. Hyman, MD, Raajit K. Rampal, MD PhD, Minal Patel, Christopher Y. Park, MD PhD, Tanja A. Gruber, MD PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2014) 124 (21): 1887.
https://doi.org/10.1182/blood.V124.21.1887.1887
Published: 2014
Journal Articles

Novel AMKL Chimeric Transcription Factors Are Potent Inducers of Leukemia with Unique Mechanisms of Leukemogenesis

Jinjun Dang, PhD, Stephanie Nance, PhD, Amanda Larson Gedman, PhD, Jinjun Cheng, MD PhD, Jing Ma, PhD, Michael P Walsh, PhD, Cary Koss, BS, Peter Vogel, DVM, PhD, James R Downing, MD, Tanja A Gruber, MD PhD
Journal: Blood
Blood (2014) 124 (21): 477.
https://doi.org/10.1182/blood.V124.21.477.477
Published: 2014