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Journal Articles

Deep Sequencing Is a Widely Applicable Tool for Relapse Prediction in Acute Myeloid Leukemia with Mutated NPM1

Sofie Johansson Alm, Gustav Orrsjö, Giti Shah Barkhordar, Anna Rehammar, Erik Delsing Malmberg, Per-Ola Andersson, Mats L. Brune, Hege Kristin Gravdahl Garelius, Mats Hardling, Lars Palmqvist, Linda Fogelstrand

Blood (2023) 142 (Supplement 1): 2963.

https://doi.org/10.1182/blood-2023-173497

Published: 2023

Journal Articles

Nucleophosmin (NPM1) Type D Genotype Is Associated with Distinct Outcome in Acute Myeloid Leukemia - an AIEOP-BFM and COG-SWOG Intergroup Collaboration

Martina Pigazzi, Claudia Tregnago, Rhonda E Ries, Maddalena Benetton, Todd A. Alonzo, Nicolas Duployez, Edwin Sonneveld, Jonas Abrahamsson, Linda Fogelstrand, Nils Von Neuhoff, Henrik Hasle, Dirk Reinhardt, Franco Locatelli, Soheil Meshinchi

Blood (2023) 142 (Supplement 1): 840.

https://doi.org/10.1182/blood-2023-181872

Published: 2023

Journal Articles

The Relapse Mechanisms and Genomic Landscape Differ in KMT2A -r Pediatric Leukemia in Relation to Relapse Time

Louise Ahlgren, Mattias Pilheden, Helena Sturesson, Varsha Singh, Qirui Zhang, Michael Walsh, Guangchun Song, Anders Castor, Cornelis Jan Pronk, Pauline Schneider, Ronald W. Stam, Gisela Barbany, Katja Pokrovskaja Tamm, Jonas Abrahamsson, Linda Fogelstrand, Olli Lohi, Jing Ma, Jinghui Zhang, Anna K. Hagstroem-Andersson

Blood (2023) 142 (Supplement 1): 2978.

https://doi.org/10.1182/blood-2023-185044

Published: 2023

Journal Articles

Heterogeneous Gene Fusion Transcripts Found in t(7;12)(q36;p13) Acute Myeloid Leukemia but with Similar Gene Expression Profile

Anders Östlund, Anna Staffas, Ulrika Norén-Nyström, Henrik Hasle, Linda Fogelstrand, Jonas Abrahamsson, Lars Palmqvist

Blood (2023) 142 (Supplement 1): 1560.

https://doi.org/10.1182/blood-2023-179814

Published: 2023

Journal Articles

Chip-AML22 Master Protocol: An Open-Label Clinical Trial in Newly Diagnosed Pediatric De Novo Acute Myeloid Leukemia (AML) Patients Including a Linked Phase II Trial with Quizartinib in FLT3 -ITD/ NPM1 wt Patients - a Study By the NOPHO-DB-SHIP Consortium

Blood (2023) 142 (Supplement 1): 1532.

https://doi.org/10.1182/blood-2023-181792

Published: 2023

Journal Articles

Targeting the WT1 mut -M ir-193a Transcriptional Axis with INT-1B3, a Novel Lipid Nanoparticle-Formulated Mir -193a-3p Mimic in Acute Myeloid Leukemia

Blood (2022) 140 (Supplement 1): 6224–6225.

https://doi.org/10.1182/blood-2022-157833

Published: 2022

Journal Articles

The Rise and Fall of Leukemia Clones in Longitudinal Samples from Diagnosis to Relapse in KMT2A- rearranged Infant and Childhood Leukemia

Louise Ahlgren, Mattias Pilheden, Helena Sturesson, Varsha Singh, Qirui Zhang, Anders Castor, Cornelis Jan Pronk, Gisela Barbany, Katja Pokrovskaja Tamm, Linda Fogelstrand, Michael P Walsh, Guangchun Song, Jinghui Zhang, Jing Ma, Anna Hagstroem-Andersson

Blood (2022) 140 (Supplement 1): 9189–9190.

https://doi.org/10.1182/blood-2022-165869

Published: 2022

Journal Articles

Patient-Tailored Measurable Residual Disease Monitoring in Peripheral Blood Using Deep Sequencing and Droplet Digital PCR for Early Detection of Relapse in Childhood Acute Myeloid Leukemia: A NOPHO-DBH Collaborative Study

Anne-Sofie Skou, Kristian Løvvik Juul-Dam, Erik Delsing Malmberg, Anna Rehammar, Anastasia Soboli, Azadeh Anbarlou, Erik Kristiansson, Jonas Abrahamsson, Bernward Zeller, Kirsi Jahnukainen, Edwin Sonneveld, Birgitte Lausen, Anni Aggerholm, Hans Beier Ommen, Henrik Hasle, Linda Fogelstrand

Blood (2021) 138 (Supplement 1): 3457.

https://doi.org/10.1182/blood-2021-153411

Published: 2021

Journal Articles

The Molecular Landscape of KMT2A -Rearranged Leukemia from Infancy to Adulthood Reveals Age and Leukemia-Specific Mutational Patterns

Blood (2021) 138 (Supplement 1): 3479.

https://doi.org/10.1182/blood-2021-152082

Published: 2021

Journal Articles

DNA-Based Methods for Measurable Residual Disease Detection in NPM1 -Mutated Acute Myeloid Leukemia; Establishment of Cut-Offs for qPCR, Digital Droplet PCR and Targeted Deep Sequencing

Louise Pettersson, Sofie Johansson Alm, Alvar Almstedt, Vladimir Lazarevic, Gustav Orrsjö, Giti Shah-Barkhordar, Linda Fogelstrand, Mats Ehinger

Blood (2020) 136 (Supplement 1): 6.

https://doi.org/10.1182/blood-2020-138675

Published: 2020

Journal Articles

Impact of Minimal Residual Disease (MRD) Assessed before Transplantation on the Outcome of Children with Acute Myeloid Leukemia Given an Allograft: A Retrospective Study By the I-BFM Study Group

Martina Pigazzi, PhD, Maddalena Benetton, Christiane Walter, MSc, Maria Hansen, Anne-Sofie Skou, MD, Ambra Da Ros, Anna Marchetti, Katia Polato, Mattia Belloni, Claudia Tregnago, PhD, Jonas Abrahamsson, MD PhD, Linda Fogelstrand, Nils Von Neuhoff, PhD, Dirk Reinhardt, MDPhD, Henrik Hasle, PhD, Franco Locatelli, MD, Pietro Merli, MD

Blood (2020) 136 (Supplement 1): 38–39.

https://doi.org/10.1182/blood-2020-137424

Published: 2020

Journal Articles

The Translocation t(7;12)(q36;p13) Induces Myeloid Leukemia in Immuno-Compromised but Not Immunocompetent Mice

Ahmed Waraky, PhD MSc, BSc, Anders Östlund, MSc, BSc, Laleh Arabanian, PhD, Tina Nilsson, MSc, BSc, Linda Fogelstrand, Lars Palmqvist, MD PhD

Blood (2019) 134 (Supplement_1): 2707.

https://doi.org/10.1182/blood-2019-123019

Published: 2019

Journal Articles

Recreation of t(7;12)(q36;p13) in Human Induced Pluripotent Stem Cells Using CRISPR/Cas9 Generates a Useful Model for Studying Acute Myeloid Leukemia

Tina Nilsson, MSc, BSc, Ahmed Waraky, PhD MSc, BSc, Anders Östlund, MSc, BSc, Laleh Arabanian, PhD, Julia Asp, PhD, Linda Fogelstrand, Lars Palmqvist, MD PhD

Blood (2019) 134 (Supplement_1): 2736.

https://doi.org/10.1182/blood-2019-123004

Published: 2019

Journal Articles

Patient-Tailored Deep Sequencing of Peripheral Blood Enables Early Detection of Relapse in Childhood Acute Myeloid Leukemia

Kristian Løvvik Juul-Dam, MD, Erik Delsing Malmberg, Anna Rehammar, Erik Kristiansson, Jonas Abrahamsson, Anni Aggerholm, Marta Maria Dirdal, Kirsi Jahnukainen, Birgitte Lausen, Hans Beier Ommen, Henrik Hasle, Linda Fogelstrand

Blood (2019) 134 (Supplement_1): 1456.

https://doi.org/10.1182/blood-2019-124970

Published: 2019

Journal Articles

Quantification of Fusion Transcripts Reveals Slower Treatment Kinetics As Compared with Multiparameter Flow Cytometry during Induction Treatment of Acute Myeloid Leukemia in Children

Lene Karlsson, MD, Charlotte Guldborg Nyvold, Lars Palmqvist, Professor, Anne Tierens, MD PhD, Henrik Hasle, MD, Birgitte Lausen, MD PhD, Olafur G. Jonsson, MD PhD, Gitte Wulff Juergensen, MD, Lene Hyldahl Ebbesen, MD PhD, Florian Kuchenbauer, MD PhD, Erik Forestier, MD PhD, Jonas Abrahamsson, Linda Fogelstrand, MD PhD

Blood (2018) 132 (Supplement 1): 2814.

https://doi.org/10.1182/blood-2018-99-116618

Published: 2018

Journal Articles

Members of the microRNA-106a-363 Cluster Associate with Unfavorable Outcome in Adult Acute Myeloid Leukemia Patients and Promote Leukemogenesis in vivo through Increased Metabolic Activity

Nadine Sperb, MSc, Kathrin Krowiorz, Sarah Grasedieck, MSc, Christoph Rueß, MSc, Nicole Pochert, MSc, Edith Schneider, PhD, Pegah Johansson, PhD, Erik Delsing Malmberg, MD, Laleh Arabanian, PhD, Tobias Maetzig, PhD, Linda Fogelstrand, MD PhD, Hartmut Döhner, MD, Lars Palmqvist, Professor, Reinhild Rösler, PhD, Sebastian Wiese, PhD, Enrico Calzia, Prof. Dr., Arefeh Rouhi, PhD, Florian Kuchenbauer, MD PhD

Blood (2018) 132 (Supplement 1): 3924.

https://doi.org/10.1182/blood-2018-99-116035

Published: 2018

Journal Articles

Measurable Residual Disease Assessment By qPCR in Peripheral Blood Is an Informative Tool for Disease Surveillance in Childhood Acute Myeloid Leukemia

Kristian Juul-Dam, MD, Hans Beier Ommen, Charlotte Guldborg Nyvold, Christiane Walter, Helen Vålerhaugen, Veli Kairisto, Jonas Abrahamsson, Sofie Johansson Alm, Kirsi Jahnukainen, Birgitte Lausen, Dirk Reinhardt, Bernward Zeller, Nils Von Neuhoff, Linda Fogelstrand, MD PhD, Henrik Hasle, MD

Blood (2018) 132 (Supplement 1): 2754.

https://doi.org/10.1182/blood-2018-99-119642

Published: 2018

Journal Articles

Accurate and Sensitive Analysis of Minimal Residual Disease in Acute Myeloid Leukemia Using Deep Sequencing of Single Nucleotide Variations

Erik Delsing Malmberg, MD, Mariana Buongermino Pereira, Anna Rehammar, Jonas Abrahamsson, MD PhD, Tore Samuelsson, Professor, Sara Ståhlman, Julia Asp, PhD, Lars Palmqvist, Professor, Erik Kristiansson, PhD, Linda Fogelstrand, MD PhD

Blood (2017) 130 (Supplement 1): 2700.

https://doi.org/10.1182/blood.V130.Suppl_1.2700.2700

Published: 2017

Journal Articles

Up-Regulation of Flt3 Is a Passive Event in Hoxa9/Meis1-Induced Acute Myeloid Leukemia

Anna Staffas, PhD, Yuan Wei, MD PhD, Laleh Arabanian, Ann Jansson, Sara Ståhlman, Susanne Li, Linda Fogelstrand, MD PhD, Jörg Cammenga, MD PhD, Florian Kuchenbauer, MD PhD, Lars Palmqvist, MD PhD

Blood (2015) 126 (23): 2441.

https://doi.org/10.1182/blood.V126.23.2441.2441

Published: 2015

Journal Articles

The Role of microRNA-155 in Mouse Models of MLL -AML

Anna Staffas, PhD, Edith Schneider, MSc, Linda Fogelstrand, MD PhD, Linda Röhner, Michael Heuser, MD, Konstanze Döhner, MD, Hartmut Döhner, MD, Arefeh Rouhi, PhD, Florian Kuchenbauer, MD PhD, Lars Palmqvist, MD PhD

Blood (2015) 126 (23): 2446.

https://doi.org/10.1182/blood.V126.23.2446.2446

Published: 2015

NARROW

Deep Sequencing Is a Widely Applicable Tool for Relapse Prediction in Acute Myeloid Leukemia with Mutated NPM1

Nucleophosmin (NPM1) Type D Genotype Is Associated with Distinct Outcome in Acute Myeloid Leukemia - an AIEOP-BFM and COG-SWOG Intergroup Collaboration

The Relapse Mechanisms and Genomic Landscape Differ in KMT2A -r Pediatric Leukemia in Relation to Relapse Time

Heterogeneous Gene Fusion Transcripts Found in t(7;12)(q36;p13) Acute Myeloid Leukemia but with Similar Gene Expression Profile

Chip-AML22 Master Protocol: An Open-Label Clinical Trial in Newly Diagnosed Pediatric De Novo Acute Myeloid Leukemia (AML) Patients Including a Linked Phase II Trial with Quizartinib in FLT3 -ITD/ NPM1 wt Patients - a Study By the NOPHO-DB-SHIP Consortium

Targeting the WT1 mut -M ir-193a Transcriptional Axis with INT-1B3, a Novel Lipid Nanoparticle-Formulated Mir -193a-3p Mimic in Acute Myeloid Leukemia

The Rise and Fall of Leukemia Clones in Longitudinal Samples from Diagnosis to Relapse in KMT2A- rearranged Infant and Childhood Leukemia

Patient-Tailored Measurable Residual Disease Monitoring in Peripheral Blood Using Deep Sequencing and Droplet Digital PCR for Early Detection of Relapse in Childhood Acute Myeloid Leukemia: A NOPHO-DBH Collaborative Study

The Molecular Landscape of KMT2A -Rearranged Leukemia from Infancy to Adulthood Reveals Age and Leukemia-Specific Mutational Patterns

DNA-Based Methods for Measurable Residual Disease Detection in NPM1 -Mutated Acute Myeloid Leukemia; Establishment of Cut-Offs for qPCR, Digital Droplet PCR and Targeted Deep Sequencing

Impact of Minimal Residual Disease (MRD) Assessed before Transplantation on the Outcome of Children with Acute Myeloid Leukemia Given an Allograft: A Retrospective Study By the I-BFM Study Group

The Translocation t(7;12)(q36;p13) Induces Myeloid Leukemia in Immuno-Compromised but Not Immunocompetent Mice

Recreation of t(7;12)(q36;p13) in Human Induced Pluripotent Stem Cells Using CRISPR/Cas9 Generates a Useful Model for Studying Acute Myeloid Leukemia

Patient-Tailored Deep Sequencing of Peripheral Blood Enables Early Detection of Relapse in Childhood Acute Myeloid Leukemia

Quantification of Fusion Transcripts Reveals Slower Treatment Kinetics As Compared with Multiparameter Flow Cytometry during Induction Treatment of Acute Myeloid Leukemia in Children

Members of the microRNA-106a-363 Cluster Associate with Unfavorable Outcome in Adult Acute Myeloid Leukemia Patients and Promote Leukemogenesis in vivo through Increased Metabolic Activity

Measurable Residual Disease Assessment By qPCR in Peripheral Blood Is an Informative Tool for Disease Surveillance in Childhood Acute Myeloid Leukemia

Accurate and Sensitive Analysis of Minimal Residual Disease in Acute Myeloid Leukemia Using Deep Sequencing of Single Nucleotide Variations

Up-Regulation of Flt3 Is a Passive Event in Hoxa9/Meis1-Induced Acute Myeloid Leukemia

The Role of microRNA-155 in Mouse Models of MLL -AML

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