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Journal Articles

Chemotherapy with the Use of TKIs Based on MRD Has the Potential to Avoid Hematopoietic Stem Cell Transplantation in Treatment for Children with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ALL). Results of the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) Study ALL-Ph13

Atsushi Sato, Hirohide Kawasaki, Takao Deguchi, Yoshiko Hashii, Yuka Iijima-Yamashita, Sachiko Yonezawa, Chiyo K Imamura, Haruko Shima, Hirotoshi Sakaguchi, Yuichi Kodama, Keisuke Kato, Motohiro Kato, Hidefumi Hiramatsu, Nobutaka Kiyokawa, Akiko Kada, Akiko M Saito, Keizo Horibe, Atsushi Manabe, Hiroyuki Shimada

Blood (2021) 138 (Supplement 1): 3394.

https://doi.org/10.1182/blood-2021-148264

Published: 2021

Journal Articles

A Multicenter, Prospective Study for Pediatric Chronic Myeloid Leukemia in Chronic Phase: The JPLSG CML-08 Study

Hiroyuki Shimada, Akihiro Watanabe, Masaki Ito, Chikako Tono, Haruko Shima, Yuki Yuza, Hideki Muramatsu, Masahiko Okada, Akihiko Tanizawa

Blood (2021) 138 (Supplement 1): 3605.

https://doi.org/10.1182/blood-2021-154335

Published: 2021

Journal Articles

Phase 2 study of nilotinib in pediatric patients with Philadelphia chromosome–positive chronic myeloid leukemia

Blood (2019) 134 (23): 2036–2045.

https://doi.org/10.1182/blood.2019000069

Published: 2019

Includes: Supplemental data

Journal Articles

Discontinuation of Tyrosine Kinase Inhibitor in Children with Chronic Myeloid Leukemia (JPLSG STKI-14 study)

Haruko Shima, MD PhD, Akiko Kada, MPH, Akihiko Tanizawa, MD PhD, Yuki Yuza, MD PhD, Akihiro Watanabe, Masaki Ito, MD, Hideko Uryu, Katsuyoshi Koh, MD, Chihaya Imai, MD PhD, Nao Yoshida, MD PhD, Yuhki Koga, MD, Naoto Fujita, MD PhD, Akiko M Saito, MD PhD, Souichi Adachi, MD PhD, Eiichi Ishii, MD PhD, Hiroyuki Shimada, MD PhD

Blood (2019) 134 (Supplement_1): 25.

https://doi.org/10.1182/blood-2019-122623

Published: 2019

Journal Articles

Reduced-Intensity Allogeneic HSCT for Children and Adolescents/Young Adults with CML: A Study from the Adult and Pediatric CML Working Group of the Japan Society for Hematopoietic Cell Transplantation

Hiroyuki Shimada, MD PhD, Akihiko Tanizawa, MD PhD, Takeshi Kondo, MD PhD, Hideki Muramatsu, MD PhD, Masahiro Yasui, MD, Arinobu Tojo, MD PhD, Tokiko Nagamura-Inoue, MD PhD, Tetsuya Eto, MD PhD, Aiko Igarashi, MD, Heiwa Kanamori, MD PhD, Maho Sato, MD, Maiko Noguchi, MD, Tatsuo Ichinohe, MD PhD, Masami Inoue, MD, Koji Kato, MD PhD, Yoshiko Atsuta, MD PhD, Kazuteru Ohashi, MD PhD

Blood (2018) 132 (Supplement 1): 3008.

https://doi.org/10.1182/blood-2018-99-117836

Published: 2018

Journal Articles

Interim Analysis of a Multicenter, Prospective Study for Pediatric Chronic Myeloid Leukemia in Chronic Phase: The JPLSG CML-08 Study

Hiroyuki Shimada, MD PhD, Hidemitsu Kurosawa, MD, Akihiro Watanabe, Masaki Ito, Chikako Tono, Haruko Shima, MD PhD, Yuki Yuza, MD PhD, Hideki Muramatsu, MD PhD, Noriko Hotta, Masahiko Okada, Akihiko Tanizawa

Blood (2015) 126 (23): 2782.

https://doi.org/10.1182/blood.V126.23.2782.2782

Published: 2015

Journal Articles

Spontaneous Alleviation Of Growth Impairment In Tyrosine Kinase Inhibitor-Treated Chronic Myeloid Leukemia Children

Haruko Shima, MD, PhD, Akihiko Tanizawa, Chikako Tono, Akihiro Watanabe, MD, Hidemitsu Kurosawa, MD, Masaki Ito, MD, PhD, Yuki Yuza, MD, Noriko Hotta, Hideki Muramatsu, MD, PhD, Masahiko Okada, Mika Tokuyama, Koji Kato, MD, Katsuyoshi Koh, MD, PhD, Akiko M. Saito, MD, PhD, Souichi Adachi, MD, PhD, Keizo Horibe, MD, PhD, Shuki Mizutani, MD, PhD, Hiroyuki Shimada, MD, PhD

Blood (2013) 122 (21): 3999.

https://doi.org/10.1182/blood.V122.21.3999.3999

Published: 2013

Journal Articles

Integrin alpha4 blockade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy

Blood (2013) 121 (10): 1814–1818.

https://doi.org/10.1182/blood-2012-01-406272

Published: 2013

Includes: Supplemental data

Journal Articles

Retinoid agonist Am80-enhanced neutrophil bactericidal activity arising from granulopoiesis in vitro and in a neutropenic mouse model

Wanjing Ding, Hiroyuki Shimada, Lin Li, Rahul Mittal, Xiaokun Zhang, Koichi Shudo, Qiaojun He, Nemani V. Prasadarao, Lingtao Wu

Blood (2013) 121 (6): 996–1007.

https://doi.org/10.1182/blood-2012-06-436022

Published: 2013

Includes: Supplemental data

Journal Articles

A Brief Use of Imatinib Immediately Before Hematopoietic Stem Cell Transplantation (HSCT) in Children with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ALL). Results of the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) Study Ph+ALL04

Atsushi Manabe, Hirohide Kawasaki, MD, PhD, Motoaki Chin, MD, Atsushi Sato, MD, PhD, Kimikazu Matsumoto, MD, Tsutomu Watanabe, MD, Michiko Kajiwara, MD, PhD, Hiroyuki Shimada, MD, PhD, Itaru Kato, MD, Yuichi Kodama, MD, Noriko Sato, MD, Kazuko Kudo, MD, PhD, Atsushi Kikuta, MD, PhD, Megumi Oda, MD, PhD, Tomoyuki Watanabe, PhD, Akiko M. Saito, MD, PhD, Masahito Tsurusawa, MD, PhD, Keizo Horibe, MD, PhD

Blood (2011) 118 (21): 2554.

https://doi.org/10.1182/blood.V118.21.2554.2554

Published: 2011

Journal Articles

Distinct Impact of Imatinib on Growth In Prepubertal and Pubertal Children with Chronic Myeloid Leukemia

Haruko Shima, MD, PhD, Mika Tokuyama, Akihiko Tanizawa, Chikako Tono, Kazuko Hamamoto, Hideki Muramatsu, Akihiro Watanabe, Noriko Hotta, Masaki Ito, Hidemitsu Kurosawa, MD, Koji Kato, MD, PhD, Masahito Tsurusawa, MD, Keizo Horibe, MD, PhD, Hiroyuki Shimada

Blood (2010) 116 (21): 2277.

https://doi.org/10.1182/blood.V116.21.2277.2277

Published: 2010

Journal Articles

Adjuvant CD49d Blockade Eradicates Chemoresistant ALL

Yao-Te Hsieh, Eugene Park, Enzi Jiang, MD, PhD, Katrin Dauber, Doreen Chudziak, Paul Schaefer, Lars Klemm, Carlton Scharman, Eun-Suk Kang, MD, PhD, Hong-Hoe Koo, MD, PhD, Mignon L. Loh, M.D., Wolf Karsten Hofmann, MD, PhD, Nora Heisterkamp, Markus Muschen, MD, Hiroyuki Shimada, MD, Halvard Bonig, MD, MA, Yong-Mi Kim, MD, MPH

Blood (2010) 116 (21): 869.

https://doi.org/10.1182/blood.V116.21.869.869

Published: 2010

Journal Articles

Unrelated Bone Marrow Transplantation for Children with Chronic Myeloid Leukemia (CML): A Report from the Japan Marrow Donor Program (JMDP).

Hideki Muramatsu, Seiji Kojima, Ayami Yoshimi, Yoshiko Atsuta, Chikako Tono, Koji Kato, Yoshihisa Nagatoshi, Masami Inoue, Kazutoshi Koike, Takakazu Kawase, Keisei Kawa, Hiroyuki Shimada

Blood (2008) 112 (11): 971.

https://doi.org/10.1182/blood.V112.11.971.971

Published: 2008

Journal Articles

Endothelial apoptosis induced by inhibition of integrins αvβ3 and αvβ5 involves ceramide metabolic pathways

Anat Erdreich-Epstein, Linda B. Tran, Órla T. Cox, Elaine Y. Huang, Walter E. Laug, Hiroyuki Shimada, Melissa Millard

Blood (2005) 105 (11): 4353–4361.

https://doi.org/10.1182/blood-2004-08-3098

Published: 2005

Journal Articles

Antidisialoganglioside/granulocyte macrophage–colony-stimulating factor fusion protein facilitates neutrophil antibody-dependent cellular cytotoxicity and depends on FcγRII (CD32) and Mac-1 (CD11b/CD18) for enhanced effector cell adhesion and azurophil granule exocytosis

Leonid S. Metelitsa, Stephen D. Gillies, Michael Super, Hiroyuki Shimada, C. Patrick Reynolds, Robert C. Seeger

Blood (2002) 99 (11): 4166–4173.

https://doi.org/10.1182/blood.V99.11.4166

Published: 2002

Journal Articles

Analysis of genes under the downstream control of the t(8;21) fusion protein AML1-MTG8: overexpression of the TIS11b ( ERF-1 , cMG1 ) gene induces myeloid cell proliferation in response to G-CSF

Hiroyuki Shimada, Hitoshi Ichikawa, Sawako Nakamura, Rieko Katsu, Mitsuteru Iwasa, Issay Kitabayashi, Misao Ohki

Blood (2000) 96 (2): 655–663.

https://doi.org/10.1182/blood.V96.2.655

Published: 2000

NARROW

A Multicenter, Prospective Study for Pediatric Chronic Myeloid Leukemia in Chronic Phase: The JPLSG CML-08 Study

Phase 2 study of nilotinib in pediatric patients with Philadelphia chromosome–positive chronic myeloid leukemia

Discontinuation of Tyrosine Kinase Inhibitor in Children with Chronic Myeloid Leukemia (JPLSG STKI-14 study)

Reduced-Intensity Allogeneic HSCT for Children and Adolescents/Young Adults with CML: A Study from the Adult and Pediatric CML Working Group of the Japan Society for Hematopoietic Cell Transplantation

Interim Analysis of a Multicenter, Prospective Study for Pediatric Chronic Myeloid Leukemia in Chronic Phase: The JPLSG CML-08 Study

Spontaneous Alleviation Of Growth Impairment In Tyrosine Kinase Inhibitor-Treated Chronic Myeloid Leukemia Children

Integrin alpha4 blockade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy

Retinoid agonist Am80-enhanced neutrophil bactericidal activity arising from granulopoiesis in vitro and in a neutropenic mouse model

A Brief Use of Imatinib Immediately Before Hematopoietic Stem Cell Transplantation (HSCT) in Children with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ALL). Results of the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) Study Ph+ALL04

Distinct Impact of Imatinib on Growth In Prepubertal and Pubertal Children with Chronic Myeloid Leukemia

Adjuvant CD49d Blockade Eradicates Chemoresistant ALL

Unrelated Bone Marrow Transplantation for Children with Chronic Myeloid Leukemia (CML): A Report from the Japan Marrow Donor Program (JMDP).

Endothelial apoptosis induced by inhibition of integrins αvβ3 and αvβ5 involves ceramide metabolic pathways

Antidisialoganglioside/granulocyte macrophage–colony-stimulating factor fusion protein facilitates neutrophil antibody-dependent cellular cytotoxicity and depends on FcγRII (CD32) and Mac-1 (CD11b/CD18) for enhanced effector cell adhesion and azurophil granule exocytosis

Analysis of genes under the downstream control of the t(8;21) fusion protein AML1-MTG8: overexpression of the TIS11b ( ERF-1 , cMG1 ) gene induces myeloid cell proliferation in response to G-CSF

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American Society of Hematology

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American Society of Hematology

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