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Journal Articles

Landscape of driver mutations and their clinical effects on Down syndrome–related myeloid neoplasms

Tomohiko Sato, Kenichi Yoshida, Tsutomu Toki, Rika Kanezaki, Kiminori Terui, Ryunosuke Saiki, Masami Ojima, Yotaro Ochi, Seiya Mizuno, Masaharu Yoshihara, Tamayo Uechi, Naoya Kenmochi, Shiro Tanaka, Jun Matsubayashi, Kenta Kisai, Ko Kudo, Kentaro Yuzawa, Yuka Takahashi, Tatsuhiko Tanaka, Yohei Yamamoto, Akie Kobayashi, Takuya Kamio, Shinya Sasaki, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Hideki Muramatsu, Asahito Hama, Daisuke Hasegawa, Atsushi Sato, Katsuyoshi Koh, Shuhei Karakawa, Masao Kobayashi, Junichi Hara, Yuichi Taneyama, Chihaya Imai, Daiichiro Hasegawa, Naoto Fujita, Masahiro Yoshitomi, Shotaro Iwamoto, Genki Yamato, Satoshi Saida, Nobutaka Kiyokawa, Takao Deguchi, Masafumi Ito, Hidemasa Matsuo, Souichi Adachi, Yasuhide Hayashi, Takashi Taga, Akiko M. Saito, Keizo Horibe, Kenichiro Watanabe, Daisuke Tomizawa, Satoru Miyano, Satoru Takahashi, Seishi Ogawa, Etsuro Ito

Blood (2024) 143 (25): 2627–2643.

https://doi.org/10.1182/blood.2023022247

Published: 2024

Includes: Supplemental data

Journal Articles

TCRαβ + /CD19 + - Depleted HLA-Haploidentical Hematopoietic Stem Cell Traansplantation in Pediatric Patient with Fanconi Anemia

Daria Pagliara, Luisa Strocchio, Francesca Compagno, Mattia Algeri, Akihiro Iguchi, Giovanna Giorgiani, Francesca Del Bufalo, Federica Galaverna, Pietro Merli, Cesare Perotti, Stefania Lazzaro, Giuseppina Li Pira, Valentina Bertaina, Daisuke Tomizawa, Marco Zecca, Franco Locatelli

Blood (2023) 142 (Supplement 1): 3528.

https://doi.org/10.1182/blood-2023-189870

Published: 2023

Journal Articles

Higher CD34+ Cell Doses Correlate with Reduced Incidence of Relapse and Better Event-Free Survival after KIR-Ligand Mismatch Cord Blood Transplantation for Childhood Acute Myeloid Leukemia

Hisashi Ishida, Yuta Kawahara, Daisuke Tomizawa, Yasuhiro Okamoto, Yuko Cho, Katsuyoshi Koh, Yuhki Koga, Asahito Hama, Maho Sato, Kiminori Terui, Naoyuki Miyagawa, Akihiro Watanabe, Junko Takita, Koji Kato, Kimikazu Matsumoto, Moeko Hino, Ken Tabuchi, Hirotoshi Sakaguchi

Blood (2023) 142 (Supplement 1): 2843.

https://doi.org/10.1182/blood-2023-174310

Published: 2023

Journal Articles

STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young

Shunsuke Kimura, Petri Pölönen, Lindsey Montefiori, Kenneth Caldwell, Ilaria Iacobucci, Chelsey Chen, Anthony Brown, Katie Han, Yen-Chun Liu, Yunchao Chang, Zhongshan Cheng, Zhou Yinmei, Chun Shik Park, Sharnise Mitchell, Noemi Reyes, Allen Yeoh, Andishe Attarbaschi, Andrew Moore, Atsushi Manabe, Barbara Buldini, Kean Hui Chiew, Chi Kong Li, Ching-Hon Pui, Chunxu Qu, Daisuke Tomizawa, Elisabeth Paietta, Franco Locatelli, Gabriele Escherich, Gao Qingsong, Hannah Elisa Muhle, Hanne Vibeke Marquart, Hester A. de Groot-Kruseman, Jacob M. Rowe, Jan Stary, Jan Trka, John Kim Choi, Jules P.P. Meijerink, Junko Takita, Katarzyna Pawinska-Wasikowska, Kjeld Schmiegelow, Mariko Eguchi, Martin Schrappe, Martin Zimmermann, Masatoshi Takagi, Melissa Maybury, Michael Svaton, Michaela Reiterova, Michal Kicinski, Motohiro Kato, Orietta Spinelli, Pauline Mazilier, Paul G. Thomas, Riccardo Masetti, Rishi Sury Kotecha, Rob Pieters, Sarah Elitzur, Selina M Luger, Shuhong Shen, Sima Jeha, Steven M. Kornblau, Szymon Skoczen, Takako Miyamura, Tiffaney Vincent, Toshihiko Imamura, Valentino Conter, Yanjing Tang, Zhaohui Gu, Kathryn G. Roberts, David T. Teachey, Kristine R Crews, Cheng Cheng, Jun J. Yang, Hiroto Inaba, Charles G. Mullighan

Blood (2023) 142 (Supplement 1): 845.

https://doi.org/10.1182/blood-2023-178688

Published: 2023

Journal Articles

Metabolic Reprogramming By PRDM16 Drives Cytarabine Resistance in Acute Myeloid Leukemia

Blood (2023) 142 (Supplement 1): 2740.

https://doi.org/10.1182/blood-2023-181740

Published: 2023

Journal Articles

Integrated Analysis Focusing on Genome-Wide DNA Methylation in Pediatric Acute Promyelocytic Leukemia: The Jccg Study, JPLSG AML-P05

Etsuko Ishikita, Tomoko Kawai, Genki Yamato, Norio Shiba, Kentaro Ohki, Yusuke Hara, Taeko Kaburagi, Takumi Takizawa, Hirohide Kawasaki, Hiroo Ueno, Daisuke Tomizawa, Takashi Taga, Souichi Adachi, Yuki Yuza, Hiroyuki Takahashi, Seishi Ogawa, Yasuhide Hayashi

Blood (2023) 142 (Supplement 1): 2966.

https://doi.org/10.1182/blood-2023-179285

Published: 2023

Journal Articles

Integrated Analysis of KIT Exon 17 Mutations and Flow-MRD Refines Risk Stratification in Pediatric Acute Myeloid Leukemia with RUNX1 :: RUNX1T1

Shin-Ichi Tsujimoto, Shota Kato, Shotaro Iwamoto, Hidefumi Hiramatsu, Yusuke Okuno, Tatsuya Kamitori, Kentaro Ohki, Takao Deguchi, Nobutaka Kiyokawa, Motohiro Kato, Junko Takita, Souichi Adachi, Daisuke Tomizawa, Norio Shiba

Blood (2023) 142 (Supplement 1): 1599.

https://doi.org/10.1182/blood-2023-181358

Published: 2023

Journal Articles

Evaluation of High-Dose Cytarabine Induction Therapy and Flow Cytometric Measurable Residual Disease Monitoring for Children with De Novo Acute Myeloid Leukemia: A Report from the JPLSG-AML-12 Trial

Blood (2022) 140 (Supplement 1): 1450–1452.

https://doi.org/10.1182/blood-2022-158664

Published: 2022

Journal Articles

Prognosis of Pediatric Acute Myeloid Leukemia with KMT2A-MLLT3 According to DNA Methylation Patterns: Jccg JPLSG AML-05 Study

Blood (2022) 140 (Supplement 1): 9134–9135.

https://doi.org/10.1182/blood-2022-163226

Published: 2022

Journal Articles

Treatment Outcomes of Childhood Picalm:MLLT10 + Acute Leukemias: An International Retrospective Study

Blood (2022) 140 (Supplement 1): 3403–3404.

https://doi.org/10.1182/blood-2022-156731

Published: 2022

Journal Articles

Safety and Efficacy of Arsenic Trioxide in the Treatment of Newly Diagnosed Pediatric Acute Promyelocytic Leukemia: Results from the JPLSG AML-P13 Study

Hiroyuki Takahashi, Shiro Tanaka, Yuki Yuza, Yuka Iijima-Yamashita, Daisuke Hasegawa, Hiroshi Moritake, Kiminori Terui, Shotaro Iwamoto, Akira Shimada, Jun Matsubayashi, Takao Deguchi, Yoshiko Hashii, Nobutaka Kiyokawa, Hayato Miyachi, Akiko Moriya Saito, Takashi Taga, Souichi Adachi, Daisuke Tomizawa

Blood (2022) 140 (Supplement 1): 6160–6161.

https://doi.org/10.1182/blood-2022-162177

Published: 2022

Journal Articles

Impact of Allogeneic Hematopoietic Stem Cell Transplantation in First Complete Remission and Additional Cytogenetic Aberrations at Diagnosis on Prognosis in 1256 Pediatric Patients with KMT2A-Rearranged Acute Myeloid Leukemia: A Retrospective Study By the I-BFM-SG

Blood (2021) 138 (Supplement 1): 2360.

https://doi.org/10.1182/blood-2021-148041

Published: 2021

Journal Articles

Intensification of Early-Phase Therapy to Diminish the Prognostic Effect of Myeloid Antigen Expression in Infants with KMT2A -Rearranged Acute Lymphoblastic Leukemia: A Report from the JPLSG MLL-10 Trial

Yuki Arakawa, Takashi Ishihara, Takako Miyamura, Takao Deguchi, Masashi Sanada, Toshinori Hori, Tomomi Yamada, Yuki Aoki, Sae Ishimaru, Takayuki Takachi, Mio Yano, Shinya Sasaki, Akiko M Saito, Atsushi Manabe, Keizo Horibe, Toshihiko Imamura, Daisuke Tomizawa

Blood (2021) 138 (Supplement 1): 2384.

https://doi.org/10.1182/blood-2021-145955

Published: 2021

Journal Articles

Clonal Evolution Pattern and Prognostic Significance of Clonal Architecture in KMT2A -Rearranged Acute Myeloid Leukemia

Blood (2021) 138 (Supplement 1): 2358.

https://doi.org/10.1182/blood-2021-146699

Published: 2021

Journal Articles

Etoposide, Cytarabine and Mitoxantrone- or Fludarabine, Cytarabine and Granulocyte Colony-Stimulating Factor-Based Intensive Reinduction Chemotherapy Is Recommended for Children with Relapsed Acute Myeloid Leukemia: The Results from the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) AML-05R Study

Hiroshi Moritake, MD PhD, Shiro Tanaka, PhD, Takako Miyamura, MD PhD, Hideki Nakayama, MD, Norio Shiba, MD PhD, Akira Shimada, MDPhD, Kiminori Terui, MD PhD, Yuki Yuza, MD PhD, Katsuyoshi Koh, MD, Hiroaki Goto, MD, PhD, Harumi Kakuda, MD PhD, Akiko M Saito, MD PhD, Daisuke Hasegawa, MD PhD, Shotaro Iwamoto, MD, Takashi Taga, MD PhD, Souichi Adachi, MD PhD, Daisuke Tomizawa, MD PhD

Blood (2020) 136 (Supplement 1): 6.

https://doi.org/10.1182/blood-2020-133272

Published: 2020

Journal Articles

Outcome of (Novel) Subgroups in 1257 Pediatric Patients with KMT2A-Rearranged Acute Myeloid Leukemia (AML) and the Significance of Minimal Residual Disease (MRD) Status: A Retrospective Study By the I-BFM-SG

Blood (2020) 136 (Supplement 1): 26–27.

https://doi.org/10.1182/blood-2020-136064

Published: 2020

Journal Articles

KRAS mutations Frequently Coexist with High-Risk MLL Fusions and Are Independent Adverse Prognostic Factors in MLL -Rearranged Acute Myeloid Leukemia

Blood (2020) 136 (Supplement 1): 28–29.

https://doi.org/10.1182/blood-2020-134648

Published: 2020

Journal Articles

A risk-stratified therapy for infants with acute lymphoblastic leukemia: a report from the JPLSG MLL-10 trial

Blood (2020) 136 (16): 1813–1823.

https://doi.org/10.1182/blood.2019004741

Published: 2020

Includes: Supplemental data

Journal Articles

Clinical Features of Children with Polycythemia Vera, Essential Thrombocythemia, and Primary Myelofibrosis in Japan: Retrospective Nationwide Survey

Hisashi Ishida, MD PhD, Takeo Sarashina, MD PhD, Risa Matsumura, Katsutsugu Umeda, MD, PhD, Tetsuo Mitsui, MD PhD, Naoto Fujita, MD PhD, Daisuke Tomizawa, MD PhD, Kevin Y Urayama, PhD MPH, Yasushi Ishida, MD PhD, Takashi Taga, MD PhD, Masatoshi Takagi, MD PhD, Souichi Adachi, MD PhD, Atsushi Manabe, MD PhD, Toshihiko Imamura, MD PhD, Katsuyoshi Koh, MD, Akira Shimada, MD PhD

Blood (2019) 134 (Supplement_1): 2958.

https://doi.org/10.1182/blood-2019-123429

Published: 2019

Journal Articles

NUDT15 Variants Confer High Incidence of Secondary Malignancies of ALL in Children

Blood (2019) 134 (Supplement_1): 2751.

https://doi.org/10.1182/blood-2019-125713

Published: 2019

NARROW

Landscape of driver mutations and their clinical effects on Down syndrome–related myeloid neoplasms

TCRαβ + /CD19 + - Depleted HLA-Haploidentical Hematopoietic Stem Cell Traansplantation in Pediatric Patient with Fanconi Anemia

Higher CD34+ Cell Doses Correlate with Reduced Incidence of Relapse and Better Event-Free Survival after KIR-Ligand Mismatch Cord Blood Transplantation for Childhood Acute Myeloid Leukemia

STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young

Metabolic Reprogramming By PRDM16 Drives Cytarabine Resistance in Acute Myeloid Leukemia

Integrated Analysis Focusing on Genome-Wide DNA Methylation in Pediatric Acute Promyelocytic Leukemia: The Jccg Study, JPLSG AML-P05

Integrated Analysis of KIT Exon 17 Mutations and Flow-MRD Refines Risk Stratification in Pediatric Acute Myeloid Leukemia with RUNX1 :: RUNX1T1

Evaluation of High-Dose Cytarabine Induction Therapy and Flow Cytometric Measurable Residual Disease Monitoring for Children with De Novo Acute Myeloid Leukemia: A Report from the JPLSG-AML-12 Trial

Prognosis of Pediatric Acute Myeloid Leukemia with KMT2A-MLLT3 According to DNA Methylation Patterns: Jccg JPLSG AML-05 Study

Treatment Outcomes of Childhood Picalm:MLLT10 + Acute Leukemias: An International Retrospective Study

Safety and Efficacy of Arsenic Trioxide in the Treatment of Newly Diagnosed Pediatric Acute Promyelocytic Leukemia: Results from the JPLSG AML-P13 Study

Impact of Allogeneic Hematopoietic Stem Cell Transplantation in First Complete Remission and Additional Cytogenetic Aberrations at Diagnosis on Prognosis in 1256 Pediatric Patients with KMT2A-Rearranged Acute Myeloid Leukemia: A Retrospective Study By the I-BFM-SG

Intensification of Early-Phase Therapy to Diminish the Prognostic Effect of Myeloid Antigen Expression in Infants with KMT2A -Rearranged Acute Lymphoblastic Leukemia: A Report from the JPLSG MLL-10 Trial

Clonal Evolution Pattern and Prognostic Significance of Clonal Architecture in KMT2A -Rearranged Acute Myeloid Leukemia

Outcome of (Novel) Subgroups in 1257 Pediatric Patients with KMT2A-Rearranged Acute Myeloid Leukemia (AML) and the Significance of Minimal Residual Disease (MRD) Status: A Retrospective Study By the I-BFM-SG

KRAS mutations Frequently Coexist with High-Risk MLL Fusions and Are Independent Adverse Prognostic Factors in MLL -Rearranged Acute Myeloid Leukemia

A risk-stratified therapy for infants with acute lymphoblastic leukemia: a report from the JPLSG MLL-10 trial

Clinical Features of Children with Polycythemia Vera, Essential Thrombocythemia, and Primary Myelofibrosis in Japan: Retrospective Nationwide Survey

NUDT15 Variants Confer High Incidence of Secondary Malignancies of ALL in Children

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