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Journal Articles

Extended Mutational Profiling By MSK-IMPACT TM Identifies Mutations Predicting Thromboembolic Risk in Patients with Solid Tumor Malignancy

Andrew Dunbar, MD, Kelly Bolton, MD PhD, Sean M. Devlin, PhD, Francisco Sanchez-Vega, PhD, Jianjiong Gao, PhD, Jodi V. Mones, MD, Jonathan M. Wills, BA, Daniel Kelly, MS, Mirko Farina, MD, Sirish Kishore, MD, Krishna Juluru, MD, Neil Iyengar, MD, David M. Hyman, MD, Ahmet Zehir, PhD, Wungki Park, MD, Alok A Khorana, MD, Gerald A. Soff, MD, Simon Mantha, MDMPH

Blood (2019) 134 (Supplement_1): 633.

https://doi.org/10.1182/blood-2019-124242

Published: 2019

Journal Articles

Oncologic Therapy for Solid Tumors Alters the Risk of Clonal Hematopoiesis

Blood (2018) 132 (Supplement 1): 747.

https://doi.org/10.1182/blood-2018-99-119530

Published: 2018

Journal Articles

Activating Mutations in CSF1R and Additional Receptor Tyrosine Kinases in Sporadic and Familial Histiocytic Neoplasms

Benjamin H Durham, MD BS, Estibaliz Lopez-Rodrigo, MD, David H Abramson, MD, Jennifer Picarsic, MD, Alessandro Pastore, Diana Mandelker, MD PhD, Michael Francis Walsh, MD, Maria E Arcila, MD, Marc Ladanyi, MD, David Solit, MD, Michael F. Berger, PhD, David M. Hyman, MD, Michelle Ki, BSc, Ira Dunkel, MD, Frederic Geissmann, MD PhD, Eli L Diamond, MD, Omar I Abdel-Wahab, MD

Blood (2018) 132 (Supplement 1): 49.

https://doi.org/10.1182/blood-2018-99-114248

Published: 2018

Journal Articles

Characterization of Ntrk fusions and Therapeutic Response to Ntrk Inhibition in Hematologic Malignancies

Blood (2017) 130 (Supplement 1): 794.

https://doi.org/10.1182/blood.V130.Suppl_1.794.794

Published: 2017

Journal Articles

Phase 2 Trial of Single-Agent Cobimetinib for Adults with BRAF V600-Mutant and Wild-Type Histiocytic Disorders

Eli L Diamond, MD, Benjamin H Durham, MD BS, Ahmet Dogan, MD PhD, David M. Hyman, MD, Raajit K. Rampal, MD PhD, Gary Ulaner, MD, Lynn Brody, MD, Omar Abdel-Wahab, MD

Blood (2017) 130 (Supplement 1): 257.

https://doi.org/10.1182/blood.V130.Suppl_1.257.257

Published: 2017

Journal Articles

Population-Scale Identification of Clonal Hematopoiesis Derived Mutations in Solid Tumor Mutation Profiling

Ryan Ptashkin, MS, Catherine C. Coombs, MD, David M. Hyman, MD, David Solit, MD, Jose Baselga, MD, Maria E. Arcila, Marc Ladanyi, MD, Ross L. Levine, MD, Michael F. Berger, PhD, Ahmet Zehir, PhD

Blood (2017) 130 (Supplement 1): 2418.

https://doi.org/10.1182/blood.V130.Suppl_1.2418.2418

Published: 2017

Journal Articles

Mutational Analysis of Clonal Hematopoiesis in Solid Tumor Patients Illustrates the Critical Role of Systemic Anti-Cancer Therapies in the Evolution of Somatic Leukemia Disease Alleles

Catherine C. Coombs, MD, Ahmet Zehir, PhD, Sean Devlin, PhD, Ashwin Kishtagari, MD, David M. Hyman, David Solit, MD, Mark Robson, MD, Jose Baselga, MD PhD, Maria Arcila, MD, Martin S. Tallman, MD, Ross L. Levine, MD, Michael Berger, PhD

Blood (2016) 128 (22): 37.

https://doi.org/10.1182/blood.V128.22.37.37

Published: 2016

Journal Articles

Vemurafenib in Patients with Erdheim-Chester Disease (ECD) and Langerhans Cell Histiocytosis (LCH) Harboring BRAF V600 Mutations: A Cohort of the Histology-Independent VE-Basket Study

Blood (2016) 128 (22): 480.

https://doi.org/10.1182/blood.V128.22.480.480

Published: 2016

Journal Articles

Frequent Clinical Overlap of Histiocytic Neoplasms and WHO-Classified Myeloid Malignancies Leads to Functional Insights into the Cell-of-Origin of Histiocytoses

Benjamin Heath Durham, MD BS, Akihide Yoshimi, MD PhD, Matthias Papo, Young Rock Chung, MS, Neval Ozkaya, MD, Chezi Ganzel, Ahmet Dogan, David M. Hyman, Christopher Y. Park, MD PhD, Raajit K. Rampal, MD, PhD, Damien Roos Weil, Francois Michel Lemoine, MD PhD, Zahir Amoura, Olivier A. Bernard, PhD, Eli L. Diamond, MD, Jean-François Emile, MD PhD, Julien Haroche, MD PhD, Omar Abdel-Wahab, MD

Blood (2016) 128 (22): 951.

https://doi.org/10.1182/blood.V128.22.951.951

Published: 2016

Journal Articles

Next-Generation Sequencing of Matched Normal Blood Identifies Clonal Hematopoiesis in a Significant Subset of Solid Tumor Patients without Hematologic Malignancies

Catherine C. Coombs, MD, Ahmet Zehir, PhD, Sean Devlin, PhD, Sumit Middha, PhD, Donavan Cheng, PhD, Ashwin Kishtagari, MD, David M. Hyman, David Solit, MD, Mark Robson, MD, Jose Baselga, MD PhD, Maria Arcila, MD, Mark Ladanyi, MD, Martin S Tallman, MD, Ross L. Levine, MD, Michael Berger, PhD

Blood (2015) 126 (23): 2447.

https://doi.org/10.1182/blood.V126.23.2447.2447

Published: 2015

Journal Articles

Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms

Benjamin Heath Durham, MD BS, Eli L. Diamond, MD, Julien Haroche, MD PhD, Zhan Yao, PhD, Jing Ma, PhD, Sameer A. Parikh, MD, John Choi, Eunhee Kim, PhD, Fleur Cohen-Aubart, Stanley Chun-Wei Lee, Yijun Gao, Jean-Baptiste Micol, MD, Patrick Campbell, MD PhD, Michael P. Walsh, Brooke Sylvester, Igor Dolgalev, Aminova Olga, Adriana Heguy, Paul Zappile, Joy Nakitandwe, BSc,MSc,PhD, James Dalton, BS, David W Ellison, MD, Juvianee Estrada-Veras, Mario Lacouture, William A. Gahl, MD PhD, Phil Stephens, PhD, Vincent A. Miller, MD, Jeffrey Ross, Siraj Ali, Sebastien Héritier, Jean Donadieu, MD PhD, David Solit, MD, David M. Hyman, Jose Baselga, MD PhD, Filip Janku, MDPhD, Barry S. Taylor, PhD, Christopher Y. Park, MD, PhD, Ahmet Dogan, MD PhD, Zahir Amoura, Jean-Francois Emile, Raajit K. Rampal, MD, PhD, Neal Rosen, MD PhD, Tanja A. Gruber, MD PhD, Omar Abdel-Wahab

Blood (2015) 126 (23): 481.

https://doi.org/10.1182/blood.V126.23.481.481

Published: 2015

Journal Articles

Vemurafenib (VEM) in Relapsed Refractory Multiple Myeloma Harboring BRAF V600 Mutations (V600m): A Cohort of the Histology-Independent VE-Basket Study

Noopur Raje, Ian Chau, David M. Hyman, Vincent Ribrag, Jean-Yves Blay, Josep Tabernero, Maria Elena Elez-Fernandez, Jürgen S. Wolf, Florin Sirzen, Andrew Yee, Jason Faris, Martin Kaiser, Heather Landau, Jean-Marie Michot, Luisa Veronese, Martina Makrutzki, Susan Francis Lasserre, Igor Puzanov, Jose Baselga

Blood (2015) 126 (23): 4263.

https://doi.org/10.1182/blood.V126.23.4263.4263

Published: 2015

Journal Articles

The Efficacy of Vemurafenib in Erdheim-Chester Disease and Langerhans Cell Histiocytosis: Preliminary Results from VE-Basket Study

David M. Hyman, MD, Eli Diamond, Vivek Subbiah, MD, Jean-Yves Blay, MD PhD, A. Craig Lockhart, Omar Abdel-Wahab, MD, Florin Sirzen, Maria Luisa Veronese, MD, Susan Frances Laserre, Elena Elez, Jose Baselga, MD PhD

Blood (2014) 124 (21): 635.

https://doi.org/10.1182/blood.V124.21.635.635

Published: 2014

Journal Articles

Unraveling the Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms through Whole Exome Sequencing

Benjamin Durham, MD, Jing Ma, PhD, Eunhee Kim, PhD, John K. Choi, MD, Patrick Campbell, MD PhD, Juvianee Estrada-Veras, MD, Michael P Walsh, PhD, Mario E Lacouture, MD, Young Rock Chung, MS, Joy Nakitandwe, PhD, Eli Diamond, David M. Hyman, MD, Raajit K. Rampal, MD PhD, Minal Patel, Christopher Y. Park, MD PhD, Tanja A. Gruber, MD PhD, Omar Abdel-Wahab, MD

Blood (2014) 124 (21): 1887.

https://doi.org/10.1182/blood.V124.21.1887.1887

Published: 2014

Journal Articles

Prospective Blinded Study of BRAF V600E Mutation Detection in Cell-Free DNA of Patients with Systemic Histiocytic Disorders

David M. Hyman, MD, Eli Diamond, Cecile Rose Vibat, Latifa Hassaine, Jason Poole, Minal Patel, Veronica Holley, Goran Cabrilo, Timothy T. Lu, Maria Arcila, MD, Young Rock Chung, MS, Raajit K. Rampal, MD PhD, Funda Meric-Bernstam, MD, Jose Baselga, MD PhD, Razelle Kurzrock, MD, Mark Erlander, Filip Janku, MD PhD, Omar Abdel-Wahab, MD

Blood (2014) 124 (21): 1833.

https://doi.org/10.1182/blood.V124.21.1833.1833

Published: 2014

Journal Articles

Recurrent RAS and PIK3CA mutations in Erdheim-Chester disease

Blood (2014) 124 (19): 3016–3019.

https://doi.org/10.1182/blood-2014-04-570937

Published: 2014

Includes: Supplemental data

Journal Articles

Consensus guidelines for the diagnosis and clinical management of Erdheim-Chester disease

Eli L. Diamond, Lorenzo Dagna, David M. Hyman, Giulio Cavalli, Filip Janku, Juvianee Estrada-Veras, Marina Ferrarini, Omar Abdel-Wahab, Mark L. Heaney, Paul J. Scheel, Nancy K. Feeley, Elisabetta Ferrero, Kenneth L. McClain, Augusto Vaglio, Thomas Colby, Laurent Arnaud, Julien Haroche

Blood (2014) 124 (4): 483–492.

https://doi.org/10.1182/blood-2014-03-561381

Published: 2014

Includes: Supplemental data

Journal Articles

ABT-888 Plus Bendamustine Is Safe and Has Shown Preliminary Efficacy In Patients With Lymphoma

Blood (2013) 122 (21): 4366.

https://doi.org/10.1182/blood.V122.21.4366.4366

Published: 2013

Journal Articles

Detection of an NRAS mutation in Erdheim-Chester disease

Eli L. Diamond, Omar Abdel-Wahab, Elena Pentsova, Laetitia Borsu, April Chiu, Julie Teruya-Feldstein, David M. Hyman, Marc Rosenblum

Blood (2013) 122 (6): 1089–1091.

https://doi.org/10.1182/blood-2013-02-482984

Published: 2013

NARROW

Extended Mutational Profiling By MSK-IMPACT TM Identifies Mutations Predicting Thromboembolic Risk in Patients with Solid Tumor Malignancy

Oncologic Therapy for Solid Tumors Alters the Risk of Clonal Hematopoiesis

Activating Mutations in CSF1R and Additional Receptor Tyrosine Kinases in Sporadic and Familial Histiocytic Neoplasms

Characterization of Ntrk fusions and Therapeutic Response to Ntrk Inhibition in Hematologic Malignancies

Phase 2 Trial of Single-Agent Cobimetinib for Adults with BRAF V600-Mutant and Wild-Type Histiocytic Disorders

Population-Scale Identification of Clonal Hematopoiesis Derived Mutations in Solid Tumor Mutation Profiling

Mutational Analysis of Clonal Hematopoiesis in Solid Tumor Patients Illustrates the Critical Role of Systemic Anti-Cancer Therapies in the Evolution of Somatic Leukemia Disease Alleles

Vemurafenib in Patients with Erdheim-Chester Disease (ECD) and Langerhans Cell Histiocytosis (LCH) Harboring BRAF V600 Mutations: A Cohort of the Histology-Independent VE-Basket Study

Frequent Clinical Overlap of Histiocytic Neoplasms and WHO-Classified Myeloid Malignancies Leads to Functional Insights into the Cell-of-Origin of Histiocytoses

Next-Generation Sequencing of Matched Normal Blood Identifies Clonal Hematopoiesis in a Significant Subset of Solid Tumor Patients without Hematologic Malignancies

Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms

Vemurafenib (VEM) in Relapsed Refractory Multiple Myeloma Harboring BRAF V600 Mutations (V600m): A Cohort of the Histology-Independent VE-Basket Study

The Efficacy of Vemurafenib in Erdheim-Chester Disease and Langerhans Cell Histiocytosis: Preliminary Results from VE-Basket Study

Unraveling the Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms through Whole Exome Sequencing

Prospective Blinded Study of BRAF V600E Mutation Detection in Cell-Free DNA of Patients with Systemic Histiocytic Disorders

Recurrent RAS and PIK3CA mutations in Erdheim-Chester disease

Consensus guidelines for the diagnosis and clinical management of Erdheim-Chester disease

ABT-888 Plus Bendamustine Is Safe and Has Shown Preliminary Efficacy In Patients With Lymphoma

Detection of an NRAS mutation in Erdheim-Chester disease

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American Society of Hematology

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ASH Publications

American Society of Hematology

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