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Journal Articles

Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia

Kazunari Aoki, Mizuki Hyuga, Yusuke Tarumoto, Gohei Nishibuchi, Atsushi Ueda, Yotaro Ochi, Seiichi Sugino, Takashi Mikami, Hirokazu Kobushi, Itaru Kato, Koshi Akahane, Takeshi Inukai, Akifumi Takaori-Kondo, Junko Takita, Seishi Ogawa, Kosuke Yusa

Blood (2024) 143 (7): 604–618.

https://doi.org/10.1182/blood.2023020857

Published: 2024

Includes: Supplemental data

Journal Articles

STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young

Shunsuke Kimura, Petri Pölönen, Lindsey Montefiori, Kenneth Caldwell, Ilaria Iacobucci, Chelsey Chen, Anthony Brown, Katie Han, Yen-Chun Liu, Yunchao Chang, Zhongshan Cheng, Zhou Yinmei, Chun Shik Park, Sharnise Mitchell, Noemi Reyes, Allen Yeoh, Andishe Attarbaschi, Andrew Moore, Atsushi Manabe, Barbara Buldini, Kean Hui Chiew, Chi Kong Li, Ching-Hon Pui, Chunxu Qu, Daisuke Tomizawa, Elisabeth Paietta, Franco Locatelli, Gabriele Escherich, Gao Qingsong, Hannah Elisa Muhle, Hanne Vibeke Marquart, Hester A. de Groot-Kruseman, Jacob M. Rowe, Jan Stary, Jan Trka, John Kim Choi, Jules P.P. Meijerink, Junko Takita, Katarzyna Pawinska-Wasikowska, Kjeld Schmiegelow, Mariko Eguchi, Martin Schrappe, Martin Zimmermann, Masatoshi Takagi, Melissa Maybury, Michael Svaton, Michaela Reiterova, Michal Kicinski, Motohiro Kato, Orietta Spinelli, Pauline Mazilier, Paul G. Thomas, Riccardo Masetti, Rishi Sury Kotecha, Rob Pieters, Sarah Elitzur, Selina M Luger, Shuhong Shen, Sima Jeha, Steven M. Kornblau, Szymon Skoczen, Takako Miyamura, Tiffaney Vincent, Toshihiko Imamura, Valentino Conter, Yanjing Tang, Zhaohui Gu, Kathryn G. Roberts, David T. Teachey, Kristine R Crews, Cheng Cheng, Jun J. Yang, Hiroto Inaba, Charles G. Mullighan

Blood (2023) 142 (Supplement 1): 845.

https://doi.org/10.1182/blood-2023-178688

Published: 2023

Journal Articles

Higher CD34+ Cell Doses Correlate with Reduced Incidence of Relapse and Better Event-Free Survival after KIR-Ligand Mismatch Cord Blood Transplantation for Childhood Acute Myeloid Leukemia

Hisashi Ishida, Yuta Kawahara, Daisuke Tomizawa, Yasuhiro Okamoto, Yuko Cho, Katsuyoshi Koh, Yuhki Koga, Asahito Hama, Maho Sato, Kiminori Terui, Naoyuki Miyagawa, Akihiro Watanabe, Junko Takita, Koji Kato, Kimikazu Matsumoto, Moeko Hino, Ken Tabuchi, Hirotoshi Sakaguchi

Blood (2023) 142 (Supplement 1): 2843.

https://doi.org/10.1182/blood-2023-174310

Published: 2023

Journal Articles

Integrated Analysis of KIT Exon 17 Mutations and Flow-MRD Refines Risk Stratification in Pediatric Acute Myeloid Leukemia with RUNX1 :: RUNX1T1

Shin-Ichi Tsujimoto, Shota Kato, Shotaro Iwamoto, Hidefumi Hiramatsu, Yusuke Okuno, Tatsuya Kamitori, Kentaro Ohki, Takao Deguchi, Nobutaka Kiyokawa, Motohiro Kato, Junko Takita, Souichi Adachi, Daisuke Tomizawa, Norio Shiba

Blood (2023) 142 (Supplement 1): 1599.

https://doi.org/10.1182/blood-2023-181358

Published: 2023

Journal Articles

Prognostic Factors in Children with Acute Myeloid Leukemia Receiving the First Hematopoietic Stem Cell Transplantation in Second Remission

Blood (2022) 140 (Supplement 1): 6075–6076.

https://doi.org/10.1182/blood-2022-158712

Published: 2022

Journal Articles

Clinical Significance of IGH Clonality Analysis with RNA Sequencing in B-Cell Precursor Acute Lymphoblastic Leukemia

Yuta Katai, Tatsuya Kamitori, Hiroo Ueno, Ryo Akazawa, Kiyotaka Isobe, Itaru Kato, Toshihiko Imamura, Katsuyoshi Koh, Satoshi Saida, Junko Takita

Blood (2022) 140 (Supplement 1): 9187–9188.

https://doi.org/10.1182/blood-2022-164512

Published: 2022

Journal Articles

Clonal Evolution Pattern and Prognostic Significance of Clonal Architecture in KMT2A -Rearranged Acute Myeloid Leukemia

Blood (2021) 138 (Supplement 1): 2358.

https://doi.org/10.1182/blood-2021-146699

Published: 2021

Journal Articles

Mass Cytometric Analysis Revealed Dynamic Alteration of the Tumor Immune Environment in Bone Marrow from Children with Recurrent B Cell Precursor Acute Lymphoblastic Leukemia

Blood (2021) 138 (Supplement 1): 2390.

https://doi.org/10.1182/blood-2021-146420

Published: 2021

Journal Articles

Activation of the STAT1-BCL-2/MCL-1 Axis in Leukemic Cells Carrying a SPAG9-JAK2 Fusion

Azusa Mayumi, Toshihiro Tomii, Takuyo Kanayama, Takashi Mikami, Kuniaki Tanaka, Hideki Yoshida, Itaru Kato, Machiko Kawamura, Tatsutoshi Nakahata, Junko Takita, Hajime Hosoi, Toshihiko Imamura

Blood (2021) 138 (Supplement 1): 4326.

https://doi.org/10.1182/blood-2021-149153

Published: 2021

Journal Articles

Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL

Blood (2020) 136 (20): 2319–2333.

https://doi.org/10.1182/blood.2019004090

Published: 2020

Includes: Supplemental data

Journal Articles

CBFA2T3-GLIS2 Fusion Gene Cause Dismal Clinical Course in Acute Megakaryocytic Leukemia of Down Syndrome

Nao Takasugi, Kenichi Amano, Yasuo Kubota, MD, Shota Kato, MD, Yuichi Mitani, MD, Junya Fujimura, MD PhD, Junko Takita, MD PhD, Mitsuteru Hiwatari, MD PhD

Blood (2019) 134 (Supplement_1): 5184.

https://doi.org/10.1182/blood-2019-129165

Published: 2019

Journal Articles

Brefeldin Α Reduces STAT3 Dependent Survival of Acute Leukemia and Neuroblastoma Cells

Mitsuteru Hiwatari, MD PhD, Kentaro Watanabe, MD, Yasuo Kubota, MD, Masahiro Sekiguchi, MD, Junko Takita, MD PhD

Blood (2019) 134 (Supplement_1): 5762.

https://doi.org/10.1182/blood-2019-130056

Published: 2019

Journal Articles

Therapeutic Targeting of RUNX-NFATC2 Axis for Acute Promyelocytic Leukemia and T Cell Immunity

Hirohito Kubota, MD, Kana Furuichi, Tatsuya Masuda, Toshiya Tatsuta, Hidefumi Hiramatsu, MD PhD, Junko Takita, MD PhD, Sugiyama Hiroshi, PhD, Souichi Adachi, MD PhD, Yasuhiko Kamikubo, MD, PhD

Blood (2019) 134 (Supplement_1): 3359.

https://doi.org/10.1182/blood-2019-126428

Published: 2019

Journal Articles

Leukemic Cell Expressing a Novel Kinase Fusion Protein NCOR1-LYN Exhibits High Sensitivity to Dasatinib and Rapamycin

Toshihiro Tomii, MD, Toshihiko Imamura, MD PhD, Mio Yano, MD, Kenichi Sakamoto, MD PhD, Itaru Kato, Kuniaki Tanaka, MD, Takashi Mikami, MD, Makiko Morita, PhD, Souichi Adachi, MD PhD, Junko Takita, MD, PhD, Nobutaka Kiyokawa, MD PhD, Keizo Horibe, MD PhD, Hajime Hosoi, MD PhD

Blood (2018) 132 (Supplement 1): 1557.

https://doi.org/10.1182/blood-2018-99-111612

Published: 2018

Journal Articles

Piggybac CD19 CAR T Cells Eradicate CNS Leukemia By Direct Delivery into Cerebral Ventricle of Xenograft Mice Model

Kuniaki Tanaka, MD, Itaru Kato, MD, PhD, Miyuki Tanaka, MD, PhD, Daisuke Morita, MD, PhD, Yoshiyuki Takahashi, MD, PhD, Tatsutoshi Nakahata, MD, PhD, Katsutsugu Umeda, MD, PhD, Hidefumi Hiramatsu, MD, PhD, Souichi Adachi, MD PhD, Junko Takita, MD, PhD, Yozo Nakazawa, MD, PhD

Blood (2018) 132 (Supplement 1): 4028.

https://doi.org/10.1182/blood-2018-99-111733

Published: 2018

Journal Articles

The Prognostic Value of TP53 Mutations Depends on Clinical Backgrounds in Pediatric Patients with Acute Lymphoblastic Leukemia

Blood (2018) 132 (Supplement 1): 4077.

https://doi.org/10.1182/blood-2018-99-115617

Published: 2018

Journal Articles

Distribution and Clinical Features of NOTCH1 Signaling Activating Alterations in Pediatric T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Blood (2018) 132 (Supplement 1): 4089.

https://doi.org/10.1182/blood-2018-99-111092

Published: 2018

Journal Articles

Comprehensive Genomic Analysis Identified Acute Lymphoblastic Leukemia in Down Syndrome Was Highly Heterogeneous with the High Prevalence of Ph-like Signature

Yasuo Kubota, MD, Kumiko Uryu, MD PhD, Tatsuya Ito, MD, Masafumi Seki, MD,PhD, Tomoya Isobe, MD, Tsutomu Toki, PhD, Kenichi Yoshida, MD PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, PhD, Hiroko Tanaka, BA, MItsuteru Hiwatari, MD PhD, Satoru Miyano, PhD, Akira Oka, MD PhD, Seishi Ogawa, MD PhD, Kiminori Terui, MD PhD, Atsushi Sato, MD, Etsuro Ito, MD PhD, Junko Takita, MD PhD

Blood (2018) 132 (Supplement 1): 2817.

https://doi.org/10.1182/blood-2018-99-111080

Published: 2018

Journal Articles

Identification of Novel Pathways and Small Molecules Able to Down Regulate Oncogenes Expression By Compounds Screening Approaches in Acute Leukemia and Neuroblastoma Cells

Mitsuteru Hiwatari, MD PhD, Kentaro Watanabe, MD, Yasuo Kubota, MD, Shunsuke Kimura, MD, Junko Takita, MD, PhD

Blood (2018) 132 (Supplement 1): 2214.

https://doi.org/10.1182/blood-2018-99-111090

Published: 2018

Journal Articles

Integrated Genetic/Epigenetic Analysis Revealed High Heterogeneity of Acute Lymphoblastic Leukemia in Down Syndrome

Blood (2017) 130 (Supplement 1): 3975.

https://doi.org/10.1182/blood.V130.Suppl_1.3975.3975

Published: 2017

NARROW

Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia

STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young

Higher CD34+ Cell Doses Correlate with Reduced Incidence of Relapse and Better Event-Free Survival after KIR-Ligand Mismatch Cord Blood Transplantation for Childhood Acute Myeloid Leukemia

Integrated Analysis of KIT Exon 17 Mutations and Flow-MRD Refines Risk Stratification in Pediatric Acute Myeloid Leukemia with RUNX1 :: RUNX1T1

Prognostic Factors in Children with Acute Myeloid Leukemia Receiving the First Hematopoietic Stem Cell Transplantation in Second Remission

Clinical Significance of IGH Clonality Analysis with RNA Sequencing in B-Cell Precursor Acute Lymphoblastic Leukemia

Clonal Evolution Pattern and Prognostic Significance of Clonal Architecture in KMT2A -Rearranged Acute Myeloid Leukemia

Mass Cytometric Analysis Revealed Dynamic Alteration of the Tumor Immune Environment in Bone Marrow from Children with Recurrent B Cell Precursor Acute Lymphoblastic Leukemia

Activation of the STAT1-BCL-2/MCL-1 Axis in Leukemic Cells Carrying a SPAG9-JAK2 Fusion

Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL

CBFA2T3-GLIS2 Fusion Gene Cause Dismal Clinical Course in Acute Megakaryocytic Leukemia of Down Syndrome

Brefeldin Α Reduces STAT3 Dependent Survival of Acute Leukemia and Neuroblastoma Cells

Therapeutic Targeting of RUNX-NFATC2 Axis for Acute Promyelocytic Leukemia and T Cell Immunity

Leukemic Cell Expressing a Novel Kinase Fusion Protein NCOR1-LYN Exhibits High Sensitivity to Dasatinib and Rapamycin

Piggybac CD19 CAR T Cells Eradicate CNS Leukemia By Direct Delivery into Cerebral Ventricle of Xenograft Mice Model

The Prognostic Value of TP53 Mutations Depends on Clinical Backgrounds in Pediatric Patients with Acute Lymphoblastic Leukemia

Distribution and Clinical Features of NOTCH1 Signaling Activating Alterations in Pediatric T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Comprehensive Genomic Analysis Identified Acute Lymphoblastic Leukemia in Down Syndrome Was Highly Heterogeneous with the High Prevalence of Ph-like Signature

Identification of Novel Pathways and Small Molecules Able to Down Regulate Oncogenes Expression By Compounds Screening Approaches in Acute Leukemia and Neuroblastoma Cells

Integrated Genetic/Epigenetic Analysis Revealed High Heterogeneity of Acute Lymphoblastic Leukemia in Down Syndrome

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American Society of Hematology

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American Society of Hematology

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