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Journal Articles

UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genes

Blood (2021) 137 (7): 908–922.

https://doi.org/10.1182/blood.2019001044

Published: 2021

Includes: Supplemental data

Journal Articles

Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL

Blood (2020) 136 (20): 2319–2333.

https://doi.org/10.1182/blood.2019004090

Published: 2020

Includes: Supplemental data

Journal Articles

Acquired expression of Cbl Q367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia

Yuichiro Nakata, Takeshi Ueda, Akiko Nagamachi, Norimasa Yamasaki, Ken-ichiro Ikeda, Yasuyuki Sera, Keiyo Takubo, Akinori Kanai, Hideaki Oda, Masashi Sanada, Seishi Ogawa, Kohichiro Tsuji, Yasuhiro Ebihara, Linda Wolff, Zen-ichiro Honda, Toshio Suda, Toshiya Inaba, Hiroaki Honda

Blood (2017) 129 (15): 2148–2160.

https://doi.org/10.1182/blood-2016-06-724658

Published: 2017

Includes: Supplemental data

Journal Articles

JMJD3 Plays Essential Roles in the Maintenance of Hematopoietic Stem Cells and Leukemic Stem Cells through the Regulation of p16 INK4a

Yuichiro Nakata, PhD, Norimasa Yamasaki, Takeshi Ueda, MD, PhD, Kenichiro Ikeda, MD, Akiko Nagamachi, PhD, Toshiya Inaba, MD, PhD, Hiroaki Honda, MD, PhD

Blood (2016) 128 (22): 2653.

https://doi.org/10.1182/blood.V128.22.2653.2653

Published: 2016

Journal Articles

Low Miki Expression in Myelodysplastic Syndromes Results in Polynuclear Cell Formation through Decondensation of Chromosomes in Prolonged Prometaphase

Akiko Nagamachi, PhD, Yuko Ozaki, PhD, Hirotaka Matsui, MD PhD, Akinori Kanai, PhD, Toshiya Inaba, MD

Blood (2015) 126 (23): 2845.

https://doi.org/10.1182/blood.V126.23.2845.2845

Published: 2015

Journal Articles

Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2

Takeshi Ueda, Akiko Nagamachi, Keiyo Takubo, Norimasa Yamasaki, Hirotaka Matsui, Akinori Kanai, Yuichiro Nakata, Kenichiro Ikeda, Takaaki Konuma, Hideaki Oda, Linda Wolff, Zen-ichiro Honda, Xudong Wu, Kristian Helin, Atsushi Iwama, Toshio Suda, Toshiya Inaba, Hiroaki Honda

Blood (2015) 125 (22): 3437–3446.

https://doi.org/10.1182/blood-2014-03-562694

Published: 2015

Includes: Supplemental data

Journal Articles

Generation and Analysis of a Novel Mouse Model for Chronic Myelomonocytic Leukemia (CMML) with Acquired Expression of c-CBL Q367P

Yuichiro Nakata, Takeshi Ueda, MD PhD, Akiko Nagamachi, PhD, Linda Wolff, PhD, Ogawa Seishi, MD, Toshiya Inaba, MD, Hiroaki Honda, MD PhD

Blood (2014) 124 (21): 4602.

https://doi.org/10.1182/blood.V124.21.4602.4602

Published: 2014

Journal Articles

SETBP1 Mutations Drive Leukemic Transformation in ASXL1 -Mutated MDS

Daichi Inoue, MD PhD, Hirotaka Matsui, MD PhD, Hsin-An Hou, MD PhD, Wen-Chien Chou, MD PhD, Akiko Nagamachi, PhD, Jiro Kitaura, MD PhD, Kimihito Cojin Kawabata, MD PhD, Katsuhiro Togami, MD PhD, Reina Nagase, Sayuri Horikawa, Makoto Saika, MD, Jean-Baptiste Micol, MD, Yasutaka Hayashi, MD, Yuka Harada, MD PhD, Hironori Harada, MD PhD, Hwei-Fang Tien, MD PhD, Omar Abdel-Wahab, MD, Toshio Kitamura, MD PhD

Blood (2014) 124 (21): 525.

https://doi.org/10.1182/blood.V124.21.525.525

Published: 2014

Journal Articles

Haploinsufficiency Of SAMD9L , An Endosome Fusion Facilitator, In Mice Induces The Development Of Myeloid Malignancies Mimicking Human Diseases With Monosomy 7

Hirotaka Matsui, MD, PhD, Akiko Nagamachi, Akinori Kanai, PhD, Yuko Ozaki, Hiroaki Honda, MD, PhD, Toshiya Inaba, MD, PhD

Blood (2013) 122 (21): 227.

https://doi.org/10.1182/blood.V122.21.227.227

Published: 2013

Journal Articles

Abnormal Mitosis Due to Impairment of Centrosome Maturation by the Deletion of Candidate 7q- Responsible Genes

Hirotaka Matsui, MD, Yuko Ozaki, Akiko Nagamachi, Toshiya Inaba, MD, PhD

Blood (2012) 120 (21): 1297.

https://doi.org/10.1182/blood.V120.21.1297.1297

Published: 2012

Journal Articles

Samd9L-Deficient Mice Develop Myeloid Malignancies Mimicking Human Diseases with Monosomy 7

Hirotaka Matsui, MD, Akiko Nagamachi, Yuko Ozaki, Hiroya Asou, MD, PhD, Hiroaki Honda, MD, PhD, Toshiya Inaba, MD, PhD

Blood (2011) 118 (21): 869.

https://doi.org/10.1182/blood.V118.21.869.869

Published: 2011

Journal Articles

Titan (Samd9L), a Candidate -7/7q- Responsible Gene Product, Downregulates Cytokine Signals by Facilitating Formation of Early Endosomes

Hirotaka Matsui, MD, Akiko Nagamachi, Yuko Ozaki, Hiroya Asou, MD, Hiroaki Honda, MD, Toshiya Inaba, MD

Blood (2010) 116 (21): 4170.

https://doi.org/10.1182/blood.V116.21.4170.4170

Published: 2010

Journal Articles

Loss of Titan ( Samd9L ), a Candidate -7/7q- Responsible Gene Encoding An Actin Remodeling Regulator, Develops MDS/AML in Cooperation with Evi1 or Fbxl10 .

Hirotaka Matsui, MD, Akiko Nagamachi, Yuko Ozaki, Daisuke Aki, Hiroya Asou, MD, Hiroaki Honda, MD, Toshiya Inaba, MD

Blood (2009) 114 (22): 2963.

https://doi.org/10.1182/blood.V114.22.2963.2963

Published: 2009

Journal Articles

Haploinsufficiency and Deficiency of a 7q Gene Titan (Samd9L) Predispose Leukemia Development in Cooperation with Deregulated Expression of a Transcription Factor, Evi1, or a Histone Demethylase, Fbxl10

Akiko Nagamachi, Hiroya Asou, MD, Hirotaka Matsui, MD, Yuko Ozaki, Daisuke Aki, PhD, Kazuko Miyazaki, Norimasa Yamasaki, Masaki Miyazaki, MD, Linda Wolff, PhD, Richard Koller, Hideaki Oda, MD, Toshiya Inaba, MD, Hiroaki Honda, MD

Blood (2008) 112 (11): 197.

https://doi.org/10.1182/blood.V112.11.197.197

Published: 2008

Journal Articles

Identification of Two 7q Genes Encoding Centrosomal Proteins as Myeloid Tumor-Suppressor Candidates.

Hiroya Asou, Yuko Ozaki, Akiko Nagamachi, Daisuke Aki, Hirotaka Matsui, Toshiya Inaba, MD

Blood (2008) 112 (11): 1793.

https://doi.org/10.1182/blood.V112.11.1793.1793

Published: 2008

Journal Articles

Downregulation of a Candidate Myeloid Tumor Suppressor Gene Isolated from 7q21 Induces Abnormal Mitosis Due to Insufficient Centrosome Maturation.

Hiroya Asou, MD, Hirotaka Matsui, MD, Yuko Ozaki, Akiko Nagamachi, Daisuke Aki, PhD, Miho Ohsugi, PhD, Toshiya Inaba, MD

Blood (2007) 110 (11): 2638.

https://doi.org/10.1182/blood.V110.11.2638.2638

Published: 2007

Journal Articles

Abnormal Mitosis and Genetic Instability Induced by Downregulation of Candidate Myeloid Tumor Suppressor Genes Isolated from the Long Arm of Chromosome 7.

Hiroya Asou, MD, Hirotaka Matsui, M.D., Yuko Ozaki, Toshiyuki Takemura, Ph.D., Akiko Nagamachi, Daisuke Aki, Ph.D., Miho Ohsugi, Ph.D., Toshiya Inaba, M.D.

Blood (2006) 108 (11): 390.

https://doi.org/10.1182/blood.V108.11.390.390

Published: 2006

NARROW

UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genes

Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL

Acquired expression of Cbl Q367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia

JMJD3 Plays Essential Roles in the Maintenance of Hematopoietic Stem Cells and Leukemic Stem Cells through the Regulation of p16 INK4a

Low Miki Expression in Myelodysplastic Syndromes Results in Polynuclear Cell Formation through Decondensation of Chromosomes in Prolonged Prometaphase

Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2

Generation and Analysis of a Novel Mouse Model for Chronic Myelomonocytic Leukemia (CMML) with Acquired Expression of c-CBL Q367P

SETBP1 Mutations Drive Leukemic Transformation in ASXL1 -Mutated MDS

Haploinsufficiency Of SAMD9L , An Endosome Fusion Facilitator, In Mice Induces The Development Of Myeloid Malignancies Mimicking Human Diseases With Monosomy 7

Abnormal Mitosis Due to Impairment of Centrosome Maturation by the Deletion of Candidate 7q- Responsible Genes

Samd9L-Deficient Mice Develop Myeloid Malignancies Mimicking Human Diseases with Monosomy 7

Titan (Samd9L), a Candidate -7/7q- Responsible Gene Product, Downregulates Cytokine Signals by Facilitating Formation of Early Endosomes

Loss of Titan ( Samd9L ), a Candidate -7/7q- Responsible Gene Encoding An Actin Remodeling Regulator, Develops MDS/AML in Cooperation with Evi1 or Fbxl10 .

Haploinsufficiency and Deficiency of a 7q Gene Titan (Samd9L) Predispose Leukemia Development in Cooperation with Deregulated Expression of a Transcription Factor, Evi1, or a Histone Demethylase, Fbxl10

Identification of Two 7q Genes Encoding Centrosomal Proteins as Myeloid Tumor-Suppressor Candidates.

Downregulation of a Candidate Myeloid Tumor Suppressor Gene Isolated from 7q21 Induces Abnormal Mitosis Due to Insufficient Centrosome Maturation.

Abnormal Mitosis and Genetic Instability Induced by Downregulation of Candidate Myeloid Tumor Suppressor Genes Isolated from the Long Arm of Chromosome 7.

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American Society of Hematology

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American Society of Hematology

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