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Cornelis Jan Pronk
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Journal Articles

Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4 -r cases

Hanna Thorsson, Rasmus Henningsson, Noelia Puente-Moncada, Pablo Peña-Martínez, Ludvig Sjöström, Helena Ågerstam, Carl Sandén, Marianne Rissler, Anders Castor, Hanne Marquart, Signe Modvig, Kajsa Paulsson, Cornelis Jan Pronk, Kjeld Schmiegelow, Axel Hyrenius-Wittsten, Christina Orsmark-Pietras, Henrik Lilljebjörn, Thoas Fioretos
Journal: Blood
Blood (2024) 144 (13): 1399–1411.
https://doi.org/10.1182/blood.2023021705
Published: 2024
Includes: Supplemental data
Journal Articles

The Relapse Mechanisms and Genomic Landscape Differ in KMT2A -r Pediatric Leukemia in Relation to Relapse Time

Louise Ahlgren, Mattias Pilheden, Helena Sturesson, Varsha Singh, Qirui Zhang, Michael Walsh, Guangchun Song, Anders Castor, Cornelis Jan Pronk, Pauline Schneider, Ronald W. Stam, Gisela Barbany, Katja Pokrovskaja Tamm, Jonas Abrahamsson, Linda Fogelstrand, Olli Lohi, Jing Ma, Jinghui Zhang, Anna K. Hagstroem-Andersson
Journal: Blood
Blood (2023) 142 (Supplement 1): 2978.
https://doi.org/10.1182/blood-2023-185044
Published: 2023
Journal Articles

A Randomized Comparison of Liposomal Daunorubicin/Daunorubicin Combined with Low-Dose Cytarabine and Etoposide or High-Dose Cytarabine and Fludarabine in Induction Treatment of Pediatric AML Using MRD-Based Risk Stratification in the NOPHO-DBH AML 2012 Protocol

Barbara De Moerloose, Nira Arad-Cohen, Daniel Cheuk, Jose Maria Fernandez Navarro, Henrik Hasle, Kirsi Jahnukainen, Gertjan J.L. Kaspers, Zhanna Kovalova, Birgitte Lausen, Ulrika Norén-Nyström, Josefine Palle, Ramune Pasauliene, Cornelis Jan Pronk, Kadri Saks, Anne Maria Tierens, Bernward Zeller, Jonas Abrahamsson
Journal: Blood
Blood (2023) 142 (Supplement 1): 831.
https://doi.org/10.1182/blood-2023-187251
Published: 2023
Journal Articles

Management of Hyperleukocytosis in Pediatric Acute Myeloid Leukemia Using Immediate Chemotherapy without Leukapheresis, in Protocol NOPHO-DBH AML-2012

Bernward Zeller, Nira Arad-Cohen, Daniel Cheuk, Barbara De Moerloose, Jose Maria Fernandez Navarro, Henrik Hasle, Jahnukainen Kirsi, Kristian Juul-Dam, Gertjan J.L. Kaspers, Zhanna Kovalova, Birgitte Lausen, Monica C. Munthe-Kaas, Ulrika Norén-Nyström, Josefine Palle, Ramune Pasauliene, Cornelis Jan Pronk, Kadri Saks, Anne Maria Tierens, Jonas Abrahamsson
Journal: Blood
Blood (2023) 142 (Supplement 1): 2852.
https://doi.org/10.1182/blood-2023-184921
Published: 2023
Journal Articles

Chip-AML22 Master Protocol: An Open-Label Clinical Trial in Newly Diagnosed Pediatric De Novo Acute Myeloid Leukemia (AML) Patients Including a Linked Phase II Trial with Quizartinib in FLT3 -ITD/ NPM1 wt Patients - a Study By the NOPHO-DB-SHIP Consortium

Gertjan J.L. Kaspers, Noa E. Wijnen, Joost B. Koedijk, Sae Ishimaru, Renske Benedictus, Ellen C. Van Opstal, Harm Van Tinteren, C. Michel Zwaan, Noha Biserna, Pamela Downs, Yvonne Duong, Yasser Mostafa Kamel, Jonas Abrahamsson, Nira Arad-Cohen, Nicole Bodmer, Luis Castillo, Daniel Cheuk, Vitor Costa, Barbara De Moerloose, Jose Maria Fernandez Navarro, Linda Fogelstrand, Bianca F. Goemans, Henrik Hasle, Olafur G. Jonsson, Zhanna Kovalova, Monica C. Munthe-Kaas, Ulrika Norén-Nyström, Sauli Palmu, Ramune Pasauliene, Kadri Saks, Anne Maria Tierens, Dominik Turkiewicz, Cornelis Jan Pronk
Journal: Blood
Blood (2023) 142 (Supplement 1): 1532.
https://doi.org/10.1182/blood-2023-181792
Published: 2023
Journal Articles

Single Cell Multi-Omic Profiling of Acute Lymphoblastic Leukemia Identifies Altered Cellular Pathways and Highlights Heterogeneity in the Maturation Block of DUX4 -Rearranged ALL

Hanna Thorsson, Rasmus Henningsson, Noelia Puente-Moncada, Carl Sandén, Signe Modvig, Marianne Rissler, Kajsa Paulsson, Anders Castor, Cornelis Jan Pronk, Hanne Vibeke Marquart, Kjeld Schmiegelow, Christina Orsmark-Pietras, Henrik Lilljebjörn, Thoas Fioretos
Journal: Blood
Blood (2022) 140 (Supplement 1): 3467–3468.
https://doi.org/10.1182/blood-2022-163031
Published: 2022
Journal Articles

The Rise and Fall of Leukemia Clones in Longitudinal Samples from Diagnosis to Relapse in KMT2A- rearranged Infant and Childhood Leukemia

Louise Ahlgren, Mattias Pilheden, Helena Sturesson, Varsha Singh, Qirui Zhang, Anders Castor, Cornelis Jan Pronk, Gisela Barbany, Katja Pokrovskaja Tamm, Linda Fogelstrand, Michael P Walsh, Guangchun Song, Jinghui Zhang, Jing Ma, Anna Hagstroem-Andersson
Journal: Blood
Blood (2022) 140 (Supplement 1): 9189–9190.
https://doi.org/10.1182/blood-2022-165869
Published: 2022
Journal Articles

Treatment Outcomes of Childhood Picalm:MLLT10 + Acute Leukemias: An International Retrospective Study

Catherine Mark, Edward A. Kolb, Bianca F. Goemans, Soheil Meshinchi, Brenda Gibson, Anke K. Bergmann, Christine J. Harrison, Cornelis Jan Pronk, Hélène Lapillonne, Guy Leverger, Evangelia Antoniou, Andishe Attarbaschi, Michael Dworzak, Jan Stary, Daisuke Tomizawa, Monika Lejman, Kjeld Schmiegelow, Henrik Hasle, Brooklyn Joyce, Markus Schneider, Oussama Abla
Journal: Blood
Blood (2022) 140 (Supplement 1): 3403–3404.
https://doi.org/10.1182/blood-2022-156731
Published: 2022
Journal Articles

Central Nervous System Involvement Detected By Flow Cytometry Is a Risk Factor for Relapse in Childhood Acute Lymphoblastic Leukemia

Maria Thastrup, PhD, Hanne Vibeke Marquart, MD PhD, Mette Levinsen, PhD, Kathrine Grell, PhD, Jonas Abrahamsson, Birgitte Klug Albertsen, MD, Thomas Leth Frandsen, MD PhD, Arja Harila-Saari, MD Associate professor, Päivi Maria Lähteenmäki, MD PhD, Riitta Niinimäki, MD, Cornelis Jan Pronk, MD PhD, Aina Ulvmoen, PhD, Goda Vaitkeviciene, MD, Mervi Taskinen, MD PhD, Kjeld Schmiegelow, MD DMSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 657.
https://doi.org/10.1182/blood-2018-99-114173
Published: 2018
Journal Articles

Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS, and neurological symptoms

Bianca Tesi, Josef Davidsson, Matthias Voss, Elisa Rahikkala, Tim D. Holmes, Samuel C. C. Chiang, Jonna Komulainen-Ebrahim, Sorina Gorcenco, Alexandra Rundberg Nilsson, Tim Ripperger, Hannaleena Kokkonen, David Bryder, Thoas Fioretos, Jan-Inge Henter, Merja Möttönen, Riitta Niinimäki, Lars Nilsson, Cornelis Jan Pronk, Andreas Puschmann, Hong Qian, Johanna Uusimaa, Jukka Moilanen, Ulf Tedgård, Jörg Cammenga, Yenan T. Bryceson
Journal: Blood
Blood (2017) 129 (16): 2266–2279.
https://doi.org/10.1182/blood-2016-10-743302
Published: 2017
Includes: Supplemental data