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Motohiro Kato
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Journal Articles

STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young

Shunsuke Kimura, Petri Pölönen, Lindsey Montefiori, Kenneth Caldwell, Ilaria Iacobucci, Chelsey Chen, Anthony Brown, Katie Han, Yen-Chun Liu, Yunchao Chang, Zhongshan Cheng, Zhou Yinmei, Chun Shik Park, Sharnise Mitchell, Noemi Reyes, Allen Yeoh, Andishe Attarbaschi, Andrew Moore, Atsushi Manabe, Barbara Buldini, Kean Hui Chiew, Chi Kong Li, Ching-Hon Pui, Chunxu Qu, Daisuke Tomizawa, Elisabeth Paietta, Franco Locatelli, Gabriele Escherich, Gao Qingsong, Hannah Elisa Muhle, Hanne Vibeke Marquart, Hester A. de Groot-Kruseman, Jacob M. Rowe, Jan Stary, Jan Trka, John Kim Choi, Jules P.P. Meijerink, Junko Takita, Katarzyna Pawinska-Wasikowska, Kjeld Schmiegelow, Mariko Eguchi, Martin Schrappe, Martin Zimmermann, Masatoshi Takagi, Melissa Maybury, Michael Svaton, Michaela Reiterova, Michal Kicinski, Motohiro Kato, Orietta Spinelli, Pauline Mazilier, Paul G. Thomas, Riccardo Masetti, Rishi Sury Kotecha, Rob Pieters, Sarah Elitzur, Selina M Luger, Shuhong Shen, Sima Jeha, Steven M. Kornblau, Szymon Skoczen, Takako Miyamura, Tiffaney Vincent, Toshihiko Imamura, Valentino Conter, Yanjing Tang, Zhaohui Gu, Kathryn G. Roberts, David T. Teachey, Kristine R Crews, Cheng Cheng, Jun J. Yang, Hiroto Inaba, Charles G. Mullighan
Journal: Blood
Blood (2023) 142 (Supplement 1): 845.
https://doi.org/10.1182/blood-2023-178688
Published: 2023
Journal Articles

Outcomes of Hematopoietic Cell Transplantation for Patients with Refractory Cytopenia with Multilineage Dysplasia: A Comparison Children with Adolescents and Young Adults

Asahito Hama, Nao Yoshida, Daisuke Hasegawa, Motohiro Kato, Kenichiro Watanabe, Daiichiro Hasegawa, Tetsuya Nishida, Noriko Doki, Maho Sato, Yasushi Onishi, Takuro Nishikawa, Hiroshi Tujimoto, Katsuyoshi Koh, Tetsuya Mori, Koji Kato, Yoshiko Hashii, Atsushi Sato, Ken Tabuchi, Jun Aoki, Shohei Yamamoto
Journal: Blood
Blood (2023) 142 (Supplement 1): 2202.
https://doi.org/10.1182/blood-2023-189000
Published: 2023
Journal Articles

A Nationwide Clinical Trial ALL-B12: An Optimized Therapy for Pediatric B-Precursor Acute Lymphoblastic Leukemia with Excellent Overall Survival and Minimal Non-Relapse Mortality: A Report from the Japan Children's Cancer Group

Motohiro Kato, Yasuhiro Okamoto, Toshihiko Imamura, Akiko Kada, Akiko M Saito, Yuka Iijima-Yamashita, Takao Deguchi, Kentaro Oki, Takashi Fukushima, Ken-ichi Anami, Masashi Sanada, Tomohiko Taki, Yoshiko Hashii, Nobutaka Kiyokawa, Yoshiyuki Kosaka, NAO Yoshida, Yuki Yuza, Masakatsu Yanagimachi, Kenichiro Watanabe, Atsushi Sato, Chihaya Imai, Takashi Taga, Souichi Adachi, Keizo Horibe, Atsushi Manabe, Katsuyoshi Koh
Journal: Blood
Blood (2023) 142 (Supplement 1): 519.
https://doi.org/10.1182/blood-2023-182464
Published: 2023
Journal Articles

Integrated Analysis of KIT Exon 17 Mutations and Flow-MRD Refines Risk Stratification in Pediatric Acute Myeloid Leukemia with RUNX1 :: RUNX1T1

Shin-Ichi Tsujimoto, Shota Kato, Shotaro Iwamoto, Hidefumi Hiramatsu, Yusuke Okuno, Tatsuya Kamitori, Kentaro Ohki, Takao Deguchi, Nobutaka Kiyokawa, Motohiro Kato, Junko Takita, Souichi Adachi, Daisuke Tomizawa, Norio Shiba
Journal: Blood
Blood (2023) 142 (Supplement 1): 1599.
https://doi.org/10.1182/blood-2023-181358
Published: 2023
Journal Articles

Impact of Nelarabine, Intensive L-Asparaginase, and Protracted Intrathecal Therapy on Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia: Results from the Japanese Pediatric Leukemia/Lymphoma Study Group and the Japan Adult Leukemia Study Group

Atsushi Sato, Yoshihiro Hatta, Chihaya Imai, Koichi Oshima, Yasuhiro Okamoto, Takao Deguchi, Yoshiko Hashii, Takashi Fukushima, Toshinori Hori, Nobutaka Kiyokawa, Motohiro Kato, Shoji Saito, Kenichi Anami, Tatsuhiro Sakamoto, Akiko Kada, Akiko M Saito, Atsushi Manabe, Hitoshi Kiyoi, Itaru Matsumura, Keizo Horibe, Katsuyoshi Koh, Yasushi Miyazaki, Arata Watanabe
Journal: Blood
Blood (2021) 138 (Supplement 1): 3393.
https://doi.org/10.1182/blood-2021-149110
Published: 2021
Journal Articles

Outcomes of Haploidentical Salvage Transplantation Using Post-Transplant Cyclophosphamide for Graft Failure Following Allogeneic Hematopoietic Stem Cell Transplantation

Kaito Harada, Shigeo Fuji, Yuho Najima, Motohiro Kato, Akihito Shinohara, Masako Toyosaki, Hirohisa Nakamae, Daisuke Hasegawa, Hiroatsu Iida, Makoto Onizuka, Yoshiko Hashii, Tatsuo Ichinohe, Yoshiko Atsuta, Hideki Nakasone
Journal: Blood
Blood (2021) 138 (Supplement 1): 2871.
https://doi.org/10.1182/blood-2021-149549
Published: 2021
Journal Articles

Chemotherapy with the Use of TKIs Based on MRD Has the Potential to Avoid Hematopoietic Stem Cell Transplantation in Treatment for Children with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ALL). Results of the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) Study ALL-Ph13

Atsushi Sato, Hirohide Kawasaki, Takao Deguchi, Yoshiko Hashii, Yuka Iijima-Yamashita, Sachiko Yonezawa, Chiyo K Imamura, Haruko Shima, Hirotoshi Sakaguchi, Yuichi Kodama, Keisuke Kato, Motohiro Kato, Hidefumi Hiramatsu, Nobutaka Kiyokawa, Akiko Kada, Akiko M Saito, Keizo Horibe, Atsushi Manabe, Hiroyuki Shimada
Journal: Blood
Blood (2021) 138 (Supplement 1): 3394.
https://doi.org/10.1182/blood-2021-148264
Published: 2021
Journal Articles

A Retrospective Study on Inotuzumab Ozogamicin in Infants and Young Children with Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL)

Erica Brivio, MD, Raoull Hoogendijk, MSc, Christophe Chantrain, MD PhD, Fanny Rialland, MD, Audrey Contet, Sarah Elitzur, MD, Luciano Dalla-Pozza, MBBS FRACP, Krisztian Kallay, MD, Chi Kong Li, MBBS,MD, Motohiro Kato, MD PhD, Inna V Markova, Dr., Kjeld Schmiegelow, Professor MD DMSc., Nicole Bodmer, Rob Pieters, MDPhDMSc, Christian Michel Zwaan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3890.
https://doi.org/10.1182/blood-2019-126472
Published: 2019
Journal Articles

NUDT15 Variants Confer High Incidence of Secondary Malignancies of ALL in Children

Masanori Yoshida, MD, Kazuhiko Nakabayashi, PhD, Aiko Sato-Otsubo, PhD, Shinichi Tsujimoto, MD PhD, Kaoru Yoshida, MD, Ryota Shirai, MD, Tomoo Osumi, MD, Yuki Yuza, MD PhD, Masatoshi Takagi, MD PhD, Hiroyuki Takahashi, MD PhD, Katsuyoshi Koh, MD, Akitoshi Kinoshita, MD PhD, Moeko Hino, MD, Toshihiko Imamura, MD PhD, Yozo Nakazawa, MD PhD, Okuya Mayuko, MD PhD, Harumi Kakuda, MD PhD, Masashi Sanada, MD, Kimikazu Matsumoto, MD, PhD, Daisuke Tomizawa, MD PhD, Nobutaka Kiyokawa, MD PhD, Akira Ohara, MD PhD, Atsushi Manabe, MD PhD, Kenichiro Hata, MD PhD, Jun J. Yang, PhD, Motohiro Kato, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2751.
https://doi.org/10.1182/blood-2019-125713
Published: 2019
Journal Articles

Tolerable Dose of 6-Mercaptopurine and Prognostic Impact of NUDT15-Deficient Genotype in Childhood Acute Lymphoblastic Leukemia

Yoichi Tanaka, PhD, Motohiro Kato, MD PhD, Takaya Moriyama, MD PhD, Yuki Arakawa, MD, Daisuke Hasegawa, MD PhD, Junya Fujimura, MD PhD, Dai Keino, MD PhD, Atsushi Sato, MD, Takahiro Ueda, MD PhD, Yuichi Taneyama, MD, Masatoshi Takagi, MD PhD, Masaki Yamamoto, MD, Masaki Matsuoka, MD, Moeko Hino, MD, Hiroki Hori, MD PhD, Katsuyoshi Koh, MD, Allen Eng Juh Yeoh, MD, Jun J. Yang, PhD, Atsushi Manabe, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4032.
https://doi.org/10.1182/blood-2018-99-114290
Published: 2018
Journal Articles

Distribution and Clinical Features of NOTCH1 Signaling Activating Alterations in Pediatric T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Shunsuke Kimura, MD, Masafumi Seki, MD, PhD, Kenichi Yoshida, MD PhD, Hiroo Ueno, MD, Yasuhito Nannya, MD PhD, Kentaro Ohki, MD PhD, Motohiro Kato, MD PhD, Katsuyoshi Koh, MD, Ryoji Kobayashi, MD, Takao Deguchi, MD PhD, Yoshiko Hashii, MD PhD, Toshihiko Imamura, MD PhD, Atsushi Sato, MD, Nobutaka Kiyokawa, MD PhD, Atsushi Manabe, MD PhD, Keizo Horibe, MD PhD, Akira Ohara, MD, Masashi Sanada, MD PhD, Mitsuteru Hiwatari, MD PhD, Masao Kobayashi, MD PhD, Akira Oka, MD PhD, Satoru Miyano, PhD, Seishi Ogawa, MD PhD, Junko Takita, MD, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4089.
https://doi.org/10.1182/blood-2018-99-111092
Published: 2018
Journal Articles

Hematopoietic Stem Cell Transplantation in Children with Refractory Acute Lymphoblastic Leukemia

Yasuhiro Okamoto, MD, Yozo Nakazawa, MD, PhD, Masami Inoue, MD, Kenichiro Watanabe, MD PhD, Hiroaki Goto, MD, Nao Yoshida, MD PhD, Maiko Noguchi, MD, Atsushi Kikuta, MD, Koji Kato, MD PhD, Yoshiko Hashii, MD PhD, Yoshiko Atsuta, MD PhD, Motohiro Kato, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2173.
https://doi.org/10.1182/blood-2018-99-111301
Published: 2018
Journal Articles

Preclinical evaluation of NUDT15 -guided thiopurine therapy and its effects on toxicity and antileukemic efficacy

Rina Nishii, Takaya Moriyama, Laura J. Janke, Wenjian Yang, Chase C. Suiter, Ting-Nien Lin, Lie Li, Kentaro Kihira, Hidemi Toyoda, Ute Hofmann, Matthias Schwab, Masatoshi Takagi, Tomohiro Morio, Atsushi Manabe, Shirley Kham, Nan Jiang, Karen R. Rabin, Motohiro Kato, Katsuyoshi Koh, Allen Eng-Juh Yeoh, Hiroki Hori, Jun J. Yang
Journal: Blood
Blood (2018) 131 (22): 2466–2474.
https://doi.org/10.1182/blood-2017-11-815506
Published: 2018
Includes: Supplemental data
Journal Articles

Clinical Significance of Natural Killer Cell-Mediated Alloreactivity in Unrelated Cord Blood Transplantation for Children with Acute Leukemia: A Japanese National Registry Study

Hirotoshi Sakaguchi, MD PhD, Nobuyoshi Arima, MD PhD, Atsushi Narita, MD PhD, Sae Ishimaru, MD, Daisuke Tomizawa, MD PhD, Daiichiro Hasegawa, MD PhD, Motohiro Kato, MD, Hiroyuki Ishida, MD PhD, Junya Kanda, MD, Masami Inoue, MD PhD, Nao Yoshida, MD PhD, Katsuyoshi Koh, MD, Jiro Inagaki, MD PhD, Atsushi Ogawa, MD PhD, Tsukasa Hori, MD PhD, Yoshiko Hashii, MD, PhD, Koji Kato, MD, PhD, Yoshiko Atsuta, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3315.
https://doi.org/10.1182/blood.V130.Suppl_1.3315.3315
Published: 2017
Journal Articles

Evaluation of Nudt15 -Guided Thiopurine Dose Individualization In Vivo Using CRISPR/Cas9-Edited Mouse Model

Takaya Moriyama, MDPhD, Rina Nishii, Laura Janke, DVM, PhD, Lie Li, Chen Ru, Scott A Brown, PhD, Ting-Nien Lin, Chase Suiter, Kentaro Kihira, MD, Hidemi Toyoda, MD PhD, Motohiro Kato, MD PhD, Atushi Manabe, MD PhD, Katsuyoshi Koh, MD, Masatoshi Takagi, MD PhD, Hiroki Hori, MD PhD, Jun J. Yang, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3879.
https://doi.org/10.1182/blood.V130.Suppl_1.3879.3879
Published: 2017
Journal Articles

Nationwide Survey of Pediatric Hypodiploid Acute Lymphoblastic Leukemia in Japan

Sae Ishimaru, MD, Yasuhiro Okamoto, MD, Chihaya Imai, MD PhD, Hirotoshi Sakaguchi, MD PhD, Tomohiko Taki, MD PhD, Daisuke Hasegawa, MD PhD, Yuko Cho, MD, Harumi Kakuda, MD PhD, Hideki Sano, MD, Atushi Manabe, MD PhD, Toshihiko Imamura, MD, PhD, Motohiro Kato, MD, Yuki Arakawa, MD, Hidemi Shimonodan, MD, Atsushi Sato, MD, So-ichi Suenobu, MD PhD, Takeshi Inukai, MD, Arata Watanabe, MD, Yoshifumi Kawano, MD PhD, Atsushi Kikuta, MD, Keizo Horibe, Akira Ohara, MD, Katsuyoshi Koh, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5121.
https://doi.org/10.1182/blood.V130.Suppl_1.5121.5121
Published: 2017
Journal Articles

The Epigenetic and Genetic Landscapes of Pediatric T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Shunsuke Kimura, Masafumi Seki, MD,PhD, Tomoko Kawai, PhD, Kenichi Yoshida, MD PhD, Tomoya Isobe, Hiroo Ueno, MD, Yusuke Shiozawa, MD , PhD, Hiromichi Suzuki, MD , PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, B.A., Hiroko Tanaka, B.A., Kentaro Ohki, MD PhD, Motohiro Kato, MD, Katsuyoshi Koh, MD, Ryoji Hanada, MD, Ryoji Kobayashi, MD, Takao Deguchi, MD PhD, Yoshiko Hashii, MD, PhD, Toshihiko Imamura, MD, PhD, Atsushi Sato, MD, Nobutaka Kiyokawa, MD PhD, Atushi Manabe, MD PhD, Keizo Horibe, Akira Ohara, MD, Masashi Sanada, MD PhD, Masao Kobayashi, MD PhD, Akira Oka, MD PhD, Yasuhide Hayashi, MD PhD, Satoru Miyano, PhD, Kenichiro Hata, MD PhD, Seishi Ogawa, MD PhD, Junko Takita, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1444.
https://doi.org/10.1182/blood.V130.Suppl_1.1444.1444
Published: 2017
Journal Articles

Hip Osteonecrosis in Pediatric Leukemia/Lymphoma Patients Treated with Glucocorticoids: Retrospective Analysis in a Single Institute

Yuki Arakawa, MD, Makiko Mori, MD, Masahiro Sugawa, MD, Jun Noguchi, MD, Ryota Kawakami, MD, Toshikazu Itabashi, MD, Masato Yanagi, MD, Kiyotaka Isobe, MD, Motohiro Kato, MD, Eiji Oguma, MD, Katsuaki Taira, MD, Katsuyoshi Koh, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5014.
https://doi.org/10.1182/blood.V130.Suppl_1.5014.5014
Published: 2017
Journal Articles

Clonal Evolution Mechanisms and Collateral Sensitivity to Impdh Inhibitor Therapy in Relapsed Lymphoblastic Leukemia

Chelsea Dieck, Gannie Tzoneva, PhD, Koichi Oshima, MD PhD, Alberto Ambesi-Impiombato, Marta Sanchez-Martin, PhD, Maria Luisa Sulis, MD, Motohiro Kato, MD PhD, Katsuyoshi Koh, MD, Maddalena Paganin, PhD, Giuseppe Basso, MD, Julie M. Gastier-Foster, PhD, Mignon L. Loh, MD, Renate Kirschner-Schwabe, PhD, Chioma Madubata, Raul Rabadan, Adolfo A. Ferrando, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2602.
https://doi.org/10.1182/blood.V130.Suppl_1.2602.2602
Published: 2017
Journal Articles

RARB Translocations in Acute Promyelocytic Leukemia without Rara translocation

Motohiro Kato, MD, Tomoo Osumi, MD, Shinichi Tsujimoto, MD, Moe Tamura, Meri Uchiyama, Kazuhiko Nakabayashi, Kohji Okamura, Daisuke Tomizawa, MD PhD, Akihiro Watanabe, Hiroyuki Takahashi, Tsukasa Hori, MD PhD, Shohei Yamamoto, MD PhD, Kazuko Hamamoto, Masahiro Migita, Hiroko Ogata-Kawata, Toru Uchiyama, Hiroe Kizawa, Hitomi Ueno-Yokohata, Ryota Shirai, Masanori Yoshida, Masafumi Seki, MD,PhD, Kentaro Oki, MD PhD, Junko Takita, MD PhD, Seishi Ogawa, MD PhD, Toshio Kitamura, MD PhD, Kimikazu Matsumoto, Kenichiro Hata, MD PhD, Susumu Goyama, MD PhD, Nobutaka Kiyokawa, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 104.
https://doi.org/10.1182/blood.V130.Suppl_1.104.104
Published: 2017